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The map label for this gene is atpD

Identifier: 54020006

GI number: 54020006

Start: 65143

End: 66558

Strand: Direct

Name: atpD

Synonym: mhp055

Alternate gene names: 54020006

Gene position: 65143-66558 (Clockwise)

Preceding gene: 54020005

Following gene: 54020007

Centisome position: 7.3

GC content: 37.08

Gene sequence:

>1416_bases
ATGGAAAAACAAGAAAATGTTGGTCATATTGTACAAATTTTTGGCCCTGTCATTGATGTTCAGTTCCCAAACGAACATAT
GCCGGCGATTCTTTCAGCTCTTGAGGTTAAAATTAACGATGAGAGTATAATTTTTGAGGTCGCACAGCATTTAGGTGAAG
GAATTGTTAGGGCAATCGCAATGTCAATGACTTATAATTTATCAAAAGGACTTGAGGTTTATGATACTGGTTCACAAATT
TCAGTTCCTGTTGGAAAACAAGTACTTTCTCGAATGTTTAATGTTTTAGGTCAACCAATCGATGGCGGAAAACCACTTGA
TTCATTTATAAAAAATCCTATTCATGCAAATGCGCCGACATATTTAGAGCAAAAAGCAACTAGCGAAATTTTAGTTACTG
GCATAAAAGTAATTGATCTTTTAATACCATTTATAAAAGGCGGGAAAATCGGACTTTTTGGCGGGGCAGGTGTTGGCAAA
ACTGTTTTAGTTCAAGAATTAATCAATAATATCGCTTCAAAACATGGAGGTCTTTCGGTTTTTGCAGGAGTCGGCGAAAG
ATCGCGCGAAGGAAATGATCTTTATTTTGAAATGAAAAAGGCCGGTGTTCTAGATAAAACGGCGCTTGTTTTTGGACAAA
TGAATGAACCTCCTGGAGCAAGAATGCGAGTTGCGCTCTCAGCACTAACGATGGCAGAGTATTTTCGTGACTATGAAAAT
CAGGATGTTCTACTTTTTATTGATAATATCTTTCGGTTTACTCAGGCAGGCTCAGAAGTTTCAACTTTATTAGGAAGAAT
TCCTTCAACAGTAGGATACCAACCAACATTATCCACTGAAATGGGTCAGTTACAAGAGCGAATTACATCAACAATTCGCG
GTTCAATAACCTCGGTTCAAGCGGTTTATGTCCCAGCCGATGATATCACTGATCCCGCGCCAGCAACAACTTTTTCTCAT
CTTGATGCAAAAACAGTTTTAGATCGAGGCATTGCTGCTTTAGGGATTTATCCAGCAGTAGATCCGCTGGCTTCATCATC
GCGGGCACTTGAACCAAATATTGTCGGTAAAAAACATTATCTAGTTGCCAAAAAAGTTGTTCAAATTTTGCAAAGATTTA
AGGAATTACAAGATATTATTGCGATTTTAGGGGTCGATGAACTAAGTGAATCTGATAAACAAGTCGTTGCCCGTGCGCGA
AGAATTCGAAATTTTTTATCACAACCATTCTTCGTAGCGCAGAAATTTTCCGGAATTCAAGGGCAATTTATAAAAATTCA
AGATACGGTTAATAATTTTGATGAACTTTTATCAGGAAAATATGATAATATCCCTGAAGAAGCATTTTTATATGTAGGGA
CAATTGATCAAGCACTTGAAAAAGCAAAAAAAATGGGTTGAAGTGAAAAAAATTAG

Upstream 100 bases:

>100_bases
ATAAGTTAGAAACAGAAATAAATTCAAGTCGTCAAGCAATGATTACACAAGAAATTATTGAGATTATTAGTGGTAAAATG
TAGAAAAAGTAGGTAAATTT

Downstream 100 bases:

>100_bases
TCTTAAAATCCTTACTCCAAAAGGAGTTTTTTTAGAATCAAGTCCTTATTCAGTGACAGTGAAAACAAAACTAGGTTACC
GAATTGCCCAGTATGGAATT

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta [H]

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MEKQENVGHIVQIFGPVIDVQFPNEHMPAILSALEVKINDESIIFEVAQHLGEGIVRAIAMSMTYNLSKGLEVYDTGSQI
SVPVGKQVLSRMFNVLGQPIDGGKPLDSFIKNPIHANAPTYLEQKATSEILVTGIKVIDLLIPFIKGGKIGLFGGAGVGK
TVLVQELINNIASKHGGLSVFAGVGERSREGNDLYFEMKKAGVLDKTALVFGQMNEPPGARMRVALSALTMAEYFRDYEN
QDVLLFIDNIFRFTQAGSEVSTLLGRIPSTVGYQPTLSTEMGQLQERITSTIRGSITSVQAVYVPADDITDPAPATTFSH
LDAKTVLDRGIAALGIYPAVDPLASSSRALEPNIVGKKHYLVAKKVVQILQRFKELQDIIAILGVDELSESDKQVVARAR
RIRNFLSQPFFVAQKFSGIQGQFIKIQDTVNNFDELLSGKYDNIPEEAFLYVGTIDQALEKAKKMGWSEKN

Sequences:

>Translated_471_residues
MEKQENVGHIVQIFGPVIDVQFPNEHMPAILSALEVKINDESIIFEVAQHLGEGIVRAIAMSMTYNLSKGLEVYDTGSQI
SVPVGKQVLSRMFNVLGQPIDGGKPLDSFIKNPIHANAPTYLEQKATSEILVTGIKVIDLLIPFIKGGKIGLFGGAGVGK
TVLVQELINNIASKHGGLSVFAGVGERSREGNDLYFEMKKAGVLDKTALVFGQMNEPPGARMRVALSALTMAEYFRDYEN
QDVLLFIDNIFRFTQAGSEVSTLLGRIPSTVGYQPTLSTEMGQLQERITSTIRGSITSVQAVYVPADDITDPAPATTFSH
LDAKTVLDRGIAALGIYPAVDPLASSSRALEPNIVGKKHYLVAKKVVQILQRFKELQDIIAILGVDELSESDKQVVARAR
RIRNFLSQPFFVAQKFSGIQGQFIKIQDTVNNFDELLSGKYDNIPEEAFLYVGTIDQALEKAKKMG*SEKN
>Mature_471_residues
MEKQENVGHIVQIFGPVIDVQFPNEHMPAILSALEVKINDESIIFEVAQHLGEGIVRAIAMSMTYNLSKGLEVYDTGSQI
SVPVGKQVLSRMFNVLGQPIDGGKPLDSFIKNPIHANAPTYLEQKATSEILVTGIKVIDLLIPFIKGGKIGLFGGAGVGK
TVLVQELINNIASKHGGLSVFAGVGERSREGNDLYFEMKKAGVLDKTALVFGQMNEPPGARMRVALSALTMAEYFRDYEN
QDVLLFIDNIFRFTQAGSEVSTLLGRIPSTVGYQPTLSTEMGQLQERITSTIRGSITSVQAVYVPADDITDPAPATTFSH
LDAKTVLDRGIAALGIYPAVDPLASSSRALEPNIVGKKHYLVAKKVVQILQRFKELQDIIAILGVDELSESDKQVVARAR
RIRNFLSQPFFVAQKFSGIQGQFIKIQDTVNNFDELLSGKYDNIPEEAFLYVGTIDQALEKAKKMG*SEKN

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits [H]

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=469, Percent_Identity=63.3262260127932, Blast_Score=608, Evalue=1e-174,
Organism=Homo sapiens, GI19913424, Length=312, Percent_Identity=29.8076923076923, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI19913428, Length=356, Percent_Identity=25.8426966292135, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI19913426, Length=361, Percent_Identity=25.207756232687, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI50345984, Length=379, Percent_Identity=25.065963060686, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI4757810, Length=379, Percent_Identity=25.065963060686, Blast_Score=94, Evalue=3e-19,
Organism=Escherichia coli, GI1790170, Length=458, Percent_Identity=61.7903930131004, Blast_Score=580, Evalue=1e-167,
Organism=Escherichia coli, GI1788251, Length=313, Percent_Identity=30.3514376996805, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1790172, Length=393, Percent_Identity=25.4452926208651, Blast_Score=119, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI25144756, Length=467, Percent_Identity=62.3126338329765, Blast_Score=592, Evalue=1e-169,
Organism=Caenorhabditis elegans, GI17565854, Length=322, Percent_Identity=31.055900621118, Blast_Score=122, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17510931, Length=359, Percent_Identity=25.9052924791086, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17570191, Length=359, Percent_Identity=25.6267409470752, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71988080, Length=373, Percent_Identity=25.201072386059, Blast_Score=101, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI71988063, Length=373, Percent_Identity=25.201072386059, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71988074, Length=351, Percent_Identity=24.5014245014245, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322581, Length=454, Percent_Identity=65.4185022026432, Blast_Score=613, Evalue=1e-176,
Organism=Saccharomyces cerevisiae, GI6319603, Length=340, Percent_Identity=27.0588235294118, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6319370, Length=377, Percent_Identity=25.9946949602122, Blast_Score=102, Evalue=9e-23,
Organism=Saccharomyces cerevisiae, GI6320016, Length=281, Percent_Identity=26.6903914590747, Blast_Score=84, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24638766, Length=467, Percent_Identity=63.5974304068523, Blast_Score=599, Evalue=1e-171,
Organism=Drosophila melanogaster, GI28574560, Length=474, Percent_Identity=60.9704641350211, Blast_Score=558, Evalue=1e-159,
Organism=Drosophila melanogaster, GI24583988, Length=325, Percent_Identity=28.9230769230769, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24583986, Length=325, Percent_Identity=28.9230769230769, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24583984, Length=325, Percent_Identity=28.9230769230769, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24583992, Length=383, Percent_Identity=27.6762402088773, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI20129479, Length=344, Percent_Identity=27.6162790697674, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI281361666, Length=357, Percent_Identity=26.6106442577031, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24646341, Length=357, Percent_Identity=26.6106442577031, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI17136796, Length=357, Percent_Identity=26.6106442577031, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24658560, Length=405, Percent_Identity=24.1975308641975, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24638768, Length=91, Percent_Identity=49.4505494505495, Blast_Score=89, Evalue=8e-18,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 51356; Mature: 51356

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKQENVGHIVQIFGPVIDVQFPNEHMPAILSALEVKINDESIIFEVAQHLGEGIVRAIA
CCCCCHHHHHHHHHHCEEEEECCCCHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHH
MSMTYNLSKGLEVYDTGSQISVPVGKQVLSRMFNVLGQPIDGGKPLDSFIKNPIHANAPT
HHHHHHHCCCCEEEECCCEEECCHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCH
YLEQKATSEILVTGIKVIDLLIPFIKGGKIGLFGGAGVGKTVLVQELINNIASKHGGLSV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCEEE
FAGVGERSREGNDLYFEMKKAGVLDKTALVFGQMNEPPGARMRVALSALTMAEYFRDYEN
EECCCCCCCCCCCEEEEEHHCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
QDVLLFIDNIFRFTQAGSEVSTLLGRIPSTVGYQPTLSTEMGQLQERITSTIRGSITSVQ
CCEEEEHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEE
AVYVPADDITDPAPATTFSHLDAKTVLDRGIAALGIYPAVDPLASSSRALEPNIVGKKHY
EEEECCCCCCCCCCCCHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCCCCCCCCHHH
LVAKKVVQILQRFKELQDIIAILGVDELSESDKQVVARARRIRNFLSQPFFVAQKFSGIQ
HHHHHHHHHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCC
GQFIKIQDTVNNFDELLSGKYDNIPEEAFLYVGTIDQALEKAKKMGSEKN
CEEEEEHHHHHHHHHHHCCCCCCCCHHHEEEEHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MEKQENVGHIVQIFGPVIDVQFPNEHMPAILSALEVKINDESIIFEVAQHLGEGIVRAIA
CCCCCHHHHHHHHHHCEEEEECCCCHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHH
MSMTYNLSKGLEVYDTGSQISVPVGKQVLSRMFNVLGQPIDGGKPLDSFIKNPIHANAPT
HHHHHHHCCCCEEEECCCEEECCHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCH
YLEQKATSEILVTGIKVIDLLIPFIKGGKIGLFGGAGVGKTVLVQELINNIASKHGGLSV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCEEE
FAGVGERSREGNDLYFEMKKAGVLDKTALVFGQMNEPPGARMRVALSALTMAEYFRDYEN
EECCCCCCCCCCCEEEEEHHCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
QDVLLFIDNIFRFTQAGSEVSTLLGRIPSTVGYQPTLSTEMGQLQERITSTIRGSITSVQ
CCEEEEHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEE
AVYVPADDITDPAPATTFSHLDAKTVLDRGIAALGIYPAVDPLASSSRALEPNIVGKKHY
EEEECCCCCCCCCCCCHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCCCCCCCCHHH
LVAKKVVQILQRFKELQDIIAILGVDELSESDKQVVARARRIRNFLSQPFFVAQKFSGIQ
HHHHHHHHHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCC
GQFIKIQDTVNNFDELLSGKYDNIPEEAFLYVGTIDQALEKAKKMGSEKN
CEEEEEHHHHHHHHHHHCCCCCCCCHHHEEEEHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA