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The map label for this gene is ktrA

Identifier: 54020584

GI number: 54020584

Start: 710341

End: 711036

Strand: Reverse

Name: ktrA

Synonym: mhp562

Alternate gene names: 54020584

Gene position: 711036-710341 (Counterclockwise)

Preceding gene: 54020585

Following gene: 54020583

Centisome position: 79.64

GC content: 34.05

Gene sequence:

>696_bases
ATGAAACGAGCAAATATCTGTATAATTGGAGCAGGGCGACTAGGAAGAGCGGCAATTTCCCAGCTTGCTGAATCAGGTCA
TAATGTGATTGTGATTGATAAGAAAGCGGAAAATCTTAAATTTATTCGTGAATTTGCGACTATAGAACCCATTATTATGG
ATGCAAGTGATATTAACGCGATGCGAAATGAGGTTGGGCTTGAAGATATTGACACGATTATAGTAGCAACTTCAGATAAT
ATTGAAATTATTGCAACTTTATTAGAATTACAGGCCGAAATTAATTTATTTAATAATTTAAAAATAGCGGCCCGGGCAGT
AAATAAAAGGCACGCGCGGGTTTTAAAACAGATTGGCGTTGACTGAATTATTAGCCCTGAAGAAGAAGCGGGAATTAAAA
TGGCACTTCTGACGGTGGATAAAAATTTTCTTAACTATGCCGATAGTCTTAAAGAAATTGCAAATGGAGTTTTTGCCGGA
AGTGTTAATGTAAGATCGCCTCATTATATAAATAAAAGTATTAGAAATGCGAATTTACGTCAATTTAATGTTAATGTGGT
TTTAATTAAAAGAAATAAAGAAACTTTCTTGCCAGCGGCCGAGACAATAATTCAGTTAAATGATGAAATTACGATTATTG
GAAAAATCGGTGATGTTGCGACAGTTTTACAAAAGTTAGAATCAATCAAAAAGTAA

Upstream 100 bases:

>100_bases
TTGATTGAGTTAGATAAAAAATTTTATTTATAAAATTTTAAATTTATTTTTTTTGGATAATTTTAAAAATTTTTTCAATT
TTGGTCTACAATTTAGTCAA

Downstream 100 bases:

>100_bases
AAAAGTGTATGTTTTTATAGGCTTTTTGTAAATTGTTTGATTAAATTAGCAAGGATTTTACAAATTTAAGGCAATTTTTT
CTAAAGCCTTTTTGTTGATG

Product: potassium uptake protein

Products: NA

Alternate protein names: K(+)-uptake protein ktrA [H]

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MKRANICIIGAGRLGRAAISQLAESGHNVIVIDKKAENLKFIREFATIEPIIMDASDINAMRNEVGLEDIDTIIVATSDN
IEIIATLLELQAEINLFNNLKIAARAVNKRHARVLKQIGVDWIISPEEEAGIKMALLTVDKNFLNYADSLKEIANGVFAG
SVNVRSPHYINKSIRNANLRQFNVNVVLIKRNKETFLPAAETIIQLNDEITIIGKIGDVATVLQKLESIKK

Sequences:

>Translated_231_residues
MKRANICIIGAGRLGRAAISQLAESGHNVIVIDKKAENLKFIREFATIEPIIMDASDINAMRNEVGLEDIDTIIVATSDN
IEIIATLLELQAEINLFNNLKIAARAVNKRHARVLKQIGVD*IISPEEEAGIKMALLTVDKNFLNYADSLKEIANGVFAG
SVNVRSPHYINKSIRNANLRQFNVNVVLIKRNKETFLPAAETIIQLNDEITIIGKIGDVATVLQKLESIKK
>Mature_231_residues
MKRANICIIGAGRLGRAAISQLAESGHNVIVIDKKAENLKFIREFATIEPIIMDASDINAMRNEVGLEDIDTIIVATSDN
IEIIATLLELQAEINLFNNLKIAARAVNKRHARVLKQIGVD*IISPEEEAGIKMALLTVDKNFLNYADSLKEIANGVFAG
SVNVRSPHYINKSIRNANLRQFNVNVVLIKRNKETFLPAAETIIQLNDEITIIGKIGDVATVLQKLESIKK

Specific function: Catalytic subunit of the ktrAB potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and ktrCD confer resistance to both suddenly imposed and prolonged osmotic stress [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 25346; Mature: 25346

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRANICIIGAGRLGRAAISQLAESGHNVIVIDKKAENLKFIREFATIEPIIMDASDINA
CCCCCEEEEECCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCEEECCHHHHH
MRNEVGLEDIDTIIVATSDNIEIIATLLELQAEINLFNNLKIAARAVNKRHARVLKQIGV
HHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
DIISPEEEAGIKMALLTVDKNFLNYADSLKEIANGVFAGSVNVRSPHYINKSIRNANLRQ
EEECCCCCCCEEEEEEEECHHHHHHHHHHHHHHCCEEECEEECCCCHHHHHHHCCCCCEE
FNVNVVLIKRNKETFLPAAETIIQLNDEITIIGKIGDVATVLQKLESIKK
EEEEEEEEECCCCCCCHHHHHHEEECCCEEEEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKRANICIIGAGRLGRAAISQLAESGHNVIVIDKKAENLKFIREFATIEPIIMDASDINA
CCCCCEEEEECCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCEEECCHHHHH
MRNEVGLEDIDTIIVATSDNIEIIATLLELQAEINLFNNLKIAARAVNKRHARVLKQIGV
HHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
DIISPEEEAGIKMALLTVDKNFLNYADSLKEIANGVFAGSVNVRSPHYINKSIRNANLRQ
EEECCCCCCCEEEEEEEECHHHHHHHHHHHHHHCCEEECEEECCCCHHHHHHHCCCCCEE
FNVNVVLIKRNKETFLPAAETIIQLNDEITIIGKIGDVATVLQKLESIKK
EEEEEEEEECCCCCCCHHHHHHEEECCCEEEEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 12086676 [H]