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The map label for this gene is potA

Identifier: 54020583

GI number: 54020583

Start: 706234

End: 707568

Strand: Reverse

Name: potA

Synonym: mhp559

Alternate gene names: 54020583

Gene position: 707568-706234 (Counterclockwise)

Preceding gene: 54020584

Following gene: 54020582

Centisome position: 79.26

GC content: 30.34

Gene sequence:

>1335_bases
ATGAAAAATATTGAAAAAAGTGAAATAATTATCTCCCTTGTTGATGTTGATAAAGAATTTGGTGATAAAAAAGTTTTAGA
TCAAATAAATTTGGACATTAAACGAGGAGATTTTGTCACACTTTTAGGGCCCTCAGGGTCCGGGAAGACAACAATTTTAC
GTTTAATTGGTGGTTTTGAATGAACTACTCGCGGCGAAATCAAATTTAATGGCATCGATATAAAAGACGTTCCGGCACAT
AAACGTGATACAGCTACAATTTTTCAAGATTATGCACTTTTTCCACATTTATCAGTTCGTGGAAATATTGAATTTGGTCT
TAAATTAAAAAGAATTAAAAAAAAGGCAGAAGAAATTCCGGATGTAGTCTGGAAAAAATTTGAGCACTTAAAGAAAAAAT
GACAGGATAAGCAAAAGCGAAAGATTAAAGAGTTAAAAATTTTACAGGCTCATTTAGAAAAACTGCTTGAAAATCCACAG
TTAGATATTAAAAAACGTAAAAAATTACAGGATAAATTAGATGATTCTGATTTTAGATATTCAAATTGAGAAAATTATCT
AACATCCAAATCAGAAAGTTTTAAAAAAAAGTACCTAACCCGAAGAATCACAAAACAGGAAATTAATAAAGAAATTACCG
ATATTATTGACCTTGTTGGTCTAACTGGAAATGAAAATCGAGCAATTTCGGAATTATCAGGGGGAATGAAACAACGGGTA
GCACTTGCAAGATCGCTTGTAATTGAGCCTGAAATTGTCCTACTTGATGAACCTTTATCAGCTTTAGATACAAAAATTCG
GCAAAAAATGCAAGTTTTTCTAAAAAAAATTCAACAAAAACTTGGCCTAACTTTTATTTTTGTTACTCATGATCAAGATG
AAGCCTTGCAATTATCAGATAAAATCGCCATAATCCGTAATGGAAAAATCGCCCAATACGATGAACCAAAACAAATTTAT
GACTATCCAGTTAATAAATGGGTGGCTAATTTTATTGGTGATTCTAATTTTTTTCAGGCAAAATACATTAAAAAAAATCA
AGTCGAAATTCTTGGTCTTAAATTATATACAATTCATGATGAGTTTATCCCAGGCCAAAAATTAGATTGCCTGATTCGCC
CAGAGGATATCGATATTGACCTAAATTCAGGCTATTTTAAAGGAAAAGTTATCCAAAATATTTATAAAGGTTCATATTAT
TCACTTGATATCAAAGTAGAAAATACAATAATTAATGTCGAAACTAACGATTTTTATGACCTCGAGACTCAAGTTTTTAT
AAAATGAGATGATGATGCTATTCATTTAATGGAGATGGAAAATGCTGAAATTTAA

Upstream 100 bases:

>100_bases
AAAGATGAAGTTTTCATATTTTTTTTTAAGAATAAAATATTTTTTTATTCAAATTAGAAGTTATTTTTATTTTATCTAAT
TTAAGGGGAAAATTTAAATA

Downstream 100 bases:

>100_bases
TTTTTTTGAAAATTTTTGAAAAAATTTCAAAAAAAGTTTAAACCCCCGCATCAGTCTTGTAATTCCCTATGTAATTTTTG
CCCTGATTTTTGTAATAATT

Product: spermidine/putrescine transport ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MKNIEKSEIIISLVDVDKEFGDKKVLDQINLDIKRGDFVTLLGPSGSGKTTILRLIGGFEWTTRGEIKFNGIDIKDVPAH
KRDTATIFQDYALFPHLSVRGNIEFGLKLKRIKKKAEEIPDVVWKKFEHLKKKWQDKQKRKIKELKILQAHLEKLLENPQ
LDIKKRKKLQDKLDDSDFRYSNWENYLTSKSESFKKKYLTRRITKQEINKEITDIIDLVGLTGNENRAISELSGGMKQRV
ALARSLVIEPEIVLLDEPLSALDTKIRQKMQVFLKKIQQKLGLTFIFVTHDQDEALQLSDKIAIIRNGKIAQYDEPKQIY
DYPVNKWVANFIGDSNFFQAKYIKKNQVEILGLKLYTIHDEFIPGQKLDCLIRPEDIDIDLNSGYFKGKVIQNIYKGSYY
SLDIKVENTIINVETNDFYDLETQVFIKWDDDAIHLMEMENAEI

Sequences:

>Translated_444_residues
MKNIEKSEIIISLVDVDKEFGDKKVLDQINLDIKRGDFVTLLGPSGSGKTTILRLIGGFE*TTRGEIKFNGIDIKDVPAH
KRDTATIFQDYALFPHLSVRGNIEFGLKLKRIKKKAEEIPDVVWKKFEHLKKK*QDKQKRKIKELKILQAHLEKLLENPQ
LDIKKRKKLQDKLDDSDFRYSN*ENYLTSKSESFKKKYLTRRITKQEINKEITDIIDLVGLTGNENRAISELSGGMKQRV
ALARSLVIEPEIVLLDEPLSALDTKIRQKMQVFLKKIQQKLGLTFIFVTHDQDEALQLSDKIAIIRNGKIAQYDEPKQIY
DYPVNKWVANFIGDSNFFQAKYIKKNQVEILGLKLYTIHDEFIPGQKLDCLIRPEDIDIDLNSGYFKGKVIQNIYKGSYY
SLDIKVENTIINVETNDFYDLETQVFIK*DDDAIHLMEMENAEI
>Mature_444_residues
MKNIEKSEIIISLVDVDKEFGDKKVLDQINLDIKRGDFVTLLGPSGSGKTTILRLIGGFE*TTRGEIKFNGIDIKDVPAH
KRDTATIFQDYALFPHLSVRGNIEFGLKLKRIKKKAEEIPDVVWKKFEHLKKK*QDKQKRKIKELKILQAHLEKLLENPQ
LDIKKRKKLQDKLDDSDFRYSN*ENYLTSKSESFKKKYLTRRITKQEINKEITDIIDLVGLTGNENRAISELSGGMKQRV
ALARSLVIEPEIVLLDEPLSALDTKIRQKMQVFLKKIQQKLGLTFIFVTHDQDEALQLSDKIAIIRNGKIAQYDEPKQIY
DYPVNKWVANFIGDSNFFQAKYIKKNQVEILGLKLYTIHDEFIPGQKLDCLIRPEDIDIDLNSGYFKGKVIQNIYKGSYY
SLDIKVENTIINVETNDFYDLETQVFIK*DDDAIHLMEMENAEI

Specific function: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system [H]

COG id: COG3842

COG function: function code E; ABC-type spermidine/putrescine transport systems, ATPase components

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI31657092, Length=107, Percent_Identity=33.6448598130841, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI105990541, Length=107, Percent_Identity=34.5794392523364, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI42741659, Length=90, Percent_Identity=40, Blast_Score=66, Evalue=8e-11,
Organism=Homo sapiens, GI9961252, Length=90, Percent_Identity=38.8888888888889, Blast_Score=65, Evalue=9e-11,
Organism=Homo sapiens, GI4505771, Length=90, Percent_Identity=38.8888888888889, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1787370, Length=226, Percent_Identity=40.2654867256637, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1787712, Length=209, Percent_Identity=38.755980861244, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1788761, Length=236, Percent_Identity=31.7796610169492, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI87081791, Length=139, Percent_Identity=42.4460431654676, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI87081709, Length=220, Percent_Identity=31.3636363636364, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1790467, Length=187, Percent_Identity=37.4331550802139, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1789032, Length=146, Percent_Identity=42.4657534246575, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI87082267, Length=186, Percent_Identity=33.8709677419355, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1788450, Length=135, Percent_Identity=36.2962962962963, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1786398, Length=128, Percent_Identity=36.71875, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1790544, Length=312, Percent_Identity=24.3589743589744, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1787500, Length=161, Percent_Identity=29.8136645962733, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1787164, Length=92, Percent_Identity=48.9130434782609, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789962, Length=199, Percent_Identity=26.6331658291457, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1786563, Length=90, Percent_Identity=43.3333333333333, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788506, Length=127, Percent_Identity=29.1338582677165, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787029, Length=147, Percent_Identity=30.6122448979592, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1789864, Length=315, Percent_Identity=22.2222222222222, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1787758, Length=103, Percent_Identity=31.0679611650485, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786253, Length=85, Percent_Identity=43.5294117647059, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789672, Length=120, Percent_Identity=34.1666666666667, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1788644, Length=134, Percent_Identity=30.5970149253731, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI48994883, Length=176, Percent_Identity=23.8636363636364, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1788225, Length=128, Percent_Identity=31.25, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1786319, Length=92, Percent_Identity=41.304347826087, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786872, Length=121, Percent_Identity=33.8842975206612, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI145693107, Length=108, Percent_Identity=28.7037037037037, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI87081834, Length=104, Percent_Identity=38.4615384615385, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789891, Length=82, Percent_Identity=39.0243902439024, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1790162, Length=102, Percent_Identity=32.3529411764706, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI48994997, Length=94, Percent_Identity=31.9148936170213, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI87081782, Length=108, Percent_Identity=36.1111111111111, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1789963, Length=117, Percent_Identity=28.2051282051282, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789586, Length=107, Percent_Identity=35.5140186915888, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787547, Length=125, Percent_Identity=25.6, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787759, Length=102, Percent_Identity=28.4313725490196, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1787089, Length=93, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786345, Length=110, Percent_Identity=32.7272727272727, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789890, Length=119, Percent_Identity=30.2521008403361, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI48995001, Length=113, Percent_Identity=28.3185840707965, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786803, Length=115, Percent_Identity=30.4347826086957, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787182, Length=107, Percent_Identity=32.7102803738318, Blast_Score=62, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI71983516, Length=120, Percent_Identity=31.6666666666667, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71983510, Length=120, Percent_Identity=31.6666666666667, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71983523, Length=120, Percent_Identity=31.6666666666667, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17565586, Length=119, Percent_Identity=31.9327731092437, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI25146777, Length=90, Percent_Identity=42.2222222222222, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI115533608, Length=115, Percent_Identity=33.0434782608696, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17569143, Length=91, Percent_Identity=45.0549450549451, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17569145, Length=91, Percent_Identity=43.956043956044, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI221500365, Length=105, Percent_Identity=34.2857142857143, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI116007184, Length=105, Percent_Identity=34.2857142857143, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24643674, Length=105, Percent_Identity=34.2857142857143, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI85726357, Length=83, Percent_Identity=43.3734939759036, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR008995
- InterPro:   IPR017879
- InterPro:   IPR013611 [H]

