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The map label for this gene is tycC [H]

Identifier: 53722219

GI number: 53722219

Start: 1605305

End: 1607986

Strand: Reverse

Name: tycC [H]

Synonym: BPSS1194

Alternate gene names: 53722219

Gene position: 1607986-1605305 (Counterclockwise)

Preceding gene: 53722220

Following gene: 53722218

Centisome position: 50.68

GC content: 75.5

Gene sequence:

>2682_bases
GTGCCCCCGGCCCCCCCCCGGGCGCCCGATAGGCTCCCCGTGCAGGAGGCCCCCCCCCGCCTGACGGCGCCGGCTCGCGA
GCGCCCCGTTCGCGCGCTCCCGGCACGCGCTGCCGGCGGCGGGCGTCGCGGCGCAAACGCTTGTCGCGATGCATCTGCCG
CCCGCCCCGGCGCTCGTGACGGCGATGCTCCCCGTGATGCGGGCGGCAGGCGTTCCCCCACCAATACCGCCGAGCTGCCC
GCCGCGCGCCGGCGTTACATGCTCGAGGACAGCGGCGCGCGGATCGTGCTGACGCTGCCGGACGCCGCGGACGATCTGCC
GCGGGATCTCGCGCTCGTGTGCGTGTACCCGGGGGAGGCCGATGTCGATGTCAACATCGACGCGCGCACGGCGGCATCCG
GACCGACCGCGCGCGTCACGGCCGACGCGCCTGCCGACGCGGGCGCGGACGCGACGACCGGCGCTTGCCCCGACGCGTGG
CCTGCCCCCGACCCGACGCAGGCCGCCTACGTGCTGTACACGTCCGGCTCGACGGGGCGGCCGAAAGGCGTCGTGGTCAC
GCACGGCTCGCTCGCGAACCACATGGCGTGGATGACGCGCGCGTTCCCGCTCGACGCGCACGACGCGGTGCTGCAAAAGA
CCTCGGCCGCGTTCGACGCGTCGATCTGGGAATTCTTCCTGCCGCTGCTGGCGGGCGCGCGGCTCGTGATGGCGCCGCCC
GGCCTCGAGCGCGACGTGCCGGCGCTCGTCGCGACGCTCGCGCGCGAGCGCATCACCGTGCTGCAGCTCGTGCCGAGCCT
GCTGCGCGTGCTCGTCGACGCGCCGGGCTTCGGCGCGTGCGACGCGCTGCGATGCGTGTTCTGCGGCGGCGAAGCGCTGA
CGGCCGATCTCGCCCGGCGCTTCGCCGCCGCGCACCGCGCGGCGCTCGTCAACCTGTACGGCCCGACCGAGACGACGATC
CAGGTTTGCGCGGAGCGGGTCGACGCGGCCGACGATCCCGTGCCGGTCGGCCGCCCGATCGACAACGTCCGGCTGTACGT
CGTCGATTCGCGCAACCGGCTCTCGCCCGTGGGCGTGCGCGGCGAGATCCTGATCGGCGGCGCGGCGCCCGCGCGCGGCT
ATCTCGATCGGCCGGCGCTCACCGCCGCGCGCTTCGTCGCCGATCCGATCGATCCGCGCGCGCCGCGCGTCTATCGCAGC
GGCGACGTGGGCGCGTGGCGCGCCGACGGCCGGCTCGACTTTTTCGGCCGCGCCGACGATCAGGTGAAACTGCGCGGCTA
CCGGATCGAGCTCGGCGAAGTGGAGGCGACGCTCGCCCGGCATCCGGACGTCGCCAACGCGGCGGCGAGCGTCGATCTGG
ACGCGAACGGCATCGCGCGGCTCGTCTGCGCGTACGACTGCCGCGCCGGCCGCGGCGTCGAGCCCGCGCCGCTGCGCGCG
TGGCTCGCGACGCAGTTGCCGGACTACATGGTTCCCGGCCGGTGCCGCCGGCTCGACGCGCTGCCGCGCAACGCGAGCGG
CAAGATCGACCGCGCGGCGCTGGCGCGCGGCGTCGACGCGCCGCGTGACGGCGCCGCGCCGCGCGATCCGGTCGAGCTGC
GGCTCGAGCGCGTGTGGGAAGCGGTGCTCGACGTTCAGCCGGTCGGCGTCGATCGGACGTTCTTCGATCTCGGCGGCCAT
TCGCTGCTGGCCGTGCGGCTGATGGCGGAAGTCAAGCGCGAGTTCGGCTGCGATCTGCCGCTCGCGTCGCTGTTCGAGGC
GCCCACCGTCGCCGCGCAGGCGGCGCTCATCCGGCAGCGCGAGCGGGCGCACCCGGTGGTGGTGCGCGTCAATCGCGGCA
TCGACGGCGAGCGCCCGGTGTTCCTCGTGCACCCGACGGGCGGCAACGTGCTTTGCTACCGCGATCTCGCGCGGCGGCTC
GGGCCGGCCCGGCCGATCTACGCGCTGCAGGACCCGGGCCTCGAGGGCGACGCCGGCTACGACAGCGTCGAGGAGCTGGC
GGCGCGCCATATCGCGCACATCCGCCCGCTTGCGGGCGACGGCCCGTATTACCTCGCGGGCTGGTCGTCGGGCGGCGTCG
TCGCGTTCGAGATCGCGCGCCAGTTGCTCGCGCAGCGGTGCGAGGTCGGGCTGCTCGCGTTGATCGACAGCGTCGCGTCC
GACGGCGCGCAGCCGGCCCCGCGCACCGACGCCGAGCTGATCGGCTCGATCGGCCGGCTGCTCGCGTTCGCGGCGGGCGT
CGACGCGCCGGATCTGGCGGCGCTCGAACCGTCGGCCGCGATGGCGCGGCTGCGCGAGCTGGCCGTCGCGGCCGGCTCGC
TGCCGCCCGATGCGCCGCCCGAGCGGATGCGCCGGCTTTTCGACGTCTTCCGCCGCAACGCCGCCGCCGTGCGCCGCTAC
CGGCCCGGGCCGTATCCGCGCCGCGTGCTGCTGCTGCGCGCAACGCAGCCGCTGCCCGAACCGGTGCGCGACGCCGCCGC
GCGCCAGCGCGGCGATTCGCCGGAGCTGGGCTGGGAGCGCGTCGCGGTGGTGAGCCGCTGCGACATCCCCGCGCATCATC
TGTCGATCGTCCACGAGCCGGCCGCGGCGCTCGTCGGCGCGCGGATTCGCGACGCGCTGCACGCGGCGGACCGCATCGAG
GCGATCGGCGAGCGGGTTTTCTTCACGTTGCTCGGACACTGA

Upstream 100 bases:

>100_bases
CGAGCCGGACCTGCTGGGCGCGGCGGAGCGGCGGCTCGTCACGGAGGATTTTCAGGGCCCGCAGGTGAAACCCGCCCGTT
GAACGCCCGGGCATCGGCCG

Downstream 100 bases:

>100_bases
TGGAGGCGAGCCGACCGATGACGACAAGCGCTTCTTCGCCGAACCTTGCTTTCGCCGCCGGCGAGCGGCCCGCCGCGCCG
GCGATCGAAGCGGTGCTGCC

Product: peptide synthase/polyketide synthase

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: Tyrocidine synthase III; ATP-dependent asparagine adenylase; AsnA; Asparagine activase; ATP-dependent glutamine adenylase; GlnA; Glutamine activase; ATP-dependent tyrosine adenylase; TyrA; Tyrosine activase; ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent ornithine adenylase; OrnA; Ornithine activase; ATP-dependent leucine adenylase; LeuA; Leucine activase [H]

Number of amino acids: Translated: 893; Mature: 892

Protein sequence:

>893_residues
MPPAPPRAPDRLPVQEAPPRLTAPARERPVRALPARAAGGGRRGANACRDASAARPGARDGDAPRDAGGRRSPTNTAELP
AARRRYMLEDSGARIVLTLPDAADDLPRDLALVCVYPGEADVDVNIDARTAASGPTARVTADAPADAGADATTGACPDAW
PAPDPTQAAYVLYTSGSTGRPKGVVVTHGSLANHMAWMTRAFPLDAHDAVLQKTSAAFDASIWEFFLPLLAGARLVMAPP
GLERDVPALVATLARERITVLQLVPSLLRVLVDAPGFGACDALRCVFCGGEALTADLARRFAAAHRAALVNLYGPTETTI
QVCAERVDAADDPVPVGRPIDNVRLYVVDSRNRLSPVGVRGEILIGGAAPARGYLDRPALTAARFVADPIDPRAPRVYRS
GDVGAWRADGRLDFFGRADDQVKLRGYRIELGEVEATLARHPDVANAAASVDLDANGIARLVCAYDCRAGRGVEPAPLRA
WLATQLPDYMVPGRCRRLDALPRNASGKIDRAALARGVDAPRDGAAPRDPVELRLERVWEAVLDVQPVGVDRTFFDLGGH
SLLAVRLMAEVKREFGCDLPLASLFEAPTVAAQAALIRQRERAHPVVVRVNRGIDGERPVFLVHPTGGNVLCYRDLARRL
GPARPIYALQDPGLEGDAGYDSVEELAARHIAHIRPLAGDGPYYLAGWSSGGVVAFEIARQLLAQRCEVGLLALIDSVAS
DGAQPAPRTDAELIGSIGRLLAFAAGVDAPDLAALEPSAAMARLRELAVAAGSLPPDAPPERMRRLFDVFRRNAAAVRRY
RPGPYPRRVLLLRATQPLPEPVRDAAARQRGDSPELGWERVAVVSRCDIPAHHLSIVHEPAAALVGARIRDALHAADRIE
AIGERVFFTLLGH

Sequences:

>Translated_893_residues
MPPAPPRAPDRLPVQEAPPRLTAPARERPVRALPARAAGGGRRGANACRDASAARPGARDGDAPRDAGGRRSPTNTAELP
AARRRYMLEDSGARIVLTLPDAADDLPRDLALVCVYPGEADVDVNIDARTAASGPTARVTADAPADAGADATTGACPDAW
PAPDPTQAAYVLYTSGSTGRPKGVVVTHGSLANHMAWMTRAFPLDAHDAVLQKTSAAFDASIWEFFLPLLAGARLVMAPP
GLERDVPALVATLARERITVLQLVPSLLRVLVDAPGFGACDALRCVFCGGEALTADLARRFAAAHRAALVNLYGPTETTI
QVCAERVDAADDPVPVGRPIDNVRLYVVDSRNRLSPVGVRGEILIGGAAPARGYLDRPALTAARFVADPIDPRAPRVYRS
GDVGAWRADGRLDFFGRADDQVKLRGYRIELGEVEATLARHPDVANAAASVDLDANGIARLVCAYDCRAGRGVEPAPLRA
WLATQLPDYMVPGRCRRLDALPRNASGKIDRAALARGVDAPRDGAAPRDPVELRLERVWEAVLDVQPVGVDRTFFDLGGH
SLLAVRLMAEVKREFGCDLPLASLFEAPTVAAQAALIRQRERAHPVVVRVNRGIDGERPVFLVHPTGGNVLCYRDLARRL
GPARPIYALQDPGLEGDAGYDSVEELAARHIAHIRPLAGDGPYYLAGWSSGGVVAFEIARQLLAQRCEVGLLALIDSVAS
DGAQPAPRTDAELIGSIGRLLAFAAGVDAPDLAALEPSAAMARLRELAVAAGSLPPDAPPERMRRLFDVFRRNAAAVRRY
RPGPYPRRVLLLRATQPLPEPVRDAAARQRGDSPELGWERVAVVSRCDIPAHHLSIVHEPAAALVGARIRDALHAADRIE
AIGERVFFTLLGH
>Mature_892_residues
PPAPPRAPDRLPVQEAPPRLTAPARERPVRALPARAAGGGRRGANACRDASAARPGARDGDAPRDAGGRRSPTNTAELPA
ARRRYMLEDSGARIVLTLPDAADDLPRDLALVCVYPGEADVDVNIDARTAASGPTARVTADAPADAGADATTGACPDAWP
APDPTQAAYVLYTSGSTGRPKGVVVTHGSLANHMAWMTRAFPLDAHDAVLQKTSAAFDASIWEFFLPLLAGARLVMAPPG
LERDVPALVATLARERITVLQLVPSLLRVLVDAPGFGACDALRCVFCGGEALTADLARRFAAAHRAALVNLYGPTETTIQ
VCAERVDAADDPVPVGRPIDNVRLYVVDSRNRLSPVGVRGEILIGGAAPARGYLDRPALTAARFVADPIDPRAPRVYRSG
DVGAWRADGRLDFFGRADDQVKLRGYRIELGEVEATLARHPDVANAAASVDLDANGIARLVCAYDCRAGRGVEPAPLRAW
LATQLPDYMVPGRCRRLDALPRNASGKIDRAALARGVDAPRDGAAPRDPVELRLERVWEAVLDVQPVGVDRTFFDLGGHS
LLAVRLMAEVKREFGCDLPLASLFEAPTVAAQAALIRQRERAHPVVVRVNRGIDGERPVFLVHPTGGNVLCYRDLARRLG
PARPIYALQDPGLEGDAGYDSVEELAARHIAHIRPLAGDGPYYLAGWSSGGVVAFEIARQLLAQRCEVGLLALIDSVASD
GAQPAPRTDAELIGSIGRLLAFAAGVDAPDLAALEPSAAMARLRELAVAAGSLPPDAPPERMRRLFDVFRRNAAAVRRYR
PGPYPRRVLLLRATQPLPEPVRDAAARQRGDSPELGWERVAVVSRCDIPAHHLSIVHEPAAALVGARIRDALHAADRIEA
IGERVFFTLLGH

Specific function: Incorporates six amino acids (for tyrocidine A, Asn, Gln, Tyr, Val, Orn, and Leu) in their L-configuration into the peptide product [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 6 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=438, Percent_Identity=26.027397260274, Blast_Score=121, Evalue=4e-27,
Organism=Homo sapiens, GI187761345, Length=404, Percent_Identity=26.2376237623762, Blast_Score=111, Evalue=3e-24,
Organism=Homo sapiens, GI187761343, Length=404, Percent_Identity=26.2376237623762, Blast_Score=111, Evalue=3e-24,
Organism=Homo sapiens, GI42544132, Length=364, Percent_Identity=27.1978021978022, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI38505220, Length=364, Percent_Identity=27.7472527472527, Blast_Score=94, Evalue=8e-19,
Organism=Homo sapiens, GI122937307, Length=366, Percent_Identity=27.8688524590164, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI41872631, Length=238, Percent_Identity=31.0924369747899, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI115511026, Length=368, Percent_Identity=24.7282608695652, Blast_Score=77, Evalue=1e-13,
Organism=Homo sapiens, GI157311624, Length=381, Percent_Identity=25.7217847769029, Blast_Score=77, Evalue=1e-13,
Organism=Homo sapiens, GI157311622, Length=381, Percent_Identity=25.7217847769029, Blast_Score=77, Evalue=1e-13,
Organism=Homo sapiens, GI58082049, Length=389, Percent_Identity=25.9640102827763, Blast_Score=76, Evalue=2e-13,
Organism=Escherichia coli, GI1786801, Length=704, Percent_Identity=34.8011363636364, Blast_Score=326, Evalue=5e-90,
Organism=Escherichia coli, GI1788107, Length=367, Percent_Identity=26.158038147139, Blast_Score=94, Evalue=4e-20,
Organism=Escherichia coli, GI145693145, Length=367, Percent_Identity=28.6103542234332, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1790505, Length=368, Percent_Identity=25.5434782608696, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1786810, Length=382, Percent_Identity=26.7015706806283, Blast_Score=83, Evalue=8e-17,
Organism=Escherichia coli, GI221142682, Length=356, Percent_Identity=25.561797752809, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1789201, Length=366, Percent_Identity=27.0491803278689, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17556356, Length=429, Percent_Identity=27.039627039627, Blast_Score=121, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17550940, Length=568, Percent_Identity=22.3591549295775, Blast_Score=106, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI32564422, Length=403, Percent_Identity=26.302729528536, Blast_Score=102, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI32564420, Length=403, Percent_Identity=26.302729528536, Blast_Score=102, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI71994694, Length=370, Percent_Identity=24.0540540540541, Blast_Score=100, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71994703, Length=368, Percent_Identity=23.9130434782609, Blast_Score=100, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71994690, Length=369, Percent_Identity=24.1192411924119, Blast_Score=99, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17538037, Length=366, Percent_Identity=22.4043715846995, Blast_Score=83, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17559526, Length=363, Percent_Identity=23.6914600550964, Blast_Score=79, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319591, Length=530, Percent_Identity=30.377358490566, Blast_Score=198, Evalue=4e-51,
Organism=Saccharomyces cerevisiae, GI6319699, Length=357, Percent_Identity=22.6890756302521, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24648676, Length=464, Percent_Identity=31.4655172413793, Blast_Score=178, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24582852, Length=463, Percent_Identity=24.1900647948164, Blast_Score=106, Evalue=9e-23,
Organism=Drosophila melanogaster, GI24581924, Length=367, Percent_Identity=25.8855585831063, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24648257, Length=247, Percent_Identity=28.7449392712551, Blast_Score=78, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 95239; Mature: 95107

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPAPPRAPDRLPVQEAPPRLTAPARERPVRALPARAAGGGRRGANACRDASAARPGARD
CCCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHCCCCCCCCCCCCCHHHHHHHCCCCCCCC
GDAPRDAGGRRSPTNTAELPAARRRYMLEDSGARIVLTLPDAADDLPRDLALVCVYPGEA
CCCCCCCCCCCCCCCCHHCCHHHHHHEEECCCCEEEEECCCCCCCCCCCEEEEEEECCCC
DVDVNIDARTAASGPTARVTADAPADAGADATTGACPDAWPAPDPTQAAYVLYTSGSTGR
CEEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCC
PKGVVVTHGSLANHMAWMTRAFPLDAHDAVLQKTSAAFDASIWEFFLPLLAGARLVMAPP
CCEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCC
GLERDVPALVATLARERITVLQLVPSLLRVLVDAPGFGACDALRCVFCGGEALTADLARR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHEEEECCHHHHHHHHHH
FAAAHRAALVNLYGPTETTIQVCAERVDAADDPVPVGRPIDNVRLYVVDSRNRLSPVGVR
HHHHHHHEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCC
GEILIGGAAPARGYLDRPALTAARFVADPIDPRAPRVYRSGDVGAWRADGRLDFFGRADD
EEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEECCCCCCEECCCCEEECCCCCC
QVKLRGYRIELGEVEATLARHPDVANAAASVDLDANGIARLVCAYDCRAGRGVEPAPLRA
EEEEEEEEEEECHHHHHHHCCCCHHHHHEEECCCCCCHHHHHHHHHCCCCCCCCCHHHHH
WLATQLPDYMVPGRCRRLDALPRNASGKIDRAALARGVDAPRDGAAPRDPVELRLERVWE
HHHHCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
AVLDVQPVGVDRTFFDLGGHSLLAVRLMAEVKREFGCDLPLASLFEAPTVAAQAALIRQR
HHHCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHH
ERAHPVVVRVNRGIDGERPVFLVHPTGGNVLCYRDLARRLGPARPIYALQDPGLEGDAGY
HCCCCEEEEEECCCCCCCCEEEEECCCCCEEEHHHHHHHCCCCCCEEEECCCCCCCCCCC
DSVEELAARHIAHIRPLAGDGPYYLAGWSSGGVVAFEIARQLLAQRCEVGLLALIDSVAS
HHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEHHHHHHHHHHHHHCHHHHHHHHHHHH
DGAQPAPRTDAELIGSIGRLLAFAAGVDAPDLAALEPSAAMARLRELAVAAGSLPPDAPP
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCH
ERMRRLFDVFRRNAAAVRRYRPGPYPRRVLLLRATQPLPEPVRDAAARQRGDSPELGWER
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCHHH
VAVVSRCDIPAHHLSIVHEPAAALVGARIRDALHAADRIEAIGERVFFTLLGH
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PPAPPRAPDRLPVQEAPPRLTAPARERPVRALPARAAGGGRRGANACRDASAARPGARD
CCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHCCCCCCCCCCCCCHHHHHHHCCCCCCCC
GDAPRDAGGRRSPTNTAELPAARRRYMLEDSGARIVLTLPDAADDLPRDLALVCVYPGEA
CCCCCCCCCCCCCCCCHHCCHHHHHHEEECCCCEEEEECCCCCCCCCCCEEEEEEECCCC
DVDVNIDARTAASGPTARVTADAPADAGADATTGACPDAWPAPDPTQAAYVLYTSGSTGR
CEEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCC
PKGVVVTHGSLANHMAWMTRAFPLDAHDAVLQKTSAAFDASIWEFFLPLLAGARLVMAPP
CCEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCC
GLERDVPALVATLARERITVLQLVPSLLRVLVDAPGFGACDALRCVFCGGEALTADLARR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHEEEECCHHHHHHHHHH
FAAAHRAALVNLYGPTETTIQVCAERVDAADDPVPVGRPIDNVRLYVVDSRNRLSPVGVR
HHHHHHHEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCC
GEILIGGAAPARGYLDRPALTAARFVADPIDPRAPRVYRSGDVGAWRADGRLDFFGRADD
EEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEECCCCCCEECCCCEEECCCCCC
QVKLRGYRIELGEVEATLARHPDVANAAASVDLDANGIARLVCAYDCRAGRGVEPAPLRA
EEEEEEEEEEECHHHHHHHCCCCHHHHHEEECCCCCCHHHHHHHHHCCCCCCCCCHHHHH
WLATQLPDYMVPGRCRRLDALPRNASGKIDRAALARGVDAPRDGAAPRDPVELRLERVWE
HHHHCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
AVLDVQPVGVDRTFFDLGGHSLLAVRLMAEVKREFGCDLPLASLFEAPTVAAQAALIRQR
HHHCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHH
ERAHPVVVRVNRGIDGERPVFLVHPTGGNVLCYRDLARRLGPARPIYALQDPGLEGDAGY
HCCCCEEEEEECCCCCCCCEEEEECCCCCEEEHHHHHHHCCCCCCEEEECCCCCCCCCCC
DSVEELAARHIAHIRPLAGDGPYYLAGWSSGGVVAFEIARQLLAQRCEVGLLALIDSVAS
HHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEHHHHHHHHHHHHHCHHHHHHHHHHHH
DGAQPAPRTDAELIGSIGRLLAFAAGVDAPDLAALEPSAAMARLRELAVAAGSLPPDAPP
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCH
ERMRRLFDVFRRNAAAVRRYRPGPYPRRVLLLRATQPLPEPVRDAAARQRGDSPELGWER
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCHHH
VAVVSRCDIPAHHLSIVHEPAAALVGARIRDALHAADRIEAIGERVFFTLLGH
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9352938; 10801488 [H]