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The map label for this gene is dhbF [H]

Identifier: 53722288

GI number: 53722288

Start: 1716573

End: 1719788

Strand: Reverse

Name: dhbF [H]

Synonym: BPSS1266

Alternate gene names: 53722288

Gene position: 1719788-1716573 (Counterclockwise)

Preceding gene: 53722289

Following gene: 53722283

Centisome position: 54.2

GC content: 73.01

Gene sequence:

>3216_bases
ATGAACATGCGCGATACATCGCTTCGCCCGCTGCTGCCCGCCCAGCGGGAGATCTGGCTCGCCGAGCAGTTGCGCCCGGG
CACGGGTGTCTACAACACGGCGGGCTACGCCGACATCGTCGGCGCCGTCGATCACGGCGCGCTGCGGGACGCGTTCGGCC
ACGCGATGCGCGAGGCCGACGCCGCGCGCGCGACGTTCTCCGCGCACGGCGACGACGCGTGGCAGACGCCGCGCGATGCG
CCGCACGCCGACGTGCCGCTCGTCGACGTGAGCGGCCAGGCCGATCCCGCCGGCGTCGCGCTCGCATGGATGATGCGCGA
CATGCGCACGCCGCCCGATTTCGCGGCGGGCCCGCTGGTACGCAGCGCGCTCTTGCGGGTGGGGGCGGCGCGCTTTTTCT
GGTACGTCTGCGCGCATCACATCGTCACCGACGCGTACGGCACGGCGCTCGTCGTGCAACGCACGGCGCAGCTCTACGGC
GCGCGGGTGCGCGGCGCGGCGCCGCCGCCCGCGTGGTTCGGCACGCTGGACGCGCTCATCGACGAGGACCGCGCGTATCG
CGAATCGGCCGCGTTCGCCGACGATCGCGATTACTGGCGCGCCCGCCTGGCGGCGGCGCCGGAGCCGCGCAGCCTGTCGC
CCGTCGCGCTGCCGGGGCAGTTCGCGCCGGCCGGCGACTTTCACCGGCAATGGGGCGAGCTCGACGCCGCGACGAGCGAC
GGGCTGCGCGCGATGGCGCGCGCCGGCGCACAAGGCATGCCGCCGCTCGTCGCGGCGATGATGGCCGCCTATGTGCATCG
GTTCACGCACGAGCGCGACGTCGTGCTCGGCTTGCCCGTCATGGCGCGGCTAAGCCGCGCCACGCGCAGGACGCCGGGCA
TGGTCGCGAACGTGCTGCCGCTGCGCTTCGCGTTCGATCGCGGGACGACGTTCGCGGCGCTCCACGCGCAATGCGCGGCC
GAGATGCGCGCGTCGCTGCGGCACCAGCGCTATCGCGGCGAGGCGATGCTGCGCGATGCGCAGCAGCGCCGGCCGGCCGA
GCGCCTTCACGCGCAGAACGTGAACGTGATGGCGTTCGAGCGGGCGCTCGCGTTCGGCGATTGCCCGGCGCGCTCGCACA
GCCTGTCGAACGGCCCCGTCGACGATTTTTCGATCACCGTCTACGACGACGGCGCGAGGCAACCGATCCGCATCGCGTTC
GACGCGAACGCGGCGCGCTATGCAAGCGGCGATCTGGCCGCGCATCGCGAGCGCTTTCTGCGCCTTGGCGTCGCGCTCGC
GAACGCGGCGCAGCGGCCGATCGCCGACGCGCAGTGGCTCACGCCCGCCGAGCGCCGGACGCTGGTCGGCGAACGCGGCA
CGCCCGCGCCGGATGCGGGCGAGCCCTTCGACACCATCGCCGCGCGCTTCGCGGCGCGGGCCGCCGAGCGCCCGGACGCG
ATCGCGCTCGTCGATCGCGGGCGGCGGATCACGTACGGCGAGCTGAACGCGCGCGCGAATCGGCTCGCGCACGTGCTGAT
CGAGGCGGGCGTCGGGCCGGAGGCGCTGGTCGGCCTGCACATGCCGCGCTCGGCCGAGCTCGTCGTCGGCATGCTCGCGA
TATTGAAGGCGGGCGGCGCGTACGTGCCGCTCGACCCCGCCTATCCGGCCTCGCGCATCGAATTCATGGTGGCCGACGCG
CGGCCGATGCTGTCGATCACGACGGGCGAGCACGCGGCGCAACTGCCGGCCCGCACGCCGACGATCGTGCTCGACGCCGC
CGACGCGCAGGCGGCGTTGCGGCGCGCGCCCGCGCACGACCCGGTGCGGCCGGCGCCGCTCGATCGCGAGCACGCGGCGT
ACGTGATCTATACGTCCGGCTCCACCGGCAAGCCGAAGGGCGCGGTGGTGTCGCACCGCAACGTGATCCGCCTGCTGGAC
GGCACGCGCGGCTGGTTCGATTTCGGCGCGGCGCATACGTGGACGCTGTTCCATTCGTTCGCATTCGATTTCTCGGTGTG
GGAGTGCTGGGGCGCGCTGCTCACGGGCGGGCGGCTCGTCGTCGTGCCTTACGACGTGAGCCGCTCGCCCGCCGAGTTCC
TGAAGCTGCTGGTCGACGAGCGCGTGACGGTGCTCAATCAGACGCCGTCGGCGTTTCGCCAGCTGATGCAGGCCGACGAG
GCGCACGCGGACTTGAGCGCGCGGCTCGCGCTGCGCTACGTGGTGTTCGGCGGCGAGGCGCTCGACGCGCGCAGCCTCGC
GCGCTGGTATGAGCGGCACGCGGACACCGCGCCCCGGCTCGTCAACATGTACGGCATCACCGAGACGACGGTCCACGTCA
GCTATCTGGCGCTCAGCCGCGCGATCGCCGGGATGCCGGCGAACAGCCTGATCGGCCGGCCGCTTCCCGACTTGCGCGTG
TATGTGCTCGACGCCGCGCTGCGCCCCGTGCCGGCGGGCGTGCCGGGCGAGATGTACGTCGCCGGCGCGGGGCTCGCGCG
CGGCTATCTGCGCCGGCCGTCGCTCACCGCGCAGCGCTTCATCGCCGATCCGTTCGGGCCGCCGGGCACGCGCATGTACC
GCACGGGCGACGTCGCGCGATGGCGGGCCGACGGCGGGCTCGATTTCATCGGGCGGGCCGACGAGCAGGTGAAAGTGCGC
GGCTTTCGCGTGGAGCTCGGCGAAATCGCCGCGCGGCTCGCGTGCGATCCGTCGGTCGCGCAGGCGCAGGCTGTCGTGCG
GCAGGACGGGCCTGCGCACGAGCGGCTCGTCGCGTACGTCGTGCCGCGCGCCGGCGCGACGATCGACGTTTGCGCGCTGC
GCGCGTCGCTCGCGGCCGAGATGCCGGAATACATGGTGCCCGCGGCCATCGTCGCGCTCGATGCGATGCCGCTCACGCCG
AACGGCAAACTCGACCGCGCGGCGCTGCCGGCGCCGATCGTGACGGGCACGAGCCGGCGCGCGCCGGAAAACCGCATCGA
GCAGCAGGTGTGCGCGATGTTCGCGGAACTGCTCGATGCGCAGACGCTCGGCGCCGAGGACAATTTTTTCGAGCTCGGCG
GCGATTCGCTGCTGGCGATGCGCGCGATCAACAAGCTGCGGCAGACGTTCGATGTCGAGCTGACGATTCGCGATCTGTTT
TCCGCGCCGACTGTCGCGGCGCTCAGCATGCGGCTCGATGCGCAATTGGCGGCGCGCCGCGCTCACGCGGACGGCGCTGA
GCTGCCCGCCGGGTAG

Upstream 100 bases:

>100_bases
GTCGCCGCCCGATGCGCGTGAGCGCCGCGGCGTTCGCCATTCCCGGGTGCGCGCCGTCGCGGCCCGCATGCAGCATATCG
ACACAGGACTTCGCCTCGCC

Downstream 100 bases:

>100_bases
GCGGCGCGCCGCGCCGGTCTCCGGGGGCGAGGCGGCCGGAATGCGTCGGCGCGAACGCGCGGGCAGGCGGGCGTCGCGCG
GAGCATCGGCTTTGCCGTGG

Product: peptide/siderophore synthetase

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: NA

Number of amino acids: Translated: 1071; Mature: 1071

Protein sequence:

>1071_residues
MNMRDTSLRPLLPAQREIWLAEQLRPGTGVYNTAGYADIVGAVDHGALRDAFGHAMREADAARATFSAHGDDAWQTPRDA
PHADVPLVDVSGQADPAGVALAWMMRDMRTPPDFAAGPLVRSALLRVGAARFFWYVCAHHIVTDAYGTALVVQRTAQLYG
ARVRGAAPPPAWFGTLDALIDEDRAYRESAAFADDRDYWRARLAAAPEPRSLSPVALPGQFAPAGDFHRQWGELDAATSD
GLRAMARAGAQGMPPLVAAMMAAYVHRFTHERDVVLGLPVMARLSRATRRTPGMVANVLPLRFAFDRGTTFAALHAQCAA
EMRASLRHQRYRGEAMLRDAQQRRPAERLHAQNVNVMAFERALAFGDCPARSHSLSNGPVDDFSITVYDDGARQPIRIAF
DANAARYASGDLAAHRERFLRLGVALANAAQRPIADAQWLTPAERRTLVGERGTPAPDAGEPFDTIAARFAARAAERPDA
IALVDRGRRITYGELNARANRLAHVLIEAGVGPEALVGLHMPRSAELVVGMLAILKAGGAYVPLDPAYPASRIEFMVADA
RPMLSITTGEHAAQLPARTPTIVLDAADAQAALRRAPAHDPVRPAPLDREHAAYVIYTSGSTGKPKGAVVSHRNVIRLLD
GTRGWFDFGAAHTWTLFHSFAFDFSVWECWGALLTGGRLVVVPYDVSRSPAEFLKLLVDERVTVLNQTPSAFRQLMQADE
AHADLSARLALRYVVFGGEALDARSLARWYERHADTAPRLVNMYGITETTVHVSYLALSRAIAGMPANSLIGRPLPDLRV
YVLDAALRPVPAGVPGEMYVAGAGLARGYLRRPSLTAQRFIADPFGPPGTRMYRTGDVARWRADGGLDFIGRADEQVKVR
GFRVELGEIAARLACDPSVAQAQAVVRQDGPAHERLVAYVVPRAGATIDVCALRASLAAEMPEYMVPAAIVALDAMPLTP
NGKLDRAALPAPIVTGTSRRAPENRIEQQVCAMFAELLDAQTLGAEDNFFELGGDSLLAMRAINKLRQTFDVELTIRDLF
SAPTVAALSMRLDAQLAARRAHADGAELPAG

Sequences:

>Translated_1071_residues
MNMRDTSLRPLLPAQREIWLAEQLRPGTGVYNTAGYADIVGAVDHGALRDAFGHAMREADAARATFSAHGDDAWQTPRDA
PHADVPLVDVSGQADPAGVALAWMMRDMRTPPDFAAGPLVRSALLRVGAARFFWYVCAHHIVTDAYGTALVVQRTAQLYG
ARVRGAAPPPAWFGTLDALIDEDRAYRESAAFADDRDYWRARLAAAPEPRSLSPVALPGQFAPAGDFHRQWGELDAATSD
GLRAMARAGAQGMPPLVAAMMAAYVHRFTHERDVVLGLPVMARLSRATRRTPGMVANVLPLRFAFDRGTTFAALHAQCAA
EMRASLRHQRYRGEAMLRDAQQRRPAERLHAQNVNVMAFERALAFGDCPARSHSLSNGPVDDFSITVYDDGARQPIRIAF
DANAARYASGDLAAHRERFLRLGVALANAAQRPIADAQWLTPAERRTLVGERGTPAPDAGEPFDTIAARFAARAAERPDA
IALVDRGRRITYGELNARANRLAHVLIEAGVGPEALVGLHMPRSAELVVGMLAILKAGGAYVPLDPAYPASRIEFMVADA
RPMLSITTGEHAAQLPARTPTIVLDAADAQAALRRAPAHDPVRPAPLDREHAAYVIYTSGSTGKPKGAVVSHRNVIRLLD
GTRGWFDFGAAHTWTLFHSFAFDFSVWECWGALLTGGRLVVVPYDVSRSPAEFLKLLVDERVTVLNQTPSAFRQLMQADE
AHADLSARLALRYVVFGGEALDARSLARWYERHADTAPRLVNMYGITETTVHVSYLALSRAIAGMPANSLIGRPLPDLRV
YVLDAALRPVPAGVPGEMYVAGAGLARGYLRRPSLTAQRFIADPFGPPGTRMYRTGDVARWRADGGLDFIGRADEQVKVR
GFRVELGEIAARLACDPSVAQAQAVVRQDGPAHERLVAYVVPRAGATIDVCALRASLAAEMPEYMVPAAIVALDAMPLTP
NGKLDRAALPAPIVTGTSRRAPENRIEQQVCAMFAELLDAQTLGAEDNFFELGGDSLLAMRAINKLRQTFDVELTIRDLF
SAPTVAALSMRLDAQLAARRAHADGAELPAG
>Mature_1071_residues
MNMRDTSLRPLLPAQREIWLAEQLRPGTGVYNTAGYADIVGAVDHGALRDAFGHAMREADAARATFSAHGDDAWQTPRDA
PHADVPLVDVSGQADPAGVALAWMMRDMRTPPDFAAGPLVRSALLRVGAARFFWYVCAHHIVTDAYGTALVVQRTAQLYG
ARVRGAAPPPAWFGTLDALIDEDRAYRESAAFADDRDYWRARLAAAPEPRSLSPVALPGQFAPAGDFHRQWGELDAATSD
GLRAMARAGAQGMPPLVAAMMAAYVHRFTHERDVVLGLPVMARLSRATRRTPGMVANVLPLRFAFDRGTTFAALHAQCAA
EMRASLRHQRYRGEAMLRDAQQRRPAERLHAQNVNVMAFERALAFGDCPARSHSLSNGPVDDFSITVYDDGARQPIRIAF
DANAARYASGDLAAHRERFLRLGVALANAAQRPIADAQWLTPAERRTLVGERGTPAPDAGEPFDTIAARFAARAAERPDA
IALVDRGRRITYGELNARANRLAHVLIEAGVGPEALVGLHMPRSAELVVGMLAILKAGGAYVPLDPAYPASRIEFMVADA
RPMLSITTGEHAAQLPARTPTIVLDAADAQAALRRAPAHDPVRPAPLDREHAAYVIYTSGSTGKPKGAVVSHRNVIRLLD
GTRGWFDFGAAHTWTLFHSFAFDFSVWECWGALLTGGRLVVVPYDVSRSPAEFLKLLVDERVTVLNQTPSAFRQLMQADE
AHADLSARLALRYVVFGGEALDARSLARWYERHADTAPRLVNMYGITETTVHVSYLALSRAIAGMPANSLIGRPLPDLRV
YVLDAALRPVPAGVPGEMYVAGAGLARGYLRRPSLTAQRFIADPFGPPGTRMYRTGDVARWRADGGLDFIGRADEQVKVR
GFRVELGEIAARLACDPSVAQAQAVVRQDGPAHERLVAYVVPRAGATIDVCALRASLAAEMPEYMVPAAIVALDAMPLTP
NGKLDRAALPAPIVTGTSRRAPENRIEQQVCAMFAELLDAQTLGAEDNFFELGGDSLLAMRAINKLRQTFDVELTIRDLF
SAPTVAALSMRLDAQLAARRAHADGAELPAG

Specific function: Specifically adenylates threonine and glycine, and loads them onto their corresponding peptidyl carrier domains [H]

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=434, Percent_Identity=26.4976958525346, Blast_Score=124, Evalue=4e-28,
Organism=Homo sapiens, GI187761345, Length=600, Percent_Identity=26.3333333333333, Blast_Score=120, Evalue=5e-27,
Organism=Homo sapiens, GI187761343, Length=600, Percent_Identity=26.3333333333333, Blast_Score=120, Evalue=5e-27,
Organism=Homo sapiens, GI13375727, Length=568, Percent_Identity=22.1830985915493, Blast_Score=93, Evalue=1e-18,
Organism=Homo sapiens, GI38505220, Length=522, Percent_Identity=25.6704980842912, Blast_Score=89, Evalue=3e-17,
Organism=Homo sapiens, GI42544132, Length=526, Percent_Identity=21.8631178707224, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI122937307, Length=534, Percent_Identity=23.0337078651685, Blast_Score=77, Evalue=6e-14,
Organism=Homo sapiens, GI157311624, Length=517, Percent_Identity=21.8568665377176, Blast_Score=73, Evalue=2e-12,
Organism=Homo sapiens, GI157311622, Length=517, Percent_Identity=21.8568665377176, Blast_Score=73, Evalue=2e-12,
Organism=Escherichia coli, GI1786801, Length=1068, Percent_Identity=34.3632958801498, Blast_Score=477, Evalue=1e-135,
Organism=Escherichia coli, GI1786810, Length=542, Percent_Identity=26.5682656826568, Blast_Score=112, Evalue=2e-25,
Organism=Escherichia coli, GI145693145, Length=543, Percent_Identity=23.9410681399632, Blast_Score=105, Evalue=2e-23,
Organism=Escherichia coli, GI1788107, Length=555, Percent_Identity=24.6846846846847, Blast_Score=101, Evalue=3e-22,
Organism=Escherichia coli, GI221142682, Length=511, Percent_Identity=24.6575342465753, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1789201, Length=379, Percent_Identity=28.7598944591029, Blast_Score=93, Evalue=8e-20,
Organism=Escherichia coli, GI1790505, Length=536, Percent_Identity=22.5746268656716, Blast_Score=93, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17556356, Length=524, Percent_Identity=26.7175572519084, Blast_Score=128, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17558820, Length=502, Percent_Identity=23.5059760956175, Blast_Score=103, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17550940, Length=450, Percent_Identity=24.2222222222222, Blast_Score=99, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI32563687, Length=509, Percent_Identity=22.7897838899804, Blast_Score=99, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17560308, Length=363, Percent_Identity=25.6198347107438, Blast_Score=74, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6319591, Length=900, Percent_Identity=23.7777777777778, Blast_Score=217, Evalue=9e-57,
Organism=Saccharomyces cerevisiae, GI6319264, Length=534, Percent_Identity=23.7827715355805, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24648676, Length=577, Percent_Identity=31.369150779896, Blast_Score=236, Evalue=7e-62,
Organism=Drosophila melanogaster, GI24581924, Length=551, Percent_Identity=25.5898366606171, Blast_Score=120, Evalue=4e-27,
Organism=Drosophila melanogaster, GI62472339, Length=592, Percent_Identity=23.6486486486486, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24582852, Length=533, Percent_Identity=23.827392120075, Blast_Score=91, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24667955, Length=568, Percent_Identity=23.5915492957746, Blast_Score=91, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24667959, Length=408, Percent_Identity=25.2450980392157, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI18859661, Length=529, Percent_Identity=21.7391304347826, Blast_Score=78, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 115951; Mature: 115951

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMRDTSLRPLLPAQREIWLAEQLRPGTGVYNTAGYADIVGAVDHGALRDAFGHAMREAD
CCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHH
AARATFSAHGDDAWQTPRDAPHADVPLVDVSGQADPAGVALAWMMRDMRTPPDFAAGPLV
HHHHEECCCCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCCCHHHHH
RSALLRVGAARFFWYVCAHHIVTDAYGTALVVQRTAQLYGARVRGAAPPPAWFGTLDALI
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHCCCCCCCCHHHHHHHHHH
DEDRAYRESAAFADDRDYWRARLAAAPEPRSLSPVALPGQFAPAGDFHRQWGELDAATSD
HHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCEECCCCCCCCCHHHHHHCCCCCCCHH
GLRAMARAGAQGMPPLVAAMMAAYVHRFTHERDVVLGLPVMARLSRATRRTPGMVANVLP
HHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHCCCCCHHHHHHH
LRFAFDRGTTFAALHAQCAAEMRASLRHQRYRGEAMLRDAQQRRPAERLHAQNVNVMAFE
HEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEHH
RALAFGDCPARSHSLSNGPVDDFSITVYDDGARQPIRIAFDANAARYASGDLAAHRERFL
HHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHH
RLGVALANAAQRPIADAQWLTPAERRTLVGERGTPAPDAGEPFDTIAARFAARAAERPDA
HHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCE
IALVDRGRRITYGELNARANRLAHVLIEAGVGPEALVGLHMPRSAELVVGMLAILKAGGA
EEEECCCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHEEECCCCHHHHHHHHHHHHHCCCC
YVPLDPAYPASRIEFMVADARPMLSITTGEHAAQLPARTPTIVLDAADAQAALRRAPAHD
EECCCCCCCHHHEEEEEECCCCEEEEECCCHHHHCCCCCCEEEEECCHHHHHHHHCCCCC
PVRPAPLDREHAAYVIYTSGSTGKPKGAVVSHRNVIRLLDGTRGWFDFGAAHTWTLFHSF
CCCCCCCCCCCCEEEEEECCCCCCCCCCEECCCCEEEECCCCCCHHHCCCHHHHHHHHHH
AFDFSVWECWGALLTGGRLVVVPYDVSRSPAEFLKLLVDERVTVLNQTPSAFRQLMQADE
HHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AHADLSARLALRYVVFGGEALDARSLARWYERHADTAPRLVNMYGITETTVHVSYLALSR
HHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHH
AIAGMPANSLIGRPLPDLRVYVLDAALRPVPAGVPGEMYVAGAGLARGYLRRPSLTAQRF
HHHCCCCHHHCCCCCCHHEEEEEHHHHCCCCCCCCCCEEEECCHHHHHHHCCCCHHHHHH
IADPFGPPGTRMYRTGDVARWRADGGLDFIGRADEQVKVRGFRVELGEIAARLACDPSVA
HCCCCCCCCCCEEECCCCEEEECCCCCCCCCCCCCEEEEEEEEEEHHHHHHHHCCCCHHH
QAQAVVRQDGPAHERLVAYVVPRAGATIDVCALRASLAAEMPEYMVPAAIVALDAMPLTP
HHHHHHHCCCCHHHEEEEEEECCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCC
NGKLDRAALPAPIVTGTSRRAPENRIEQQVCAMFAELLDAQTLGAEDNFFELGGDSLLAM
CCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHH
RAINKLRQTFDVELTIRDLFSAPTVAALSMRLDAQLAARRAHADGAELPAG
HHHHHHHHHHHHEEEHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNMRDTSLRPLLPAQREIWLAEQLRPGTGVYNTAGYADIVGAVDHGALRDAFGHAMREAD
CCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHH
AARATFSAHGDDAWQTPRDAPHADVPLVDVSGQADPAGVALAWMMRDMRTPPDFAAGPLV
HHHHEECCCCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCCCHHHHH
RSALLRVGAARFFWYVCAHHIVTDAYGTALVVQRTAQLYGARVRGAAPPPAWFGTLDALI
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHCCCCCCCCHHHHHHHHHH
DEDRAYRESAAFADDRDYWRARLAAAPEPRSLSPVALPGQFAPAGDFHRQWGELDAATSD
HHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCEECCCCCCCCCHHHHHHCCCCCCCHH
GLRAMARAGAQGMPPLVAAMMAAYVHRFTHERDVVLGLPVMARLSRATRRTPGMVANVLP
HHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHCCCCCHHHHHHH
LRFAFDRGTTFAALHAQCAAEMRASLRHQRYRGEAMLRDAQQRRPAERLHAQNVNVMAFE
HEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEHH
RALAFGDCPARSHSLSNGPVDDFSITVYDDGARQPIRIAFDANAARYASGDLAAHRERFL
HHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHH
RLGVALANAAQRPIADAQWLTPAERRTLVGERGTPAPDAGEPFDTIAARFAARAAERPDA
HHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCE
IALVDRGRRITYGELNARANRLAHVLIEAGVGPEALVGLHMPRSAELVVGMLAILKAGGA
EEEECCCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHEEECCCCHHHHHHHHHHHHHCCCC
YVPLDPAYPASRIEFMVADARPMLSITTGEHAAQLPARTPTIVLDAADAQAALRRAPAHD
EECCCCCCCHHHEEEEEECCCCEEEEECCCHHHHCCCCCCEEEEECCHHHHHHHHCCCCC
PVRPAPLDREHAAYVIYTSGSTGKPKGAVVSHRNVIRLLDGTRGWFDFGAAHTWTLFHSF
CCCCCCCCCCCCEEEEEECCCCCCCCCCEECCCCEEEECCCCCCHHHCCCHHHHHHHHHH
AFDFSVWECWGALLTGGRLVVVPYDVSRSPAEFLKLLVDERVTVLNQTPSAFRQLMQADE
HHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AHADLSARLALRYVVFGGEALDARSLARWYERHADTAPRLVNMYGITETTVHVSYLALSR
HHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHH
AIAGMPANSLIGRPLPDLRVYVLDAALRPVPAGVPGEMYVAGAGLARGYLRRPSLTAQRF
HHHCCCCHHHCCCCCCHHEEEEEHHHHCCCCCCCCCCEEEECCHHHHHHHCCCCHHHHHH
IADPFGPPGTRMYRTGDVARWRADGGLDFIGRADEQVKVRGFRVELGEIAARLACDPSVA
HCCCCCCCCCCEEECCCCEEEECCCCCCCCCCCCCEEEEEEEEEEHHHHHHHHCCCCHHH
QAQAVVRQDGPAHERLVAYVVPRAGATIDVCALRASLAAEMPEYMVPAAIVALDAMPLTP
HHHHHHHCCCCHHHEEEEEEECCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCC
NGKLDRAALPAPIVTGTSRRAPENRIEQQVCAMFAELLDAQTLGAEDNFFELGGDSLLAM
CCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHH
RAINKLRQTFDVELTIRDLFSAPTVAALSMRLDAQLAARRAHADGAELPAG
HHHHHHHHHHHHEEEHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11112781; 9384377; 10568751; 8550523 [H]