Pfam domain/function: PF00005 ABC_tran; PF08402 TOBE_2 [H]

EC number: =3.6.3.31 [H]

Molecular weight: Translated: 50873; Mature: 50873

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNIEKSEIIISLVDVDKEFGDKKVLDQINLDIKRGDFVTLLGPSGSGKTTILRLIGGFE
CCCCCCCCEEEEEEECCHHHCCHHHHHHHCCEEECCCEEEEECCCCCCCCEEEEECCCCC
TTRGEIKFNGIDIKDVPAHKRDTATIFQDYALFPHLSVRGNIEFGLKLKRIKKKAEEIPD
CCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCEECEEHHHHHHHHHHHHH
VVWKKFEHLKKKQDKQKRKIKELKILQAHLEKLLENPQLDIKKRKKLQDKLDDSDFRYSN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEECC
ENYLTSKSESFKKKYLTRRITKQEINKEITDIIDLVGLTGNENRAISELSGGMKQRVALA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHH
RSLVIEPEIVLLDEPLSALDTKIRQKMQVFLKKIQQKLGLTFIFVTHDQDEALQLSDKIA
HHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHCCCEE
IIRNGKIAQYDEPKQIYDYPVNKWVANFIGDSNFFQAKYIKKNQVEILGLKLYTIHDEFI
EEECCEECCCCCCHHHHCCCHHHHHHHHCCCCCCEEEEEECCCCEEEEEEEEEEEECCCC
PGQKLDCLIRPEDIDIDLNSGYFKGKVIQNIYKGSYYSLDIKVENTIINVETNDFYDLET
CCCCCEEEECCCCCEEECCCCEECHHHHHHHHCCCEEEEEEEEEEEEEEEECCCEEECEE
QVFIKDDDAIHLMEMENAEI
EEEEECCCCEEEEECCCCCC
>Mature Secondary Structure
MKNIEKSEIIISLVDVDKEFGDKKVLDQINLDIKRGDFVTLLGPSGSGKTTILRLIGGFE
CCCCCCCCEEEEEEECCHHHCCHHHHHHHCCEEECCCEEEEECCCCCCCCEEEEECCCCC
TTRGEIKFNGIDIKDVPAHKRDTATIFQDYALFPHLSVRGNIEFGLKLKRIKKKAEEIPD
CCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCEECEEHHHHHHHHHHHHH
VVWKKFEHLKKKQDKQKRKIKELKILQAHLEKLLENPQLDIKKRKKLQDKLDDSDFRYSN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEECC
ENYLTSKSESFKKKYLTRRITKQEINKEITDIIDLVGLTGNENRAISELSGGMKQRVALA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHH
RSLVIEPEIVLLDEPLSALDTKIRQKMQVFLKKIQQKLGLTFIFVTHDQDEALQLSDKIA
HHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHCCCEE
IIRNGKIAQYDEPKQIYDYPVNKWVANFIGDSNFFQAKYIKKNQVEILGLKLYTIHDEFI
EEECCEECCCCCCHHHHCCCHHHHHHHHCCCCCCEEEEEECCCCEEEEEEEEEEEECCCC
PGQKLDCLIRPEDIDIDLNSGYFKGKVIQNIYKGSYYSLDIKVENTIINVETNDFYDLET
CCCCCEEEECCCCCEEECCCCEECHHHHHHHHCCCEEEEEEEEEEEEEEEECCCEEECEE
QVFIKDDDAIHLMEMENAEI
EEEEECCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA