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The map label for this gene is hpmB [H]

Identifier: 53723069

GI number: 53723069

Start: 2768149

End: 2769918

Strand: Reverse

Name: hpmB [H]

Synonym: BPSS2052

Alternate gene names: 53723069

Gene position: 2769918-2768149 (Counterclockwise)

Preceding gene: 53723070

Following gene: 53723068

Centisome position: 87.3

GC content: 62.2

Gene sequence:

>1770_bases
GTGGCATCAATCATGACTATTAAGCGGTTGCCGATCGCGCCATTGTCAGCTTTGGTTATGTTCTCTGCGCAGGCACAACA
GATCCCCACTCCGAACGACCAAGCCGCCGCCGCCCGTGCCAATGCCGAGCAGAATCAGCAGGCGCAACAGCGCCGTGACG
CCCAGCAGCGCGACGCCACCGTGCAAGCGCCGGGCGTGCGCTCGGACGTGCCGCGCCCGGAAGCCTATCCGGTACTGCCG
ACCGAAACACCGTGCTTTCAAATCGACCGCTTCGCACTCGACGTGCCCGACTCGTTACCGGCCGCGTCGAAGGCGCAAGG
CGCGTCAGCCTTGCCGATGGATCGCTTCGCCTTTGCACGCGACTGGCTTGCGCACTACGCCGGCCAATGCATCGGTAAGC
AAGGCGTCGACCTGATCGTTAAGGGGCTGTCGCAAGCCATCCTCGCTCGCGGCTACATCACGACCCGCGTACTCGTGCCC
GAGCAGGATTTGTCCACTGGCGCGTTGAAGCTTGCCCTGATTCCGGGCGTGATCCGCCACGTGCGTTTCGAGGACGAGAA
GTTGCTCGGAACGTGGAAGACCGCTTTCCCGACGCGCGACGGCGACGTGTTGAACCTGCGTGACATTGAGCAAGGGCTTG
AGCAGATGAAGCGCGTGTCAAGCCAGGATGTGTCCATGCGGATCGCACCGGGTGACATGCCCGGCGAAAGCGATGTCGTG
CTCGACGTGAAGCGCGGCAAGCCGTGGACGGTCGTCGCGTCGATCGACAATTCCGGCACGCGCGCGACCGGCAAACTGCA
GGGCAACGTATCGCTTGGCATCGACAACCCGCTGGGCCTGAACGACATTTTCAACGTCGGCTTCAACCAGGATCTGGAAT
TCGGCGATAAGCGCTTCGGTTCGCACGGCTGGAACGCGTTCTATTCGATTCCCTGGGGCTACTGGACCGGCACGCTTTCG
GCGTATACCAGCACGTACTTTCAACCGCTCGCGGCCGTGAATCAGACGTTTGTTGCCAGTGGCAACATGAAGACGGTCGA
CTTCAGGCTCAATCGTGTGCTGACGCGCAGCCGGAACGATGTGTTGGGCGCGCAGGTTCGCTTGACGCGGCGCTTCGGCG
ACAGCTACATCGAAGGCACGACGATACCGTCGTCGCACCAGAACGCGACCTTTCTCGAATTCGGGTTGAACGACCGGCAC
TATTTCGGCTCGTCGCAGTTCGATGGCTCGCTTGCCTATCGTCAGGGGCTCGGCTGGCTCGGCTCGACCGACAGCATGTT
CGCGGCAGAGGGAGGGCAGACGTACCGATTCAAGATGGTCGTGCTCGATGCGAACCTATCGACGCCGTTCGTCATCGGCA
CGCAGCCGTTCAAATACGTGACGACCTTTCATGGTCAGTACACCGGCAACACGGTTTCATATCTCGATAGCGTGACGATC
GGCAGCCGTTATACCGTGCGGGGATTCGACGGTGAAACGCTGCTGGCGGGATCGCGCGGGTTTTACTGGCGCAACGAATT
GCAGGTCCCCGTCGCGCAGACCGGGCTATCGGCCTATGCCGGTCTCGACTACGGTCGGGTCTGGGGACCGGAGCCGGTCG
CGCTGGTCGGCACGCAGCTCGCGGGCGCAGTGATTGGCGTCAAGGGCAGCTTGATGACGCGCTTCGGCGGGTATGGCTAC
GACCTGTTCGCTGGCACACCCGTCTACAAACCGTCCGGGTTTCCCACCGCGCGCGTGACGGTGGGCTTTCAGCTCACGGC
GCAATTCTGA

Upstream 100 bases:

>100_bases
AGTCTCTATATGCACAAGCAAACAGAGATGGTGCACTTCTGATGCGTATGGAAGCACAACTTGGGAATGTGTCGAGAGCA
TACTTAAAAGATTGGGCAAT

Downstream 100 bases:

>100_bases
TGGCGACGAAAGGCCAATCCCATACACGGCTACCTGCCGTCGGGCCCGATACGGAACAGGATCGGGGACTGACGGCCTTC
CTCACCGCGCAAATCGCCCC

Product: activator/secretion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 589; Mature: 588

Protein sequence:

>589_residues
MASIMTIKRLPIAPLSALVMFSAQAQQIPTPNDQAAAARANAEQNQQAQQRRDAQQRDATVQAPGVRSDVPRPEAYPVLP
TETPCFQIDRFALDVPDSLPAASKAQGASALPMDRFAFARDWLAHYAGQCIGKQGVDLIVKGLSQAILARGYITTRVLVP
EQDLSTGALKLALIPGVIRHVRFEDEKLLGTWKTAFPTRDGDVLNLRDIEQGLEQMKRVSSQDVSMRIAPGDMPGESDVV
LDVKRGKPWTVVASIDNSGTRATGKLQGNVSLGIDNPLGLNDIFNVGFNQDLEFGDKRFGSHGWNAFYSIPWGYWTGTLS
AYTSTYFQPLAAVNQTFVASGNMKTVDFRLNRVLTRSRNDVLGAQVRLTRRFGDSYIEGTTIPSSHQNATFLEFGLNDRH
YFGSSQFDGSLAYRQGLGWLGSTDSMFAAEGGQTYRFKMVVLDANLSTPFVIGTQPFKYVTTFHGQYTGNTVSYLDSVTI
GSRYTVRGFDGETLLAGSRGFYWRNELQVPVAQTGLSAYAGLDYGRVWGPEPVALVGTQLAGAVIGVKGSLMTRFGGYGY
DLFAGTPVYKPSGFPTARVTVGFQLTAQF

Sequences:

>Translated_589_residues
MASIMTIKRLPIAPLSALVMFSAQAQQIPTPNDQAAAARANAEQNQQAQQRRDAQQRDATVQAPGVRSDVPRPEAYPVLP
TETPCFQIDRFALDVPDSLPAASKAQGASALPMDRFAFARDWLAHYAGQCIGKQGVDLIVKGLSQAILARGYITTRVLVP
EQDLSTGALKLALIPGVIRHVRFEDEKLLGTWKTAFPTRDGDVLNLRDIEQGLEQMKRVSSQDVSMRIAPGDMPGESDVV
LDVKRGKPWTVVASIDNSGTRATGKLQGNVSLGIDNPLGLNDIFNVGFNQDLEFGDKRFGSHGWNAFYSIPWGYWTGTLS
AYTSTYFQPLAAVNQTFVASGNMKTVDFRLNRVLTRSRNDVLGAQVRLTRRFGDSYIEGTTIPSSHQNATFLEFGLNDRH
YFGSSQFDGSLAYRQGLGWLGSTDSMFAAEGGQTYRFKMVVLDANLSTPFVIGTQPFKYVTTFHGQYTGNTVSYLDSVTI
GSRYTVRGFDGETLLAGSRGFYWRNELQVPVAQTGLSAYAGLDYGRVWGPEPVALVGTQLAGAVIGVKGSLMTRFGGYGY
DLFAGTPVYKPSGFPTARVTVGFQLTAQF
>Mature_588_residues
ASIMTIKRLPIAPLSALVMFSAQAQQIPTPNDQAAAARANAEQNQQAQQRRDAQQRDATVQAPGVRSDVPRPEAYPVLPT
ETPCFQIDRFALDVPDSLPAASKAQGASALPMDRFAFARDWLAHYAGQCIGKQGVDLIVKGLSQAILARGYITTRVLVPE
QDLSTGALKLALIPGVIRHVRFEDEKLLGTWKTAFPTRDGDVLNLRDIEQGLEQMKRVSSQDVSMRIAPGDMPGESDVVL
DVKRGKPWTVVASIDNSGTRATGKLQGNVSLGIDNPLGLNDIFNVGFNQDLEFGDKRFGSHGWNAFYSIPWGYWTGTLSA
YTSTYFQPLAAVNQTFVASGNMKTVDFRLNRVLTRSRNDVLGAQVRLTRRFGDSYIEGTTIPSSHQNATFLEFGLNDRHY
FGSSQFDGSLAYRQGLGWLGSTDSMFAAEGGQTYRFKMVVLDANLSTPFVIGTQPFKYVTTFHGQYTGNTVSYLDSVTIG
SRYTVRGFDGETLLAGSRGFYWRNELQVPVAQTGLSAYAGLDYGRVWGPEPVALVGTQLAGAVIGVKGSLMTRFGGYGYD
LFAGTPVYKPSGFPTARVTVGFQLTAQF

Specific function: Probable member of a two partner secretion pathway (TPS) in which it mediates the secretion of hemolysin [H]

COG id: COG2831

COG function: function code U; Hemolysin activation/secretion protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tpsB (TC 1.B.20) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005565
- InterPro:   IPR013686 [H]

Pfam domain/function: PF08479 POTRA_2; PF03865 ShlB [H]

EC number: NA

Molecular weight: Translated: 64255; Mature: 64124

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASIMTIKRLPIAPLSALVMFSAQAQQIPTPNDQAAAARANAEQNQQAQQRRDAQQRDAT
CCCCEEEECCCCCHHHHHHHHCCHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCE
VQAPGVRSDVPRPEAYPVLPTETPCFQIDRFALDVPDSLPAASKAQGASALPMDRFAFAR
EECCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHH
DWLAHYAGQCIGKQGVDLIVKGLSQAILARGYITTRVLVPEQDLSTGALKLALIPGVIRH
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEHHHHHHHHH
VRFEDEKLLGTWKTAFPTRDGDVLNLRDIEQGLEQMKRVSSQDVSMRIAPGDMPGESDVV
HCCCCCHHEEEHHHCCCCCCCCEEEHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCEE
LDVKRGKPWTVVASIDNSGTRATGKLQGNVSLGIDNPLGLNDIFNVGFNQDLEFGDKRFG
EEEECCCCEEEEEEECCCCCEEEEEEEEEEEECCCCCCCCHHHHHCCCCCCCCCCHHHCC
SHGWNAFYSIPWGYWTGTLSAYTSTYFQPLAAVNQTFVASGNMKTVDFRLNRVLTRSRND
CCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEEHHHHHHHHCCCCC
VLGAQVRLTRRFGDSYIEGTTIPSSHQNATFLEFGLNDRHYFGSSQFDGSLAYRQGLGWL
CCCCEEEEEEHHCCCCCCCCCCCCCCCCCEEEEECCCCCEECCCCCCCCCHHHHHCCCCC
GSTDSMFAAEGGQTYRFKMVVLDANLSTPFVIGTQPFKYVTTFHGQYTGNTVSYLDSVTI
CCCCCEEEECCCCEEEEEEEEEECCCCCCEEECCCCCEEEEEECCCCCCCHHHHHHEEEC
GSRYTVRGFDGETLLAGSRGFYWRNELQVPVAQTGLSAYAGLDYGRVWGPEPVALVGTQL
CCEEEEECCCCCEEEECCCCCEEECCEECCHHHCCCHHHHCCCCCCCCCCCCCEEEHHHH
AGAVIGVKGSLMTRFGGYGYDLFAGTPVYKPSGFPTARVTVGFQLTAQF
HCEEEECCCHHHHHCCCCCEECCCCCCCCCCCCCCEEEEEEEEEEEECC
>Mature Secondary Structure 
ASIMTIKRLPIAPLSALVMFSAQAQQIPTPNDQAAAARANAEQNQQAQQRRDAQQRDAT
CCCEEEECCCCCHHHHHHHHCCHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCE
VQAPGVRSDVPRPEAYPVLPTETPCFQIDRFALDVPDSLPAASKAQGASALPMDRFAFAR
EECCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHH
DWLAHYAGQCIGKQGVDLIVKGLSQAILARGYITTRVLVPEQDLSTGALKLALIPGVIRH
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEHHHHHHHHH
VRFEDEKLLGTWKTAFPTRDGDVLNLRDIEQGLEQMKRVSSQDVSMRIAPGDMPGESDVV
HCCCCCHHEEEHHHCCCCCCCCEEEHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCEE
LDVKRGKPWTVVASIDNSGTRATGKLQGNVSLGIDNPLGLNDIFNVGFNQDLEFGDKRFG
EEEECCCCEEEEEEECCCCCEEEEEEEEEEEECCCCCCCCHHHHHCCCCCCCCCCHHHCC
SHGWNAFYSIPWGYWTGTLSAYTSTYFQPLAAVNQTFVASGNMKTVDFRLNRVLTRSRND
CCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEEHHHHHHHHCCCCC
VLGAQVRLTRRFGDSYIEGTTIPSSHQNATFLEFGLNDRHYFGSSQFDGSLAYRQGLGWL
CCCCEEEEEEHHCCCCCCCCCCCCCCCCCEEEEECCCCCEECCCCCCCCCHHHHHCCCCC
GSTDSMFAAEGGQTYRFKMVVLDANLSTPFVIGTQPFKYVTTFHGQYTGNTVSYLDSVTI
CCCCCEEEECCCCEEEEEEEEEECCCCCCEEECCCCCEEEEEECCCCCCCHHHHHHEEEC
GSRYTVRGFDGETLLAGSRGFYWRNELQVPVAQTGLSAYAGLDYGRVWGPEPVALVGTQL
CCEEEEECCCCCEEEECCCCCEEECCEECCHHHCCCHHHHCCCCCCCCCCCCCEEEHHHH
AGAVIGVKGSLMTRFGGYGYDLFAGTPVYKPSGFPTARVTVGFQLTAQF
HCEEEECCCHHHHHCCCCCEECCCCCCCCCCCCCCEEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2407716 [H]