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The map label for this gene is yagE [C]

Identifier: 54025474

GI number: 54025474

Start: 3716027

End: 3716941

Strand: Reverse

Name: yagE [C]

Synonym: nfa35040

Alternate gene names: 54025474

Gene position: 3716941-3716027 (Counterclockwise)

Preceding gene: 54025482

Following gene: 54025473

Centisome position: 61.73

GC content: 70.38

Gene sequence:

>915_bases
ATGACCACAGCCTCTCCGCAGGACATCGCCGCACGTCTCGGCTCCGGACTCCTCTCCTTCCCGGTCACCCACCTGCGGGC
CGACGGCTCCTTCGACGAGGCCGCCTACCGCGAGCACATCGCCTGGCTGGGCGGCCACGACGCGGCCGGGCTGTTCGCCG
CGGGCGGCACCGGCGAGTTCTTCTCGCTGACCCCGGCCGAGGTCGAGCAGGTGGTCACCGCCGCGGTGCGGGAGGCGCCG
GAGGGGCTGCCCGTCATCGCCCCGGCCGGGTACGGCACCGCCACCGCGATCGAGATGGCGCGCGCCGCCGAACGCGCCGG
TGCGCACGGCATCCTGCTGTTGCCGCCCTACCTCACCGAGGCCGGGCAGCGCGGGCTCGTCGAGCACGTGCGCCAGGTCT
GCGCGGCGACCGATCTCGGTGTCATCGTCTACTCGCGGGCCAACGCCGCCTACTCCGCGCCCGCGGTCGCCGAACTGGCC
GACCGCTGCCCGAACCTGATCGGGTTCAAGGACGGCATCGGCAACATCGAACAGATGACCCGGATCTACGCCGAGGTCGG
CGACCGGCTGTTCTATGTCGGCGGATTGCCCACCGCGGAGATGTTCGCGCTGCCCTACCTGGCGTTGGGCGTGACCACCT
ACTCCTCGGCGATCTTCAACTTCGTGCCGCAGTTCGCGCTCGACTTCTATCGCGCGGTGCGGCGCAACGACGCCCCGTTC
GTGCTCAACGCGCTCGCGGAGTTCGTGATCCCCTACTGCGAGCTGCGCAACCGCGAGCCCGGCTACGCGGTGAGCATCAT
CAAGGCGGGTATGACGGTGATCGGACGTCCCGCGGGTCCGGTCCGCAGCCCGCTGACCGACCTGGACGACGCCGAACTCG
CCGAACTGGCCGATCTCGTGAAGAAGGTGAGCTGA

Upstream 100 bases:

>100_bases
ACAGACCTTGTATTGATAGATAGGAAATCAGTGTTGGACGTGAATCATAAGCCGTTCCTAGGGTGAGGTCAGCAGGCCAC
CCCGAACAGGAGCGCACACC

Downstream 100 bases:

>100_bases
TGACCGCCGCGACCACCGAACAGCTGACGGGGGCGAACCTCGTCGGTGCCGCCGACGTGCCCGGCGCCGCCGCGCCGTTC
CGCGCCGTCGATCCGGCGAG

Product: 5-dehydro-4-deoxyglucarate dehydratase

Products: NA

Alternate protein names: 5-keto-4-deoxy-glucarate dehydratase; KDGDH

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MTTASPQDIAARLGSGLLSFPVTHLRADGSFDEAAYREHIAWLGGHDAAGLFAAGGTGEFFSLTPAEVEQVVTAAVREAP
EGLPVIAPAGYGTATAIEMARAAERAGAHGILLLPPYLTEAGQRGLVEHVRQVCAATDLGVIVYSRANAAYSAPAVAELA
DRCPNLIGFKDGIGNIEQMTRIYAEVGDRLFYVGGLPTAEMFALPYLALGVTTYSSAIFNFVPQFALDFYRAVRRNDAPF
VLNALAEFVIPYCELRNREPGYAVSIIKAGMTVIGRPAGPVRSPLTDLDDAELAELADLVKKVS

Sequences:

>Translated_304_residues
MTTASPQDIAARLGSGLLSFPVTHLRADGSFDEAAYREHIAWLGGHDAAGLFAAGGTGEFFSLTPAEVEQVVTAAVREAP
EGLPVIAPAGYGTATAIEMARAAERAGAHGILLLPPYLTEAGQRGLVEHVRQVCAATDLGVIVYSRANAAYSAPAVAELA
DRCPNLIGFKDGIGNIEQMTRIYAEVGDRLFYVGGLPTAEMFALPYLALGVTTYSSAIFNFVPQFALDFYRAVRRNDAPF
VLNALAEFVIPYCELRNREPGYAVSIIKAGMTVIGRPAGPVRSPLTDLDDAELAELADLVKKVS
>Mature_303_residues
TTASPQDIAARLGSGLLSFPVTHLRADGSFDEAAYREHIAWLGGHDAAGLFAAGGTGEFFSLTPAEVEQVVTAAVREAPE
GLPVIAPAGYGTATAIEMARAAERAGAHGILLLPPYLTEAGQRGLVEHVRQVCAATDLGVIVYSRANAAYSAPAVAELAD
RCPNLIGFKDGIGNIEQMTRIYAEVGDRLFYVGGLPTAEMFALPYLALGVTTYSSAIFNFVPQFALDFYRAVRRNDAPFV
LNALAEFVIPYCELRNREPGYAVSIIKAGMTVIGRPAGPVRSPLTDLDDAELAELADLVKKVS

Specific function: Unknown

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family

Homologues:

Organism=Escherichia coli, GI1786463, Length=283, Percent_Identity=25.7950530035336, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI87082415, Length=275, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788823, Length=193, Percent_Identity=29.0155440414508, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KDGD_NOCFA (Q5YTY9)

Other databases:

- EMBL:   AP006618
- RefSeq:   YP_119716.1
- HSSP:   P63945
- ProteinModelPortal:   Q5YTY9
- GeneID:   3109509
- GenomeReviews:   AP006618_GR
- KEGG:   nfa:nfa35040
- NMPDR:   fig|247156.1.peg.3423
- HOGENOM:   HBG358848
- OMA:   RNRKKGY
- ProtClustDB:   PRK03620
- BioCyc:   NFAR247156:NFA35040-MONOMER
- BRENDA:   4.2.1.41
- HAMAP:   MF_00694
- InterPro:   IPR013785
- InterPro:   IPR017655
- InterPro:   IPR002220
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR12128
- TIGRFAMs:   TIGR03249

Pfam domain/function: PF00701 DHDPS

EC number: =4.2.1.41

Molecular weight: Translated: 32246; Mature: 32115

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTASPQDIAARLGSGLLSFPVTHLRADGSFDEAAYREHIAWLGGHDAAGLFAAGGTGEF
CCCCCHHHHHHHHCCCHHHCCHHHHCCCCCCHHHHHHHHHHHCCCCCCCCEEECCCCCCC
FSLTPAEVEQVVTAAVREAPEGLPVIAPAGYGTATAIEMARAAERAGAHGILLLPPYLTE
EECCHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHCCCCCEEEECHHHHH
AGQRGLVEHVRQVCAATDLGVIVYSRANAAYSAPAVAELADRCPNLIGFKDGIGNIEQMT
HCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHH
RIYAEVGDRLFYVGGLPTAEMFALPYLALGVTTYSSAIFNFVPQFALDFYRAVRRNDAPF
HHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
VLNALAEFVIPYCELRNREPGYAVSIIKAGMTVIGRPAGPVRSPLTDLDDAELAELADLV
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHH
KKVS
HHCC
>Mature Secondary Structure 
TTASPQDIAARLGSGLLSFPVTHLRADGSFDEAAYREHIAWLGGHDAAGLFAAGGTGEF
CCCCHHHHHHHHCCCHHHCCHHHHCCCCCCHHHHHHHHHHHCCCCCCCCEEECCCCCCC
FSLTPAEVEQVVTAAVREAPEGLPVIAPAGYGTATAIEMARAAERAGAHGILLLPPYLTE
EECCHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHCCCCCEEEECHHHHH
AGQRGLVEHVRQVCAATDLGVIVYSRANAAYSAPAVAELADRCPNLIGFKDGIGNIEQMT
HCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHH
RIYAEVGDRLFYVGGLPTAEMFALPYLALGVTTYSSAIFNFVPQFALDFYRAVRRNDAPF
HHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
VLNALAEFVIPYCELRNREPGYAVSIIKAGMTVIGRPAGPVRSPLTDLDDAELAELADLV
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHH
KKVS
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA