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The map label for this gene is gap

Identifier: 54019991

GI number: 54019991

Start: 46370

End: 47380

Strand: Direct

Name: gap

Synonym: mhp036

Alternate gene names: 54019991

Gene position: 46370-47380 (Clockwise)

Preceding gene: 54019990

Following gene: 54019992

Centisome position: 5.19

GC content: 34.92

Gene sequence:

>1011_bases
ATGAAAAAAATCGCAATTAATGGCTTTGGACGGATTGGGAGGTTGGCACTTCGTCGTCTTTTTGAAGTTAATGATGAAAA
TTTACAGGTTGTTGCAATTAACGACTTAACAGATGCATCAGTTTTAGCTCATTTATTTAAGTATGATTCCGCCCATGGAA
AGTTTAACGGTGAAGTTGAAGTTTTAAAAGATAACGGAAAAAATTACCTTAAAATTAAAGGTCAAAAAATTCTTGTTTTA
TCTGAAAGAGACCCAAAGTCCTTGCCTTGAGGTCAGCTTGGAATTGATTTGGTTGTTGAATGTACAGGATTTTTTGCTTC
AAAATCAGGAGCTAGTCAACATTTAGAGGCGGGAGCAAAAAAAGTAATAATTTCTGCTCCGGCAGGAAATGATGTTAAAA
CCATTGTTTATAACGTAAATTGTGATACAATTACTGAAGATGATAGAATTTTATCCTCAGCTTCTTGCACTACAAACGCA
CTTGCCCCACTTGTAAATGCGCTTGATAAAGAATTTGGGATAAACCACGGATTTATGACAACAATTCATGCTTATACTGC
AGACCAAAGATTACAGGATGCTCCACATGGGGATTTAAGAAGAGCTCGAGCGGCTGGAGTAAATTTAGTTCCTTCATCAA
CAGGTGCTGCAAAAGCTATTGGACTTGTAGTTCCTTCCCTTACAGGAAAATTGGATGGAATTGCAATTAGAGTCCCAGTG
ATTACAGGATCTTTTGTTGATTTAAGTGTCGAACTTAAATCAAATCCTTCCATAGAAGAAATTAATCAGAAAATGAGAGA
ATATGCAAACGAATCTTTTGCATATTGCGATGAGCCTATCGTTTCCAGCGACATTATTGGAGACAGACATGGATCAATTT
TTGATGCAACATTAACAAAATATATTGAAGCAAATGGCAAAAAACTCTATAAATTATATACATGATATGATAATGAGTAT
TCATTCGTGTCTCAATTTGTAAGGGTTATTAGATATTTTGTGCAAAAATAA

Upstream 100 bases:

>100_bases
GTAAAATTACTAAAAATAATTAAATTTTGTTAATTTTTTGTTTTTTTAGTACCAAAACTCAAAATAGACAAAATTAATAT
AAAAGAAATGGAGATTCGCA

Downstream 100 bases:

>100_bases
CAAAAAGTAAGTAACAAATTTTGTTACCAAAACTACTTAAACTAATATAAAAATCCTTAATAAGAGTTTAAGTTCCTTAT
GAAAGCAAAAATAAGGGGGT

Product: glyceraldehyde 3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MKKIAINGFGRIGRLALRRLFEVNDENLQVVAINDLTDASVLAHLFKYDSAHGKFNGEVEVLKDNGKNYLKIKGQKILVL
SERDPKSLPWGQLGIDLVVECTGFFASKSGASQHLEAGAKKVIISAPAGNDVKTIVYNVNCDTITEDDRILSSASCTTNA
LAPLVNALDKEFGINHGFMTTIHAYTADQRLQDAPHGDLRRARAAGVNLVPSSTGAAKAIGLVVPSLTGKLDGIAIRVPV
ITGSFVDLSVELKSNPSIEEINQKMREYANESFAYCDEPIVSSDIIGDRHGSIFDATLTKYIEANGKKLYKLYTWYDNEY
SFVSQFVRVIRYFVQK

Sequences:

>Translated_336_residues
MKKIAINGFGRIGRLALRRLFEVNDENLQVVAINDLTDASVLAHLFKYDSAHGKFNGEVEVLKDNGKNYLKIKGQKILVL
SERDPKSLP*GQLGIDLVVECTGFFASKSGASQHLEAGAKKVIISAPAGNDVKTIVYNVNCDTITEDDRILSSASCTTNA
LAPLVNALDKEFGINHGFMTTIHAYTADQRLQDAPHGDLRRARAAGVNLVPSSTGAAKAIGLVVPSLTGKLDGIAIRVPV
ITGSFVDLSVELKSNPSIEEINQKMREYANESFAYCDEPIVSSDIIGDRHGSIFDATLTKYIEANGKKLYKLYT*YDNEY
SFVSQFVRVIRYFVQK
>Mature_336_residues
MKKIAINGFGRIGRLALRRLFEVNDENLQVVAINDLTDASVLAHLFKYDSAHGKFNGEVEVLKDNGKNYLKIKGQKILVL
SERDPKSLP*GQLGIDLVVECTGFFASKSGASQHLEAGAKKVIISAPAGNDVKTIVYNVNCDTITEDDRILSSASCTTNA
LAPLVNALDKEFGINHGFMTTIHAYTADQRLQDAPHGDLRRARAAGVNLVPSSTGAAKAIGLVVPSLTGKLDGIAIRVPV
ITGSFVDLSVELKSNPSIEEINQKMREYANESFAYCDEPIVSSDIIGDRHGSIFDATLTKYIEANGKKLYKLYT*YDNEY
SFVSQFVRVIRYFVQK

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=340, Percent_Identity=42.3529411764706, Blast_Score=240, Evalue=2e-63,
Organism=Homo sapiens, GI7657116, Length=344, Percent_Identity=40.9883720930233, Blast_Score=232, Evalue=3e-61,
Organism=Escherichia coli, GI1788079, Length=335, Percent_Identity=42.6865671641791, Blast_Score=251, Evalue=5e-68,
Organism=Escherichia coli, GI1789295, Length=331, Percent_Identity=41.0876132930514, Blast_Score=243, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI17534677, Length=345, Percent_Identity=43.4782608695652, Blast_Score=254, Evalue=7e-68,
Organism=Caenorhabditis elegans, GI17534679, Length=345, Percent_Identity=43.1884057971014, Blast_Score=252, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI32566163, Length=345, Percent_Identity=42.3188405797101, Blast_Score=240, Evalue=9e-64,
Organism=Caenorhabditis elegans, GI17568413, Length=345, Percent_Identity=42.3188405797101, Blast_Score=239, Evalue=1e-63,
Organism=Saccharomyces cerevisiae, GI6322409, Length=340, Percent_Identity=43.2352941176471, Blast_Score=262, Evalue=7e-71,
Organism=Saccharomyces cerevisiae, GI6321631, Length=340, Percent_Identity=41.7647058823529, Blast_Score=259, Evalue=4e-70,
Organism=Saccharomyces cerevisiae, GI6322468, Length=340, Percent_Identity=41.7647058823529, Blast_Score=258, Evalue=1e-69,
Organism=Drosophila melanogaster, GI17933600, Length=341, Percent_Identity=45.4545454545455, Blast_Score=270, Evalue=1e-72,
Organism=Drosophila melanogaster, GI18110149, Length=341, Percent_Identity=45.4545454545455, Blast_Score=270, Evalue=1e-72,
Organism=Drosophila melanogaster, GI85725000, Length=341, Percent_Identity=44.574780058651, Blast_Score=264, Evalue=5e-71,
Organism=Drosophila melanogaster, GI22023983, Length=341, Percent_Identity=44.574780058651, Blast_Score=264, Evalue=5e-71,
Organism=Drosophila melanogaster, GI19922412, Length=337, Percent_Identity=40.6528189910979, Blast_Score=231, Evalue=6e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36485; Mature: 36485

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIAINGFGRIGRLALRRLFEVNDENLQVVAINDLTDASVLAHLFKYDSAHGKFNGEVE
CCEEEECCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCEEE
VLKDNGKNYLKIKGQKILVLSERDPKSLPGQLGIDLVVECTGFFASKSGASQHLEAGAKK
EEECCCCEEEEECCCEEEEEECCCCCCCCCCCCCEEEEEEHHHHCCCCCCHHHHHCCCCE
VIISAPAGNDVKTIVYNVNCDTITEDDRILSSASCTTNALAPLVNALDKEFGINHGFMTT
EEEECCCCCCEEEEEEECCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEE
IHAYTADQRLQDAPHGDLRRARAAGVNLVPSSTGAAKAIGLVVPSLTGKLDGIAIRVPVI
EEEEHHHHHHHCCCCHHHHHHHHCCCEEECCCCCCHHHHHEEECCCCCCCCCEEEEEEEE
TGSFVDLSVELKSNPSIEEINQKMREYANESFAYCDEPIVSSDIIGDRHGSIFDATLTKY
ECCEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
IEANGKKLYKLYTYDNEYSFVSQFVRVIRYFVQK
HHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKIAINGFGRIGRLALRRLFEVNDENLQVVAINDLTDASVLAHLFKYDSAHGKFNGEVE
CCEEEECCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCEEE
VLKDNGKNYLKIKGQKILVLSERDPKSLPGQLGIDLVVECTGFFASKSGASQHLEAGAKK
EEECCCCEEEEECCCEEEEEECCCCCCCCCCCCCEEEEEEHHHHCCCCCCHHHHHCCCCE
VIISAPAGNDVKTIVYNVNCDTITEDDRILSSASCTTNALAPLVNALDKEFGINHGFMTT
EEEECCCCCCEEEEEEECCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEE
IHAYTADQRLQDAPHGDLRRARAAGVNLVPSSTGAAKAIGLVVPSLTGKLDGIAIRVPVI
EEEEHHHHHHHCCCCHHHHHHHHCCCEEECCCCCCHHHHHEEECCCCCCCCCEEEEEEEE
TGSFVDLSVELKSNPSIEEINQKMREYANESFAYCDEPIVSSDIIGDRHGSIFDATLTKY
ECCEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
IEANGKKLYKLYTYDNEYSFVSQFVRVIRYFVQK
HHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7569993; 8253680 [H]