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The map label for this gene is grsT [H]

Identifier: 53722195

GI number: 53722195

Start: 1558802

End: 1559686

Strand: Reverse

Name: grsT [H]

Synonym: BPSS1167

Alternate gene names: 53722195

Gene position: 1559686-1558802 (Counterclockwise)

Preceding gene: 53722196

Following gene: 53722194

Centisome position: 49.15

GC content: 72.77

Gene sequence:

>885_bases
ATGACCAGCATCCCCGTTAGACTCGATCGGTTCGCGCCGGCGGCCGCGCCGGCCGACCGGGCCGACCGGGCCGATTCGGC
CGCCGCCACGGACGGCGCCCCGGCGGCGGCGTTTCCCGCCACGGCCGCGAAGGCCGCGATCCGCACGCTGGTTGCGCCGT
CGCCCGGCGGCGCGCACGTGCTGTGCATCCCATGGGCGGGCGCGAGCATCGAGCGCTTCTTCGCGTGGAAGCGGCACCTG
CCGGCGGGCGTCGGCTTGTCGGGCGTCCAGTTGCCGGGGCGCGGCGCGCGTGCGCACGAGCCGTCGCCGACGGATCTCGT
CGCGCTGCTCGACGAGATCGCGGCCGAGTACCTGGCGCTGCGCGACCCGCCGCGCATCCTGTTCGGGCACAGCTTCGGCG
CGCTGATCGCGTTCGAGATCGCGACGCGCGTGAGCCGGGCGGCCGGCCAGGCGGGCGGCGATCCGTTCGTGCGGCTCGTC
GTGTCGGGGCTGTCCGCGCCGAGCGTGATCGCCGAGGAAGAGCGCATCGCCCATCTCGACGACGACGCGTTCAGCGCGCA
AGTGCACGCGCTCAACGGCATGCCGCCCGAAATCGCGCGCAGCCCCGAATCGCTGCGCTATTTCATGACTGTCCTGCGGT
GCGATTTCCGGCTGTACGAATCCTATGCGTTCGACGCGAATCGCCCGCCGCTGCGCTGCCCGATCGCCGTGTGCTCCGGC
CGCGACGATCCGAGCGTGTCGGAGCACGGGCTGAACGCGTGGGCGGCGCTCACGACGGGCGAGTGCCGGCGTCACGATTT
CGACGGCGATCATTTCTTCATCGCGGACCACGCGGCCGCGATGCTGGGCCTCGCGCTGGACGCCGAAAGCACGCTCGCCG
GCTGA

Upstream 100 bases:

>100_bases
GCGTCGCCGGACGGTCTGAACGTCTATCGGCGTCTCGGCTTTCGGCCGGTGTGCGAGTTTCGCGTGTATTCGAACCGCGC
CGCGGTTCTGGAGAGAAGTC

Downstream 100 bases:

>100_bases
GCGGCGCCGCCTTCCCTTCCTTTTTTCGAATCGTCATTTCCTGTCGACCACGTTCATGAGCGAGACCTCGAAGCGCCATC
CTTCCCTCGTGTTGATCCTG

Product: thioesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MTSIPVRLDRFAPAAAPADRADRADSAAATDGAPAAAFPATAAKAAIRTLVAPSPGGAHVLCIPWAGASIERFFAWKRHL
PAGVGLSGVQLPGRGARAHEPSPTDLVALLDEIAAEYLALRDPPRILFGHSFGALIAFEIATRVSRAAGQAGGDPFVRLV
VSGLSAPSVIAEEERIAHLDDDAFSAQVHALNGMPPEIARSPESLRYFMTVLRCDFRLYESYAFDANRPPLRCPIAVCSG
RDDPSVSEHGLNAWAALTTGECRRHDFDGDHFFIADHAAAMLGLALDAESTLAG

Sequences:

>Translated_294_residues
MTSIPVRLDRFAPAAAPADRADRADSAAATDGAPAAAFPATAAKAAIRTLVAPSPGGAHVLCIPWAGASIERFFAWKRHL
PAGVGLSGVQLPGRGARAHEPSPTDLVALLDEIAAEYLALRDPPRILFGHSFGALIAFEIATRVSRAAGQAGGDPFVRLV
VSGLSAPSVIAEEERIAHLDDDAFSAQVHALNGMPPEIARSPESLRYFMTVLRCDFRLYESYAFDANRPPLRCPIAVCSG
RDDPSVSEHGLNAWAALTTGECRRHDFDGDHFFIADHAAAMLGLALDAESTLAG
>Mature_293_residues
TSIPVRLDRFAPAAAPADRADRADSAAATDGAPAAAFPATAAKAAIRTLVAPSPGGAHVLCIPWAGASIERFFAWKRHLP
AGVGLSGVQLPGRGARAHEPSPTDLVALLDEIAAEYLALRDPPRILFGHSFGALIAFEIATRVSRAAGQAGGDPFVRLVV
SGLSAPSVIAEEERIAHLDDDAFSAQVHALNGMPPEIARSPESLRYFMTVLRCDFRLYESYAFDANRPPLRCPIAVCSGR
DDPSVSEHGLNAWAALTTGECRRHDFDGDHFFIADHAAAMLGLALDAESTLAG

Specific function: Probable thioesterase involved in the biosynthesis of gramicidin S [H]

COG id: COG3208

COG function: function code Q; Predicted thioesterase involved in non-ribosomal peptide biosynthesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioesterase family [H]

Homologues:

Organism=Homo sapiens, GI89257335, Length=228, Percent_Identity=24.5614035087719, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI8922871, Length=202, Percent_Identity=24.7524752475248, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012223
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00975 Thioesterase [H]

EC number: NA

Molecular weight: Translated: 31024; Mature: 30893

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSIPVRLDRFAPAAAPADRADRADSAAATDGAPAAAFPATAAKAAIRTLVAPSPGGAHV
CCCCCCCHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEE
LCIPWAGASIERFFAWKRHLPAGVGLSGVQLPGRGARAHEPSPTDLVALLDEIAAEYLAL
EEEECCCCHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
RDPPRILFGHSFGALIAFEIATRVSRAAGQAGGDPFVRLVVSGLSAPSVIAEEERIAHLD
CCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCC
DDAFSAQVHALNGMPPEIARSPESLRYFMTVLRCDFRLYESYAFDANRPPLRCPIAVCSG
CCHHHHEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECC
RDDPSVSEHGLNAWAALTTGECRRHDFDGDHFFIADHAAAMLGLALDAESTLAG
CCCCCHHHCCCCEEEEECCCCHHCCCCCCCEEEEHHHHHHHHHHHCCCHHHCCC
>Mature Secondary Structure 
TSIPVRLDRFAPAAAPADRADRADSAAATDGAPAAAFPATAAKAAIRTLVAPSPGGAHV
CCCCCCHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEE
LCIPWAGASIERFFAWKRHLPAGVGLSGVQLPGRGARAHEPSPTDLVALLDEIAAEYLAL
EEEECCCCHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
RDPPRILFGHSFGALIAFEIATRVSRAAGQAGGDPFVRLVVSGLSAPSVIAEEERIAHLD
CCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCC
DDAFSAQVHALNGMPPEIARSPESLRYFMTVLRCDFRLYESYAFDANRPPLRCPIAVCSG
CCHHHHEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECC
RDDPSVSEHGLNAWAALTTGECRRHDFDGDHFFIADHAAAMLGLALDAESTLAG
CCCCCHHHCCCCEEEEECCCCHHCCCCCCCEEEEHHHHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2477357; 7512553 [H]