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The map label for this gene is frzE [H]

Identifier: 53722891

GI number: 53722891

Start: 2541314

End: 2543908

Strand: Reverse

Name: frzE [H]

Synonym: BPSS1871

Alternate gene names: 53722891

Gene position: 2543908-2541314 (Counterclockwise)

Preceding gene: 53722892

Following gene: 53722890

Centisome position: 80.17

GC content: 71.95

Gene sequence:

>2595_bases
ATGAGCACCGACGACGATTTCGGCCGCGCGTCGCTGCTCGAGCTGTTTCGCGAGGAGACGCACACGCAGACGCAGGCGCT
GTCCGAGCGGCTGCTCGCGCTCGAGCGCGGCGCGCAGGATGCGGCGACGCTCGAGGCGTGCATGCGCGCCGCGCATTCGC
TCAAGGGCGCGGCGCGCATCGTCGGCGTGCCGCAGGGCGTCGACATCGCGGGGCGGATGGAGGATTGCTTCGTCGCCGCG
CAGCACGGCCGGCAGCCGCTCACGCCGTGCCATGTCGACGCGCTGCTCACGGGCGTCGATCTGCTCGTGCGCGTCGGCGA
TCCGCAGACGGCGGCGTCGGTCGCGCCGCACGAGATCGACGCGTTCGCGGCGGCGCTCGCGGCCGCGGATGCGGGCGTGG
AGCCGGGCGCCGATGCGCGCGGAGCGAACGCATACGAGAGCGACGGCAACGCGCACGAACGCGGCGGCGCGGCGCGCGCA
AGCGTCGCCGCCGCACCGGGCGAGGCCGCCGATGCGTCGCGCGAAAGCGGCGCGCGTGAGGCGGCCGGCCCGAATCGCGC
GGGCGCGGCGGCGGGCGCCGCCGATGTCCGCGCGAGCGCGGATGCCGGCGACGCGCGCGGTGCGAGCGACACGCGCGACG
TGCGGCGCACGGCCGGTGCACGCGGCGCGAACCGTTCGACGGAGGTTTTCGGCGCGGGCGAAGCGACCGGCATCGGCGCG
TCGACCCATGCGAATGACGCGAACGGCATGAACGCCACGAACCTCGCGACATCGGCGGCCCATCCGCCGCGCGGCGCATT
CGCCGCGGCGCACGACGCGCCGCCGTCTTCCGCCCCGTCCGACGCGCCGCGCGCGCCGAGCCAGATGCGCCGCGTGCGCG
CCGATACGCTGAACCGGCTGCTGAGCCTGTCCGGCGAATCGCTCGTCGAGTCGCGCTGGCTGAAGCCGTTCGCCGAATCG
ATGCTGCGCGTGAAGCGCGCGCAGCGCGACGCGGCCCGCTCGCTCGATTCGGCCGTCGAGGCGCTCGCCGACGACGCGGA
CCCGCGCGTGCGCGGCGCGCTCAACGAGGCGCGGCAGATGTTCACCGATCTGCAGCGCACGTTCGCGGCGCGGCTCGACG
AGCTCGACCGCTTCGAGCGCCGCAGCTCGCACATCGCCGAGCAACTGTACGACGAGGCGCTGCAATGCCGGATGCGCCCG
TTCGGCGACGCGACGCGCGCTTACCCGCGCGTCGTGCGCGATCTCGCCCGCTCGCTCGGCAAACGTGTGCGCTTCTCGAT
CGTCGGCGAAGCGACGCAGGTCGATCGCGACATCCTCGACATGCTCGACGCGCCGCTCGGCCATTTGCTGCGCAACGCGC
TCGATCACGGCGTCGAGCCGCCCGAGGTGCGGCTCGCGCGCGGCAAGCCGGCGGAGGCCACCATCACGCTCGAGGCGCGG
CACAGCGCCGGCTCGCTGCTCGTCAGCGTGAGCGACGACGGCCCCGGCGCCGATCTCGCCGCGGTGCGCGCGGCGATCGT
GCGCCACCACCTGACCGACGAGGATACGGCCGCGCGCCTGTCCGATCAGGAACTGCTCGAATTCCTGCTGCTGCCCGGCT
TCTCGATGCGCGAGCGGGTGACCGACGTGTCGGGCCGCGGCGTCGGCCTCGACGCGGTGCAGGAAATGGTGAAGTCGGTG
CGCGGCGCGGTGCGCATCTTCAACGAGCCGGGCCTCGGCATGCGCTTCGTGCTGCAGTTGCCGCTCACGCTGTCGGTGAT
CCGCAGCCTGATCGTCGACGTCGGCGGCGAGCCGTACGCGTTCCCGCTCGTGCAGGTGCGCCGCACGCTCGAGCTCGAGC
GCGCGGACATCGACGTGCTCGAAGGCCAGCAGCACTTTCCGCTCGACGATCGCCGCGTCGGCCTCGTCACCGCGCATCAA
CTGCTCGACGCGGGCGAGCTCGACGAAAGCCGGCCGGCGACGGCCGTCGTCGTCGTCGGAGGCGAGCCGGAAACCTACGG
CGTCGCGGTGGACCGCTTCCTCGGCGAGCGGATGCTCGTGGTGCAGCCGTTAGACGGACGCCTCAACAAAATTCAGAACA
TTGCGGCGGGCGCTTTGCTGGAAAATGGCGATCCGGTGCTGATCGTCGACGTCGAGGATCTGATCCGCTCGATCGACAAG
CTGATTCGCGGCGGCCAGCTCGCGAAGGTGCGGCGCGGCGATCGGGACGCGCTCGCGCGGCGCGCGAAGCGCGTGCTCGT
GGTCGACGATTCGCTGACCGTGCGCGAGCTCGAGCGCAAGCTGCTCGAGAAGCGCGGCTACGACGTGACGATCGCGATCG
ACGGCATGGACGGCTGGAACGCGATCCGCGGCGACGTGTTCGATCTCGTCGTCACCGACATCGACATGCCGCGCATGGAC
GGCATCGAGCTCGTCACGCTGATCAAGGGCGATCCGCTGCTCAAATCGGTGCCCGTGATGATCGTGTCGTACAAGGATCG
CGACGAGGACCGGCGGCGCGGGCTCGAAGCGGGCGCCGACTATTACCTGGCGAAGGGCGGCTTCCATGACGAGGCGTTGC
TCGACGCCGTGCACGACCTGATTGGGGACGCGTAG

Upstream 100 bases:

>100_bases
CGGGCGCCGTGCATTCGCGCGGCGTGTTCGCGTGGCGCGGCAAGTCGATCGGCCTGCTCGACGAAGATCGCCTGTTCGAT
TCGCTGACGCGGAGCCTGCG

Downstream 100 bases:

>100_bases
AAAGCCATGAACATCGGCATCGTCAACGACTTGCCGCTCGCCGTCGAGGCGCTGCGCCGCACGATCGCGCTGCGGCCCGA
GCACCGCGTGCTGTGGGTCG

Product: chemotaxis-related histidine kinase protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 864; Mature: 863

Protein sequence:

>864_residues
MSTDDDFGRASLLELFREETHTQTQALSERLLALERGAQDAATLEACMRAAHSLKGAARIVGVPQGVDIAGRMEDCFVAA
QHGRQPLTPCHVDALLTGVDLLVRVGDPQTAASVAPHEIDAFAAALAAADAGVEPGADARGANAYESDGNAHERGGAARA
SVAAAPGEAADASRESGAREAAGPNRAGAAAGAADVRASADAGDARGASDTRDVRRTAGARGANRSTEVFGAGEATGIGA
STHANDANGMNATNLATSAAHPPRGAFAAAHDAPPSSAPSDAPRAPSQMRRVRADTLNRLLSLSGESLVESRWLKPFAES
MLRVKRAQRDAARSLDSAVEALADDADPRVRGALNEARQMFTDLQRTFAARLDELDRFERRSSHIAEQLYDEALQCRMRP
FGDATRAYPRVVRDLARSLGKRVRFSIVGEATQVDRDILDMLDAPLGHLLRNALDHGVEPPEVRLARGKPAEATITLEAR
HSAGSLLVSVSDDGPGADLAAVRAAIVRHHLTDEDTAARLSDQELLEFLLLPGFSMRERVTDVSGRGVGLDAVQEMVKSV
RGAVRIFNEPGLGMRFVLQLPLTLSVIRSLIVDVGGEPYAFPLVQVRRTLELERADIDVLEGQQHFPLDDRRVGLVTAHQ
LLDAGELDESRPATAVVVVGGEPETYGVAVDRFLGERMLVVQPLDGRLNKIQNIAAGALLENGDPVLIVDVEDLIRSIDK
LIRGGQLAKVRRGDRDALARRAKRVLVVDDSLTVRELERKLLEKRGYDVTIAIDGMDGWNAIRGDVFDLVVTDIDMPRMD
GIELVTLIKGDPLLKSVPVMIVSYKDRDEDRRRGLEAGADYYLAKGGFHDEALLDAVHDLIGDA

Sequences:

>Translated_864_residues
MSTDDDFGRASLLELFREETHTQTQALSERLLALERGAQDAATLEACMRAAHSLKGAARIVGVPQGVDIAGRMEDCFVAA
QHGRQPLTPCHVDALLTGVDLLVRVGDPQTAASVAPHEIDAFAAALAAADAGVEPGADARGANAYESDGNAHERGGAARA
SVAAAPGEAADASRESGAREAAGPNRAGAAAGAADVRASADAGDARGASDTRDVRRTAGARGANRSTEVFGAGEATGIGA
STHANDANGMNATNLATSAAHPPRGAFAAAHDAPPSSAPSDAPRAPSQMRRVRADTLNRLLSLSGESLVESRWLKPFAES
MLRVKRAQRDAARSLDSAVEALADDADPRVRGALNEARQMFTDLQRTFAARLDELDRFERRSSHIAEQLYDEALQCRMRP
FGDATRAYPRVVRDLARSLGKRVRFSIVGEATQVDRDILDMLDAPLGHLLRNALDHGVEPPEVRLARGKPAEATITLEAR
HSAGSLLVSVSDDGPGADLAAVRAAIVRHHLTDEDTAARLSDQELLEFLLLPGFSMRERVTDVSGRGVGLDAVQEMVKSV
RGAVRIFNEPGLGMRFVLQLPLTLSVIRSLIVDVGGEPYAFPLVQVRRTLELERADIDVLEGQQHFPLDDRRVGLVTAHQ
LLDAGELDESRPATAVVVVGGEPETYGVAVDRFLGERMLVVQPLDGRLNKIQNIAAGALLENGDPVLIVDVEDLIRSIDK
LIRGGQLAKVRRGDRDALARRAKRVLVVDDSLTVRELERKLLEKRGYDVTIAIDGMDGWNAIRGDVFDLVVTDIDMPRMD
GIELVTLIKGDPLLKSVPVMIVSYKDRDEDRRRGLEAGADYYLAKGGFHDEALLDAVHDLIGDA
>Mature_863_residues
STDDDFGRASLLELFREETHTQTQALSERLLALERGAQDAATLEACMRAAHSLKGAARIVGVPQGVDIAGRMEDCFVAAQ
HGRQPLTPCHVDALLTGVDLLVRVGDPQTAASVAPHEIDAFAAALAAADAGVEPGADARGANAYESDGNAHERGGAARAS
VAAAPGEAADASRESGAREAAGPNRAGAAAGAADVRASADAGDARGASDTRDVRRTAGARGANRSTEVFGAGEATGIGAS
THANDANGMNATNLATSAAHPPRGAFAAAHDAPPSSAPSDAPRAPSQMRRVRADTLNRLLSLSGESLVESRWLKPFAESM
LRVKRAQRDAARSLDSAVEALADDADPRVRGALNEARQMFTDLQRTFAARLDELDRFERRSSHIAEQLYDEALQCRMRPF
GDATRAYPRVVRDLARSLGKRVRFSIVGEATQVDRDILDMLDAPLGHLLRNALDHGVEPPEVRLARGKPAEATITLEARH
SAGSLLVSVSDDGPGADLAAVRAAIVRHHLTDEDTAARLSDQELLEFLLLPGFSMRERVTDVSGRGVGLDAVQEMVKSVR
GAVRIFNEPGLGMRFVLQLPLTLSVIRSLIVDVGGEPYAFPLVQVRRTLELERADIDVLEGQQHFPLDDRRVGLVTAHQL
LDAGELDESRPATAVVVVGGEPETYGVAVDRFLGERMLVVQPLDGRLNKIQNIAAGALLENGDPVLIVDVEDLIRSIDKL
IRGGQLAKVRRGDRDALARRAKRVLVVDDSLTVRELERKLLEKRGYDVTIAIDGMDGWNAIRGDVFDLVVTDIDMPRMDG
IELVTLIKGDPLLKSVPVMIVSYKDRDEDRRRGLEAGADYYLAKGGFHDEALLDAVHDLIGDA

Specific function: FrzE is involved in a sensory transduction pathway that controls the frequency at which cells reverse their gliding direction. FrzE seems to be capable of autophosphorylating itself on an histidine residue and then to transfer that group to an aspartate r

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=696, Percent_Identity=26.867816091954, Blast_Score=200, Evalue=4e-52,
Organism=Escherichia coli, GI1788191, Length=109, Percent_Identity=34.8623853211009, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1786599, Length=104, Percent_Identity=33.6538461538462, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR011006
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR005467
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01584 CheW; PF02518 HATPase_c; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 92515; Mature: 92384

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTDDDFGRASLLELFREETHTQTQALSERLLALERGAQDAATLEACMRAAHSLKGAARI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHE
VGVPQGVDIAGRMEDCFVAAQHGRQPLTPCHVDALLTGVDLLVRVGDPQTAASVAPHEID
EECCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHEECCCCCHHHHCCCHHHH
AFAAALAAADAGVEPGADARGANAYESDGNAHERGGAARASVAAAPGEAADASRESGARE
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHCCCCHHHHHCCCCCCHHCCHHHCCCCC
AAGPNRAGAAAGAADVRASADAGDARGASDTRDVRRTAGARGANRSTEVFGAGEATGIGA
CCCCCCCCCCCCCHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEECCCCCCCCC
STHANDANGMNATNLATSAAHPPRGAFAAAHDAPPSSAPSDAPRAPSQMRRVRADTLNRL
CCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LSLSGESLVESRWLKPFAESMLRVKRAQRDAARSLDSAVEALADDADPRVRGALNEARQM
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
FTDLQRTFAARLDELDRFERRSSHIAEQLYDEALQCRMRPFGDATRAYPRVVRDLARSLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
KRVRFSIVGEATQVDRDILDMLDAPLGHLLRNALDHGVEPPEVRLARGKPAEATITLEAR
HHEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEECCCCCCEEEEEEEC
HSAGSLLVSVSDDGPGADLAAVRAAIVRHHLTDEDTAARLSDQELLEFLLLPGFSMRERV
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHCCCCCHHHHH
TDVSGRGVGLDAVQEMVKSVRGAVRIFNEPGLGMRFVLQLPLTLSVIRSLIVDVGGEPYA
HCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
FPLVQVRRTLELERADIDVLEGQQHFPLDDRRVGLVTAHQLLDAGELDESRPATAVVVVG
HHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEC
GEPETYGVAVDRFLGERMLVVQPLDGRLNKIQNIAAGALLENGDPVLIVDVEDLIRSIDK
CCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHEEECCCCEEEEEHHHHHHHHHH
LIRGGQLAKVRRGDRDALARRAKRVLVVDDSLTVRELERKLLEKRGYDVTIAIDGMDGWN
HHCCCCCHHHHCCCHHHHHHHHCEEEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCCCH
AIRGDVFDLVVTDIDMPRMDGIELVTLIKGDPLLKSVPVMIVSYKDRDEDRRRGLEAGAD
HHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHCCCEEEEEECCCCHHHHCCHHCCCC
YYLAKGGFHDEALLDAVHDLIGDA
EEEECCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STDDDFGRASLLELFREETHTQTQALSERLLALERGAQDAATLEACMRAAHSLKGAARI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHE
VGVPQGVDIAGRMEDCFVAAQHGRQPLTPCHVDALLTGVDLLVRVGDPQTAASVAPHEID
EECCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHEECCCCCHHHHCCCHHHH
AFAAALAAADAGVEPGADARGANAYESDGNAHERGGAARASVAAAPGEAADASRESGARE
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHCCCCHHHHHCCCCCCHHCCHHHCCCCC
AAGPNRAGAAAGAADVRASADAGDARGASDTRDVRRTAGARGANRSTEVFGAGEATGIGA
CCCCCCCCCCCCCHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEECCCCCCCCC
STHANDANGMNATNLATSAAHPPRGAFAAAHDAPPSSAPSDAPRAPSQMRRVRADTLNRL
CCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LSLSGESLVESRWLKPFAESMLRVKRAQRDAARSLDSAVEALADDADPRVRGALNEARQM
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
FTDLQRTFAARLDELDRFERRSSHIAEQLYDEALQCRMRPFGDATRAYPRVVRDLARSLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
KRVRFSIVGEATQVDRDILDMLDAPLGHLLRNALDHGVEPPEVRLARGKPAEATITLEAR
HHEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEECCCCCCEEEEEEEC
HSAGSLLVSVSDDGPGADLAAVRAAIVRHHLTDEDTAARLSDQELLEFLLLPGFSMRERV
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHCCCCCHHHHH
TDVSGRGVGLDAVQEMVKSVRGAVRIFNEPGLGMRFVLQLPLTLSVIRSLIVDVGGEPYA
HCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
FPLVQVRRTLELERADIDVLEGQQHFPLDDRRVGLVTAHQLLDAGELDESRPATAVVVVG
HHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEC
GEPETYGVAVDRFLGERMLVVQPLDGRLNKIQNIAAGALLENGDPVLIVDVEDLIRSIDK
CCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHEEECCCCEEEEEHHHHHHHHHH
LIRGGQLAKVRRGDRDALARRAKRVLVVDDSLTVRELERKLLEKRGYDVTIAIDGMDGWN
HHCCCCCHHHHCCCHHHHHHHHCEEEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCCCH
AIRGDVFDLVVTDIDMPRMDGIELVTLIKGDPLLKSVPVMIVSYKDRDEDRRRGLEAGAD
HHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHCCCEEEEEECCCCHHHHCCHHCCCC
YYLAKGGFHDEALLDAVHDLIGDA
EEEECCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2165608; 2123853 [H]