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The map label for this gene is trpA

Identifier: 53722717

GI number: 53722717

Start: 2331539

End: 2332354

Strand: Reverse

Name: trpA

Synonym: BPSS1697

Alternate gene names: 53722717

Gene position: 2332354-2331539 (Counterclockwise)

Preceding gene: 53722718

Following gene: 53722716

Centisome position: 73.51

GC content: 70.22

Gene sequence:

>816_bases
ATGTCCCGTATTCAGAACACTTTTGCCGCACTCGCCGCCCAAGGTCGCAAGGGGCTGATTCCGTTCATCACCGCGGGAGA
CCCGGACCCGGCGAAGACCGTCGAGCTGATGCACGCGCTCGCCGAAGGCGGCGCCGACGTGATCGAGCTCGGCGTGCCGT
TCTCCGATCCGATGGCCGACGGCCCCGTGATCCAGCGCTCGTCGGAGCGCGCGCTCGCGAAAGGCGTGACGCTTCACAGC
GTGCTCGACGACGTGAAGCGCTTTCGCGCGCGCGACCAGAAGACGCCCGTCGTGCTGATGGGCTACGCGAATCCGATCGA
GCGCATGGGCGCGGACGCATTCGCCGCGGCCGCGCGCGACGCGGGCGTCGACGGCGTGCTCGTCGTCGACTATCCGCCCG
AGGAATCGCACGATTTCGCCGCGAAGATGCGCGCGGCGGGCATCGATCCGATCTTCCTGCTCGCGCCGACGTCGACCGAC
GACCGGATCGCCGCCGTCGGCCAGGTGGCGAGCGGCTACGTCTACTATGTGTCGCTCAAGGGGGTGACGGGCGCCGCAAA
TCTGGATGTTTCCAGCATTGCGGGTAAAATCCCGGCCATCAAGTCGCGCGTGCCGCTTCCCGTCGGGGTCGGTTTCGGCA
TCCGCGACGCCGCGACGGCGCGCGCGGTGGCCGAGGTGGCGGACGCCGTCGTGATCGGCAGCCGCCTTGTCCAGCTGCTG
GAGCAGGCCGCGCCGGAGCGGGCCGCCGCCGAGCTCGCGGGGTTCGTCGCCGAGCTGCGCGTCGCGATCGACGGCGCGGC
GAAGCCGGCGGCATGA

Upstream 100 bases:

>100_bases
ATCGCGCGCGAACGCGTCGCGTCGCTCGCGGCCGTCTCCGCGCCGGCCGACGCGTAAGCGGCGCGGCGCGCGCGATAGCG
AACGATCTGGAAAAAAAGCC

Downstream 100 bases:

>100_bases
GCCGCGCGACACGTCAACACAAGCTGACCGCGAACCGGGTGCGCCATGCCCGGTTCGCCACCGAACAGGAAACCATACGA
TGAGCTGGCTCGACAAACTG

Product: tryptophan synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MSRIQNTFAALAAQGRKGLIPFITAGDPDPAKTVELMHALAEGGADVIELGVPFSDPMADGPVIQRSSERALAKGVTLHS
VLDDVKRFRARDQKTPVVLMGYANPIERMGADAFAAAARDAGVDGVLVVDYPPEESHDFAAKMRAAGIDPIFLLAPTSTD
DRIAAVGQVASGYVYYVSLKGVTGAANLDVSSIAGKIPAIKSRVPLPVGVGFGIRDAATARAVAEVADAVVIGSRLVQLL
EQAAPERAAAELAGFVAELRVAIDGAAKPAA

Sequences:

>Translated_271_residues
MSRIQNTFAALAAQGRKGLIPFITAGDPDPAKTVELMHALAEGGADVIELGVPFSDPMADGPVIQRSSERALAKGVTLHS
VLDDVKRFRARDQKTPVVLMGYANPIERMGADAFAAAARDAGVDGVLVVDYPPEESHDFAAKMRAAGIDPIFLLAPTSTD
DRIAAVGQVASGYVYYVSLKGVTGAANLDVSSIAGKIPAIKSRVPLPVGVGFGIRDAATARAVAEVADAVVIGSRLVQLL
EQAAPERAAAELAGFVAELRVAIDGAAKPAA
>Mature_270_residues
SRIQNTFAALAAQGRKGLIPFITAGDPDPAKTVELMHALAEGGADVIELGVPFSDPMADGPVIQRSSERALAKGVTLHSV
LDDVKRFRARDQKTPVVLMGYANPIERMGADAFAAAARDAGVDGVLVVDYPPEESHDFAAKMRAAGIDPIFLLAPTSTDD
RIAAVGQVASGYVYYVSLKGVTGAANLDVSSIAGKIPAIKSRVPLPVGVGFGIRDAATARAVAEVADAVVIGSRLVQLLE
QAAPERAAAELAGFVAELRVAIDGAAKPAA

Specific function: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate [H]

COG id: COG0159

COG function: function code E; Tryptophan synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpA family [H]

Homologues:

Organism=Escherichia coli, GI1787514, Length=268, Percent_Identity=36.1940298507463, Blast_Score=156, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6321412, Length=249, Percent_Identity=40.5622489959839, Blast_Score=178, Evalue=1e-45,

Paralogues:

None

Copy number: 280 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011060
- InterPro:   IPR018204
- InterPro:   IPR002028 [H]

Pfam domain/function: PF00290 Trp_syntA [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 27978; Mature: 27847

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00167 TRP_SYNTHASE_ALPHA ; PS00287 CYSTATIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRIQNTFAALAAQGRKGLIPFITAGDPDPAKTVELMHALAEGGADVIELGVPFSDPMAD
CCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCC
GPVIQRSSERALAKGVTLHSVLDDVKRFRARDQKTPVVLMGYANPIERMGADAFAAAARD
CCCCCCCCHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHCCHHHHHHHHC
AGVDGVLVVDYPPEESHDFAAKMRAAGIDPIFLLAPTSTDDRIAAVGQVASGYVYYVSLK
CCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCEEEEEEEC
GVTGAANLDVSSIAGKIPAIKSRVPLPVGVGFGIRDAATARAVAEVADAVVIGSRLVQLL
CCCCCCCCCHHHHHCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EQAAPERAAAELAGFVAELRVAIDGAAKPAA
HHHCCHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SRIQNTFAALAAQGRKGLIPFITAGDPDPAKTVELMHALAEGGADVIELGVPFSDPMAD
CHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCC
GPVIQRSSERALAKGVTLHSVLDDVKRFRARDQKTPVVLMGYANPIERMGADAFAAAARD
CCCCCCCCHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHCCHHHHHHHHC
AGVDGVLVVDYPPEESHDFAAKMRAAGIDPIFLLAPTSTDDRIAAVGQVASGYVYYVSLK
CCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCEEEEEEEC
GVTGAANLDVSSIAGKIPAIKSRVPLPVGVGFGIRDAATARAVAEVADAVVIGSRLVQLL
CCCCCCCCCHHHHHCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EQAAPERAAAELAGFVAELRVAIDGAAKPAA
HHHCCHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA