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The map label for this gene is pcaR [H]

Identifier: 54025495

GI number: 54025495

Start: 3736958

End: 3737770

Strand: Reverse

Name: pcaR [H]

Synonym: nfa35250

Alternate gene names: 54025495

Gene position: 3737770-3736958 (Counterclockwise)

Preceding gene: 54025496

Following gene: 54025489

Centisome position: 62.08

GC content: 71.83

Gene sequence:

>813_bases
ATGGTGGCAGCACAGGACGGCGAACGGGGCGCGCACCACGTGCAGTCGCTGGATCGCGGTCTGGCCGTCATCCGCGCCTT
CGACGCCGAGCATCCCGAGCTGACGCTGTCGGAGGTGGCCCGGCGGACCGGTCTGGCCAGGGCGGCGGCGCGCCGATTCC
TGCTCACCCTGGCCGATCTCGGTTACGTGCGCACCGACGGCAAGAACTTCGCGCTGACGGCGCGGGTGCTCGAACTCGGC
TACGCCTACCTGTCGAGCATGGGTCTGCCGGACGTGGCGCAGCCGCACCTCGAGCAGCTCTCGCGCACGGTGGCGGAGTC
GTCGTCGGTCTCGGTGCTCGACGGCGCCGACATCGTCTACGTGGCACGGGTGGCCGTCTCGCGGATCATGACGGTCCGCA
TCGACATCGGCACCCGCTTCCCCGCCTACGCCACGTCGATGGGTCACGTGTTGCTGGCCGGGCTGACCCCCGACGAACTC
GACGCCTACCTGGCCGCGACCACGTTGGCGCCGCGCACCCCGCACACCACGGTGTCGGAGGCGGCGTTGCGTGCGGAACT
GGACGCCGTTCGCGCGCAAGGGTATTCGCTGGTCGACCAGGAACTCGAGGAGGGGCTGCGCTCGGTCGCCGCCCCGATCC
GCGACCGCGCGGGCACGGTGATCGCCGCGGTGAACATCTCCACCCAGGCGACCCGGCACAGCGTCGCCTCGATCCGGGCG
GATCTGGTACCGCCGCTGCTCGCGACGGCCGCGCGGATCGAGCAGGATCTGCGCAACACGAACGGCCCCGCCCGGGGTCG
GGGCGGGGCCTGA

Upstream 100 bases:

>100_bases
GAGGAGACCGCCGAACTGCTCGGGCTCTGACCACCGATACCGCGCACACCTGGGCGTATCGTGAACGCCGGTCGGGGAAT
CGGCGGCGAGAGGATGCGGG

Downstream 100 bases:

>100_bases
GCCCGGGCGGGCGGTAGCCGCCGGGTCGGGATGTGGCGGCGCGGCGCCGGTGATGGGGCTATCCGACGCGGGTGAGCGAG
TCCAGGAACGCGGCGAGGGC

Product: putative transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MVAAQDGERGAHHVQSLDRGLAVIRAFDAEHPELTLSEVARRTGLARAAARRFLLTLADLGYVRTDGKNFALTARVLELG
YAYLSSMGLPDVAQPHLEQLSRTVAESSSVSVLDGADIVYVARVAVSRIMTVRIDIGTRFPAYATSMGHVLLAGLTPDEL
DAYLAATTLAPRTPHTTVSEAALRAELDAVRAQGYSLVDQELEEGLRSVAAPIRDRAGTVIAAVNISTQATRHSVASIRA
DLVPPLLATAARIEQDLRNTNGPARGRGGA

Sequences:

>Translated_270_residues
MVAAQDGERGAHHVQSLDRGLAVIRAFDAEHPELTLSEVARRTGLARAAARRFLLTLADLGYVRTDGKNFALTARVLELG
YAYLSSMGLPDVAQPHLEQLSRTVAESSSVSVLDGADIVYVARVAVSRIMTVRIDIGTRFPAYATSMGHVLLAGLTPDEL
DAYLAATTLAPRTPHTTVSEAALRAELDAVRAQGYSLVDQELEEGLRSVAAPIRDRAGTVIAAVNISTQATRHSVASIRA
DLVPPLLATAARIEQDLRNTNGPARGRGGA
>Mature_270_residues
MVAAQDGERGAHHVQSLDRGLAVIRAFDAEHPELTLSEVARRTGLARAAARRFLLTLADLGYVRTDGKNFALTARVLELG
YAYLSSMGLPDVAQPHLEQLSRTVAESSSVSVLDGADIVYVARVAVSRIMTVRIDIGTRFPAYATSMGHVLLAGLTPDEL
DAYLAATTLAPRTPHTTVSEAALRAELDAVRAQGYSLVDQELEEGLRSVAAPIRDRAGTVIAAVNISTQATRHSVASIRA
DLVPPLLATAARIEQDLRNTNGPARGRGGA

Specific function: Positive regulator of all genes within the pca regulon, pcaBDC, pcaIJ and pcaF. Also required for the chemotactic response to aromatic compounds [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=253, Percent_Identity=33.201581027668, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1786468, Length=221, Percent_Identity=31.6742081447964, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI87082359, Length=223, Percent_Identity=30.9417040358744, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1789999, Length=259, Percent_Identity=28.957528957529, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786715, Length=227, Percent_Identity=26.8722466960352, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788581, Length=159, Percent_Identity=28.9308176100629, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790752, Length=192, Percent_Identity=21.875, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012794
- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 28695; Mature: 28695

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAAQDGERGAHHVQSLDRGLAVIRAFDAEHPELTLSEVARRTGLARAAARRFLLTLADL
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
GYVRTDGKNFALTARVLELGYAYLSSMGLPDVAQPHLEQLSRTVAESSSVSVLDGADIVY
CEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEECCCHHHH
VARVAVSRIMTVRIDIGTRFPAYATSMGHVLLAGLTPDELDAYLAATTLAPRTPHTTVSE
HHHHHHHHHHEEEEECCCCCCHHHHHHCCEEEECCCHHHHHHHHHHHHCCCCCCCCHHHH
AALRAELDAVRAQGYSLVDQELEEGLRSVAAPIRDRAGTVIAAVNISTQATRHSVASIRA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHH
DLVPPLLATAARIEQDLRNTNGPARGRGGA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MVAAQDGERGAHHVQSLDRGLAVIRAFDAEHPELTLSEVARRTGLARAAARRFLLTLADL
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
GYVRTDGKNFALTARVLELGYAYLSSMGLPDVAQPHLEQLSRTVAESSSVSVLDGADIVY
CEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEECCCHHHH
VARVAVSRIMTVRIDIGTRFPAYATSMGHVLLAGLTPDELDAYLAATTLAPRTPHTTVSE
HHHHHHHHHHEEEEECCCCCCHHHHHHCCEEEECCCHHHHHHHHHHHHCCCCCCCCHHHH
AALRAELDAVRAQGYSLVDQELEEGLRSVAAPIRDRAGTVIAAVNISTQATRHSVASIRA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHH
DLVPPLLATAARIEQDLRNTNGPARGRGGA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083169 [H]