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The map label for this gene is cyoB

Identifier: 53722917

GI number: 53722917

Start: 2570253

End: 2572265

Strand: Reverse

Name: cyoB

Synonym: BPSS1896

Alternate gene names: 53722917

Gene position: 2572265-2570253 (Counterclockwise)

Preceding gene: 53722918

Following gene: 53722916

Centisome position: 81.07

GC content: 63.29

Gene sequence:

>2013_bases
ATGTTCGGAAAATTGACGCTTTCGGCGATCCCGTTCGATCAGCCGATCATCATGGGCGCGGGCGCGTTCATGGTGCTCGT
CGTGCTCGGGATTCTGGGCGCGCTCACCTATACGAAGCGCTGGAAATGGCTGTGGTGCGAGTGGCTCACGACCGTCGACC
ACAAGAAGCTCGGCGTGATGTACATCATCGTTGCGCTCATCATGCTGCTGCGCGGCTTCGCCGACGCGGTGATGATGCGC
CTGCAGCTCGCGCTCGCGTACAACGGGCCCGGCTATCTGCCGCCGCACCACTACGATCAGGTGTTCACCGCGCACGGCGT
CATCATGATCTTCTTCATGGCGATGGCGTTCATGATCGGCCTGATGAACATCATCGTGCCGCTGCAGATCGGCGCGCGCG
ACGTCGCGTTTCCGTTCATCAATTCGCTGAGCTTCTGGATGACGGCGGTCTCGGCGATCCTGATCAACATCTCGCTCGTC
GTCGGCGAGTTCGCGCAGACGGGCTGGCTCGCGTATCCGCCGCTCTCGGAGCTGCAGTTCAGTCCGGGCGTCGGCGTCGA
CTATTACCTGTGGGCGCTGCAGATATCCGGCGTCGGCACGCTGCTCACGGGCGTGAACTTCTTCGTGACGATCCTGCGCA
TGCGCGCGCCCGGCATGACACTGATGAAGATGCCGGTGTTCACGTGGACGGCGCTCTGCACGAACGTGCTGATCATGGCG
TCGTTCCCGATCCTGACGGTCACGCTCGCGCTGCTCGGCCTCGACCGCTACCTCGGCATGCACTTCTTCACGAACGACGC
CGGCGGCAACGCGATGCTGTATCTGAACCTGATCTGGGCGTGGGGTCATCCGGAAGTCTACATCCTGATCCTGCCCGCGT
TCGGGATCTTCTCGGAAGTGGTCGCCACCTACGCGAAGAAGCCGCTGTTCGGCTACAAGACGATGGCGTACGCGTCGTGC
GCGATCATGGTGCTGTCGTTCCTCGTGTGGCTGCACCACTTCTTCACGATGGGTTCGGGCGCGAACGTGAACGCGTTCTT
CGGGATGATGACGATGGTGATCGCGATCCCGACCGGCGTGAAAGTGTTCAACTGGCTGTTCACGATCTATCGCGGCCGGC
TCGAATTCTCGACGCCGATCCTCTGGACGATCGGCTTCATGGTGACGTTCACGCTCGGCGGGATGACGGGCGTGATGATG
GCGATTCCCGGCGCGGACTTCGTGCTGCATAACAGCCTGTTCCTGATCGCGCACTTTCACAACGTGATCATCGGCGGCGT
GCTGTTCGGCTATCTCGCGGGCTTCAATTACTGGTTTCCGAAGGTGTTCGGCTTCAAGCTGAACGAGACGCTCGGCAAGG
CCGCGTTCTGGTTCTGGCAGGTCGGCTTCTATGTCGCGTTCGTGCCGCTGTATGTGCTCGGCTTCATGGGCATGACGCGC
CGCCTGAATCACTACGACAACCCCGCCTGGCATCCGTGGCTCATCGTCGCCGCGTGCGGCGCGGCGTTGATCGCGATCGG
CATCGCATGCCAGTTGCTGCAGCTCGCCGTCAGCCTGCGCGATCGGCGGCTGCTCGAGAACCGCGATCCGACGGGCGATC
CGTGGGGCGGACGCACGCTCGAATGGGCGACGGCTTCGCCGCCGCCCGCGTACAACTTCGCGACGATCCCGACCGTGCAC
GCGCTCGACGAGTTCGCATACCGCAAGGAGCGCGGCCTCGGCATCGGCATCGGCAAGCCGGCGGAGTATCGCGACATCCA
CATGCCGTCGAACACGAGCGCGGGCCTTTTCGTCGGCGTGTTCAGCCTCGTGCTCGGCTTCGCGGCGGTATGGCACATCT
GGTGGCTCGCGATCGCGGCGCTCGCCGGCATCCTCGTGACGGTGATTGCGTATAGCGCGGGCGAGAACGACGGCTATTAC
ATTCCGGCCGACGCCGTGCGCAGGATCGAGGAAAAACGCGGCGGCGCGCGTTTCGTCGCGCGGCCGGCGCAAGTCGAACT
GGAGGCAAACTGA

Upstream 100 bases:

>100_bases
CGACGGTCGATCCTCGGCTCTTCAATAACATCATCGCGAAGTACAACAACGGCCACGTCCTCGATCTGACGGACGCCGCC
TGTCGGACGAAGAGGTAAGC

Downstream 100 bases:

>100_bases
TGTCGTACCCATCCGTGAGCGCCGCGCCTCGTCACGCCGCGCACGATCATCCGCCGTCGCATTCGGTGTTCGGCTTCTGG
CTGTACCTGATGACCGACTG

Product: ubiquinol oxidase polypeptide I

Products: NA

Alternate protein names: Cytochrome A1 subunit 1; Oxidase BA(3) subunit 1; Ubiquinol oxidase polypeptide I [H]

Number of amino acids: Translated: 670; Mature: 670

Protein sequence:

>670_residues
MFGKLTLSAIPFDQPIIMGAGAFMVLVVLGILGALTYTKRWKWLWCEWLTTVDHKKLGVMYIIVALIMLLRGFADAVMMR
LQLALAYNGPGYLPPHHYDQVFTAHGVIMIFFMAMAFMIGLMNIIVPLQIGARDVAFPFINSLSFWMTAVSAILINISLV
VGEFAQTGWLAYPPLSELQFSPGVGVDYYLWALQISGVGTLLTGVNFFVTILRMRAPGMTLMKMPVFTWTALCTNVLIMA
SFPILTVTLALLGLDRYLGMHFFTNDAGGNAMLYLNLIWAWGHPEVYILILPAFGIFSEVVATYAKKPLFGYKTMAYASC
AIMVLSFLVWLHHFFTMGSGANVNAFFGMMTMVIAIPTGVKVFNWLFTIYRGRLEFSTPILWTIGFMVTFTLGGMTGVMM
AIPGADFVLHNSLFLIAHFHNVIIGGVLFGYLAGFNYWFPKVFGFKLNETLGKAAFWFWQVGFYVAFVPLYVLGFMGMTR
RLNHYDNPAWHPWLIVAACGAALIAIGIACQLLQLAVSLRDRRLLENRDPTGDPWGGRTLEWATASPPPAYNFATIPTVH
ALDEFAYRKERGLGIGIGKPAEYRDIHMPSNTSAGLFVGVFSLVLGFAAVWHIWWLAIAALAGILVTVIAYSAGENDGYY
IPADAVRRIEEKRGGARFVARPAQVELEAN

Sequences:

>Translated_670_residues
MFGKLTLSAIPFDQPIIMGAGAFMVLVVLGILGALTYTKRWKWLWCEWLTTVDHKKLGVMYIIVALIMLLRGFADAVMMR
LQLALAYNGPGYLPPHHYDQVFTAHGVIMIFFMAMAFMIGLMNIIVPLQIGARDVAFPFINSLSFWMTAVSAILINISLV
VGEFAQTGWLAYPPLSELQFSPGVGVDYYLWALQISGVGTLLTGVNFFVTILRMRAPGMTLMKMPVFTWTALCTNVLIMA
SFPILTVTLALLGLDRYLGMHFFTNDAGGNAMLYLNLIWAWGHPEVYILILPAFGIFSEVVATYAKKPLFGYKTMAYASC
AIMVLSFLVWLHHFFTMGSGANVNAFFGMMTMVIAIPTGVKVFNWLFTIYRGRLEFSTPILWTIGFMVTFTLGGMTGVMM
AIPGADFVLHNSLFLIAHFHNVIIGGVLFGYLAGFNYWFPKVFGFKLNETLGKAAFWFWQVGFYVAFVPLYVLGFMGMTR
RLNHYDNPAWHPWLIVAACGAALIAIGIACQLLQLAVSLRDRRLLENRDPTGDPWGGRTLEWATASPPPAYNFATIPTVH
ALDEFAYRKERGLGIGIGKPAEYRDIHMPSNTSAGLFVGVFSLVLGFAAVWHIWWLAIAALAGILVTVIAYSAGENDGYY
IPADAVRRIEEKRGGARFVARPAQVELEAN
>Mature_670_residues
MFGKLTLSAIPFDQPIIMGAGAFMVLVVLGILGALTYTKRWKWLWCEWLTTVDHKKLGVMYIIVALIMLLRGFADAVMMR
LQLALAYNGPGYLPPHHYDQVFTAHGVIMIFFMAMAFMIGLMNIIVPLQIGARDVAFPFINSLSFWMTAVSAILINISLV
VGEFAQTGWLAYPPLSELQFSPGVGVDYYLWALQISGVGTLLTGVNFFVTILRMRAPGMTLMKMPVFTWTALCTNVLIMA
SFPILTVTLALLGLDRYLGMHFFTNDAGGNAMLYLNLIWAWGHPEVYILILPAFGIFSEVVATYAKKPLFGYKTMAYASC
AIMVLSFLVWLHHFFTMGSGANVNAFFGMMTMVIAIPTGVKVFNWLFTIYRGRLEFSTPILWTIGFMVTFTLGGMTGVMM
AIPGADFVLHNSLFLIAHFHNVIIGGVLFGYLAGFNYWFPKVFGFKLNETLGKAAFWFWQVGFYVAFVPLYVLGFMGMTR
RLNHYDNPAWHPWLIVAACGAALIAIGIACQLLQLAVSLRDRRLLENRDPTGDPWGGRTLEWATASPPPAYNFATIPTVH
ALDEFAYRKERGLGIGIGKPAEYRDIHMPSNTSAGLFVGVFSLVLGFAAVWHIWWLAIAALAGILVTVIAYSAGENDGYY
IPADAVRRIEEKRGGARFVARPAQVELEAN

Specific function: Catalytic subunit of the enzyme. Electrons originating in a quinol are transferred to the bimetallic center formed by heme a and copper B [H]

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=511, Percent_Identity=39.3346379647749, Blast_Score=337, Evalue=2e-92,
Organism=Escherichia coli, GI1786634, Length=654, Percent_Identity=67.125382262997, Blast_Score=926, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6226519, Length=537, Percent_Identity=37.9888268156425, Blast_Score=355, Evalue=2e-98,
Organism=Saccharomyces cerevisiae, GI6226524, Length=325, Percent_Identity=43.0769230769231, Blast_Score=251, Evalue=3e-67,
Organism=Saccharomyces cerevisiae, GI6226523, Length=245, Percent_Identity=35.1020408163265, Blast_Score=137, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014207 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: 1.10.3.-

Molecular weight: Translated: 74400; Mature: 74400

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGKLTLSAIPFDQPIIMGAGAFMVLVVLGILGALTYTKRWKWLWCEWLTTVDHKKLGVM
CCCCEEEEECCCCCCCEECCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCHHHHHHH
YIIVALIMLLRGFADAVMMRLQLALAYNGPGYLPPHHYDQVFTAHGVIMIFFMAMAFMIG
HHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LMNIIVPLQIGARDVAFPFINSLSFWMTAVSAILINISLVVGEFAQTGWLAYPPLSELQF
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHCCC
SPGVGVDYYLWALQISGVGTLLTGVNFFVTILRMRAPGMTLMKMPVFTWTALCTNVLIMA
CCCCCCHHEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
SFPILTVTLALLGLDRYLGMHFFTNDAGGNAMLYLNLIWAWGHPEVYILILPAFGIFSEV
CCHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEEEEEEECCCCCEEEEEECHHHHHHHH
VATYAKKPLFGYKTMAYASCAIMVLSFLVWLHHFFTMGSGANVNAFFGMMTMVIAIPTGV
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCH
KVFNWLFTIYRGRLEFSTPILWTIGFMVTFTLGGMTGVMMAIPGADFVLHNSLFLIAHFH
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHCCCCCCCHHHCCHHHHHHHH
NVIIGGVLFGYLAGFNYWFPKVFGFKLNETLGKAAFWFWQVGFYVAFVPLYVLGFMGMTR
HHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLNHYDNPAWHPWLIVAACGAALIAIGIACQLLQLAVSLRDRRLLENRDPTGDPWGGRTL
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEE
EWATASPPPAYNFATIPTVHALDEFAYRKERGLGIGIGKPAEYRDIHMPSNTSAGLFVGV
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCHHHHHH
FSLVLGFAAVWHIWWLAIAALAGILVTVIAYSAGENDGYYIPADAVRRIEEKRGGARFVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHCCCCEEEE
RPAQVELEAN
CCCEEEEECC
>Mature Secondary Structure
MFGKLTLSAIPFDQPIIMGAGAFMVLVVLGILGALTYTKRWKWLWCEWLTTVDHKKLGVM
CCCCEEEEECCCCCCCEECCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCHHHHHHH
YIIVALIMLLRGFADAVMMRLQLALAYNGPGYLPPHHYDQVFTAHGVIMIFFMAMAFMIG
HHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LMNIIVPLQIGARDVAFPFINSLSFWMTAVSAILINISLVVGEFAQTGWLAYPPLSELQF
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHCCC
SPGVGVDYYLWALQISGVGTLLTGVNFFVTILRMRAPGMTLMKMPVFTWTALCTNVLIMA
CCCCCCHHEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
SFPILTVTLALLGLDRYLGMHFFTNDAGGNAMLYLNLIWAWGHPEVYILILPAFGIFSEV
CCHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEEEEEEECCCCCEEEEEECHHHHHHHH
VATYAKKPLFGYKTMAYASCAIMVLSFLVWLHHFFTMGSGANVNAFFGMMTMVIAIPTGV
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCH
KVFNWLFTIYRGRLEFSTPILWTIGFMVTFTLGGMTGVMMAIPGADFVLHNSLFLIAHFH
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHCCCCCCCHHHCCHHHHHHHH
NVIIGGVLFGYLAGFNYWFPKVFGFKLNETLGKAAFWFWQVGFYVAFVPLYVLGFMGMTR
HHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLNHYDNPAWHPWLIVAACGAALIAIGIACQLLQLAVSLRDRRLLENRDPTGDPWGGRTL
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEE
EWATASPPPAYNFATIPTVHALDEFAYRKERGLGIGIGKPAEYRDIHMPSNTSAGLFVGV
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCHHHHHH
FSLVLGFAAVWHIWWLAIAALAGILVTVIAYSAGENDGYYIPADAVRRIEEKRGGARFVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHCCCCEEEE
RPAQVELEAN
CCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Protoheme IX (Heme B55 and B562); Copper B. [C]

Metal ions: Fe; Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8392509 [H]