Click here to switch to the map view.

The map label for this gene is gltA

Identifier: 53722736

GI number: 53722736

Start: 2354425

End: 2355726

Strand: Reverse

Name: gltA

Synonym: BPSS1715

Alternate gene names: 53722736

Gene position: 2355726-2354425 (Counterclockwise)

Preceding gene: 53722737

Following gene: 53722734

Centisome position: 74.24

GC content: 62.6

Gene sequence:

>1302_bases
ATGACCCCGTCTGATGTTAAAGCCACGCTATCGTTCAGCGATAATTCGCCGAGCGTCGAACTGCCGATCTACAAGGGTAC
GATGGGCCCCGACGTGATCGATATCCGCAAGCTGTACGGCCAGACCGGCAAGTTCACGTACGACCCGGGCTTCATGTCGA
CGGCGTCGTGCAACTCGGCGATCACGTACATCGACGGCGACAAGGGCGAACTGCTGTACCGCGGCTACCCGATCGACAAT
CTCGCGCAAAACGCGGACTTCCTCGAATCCTGCTATCTGCTGCTCAAGGGCGAACTGCCGAACGCGGCGCAGAAGAAGGA
GTTCGTGGCCACCGTCACGAAGCACACGATGGTGCACGAGCAGATGCAGTTCTTCTTCCGGGGTTTCCGCCGCGACGCGC
ACCCGATGGCGATTCTCGTCGCCGCGGTCGGCGCGCTGTCCGCGTTCTACCACGATTCGCTCGACATCAATGATCCGCGT
CACCGCGAAGTGTCGGCGATCCGCATGATCGCGAAGCTGCCGACGCTCGTCGCGATGGCGTACAAGTACAGCATCGGCCA
GCCGTTCGTGTATCCGCGCAACGATCTGTCGTACAGCGCGAACTTCATGCGCATGATGTTCGCGAACCCGTGCGAGGAAT
ATCAGGTCAACGACGTGCTCGTCCGCGCGCTCGACCGTATCCTGATCCTGCATGCCGACCACGAGCAGAACGCGTCGACG
TCGACGGTCCGCCTCGCCGGCTCGTCGGGCGCGAACCCGTTCGCGTGTATCGCGGCCGGCATCGCGTGCTTGTGGGGCCC
GGCGCACGGCGGCGCGAACGAAGCCGCGCTGAACATGCTCGAGCAGATCGGCACGCCGGAGAACATTCCCGAGTTCATCA
AGCAGGTGAAGGACAAGAACTCGGGCGTGAAGCTGATGGGCTTCGGCCACCGCGTGTACAAGAACTACGATCCGCGCGCG
AAGCTGATGCGCGAAACGTGCTACGAAGTGCTCAACGAGCTGGGCCTGCACGACGATCCGCTGTTCAAGCTCGCGATGCA
GCTCGAGAAGATCGCGCTCGAAGACGAATACTTCGTGTCGCGCAAGCTGTACCCGAACGTCGACTTCTACTCGGGCATCG
TCCAGCGCGCGCTCGGCATCCCGACGTCGATGTTCACCTGCATCTTCGCGATGGCGCGCACGGTCGGCTGGATCGCGCAG
TGGAACGAGATGATCGCCGATCCGGAGCAGAAGATCGGCCGTCCGCGGCAGCTCTTCATCGGCGAAACGCCGCGCACGGC
GAAGCCGATCGAGCAGCGCTGA

Upstream 100 bases:

>100_bases
GCCGGCCCGGACATGTCCAGGCTGCTGGAGATGCTGCGCAGCGTTTGAGAGCGTTGTGCCCGTTATCGAATCCGTTTCTA
TTTTCGATTGAGGATGTGTC

Downstream 100 bases:

>100_bases
TCGGCGGCGCGGCGCGTGCGGGCGGCTCGCCGCGCACGCCGCGCGTCATGTGCGACGAAACACCCCGACGGGTTCGCCTG
TCGGGGTGTTTCGCTTTCAG

Product: type II citrate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 432

Protein sequence:

>433_residues
MTPSDVKATLSFSDNSPSVELPIYKGTMGPDVIDIRKLYGQTGKFTYDPGFMSTASCNSAITYIDGDKGELLYRGYPIDN
LAQNADFLESCYLLLKGELPNAAQKKEFVATVTKHTMVHEQMQFFFRGFRRDAHPMAILVAAVGALSAFYHDSLDINDPR
HREVSAIRMIAKLPTLVAMAYKYSIGQPFVYPRNDLSYSANFMRMMFANPCEEYQVNDVLVRALDRILILHADHEQNAST
STVRLAGSSGANPFACIAAGIACLWGPAHGGANEAALNMLEQIGTPENIPEFIKQVKDKNSGVKLMGFGHRVYKNYDPRA
KLMRETCYEVLNELGLHDDPLFKLAMQLEKIALEDEYFVSRKLYPNVDFYSGIVQRALGIPTSMFTCIFAMARTVGWIAQ
WNEMIADPEQKIGRPRQLFIGETPRTAKPIEQR

Sequences:

>Translated_433_residues
MTPSDVKATLSFSDNSPSVELPIYKGTMGPDVIDIRKLYGQTGKFTYDPGFMSTASCNSAITYIDGDKGELLYRGYPIDN
LAQNADFLESCYLLLKGELPNAAQKKEFVATVTKHTMVHEQMQFFFRGFRRDAHPMAILVAAVGALSAFYHDSLDINDPR
HREVSAIRMIAKLPTLVAMAYKYSIGQPFVYPRNDLSYSANFMRMMFANPCEEYQVNDVLVRALDRILILHADHEQNAST
STVRLAGSSGANPFACIAAGIACLWGPAHGGANEAALNMLEQIGTPENIPEFIKQVKDKNSGVKLMGFGHRVYKNYDPRA
KLMRETCYEVLNELGLHDDPLFKLAMQLEKIALEDEYFVSRKLYPNVDFYSGIVQRALGIPTSMFTCIFAMARTVGWIAQ
WNEMIADPEQKIGRPRQLFIGETPRTAKPIEQR
>Mature_432_residues
TPSDVKATLSFSDNSPSVELPIYKGTMGPDVIDIRKLYGQTGKFTYDPGFMSTASCNSAITYIDGDKGELLYRGYPIDNL
AQNADFLESCYLLLKGELPNAAQKKEFVATVTKHTMVHEQMQFFFRGFRRDAHPMAILVAAVGALSAFYHDSLDINDPRH
REVSAIRMIAKLPTLVAMAYKYSIGQPFVYPRNDLSYSANFMRMMFANPCEEYQVNDVLVRALDRILILHADHEQNASTS
TVRLAGSSGANPFACIAAGIACLWGPAHGGANEAALNMLEQIGTPENIPEFIKQVKDKNSGVKLMGFGHRVYKNYDPRAK
LMRETCYEVLNELGLHDDPLFKLAMQLEKIALEDEYFVSRKLYPNVDFYSGIVQRALGIPTSMFTCIFAMARTVGWIAQW
NEMIADPEQKIGRPRQLFIGETPRTAKPIEQR

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0372

COG function: function code C; Citrate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the citrate synthase family [H]

Homologues:

Organism=Homo sapiens, GI38327625, Length=353, Percent_Identity=29.1784702549575, Blast_Score=114, Evalue=1e-25,
Organism=Escherichia coli, GI1786939, Length=430, Percent_Identity=66.046511627907, Blast_Score=611, Evalue=1e-176,
Organism=Escherichia coli, GI1786527, Length=387, Percent_Identity=29.1989664082687, Blast_Score=157, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17555174, Length=413, Percent_Identity=27.6029055690073, Blast_Score=115, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6324328, Length=375, Percent_Identity=26.1333333333333, Blast_Score=106, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6319850, Length=365, Percent_Identity=27.3972602739726, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6325257, Length=368, Percent_Identity=23.9130434782609, Blast_Score=83, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24640124, Length=424, Percent_Identity=26.8867924528302, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24640126, Length=424, Percent_Identity=26.8867924528302, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI21356863, Length=425, Percent_Identity=26.3529411764706, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: 624 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016142
- InterPro:   IPR016143
- InterPro:   IPR002020
- InterPro:   IPR016141
- InterPro:   IPR019810
- InterPro:   IPR010953 [H]

Pfam domain/function: PF00285 Citrate_synt [H]

EC number: =2.3.3.1 [H]

Molecular weight: Translated: 48533; Mature: 48402

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS00480 CITRATE_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPSDVKATLSFSDNSPSVELPIYKGTMGPDVIDIRKLYGQTGKFTYDPGFMSTASCNSA
CCCCCCEEEEEECCCCCCEEEEEEECCCCCCHHHHHHHHCCCCCEEECCCCCCCCCCCCE
ITYIDGDKGELLYRGYPIDNLAQNADFLESCYLLLKGELPNAAQKKEFVATVTKHTMVHE
EEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
QMQFFFRGFRRDAHPMAILVAAVGALSAFYHDSLDINDPRHREVSAIRMIAKLPTLVAMA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
YKYSIGQPFVYPRNDLSYSANFMRMMFANPCEEYQVNDVLVRALDRILILHADHEQNAST
HHHHCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCC
STVRLAGSSGANPFACIAAGIACLWGPAHGGANEAALNMLEQIGTPENIPEFIKQVKDKN
CEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCC
SGVKLMGFGHRVYKNYDPRAKLMRETCYEVLNELGLHDDPLFKLAMQLEKIALEDEYFVS
CCEEEEECCHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHH
RKLYPNVDFYSGIVQRALGIPTSMFTCIFAMARTVGWIAQWNEMIADPEQKIGRPRQLFI
HCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEE
GETPRTAKPIEQR
CCCCCCCCCCCCC
>Mature Secondary Structure 
TPSDVKATLSFSDNSPSVELPIYKGTMGPDVIDIRKLYGQTGKFTYDPGFMSTASCNSA
CCCCCEEEEEECCCCCCEEEEEEECCCCCCHHHHHHHHCCCCCEEECCCCCCCCCCCCE
ITYIDGDKGELLYRGYPIDNLAQNADFLESCYLLLKGELPNAAQKKEFVATVTKHTMVHE
EEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
QMQFFFRGFRRDAHPMAILVAAVGALSAFYHDSLDINDPRHREVSAIRMIAKLPTLVAMA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
YKYSIGQPFVYPRNDLSYSANFMRMMFANPCEEYQVNDVLVRALDRILILHADHEQNAST
HHHHCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCC
STVRLAGSSGANPFACIAAGIACLWGPAHGGANEAALNMLEQIGTPENIPEFIKQVKDKN
CEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCC
SGVKLMGFGHRVYKNYDPRAKLMRETCYEVLNELGLHDDPLFKLAMQLEKIALEDEYFVS
CCEEEEECCHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHH
RKLYPNVDFYSGIVQRALGIPTSMFTCIFAMARTVGWIAQWNEMIADPEQKIGRPRQLFI
HCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEE
GETPRTAKPIEQR
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]