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The map label for this gene is CYP133B2 [H]

Identifier: 54025469

GI number: 54025469

Start: 3710749

End: 3711942

Strand: Reverse

Name: CYP133B2 [H]

Synonym: nfa34990

Alternate gene names: 54025469

Gene position: 3711942-3710749 (Counterclockwise)

Preceding gene: 54025473

Following gene: 54025467

Centisome position: 61.65

GC content: 72.19

Gene sequence:

>1194_bases
ATGTCAACACCGACCAGCCTCGACGGTCTCGATTTCGCCTTCCACGACCTACCGGACCTGCATGCCACCCTCGCCGACCT
GCGCCGCCGCGCACCCTGGGCGACGGTGCCGTTCGCGGGCTCGCGCGCGATCCTGCTGCTGACGCACGACCTGGTCGCGG
CCGCCTTCAAGGACGAGGTCACCTTCCCCGCCGCGGTCACCTACCGGCTCACCACCGGACCCGTGCTCGGGCACACCCTG
CAATGCATGCAGGGCAGGGAGCACCGCATCGCCCGCGGCATCGCCACCCCGCCGTTGCGCCGCGCCAAGGTAGCCGCACT
GGTCGAGCCGCTGCTCGAGCCGCTCGCGCACGAGCTGATCGACGACTTCGCCGACCGGGGCACCGCCGATCTGGTCGCCG
AATTCACCACCCGCTACCCGGTACTGGTGATCAGCAGACTGCTCGGCCTGCCGAACGCCGACGAGGCGACCGTGCACCGC
TGGGCACGCGATCTGTTCCACTTCCCGCTCGACCCCGACGCCGCACGGCGCGCCTCCCGCGAATTCACCGCCTACGTCAC
GCCGGTTCTCGCTGAGCGCAGACGTGCCCCGGGCGACGACCTGATCTCGCTGCTGGTCACCACCTCGGCGGAGGGGGAGC
ACCTCACCGACGAACAGGTGCTCTCGTTCCTGCGCCTGCTGTTCCCGGCCGGTGCCGACACCACGATGCTCGGGCTCGGC
AACATCCTCTCGGCGCTGCTCACCCACCCCGAGCAGCTGGCCAGGGTCGCCGCCGACCCGGACGAATGGGTGCGGTGGGC
GGTCTGGGAGGGGCTGCGATGGGAGCCCCCGGTCGGCCTGCTGCCGCGCGCCTGCCCGGAAGCCGTTGAGTGGCACGGCA
TCTCGATCCCGGCGGGCACGCCGATGATCTTCGCGATCACCGCCGCACACCGCGACCCCGGCCACTACCCCGACCCGGAT
CGGTTCGACATCACCCGGCAGGCGACGGCGATGCTCTCGTTCGGGCAGGGCCCGCACAGCTGCCCCGGCAACTGGCTCGC
CCTCGCGGAACTCACCACCGCGCTCGGCGCGTTGCTGGCGCGCCTGCCCGGACTCCGCCTGCGGCCCGGCGCCGCCGACC
GGGCCCGGGTGACCAGTCAGGTCGGCACGGCGTTGCGCGGACCGAACGCGCTGGCCGTCGAATGGGACCGCTGA

Upstream 100 bases:

>100_bases
CGACACCGACTCGGTCTTGTCAGCGGCCATCCGTCCTCTTACAGTCGGCAGTACAGTTATTCGCATCCACCAGTGCGGAT
ATTCGCATCAGGAGTTGCCG

Downstream 100 bases:

>100_bases
GTATTCAGCCCTGCGGCTGGAACCGCACCCGCACCGAGACGCCGCCGCGCTCGTCCTTGGTGGCGACGGCGTGCCCGCGC
CGGTCGATGCCGTTGATGTG

Product: cytochrome P450 monooxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MSTPTSLDGLDFAFHDLPDLHATLADLRRRAPWATVPFAGSRAILLLTHDLVAAAFKDEVTFPAAVTYRLTTGPVLGHTL
QCMQGREHRIARGIATPPLRRAKVAALVEPLLEPLAHELIDDFADRGTADLVAEFTTRYPVLVISRLLGLPNADEATVHR
WARDLFHFPLDPDAARRASREFTAYVTPVLAERRRAPGDDLISLLVTTSAEGEHLTDEQVLSFLRLLFPAGADTTMLGLG
NILSALLTHPEQLARVAADPDEWVRWAVWEGLRWEPPVGLLPRACPEAVEWHGISIPAGTPMIFAITAAHRDPGHYPDPD
RFDITRQATAMLSFGQGPHSCPGNWLALAELTTALGALLARLPGLRLRPGAADRARVTSQVGTALRGPNALAVEWDR

Sequences:

>Translated_397_residues
MSTPTSLDGLDFAFHDLPDLHATLADLRRRAPWATVPFAGSRAILLLTHDLVAAAFKDEVTFPAAVTYRLTTGPVLGHTL
QCMQGREHRIARGIATPPLRRAKVAALVEPLLEPLAHELIDDFADRGTADLVAEFTTRYPVLVISRLLGLPNADEATVHR
WARDLFHFPLDPDAARRASREFTAYVTPVLAERRRAPGDDLISLLVTTSAEGEHLTDEQVLSFLRLLFPAGADTTMLGLG
NILSALLTHPEQLARVAADPDEWVRWAVWEGLRWEPPVGLLPRACPEAVEWHGISIPAGTPMIFAITAAHRDPGHYPDPD
RFDITRQATAMLSFGQGPHSCPGNWLALAELTTALGALLARLPGLRLRPGAADRARVTSQVGTALRGPNALAVEWDR
>Mature_396_residues
STPTSLDGLDFAFHDLPDLHATLADLRRRAPWATVPFAGSRAILLLTHDLVAAAFKDEVTFPAAVTYRLTTGPVLGHTLQ
CMQGREHRIARGIATPPLRRAKVAALVEPLLEPLAHELIDDFADRGTADLVAEFTTRYPVLVISRLLGLPNADEATVHRW
ARDLFHFPLDPDAARRASREFTAYVTPVLAERRRAPGDDLISLLVTTSAEGEHLTDEQVLSFLRLLFPAGADTTMLGLGN
ILSALLTHPEQLARVAADPDEWVRWAVWEGLRWEPPVGLLPRACPEAVEWHGISIPAGTPMIFAITAAHRDPGHYPDPDR
FDITRQATAMLSFGQGPHSCPGNWLALAELTTALGALLARLPGLRLRPGAADRARVTSQVGTALRGPNALAVEWDR

Specific function: Unknown

COG id: COG2124

COG function: function code Q; Cytochrome P450

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

Organism=Homo sapiens, GI119220562, Length=245, Percent_Identity=27.7551020408163, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI158138530, Length=293, Percent_Identity=25.5972696245734, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI13435391, Length=245, Percent_Identity=26.9387755102041, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI150036266, Length=242, Percent_Identity=26.8595041322314, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI6005737, Length=248, Percent_Identity=27.0161290322581, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24642101, Length=189, Percent_Identity=30.1587301587302, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17933518, Length=207, Percent_Identity=26.5700483091787, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR002397
- InterPro:   IPR017972 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: NA

Molecular weight: Translated: 43343; Mature: 43212

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPTSLDGLDFAFHDLPDLHATLADLRRRAPWATVPFAGSRAILLLTHDLVAAAFKDEV
CCCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHCCC
TFPAAVTYRLTTGPVLGHTLQCMQGREHRIARGIATPPLRRAKVAALVEPLLEPLAHELI
CCCEEEEEEEECCCHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
DDFADRGTADLVAEFTTRYPVLVISRLLGLPNADEATVHRWARDLFHFPLDPDAARRASR
HHHHCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
EFTAYVTPVLAERRRAPGDDLISLLVTTSAEGEHLTDEQVLSFLRLLFPAGADTTMLGLG
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHH
NILSALLTHPEQLARVAADPDEWVRWAVWEGLRWEPPVGLLPRACPEAVEWHGISIPAGT
HHHHHHHHCHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCEECCCCC
PMIFAITAAHRDPGHYPDPDRFDITRQATAMLSFGQGPHSCPGNWLALAELTTALGALLA
CEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
RLPGLRLRPGAADRARVTSQVGTALRGPNALAVEWDR
HCCCCEECCCCCHHHHHHHHHHHHHCCCCEEEEEECC
>Mature Secondary Structure 
STPTSLDGLDFAFHDLPDLHATLADLRRRAPWATVPFAGSRAILLLTHDLVAAAFKDEV
CCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHCCC
TFPAAVTYRLTTGPVLGHTLQCMQGREHRIARGIATPPLRRAKVAALVEPLLEPLAHELI
CCCEEEEEEEECCCHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
DDFADRGTADLVAEFTTRYPVLVISRLLGLPNADEATVHRWARDLFHFPLDPDAARRASR
HHHHCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
EFTAYVTPVLAERRRAPGDDLISLLVTTSAEGEHLTDEQVLSFLRLLFPAGADTTMLGLG
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHH
NILSALLTHPEQLARVAADPDEWVRWAVWEGLRWEPPVGLLPRACPEAVEWHGISIPAGT
HHHHHHHHCHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCEECCCCC
PMIFAITAAHRDPGHYPDPDRFDITRQATAMLSFGQGPHSCPGNWLALAELTTALGALLA
CEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
RLPGLRLRPGAADRARVTSQVGTALRGPNALAVEWDR
HCCCCEECCCCCHHHHHHHHHHHHHCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]