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The map label for this gene is pcp [H]

Identifier: 53722583

GI number: 53722583

Start: 2120444

End: 2122033

Strand: Reverse

Name: pcp [H]

Synonym: BPSS1562

Alternate gene names: 53722583

Gene position: 2122033-2120444 (Counterclockwise)

Preceding gene: 53722584

Following gene: 53722582

Centisome position: 66.88

GC content: 71.89

Gene sequence:

>1590_bases
ATGGCAAGGCATCTTCACGCCGGCAACGAATCGCATCTCGTCGCCGAATCCACGTGCATCGGGCCGTGCGATCCGGCCGA
GACGATTCATGTAGTGGTGATGTTGCGGCGACAGCAAGAGCAGCACCTCGATTCATTGTTGCAGGGCCTCGCGAGCGGCG
ATCCGGGCGTGAAGCCTGTCTCGCGCGAGGCGTTCGCCCAGCGTTTCGGCGCGCATCCCGACGACGTCATGAAAGTCGAG
GCATTCGCGCAGCAGCGCGGCCTCGCGGTCGCGCGCGTCGATCCGGTCGAGAGCCTCGTCGTGCTGTCGGGCACGATCGC
GCAGTTCGAGGCGGCCTTCGGCGTGAAGCTCGAGCGCTTCGAGCATCGGTCGATCGGCCAGTATCGCGGCCGCACGGGCG
ATATCACGCTGCCCGACGAGTTGCACGGCATCGTCACCGCGGTGCTCGGGCTCGACGATCGCCCGCAGGCCCGGCCGCAT
TTCCGGCTGCGGCCGACTTTTCTGCCCGCGCGCGCGCCGGCCGTCACCTACACGCCGCCGCAGCTCGCGGCCCTCTACGA
TTTCCCGCCCGGCGACGGCGCGGGCCAGTGCATCGCGATCGTCGAGCTCGGCGGCGGCTATCGGCCGGCCGAGATCCAGC
AGTATTTCGGCGGCCTCGGGCTCGCGCGGCAGCCGAAGCTCGTCGACGTGAGCGTCGGCGCGGGGCGCAACGCGCCGACG
GGCGATCCGAGCGGGCCGGACGGCGAAGTCGCGCTCGATATCGAGATCGCGGGCGCGATCGCGCCCGGCGCGACGATTGC
CGTCTATTTCGCGCAGAACAGCGACGCCGGCTTCATCCAGGCGGTCAATCAGGCGGTGCACGACACGACGAACCGGCCCT
CCGTCGTGTCGATCAGTTGGGGCGCGGCGGAGGCGAACTGGACGTCGCAATCGATCCAGGCCTTCGATAGCGTGCTGCAG
TCGGCCGCGGCGCTCGGCGTGACCGTGTGCGCGGCGTCCGGCGATGACGGCTCGAACGACGGCCTGCAGGACGGCACGAA
TCACGTCGATTTCCCGGCATCGAGCCCGTACGTGCTCGCGTGCGGCGGCACGCGGCTCGACGCGCTGCCGGGGCAGGGCA
TCCGCAGCGAAGTCGTGTGGAACGACGAGGCGGCGGGCGGCGGCGCGACGGGCGGCGGCGTCAGCGCCGTGTTCGACGTG
CCGCAGTGGCAGAGCGGCCTGAGCGCGACGCTCGCGCAGGGTGGCGGCGCGTCGCCGCTCGCGAAGCGCGGCGTGCCGGA
CGTCGCGGGCGATGCGTCGCCCGCGACGGGCTACGAGGTGTTCGTCGCGGGCACGTCGACGGTGATGGGCGGCACGAGCG
CCGTCGCACCGCTGTGGGCCGCGCTCGTCGCGCGGATCAATGCGGCGGCGGGCAGCCCCGCGGGCTGGATCAACCCGAAG
CTGTACCGGAACGCGGGCGCGCTGCACGACATCTCGGTGGGCGATAACGGCGCGTATGCGGCGACGCCGGGCTGGGACGC
GTGCACGGGGCTCGGCAGCCCGGACGGCGCGAAGGTCGCGGCGGCGCTGAAAGGCGGCGCGGCGGGCTGA

Upstream 100 bases:

>100_bases
CGGCGTGTGTGCGCCGTCCGACATACCGCCCGGAACTGCGATCGCGCGACCGTGTCCGAATCCTGGCAATCCGTCACCAC
GGCTTCTGGAGGGTCCGAAT

Downstream 100 bases:

>100_bases
TTGACGGCAAGCCGAGGCGACGGTGCGCGGCAGCTTGCACGCCGCGCCTGGGCGCCGCCGCGGCCGCGGGCGCGCGCATC
GAATGCGGCGGCGCGCAGGT

Product: kumamolisin

Products: NA

Alternate protein names: Pepstatin-insensitive carboxyl proteinase; Pseudomonapepsin [H]

Number of amino acids: Translated: 529; Mature: 528

Protein sequence:

>529_residues
MARHLHAGNESHLVAESTCIGPCDPAETIHVVVMLRRQQEQHLDSLLQGLASGDPGVKPVSREAFAQRFGAHPDDVMKVE
AFAQQRGLAVARVDPVESLVVLSGTIAQFEAAFGVKLERFEHRSIGQYRGRTGDITLPDELHGIVTAVLGLDDRPQARPH
FRLRPTFLPARAPAVTYTPPQLAALYDFPPGDGAGQCIAIVELGGGYRPAEIQQYFGGLGLARQPKLVDVSVGAGRNAPT
GDPSGPDGEVALDIEIAGAIAPGATIAVYFAQNSDAGFIQAVNQAVHDTTNRPSVVSISWGAAEANWTSQSIQAFDSVLQ
SAAALGVTVCAASGDDGSNDGLQDGTNHVDFPASSPYVLACGGTRLDALPGQGIRSEVVWNDEAAGGGATGGGVSAVFDV
PQWQSGLSATLAQGGGASPLAKRGVPDVAGDASPATGYEVFVAGTSTVMGGTSAVAPLWAALVARINAAAGSPAGWINPK
LYRNAGALHDISVGDNGAYAATPGWDACTGLGSPDGAKVAAALKGGAAG

Sequences:

>Translated_529_residues
MARHLHAGNESHLVAESTCIGPCDPAETIHVVVMLRRQQEQHLDSLLQGLASGDPGVKPVSREAFAQRFGAHPDDVMKVE
AFAQQRGLAVARVDPVESLVVLSGTIAQFEAAFGVKLERFEHRSIGQYRGRTGDITLPDELHGIVTAVLGLDDRPQARPH
FRLRPTFLPARAPAVTYTPPQLAALYDFPPGDGAGQCIAIVELGGGYRPAEIQQYFGGLGLARQPKLVDVSVGAGRNAPT
GDPSGPDGEVALDIEIAGAIAPGATIAVYFAQNSDAGFIQAVNQAVHDTTNRPSVVSISWGAAEANWTSQSIQAFDSVLQ
SAAALGVTVCAASGDDGSNDGLQDGTNHVDFPASSPYVLACGGTRLDALPGQGIRSEVVWNDEAAGGGATGGGVSAVFDV
PQWQSGLSATLAQGGGASPLAKRGVPDVAGDASPATGYEVFVAGTSTVMGGTSAVAPLWAALVARINAAAGSPAGWINPK
LYRNAGALHDISVGDNGAYAATPGWDACTGLGSPDGAKVAAALKGGAAG
>Mature_528_residues
ARHLHAGNESHLVAESTCIGPCDPAETIHVVVMLRRQQEQHLDSLLQGLASGDPGVKPVSREAFAQRFGAHPDDVMKVEA
FAQQRGLAVARVDPVESLVVLSGTIAQFEAAFGVKLERFEHRSIGQYRGRTGDITLPDELHGIVTAVLGLDDRPQARPHF
RLRPTFLPARAPAVTYTPPQLAALYDFPPGDGAGQCIAIVELGGGYRPAEIQQYFGGLGLARQPKLVDVSVGAGRNAPTG
DPSGPDGEVALDIEIAGAIAPGATIAVYFAQNSDAGFIQAVNQAVHDTTNRPSVVSISWGAAEANWTSQSIQAFDSVLQS
AAALGVTVCAASGDDGSNDGLQDGTNHVDFPASSPYVLACGGTRLDALPGQGIRSEVVWNDEAAGGGATGGGVSAVFDVP
QWQSGLSATLAQGGGASPLAKRGVPDVAGDASPATGYEVFVAGTSTVMGGTSAVAPLWAALVARINAAAGSPAGWINPKL
YRNAGALHDISVGDNGAYAATPGWDACTGLGSPDGAKVAAALKGGAAG

Specific function: Unknown

COG id: COG4934

COG function: function code O; Predicted protease

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S53 family [H]

Homologues:

Organism=Homo sapiens, GI5729770, Length=566, Percent_Identity=26.3250883392226, Blast_Score=86, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015366
- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR009020 [H]

Pfam domain/function: PF00082 Peptidase_S8; PF09286 Pro-kuma_activ [H]

EC number: =3.4.21.100 [H]

Molecular weight: Translated: 53967; Mature: 53835

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARHLHAGNESHLVAESTCIGPCDPAETIHVVVMLRRQQEQHLDSLLQGLASGDPGVKPV
CCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SREAFAQRFGAHPDDVMKVEAFAQQRGLAVARVDPVESLVVLSGTIAQFEAAFGVKLERF
CHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHCHHHHHHHHHCCCHHHH
EHRSIGQYRGRTGDITLPDELHGIVTAVLGLDDRPQARPHFRLRPTFLPARAPAVTYTPP
HHHCHHHHCCCCCCEECCHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCEEEECCC
QLAALYDFPPGDGAGQCIAIVELGGGYRPAEIQQYFGGLGLARQPKLVDVSVGAGRNAPT
CCEEEEECCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCC
GDPSGPDGEVALDIEIAGAIAPGATIAVYFAQNSDAGFIQAVNQAVHDTTNRPSVVSISW
CCCCCCCCCEEEEEEEECEECCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEC
GAAEANWTSQSIQAFDSVLQSAAALGVTVCAASGDDGSNDGLQDGTNHVDFPASSPYVLA
CCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEE
CGGTRLDALPGQGIRSEVVWNDEAAGGGATGGGVSAVFDVPQWQSGLSATLAQGGGASPL
ECCCEECCCCCCCCCCCEEECCCCCCCCCCCCCCEEEEECCCHHCCHHHHHHCCCCCCCH
AKRGVPDVAGDASPATGYEVFVAGTSTVMGGTSAVAPLWAALVARINAAAGSPAGWINPK
HHCCCCCCCCCCCCCCCEEEEEEECCEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCH
LYRNAGALHDISVGDNGAYAATPGWDACTGLGSPDGAKVAAALKGGAAG
HHHCCCCEEEEECCCCCCEECCCCCHHHCCCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure 
ARHLHAGNESHLVAESTCIGPCDPAETIHVVVMLRRQQEQHLDSLLQGLASGDPGVKPV
CCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SREAFAQRFGAHPDDVMKVEAFAQQRGLAVARVDPVESLVVLSGTIAQFEAAFGVKLERF
CHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHCHHHHHHHHHCCCHHHH
EHRSIGQYRGRTGDITLPDELHGIVTAVLGLDDRPQARPHFRLRPTFLPARAPAVTYTPP
HHHCHHHHCCCCCCEECCHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCEEEECCC
QLAALYDFPPGDGAGQCIAIVELGGGYRPAEIQQYFGGLGLARQPKLVDVSVGAGRNAPT
CCEEEEECCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCC
GDPSGPDGEVALDIEIAGAIAPGATIAVYFAQNSDAGFIQAVNQAVHDTTNRPSVVSISW
CCCCCCCCCEEEEEEEECEECCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEC
GAAEANWTSQSIQAFDSVLQSAAALGVTVCAASGDDGSNDGLQDGTNHVDFPASSPYVLA
CCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEE
CGGTRLDALPGQGIRSEVVWNDEAAGGGATGGGVSAVFDVPQWQSGLSATLAQGGGASPL
ECCCEECCCCCCCCCCCEEECCCCCCCCCCCCCCEEEEECCCHHCCHHHHHHCCCCCCCH
AKRGVPDVAGDASPATGYEVFVAGTSTVMGGTSAVAPLWAALVARINAAAGSPAGWINPK
HHCCCCCCCCCCCCCCCEEEEEEECCEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCH
LYRNAGALHDISVGDNGAYAATPGWDACTGLGSPDGAKVAAALKGGAAG
HHHCCCCEEEEECCCCCCEECCCCCHHHCCCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7929375; 8576087; 10488127; 11747435; 11323721 [H]