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The map label for this gene is 53722131

Identifier: 53722131

GI number: 53722131

Start: 1481559

End: 1482989

Strand: Reverse

Name: 53722131

Synonym: BPSS1103

Alternate gene names: NA

Gene position: 1482989-1481559 (Counterclockwise)

Preceding gene: 53722132

Following gene: 53722129

Centisome position: 46.74

GC content: 70.16

Gene sequence:

>1431_bases
ATGCGTCGCCTCTTGTGCTGCTTCACGATCGTTCTGGGCTTCCTGTTCGCCGCGCCGTCGCACGCGGGCGACGCGGCCGC
CGTTGGGCAACTGACGGTGGCGCTGTATCCGTGGGTGCCGCGCGTCGACCAGTTCAAGCGCGCGATCGAAACCGAATGGA
AGAAGGCGCAGCCGGGCGTCGCGCTGCGGTTCGTGTCCGCGGACGCGTGGGACGGCGGCTACCGGAACGATCCGCCCGCG
AGCGCCGACGTCTACGTGTACGACGCGATCTTCCTCGACTATTTCCGCAGCCAGAACTGGCTCGAGCCGCTCGCGGCGGA
CGAGATCCAGCACATCGACGATTTCCTGCCGTACGCGATCCAGGGCGTGAAGGCGGGCGACCGGTACTACAGCATCCCGC
AGCTCGGCTGCGCGAACGTGCTGTTCTACCGGAAGGACGACGCGGCGCTCGCGGCCGCGACGACGCTCACGCAGGTGCGC
GGCGCGCTCGAGCAATGCACGTTCACGAGCGAGATCCCGCCGGACAGGCGCGGGCTGATGGTCGACATGTCCGGGCGCAC
GACGAACGCCGCGCTCTATCTGGACGCCGCGCACAGCCGCACGGGCGCATACCCGCTGCCGCTGCCGTGGAACGCGAACG
ACCTGAACGGCGAAGCGCTCGGCAGCCTGCGCGCGCTGATGGCGATGTCGAGCTGGCCGAACGCGACAGCCGAGCTGCCG
GGCCAGTACGATCGCTCGGTATGGTTCAGCGACGGCGAAGGGCGCGCGGTGATCGGCTATTCGGAATCGATGTCGGCGAT
GAGCGAGGCGGCGCGGCGCGATCTCGACTTCAAGTTCCTGCCGCTGTCGGACACGCCGCAGCCGCCGCTCTTCTACGCGG
ACGTGATCGGCGTGAACACGACGACCCACGCGCGCGGCACGCGCGCGCTCGCGGTGCAACTCGCGAACGTGATCGCCGCA
TCGTCGACGATGGTGCAAAGCGTCGGGCCGGACGGCAGCGGCGTGCCGCAATATCTGTTCTCCGCGCGGCGCAGCGTGCT
GCACACGCTCGCGCAGCGCTATCCGCTCTATCGGAAGATGGTCGCGCTGCTGGATGCGCGCGAGCCGGTGATGTTCAAGA
TCGATGCGCAGTCGCGCAACTGGCTCGCCTCGATGAGCGGGCCGATCGCGCAGCGCGCGCGCGCCGATTACCCGTGCGGC
TGCGATATCGACACCGCGCTGCCGATCGCCGACTATCGCGGCGCGCAGGCCGTGTGCCCGACCGTCTGCGCGGCGCAGGG
CGGCTGGAACGGCCAGTGGACCAATCAGTCTCCCGCGGCGCCCGCCGGGCAGTCGGCGTGCGGCTGCAACGCGTGCCCGA
CGTCAGCCGCGGCGAAACTGCCGCGCGCGCTCGCCACCCGCGCCGCGCCCGGCGATCGCGCGAAGCCGTGA

Upstream 100 bases:

>100_bases
TATGGAACTGACGCCCGCGCCGCGCGCCGGCATGCGCGCGCATCGACAAACACCAAGACAAGCGCATCGTTTCGCACGCG
TCATTCGACAAGGAACCATC

Downstream 100 bases:

>100_bases
CACGGGCGGCGCCCGGCCTCGCCGCGGGCGGGCCGGGAGCCCGGCCCGCGAGGCCCGCGCCGCGCCCGAATCGCCTCGCG
CGCGGTCGAACGCGGTTGCG

Product: periplasmic thiamine binding protein

Products: NA

Alternate protein names: Thiaminase I; Thiamine pyridinylase [H]

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MRRLLCCFTIVLGFLFAAPSHAGDAAAVGQLTVALYPWVPRVDQFKRAIETEWKKAQPGVALRFVSADAWDGGYRNDPPA
SADVYVYDAIFLDYFRSQNWLEPLAADEIQHIDDFLPYAIQGVKAGDRYYSIPQLGCANVLFYRKDDAALAAATTLTQVR
GALEQCTFTSEIPPDRRGLMVDMSGRTTNAALYLDAAHSRTGAYPLPLPWNANDLNGEALGSLRALMAMSSWPNATAELP
GQYDRSVWFSDGEGRAVIGYSESMSAMSEAARRDLDFKFLPLSDTPQPPLFYADVIGVNTTTHARGTRALAVQLANVIAA
SSTMVQSVGPDGSGVPQYLFSARRSVLHTLAQRYPLYRKMVALLDAREPVMFKIDAQSRNWLASMSGPIAQRARADYPCG
CDIDTALPIADYRGAQAVCPTVCAAQGGWNGQWTNQSPAAPAGQSACGCNACPTSAAAKLPRALATRAAPGDRAKP

Sequences:

>Translated_476_residues
MRRLLCCFTIVLGFLFAAPSHAGDAAAVGQLTVALYPWVPRVDQFKRAIETEWKKAQPGVALRFVSADAWDGGYRNDPPA
SADVYVYDAIFLDYFRSQNWLEPLAADEIQHIDDFLPYAIQGVKAGDRYYSIPQLGCANVLFYRKDDAALAAATTLTQVR
GALEQCTFTSEIPPDRRGLMVDMSGRTTNAALYLDAAHSRTGAYPLPLPWNANDLNGEALGSLRALMAMSSWPNATAELP
GQYDRSVWFSDGEGRAVIGYSESMSAMSEAARRDLDFKFLPLSDTPQPPLFYADVIGVNTTTHARGTRALAVQLANVIAA
SSTMVQSVGPDGSGVPQYLFSARRSVLHTLAQRYPLYRKMVALLDAREPVMFKIDAQSRNWLASMSGPIAQRARADYPCG
CDIDTALPIADYRGAQAVCPTVCAAQGGWNGQWTNQSPAAPAGQSACGCNACPTSAAAKLPRALATRAAPGDRAKP
>Mature_476_residues
MRRLLCCFTIVLGFLFAAPSHAGDAAAVGQLTVALYPWVPRVDQFKRAIETEWKKAQPGVALRFVSADAWDGGYRNDPPA
SADVYVYDAIFLDYFRSQNWLEPLAADEIQHIDDFLPYAIQGVKAGDRYYSIPQLGCANVLFYRKDDAALAAATTLTQVR
GALEQCTFTSEIPPDRRGLMVDMSGRTTNAALYLDAAHSRTGAYPLPLPWNANDLNGEALGSLRALMAMSSWPNATAELP
GQYDRSVWFSDGEGRAVIGYSESMSAMSEAARRDLDFKFLPLSDTPQPPLFYADVIGVNTTTHARGTRALAVQLANVIAA
SSTMVQSVGPDGSGVPQYLFSARRSVLHTLAQRYPLYRKMVALLDAREPVMFKIDAQSRNWLASMSGPIAQRARADYPCG
CDIDTALPIADYRGAQAVCPTVCAAQGGWNGQWTNQSPAAPAGQSACGCNACPTSAAAKLPRALATRAAPGDRAKP

Specific function: Degrades thiamine by replacing its thiazole moiety with a wide range of nucleophiles [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006059 [H]

Pfam domain/function: PF01547 SBP_bac_1 [H]

EC number: =2.5.1.2 [H]

Molecular weight: Translated: 51436; Mature: 51436

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLLCCFTIVLGFLFAAPSHAGDAAAVGQLTVALYPWVPRVDQFKRAIETEWKKAQPGV
CCHHHHHHHHHHHHHHCCCCCCCCHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHCCCCE
ALRFVSADAWDGGYRNDPPASADVYVYDAIFLDYFRSQNWLEPLAADEIQHIDDFLPYAI
EEEEEECCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
QGVKAGDRYYSIPQLGCANVLFYRKDDAALAAATTLTQVRGALEQCTFTSEIPPDRRGLM
HCCCCCCCEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEE
VDMSGRTTNAALYLDAAHSRTGAYPLPLPWNANDLNGEALGSLRALMAMSSWPNATAELP
EEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
GQYDRSVWFSDGEGRAVIGYSESMSAMSEAARRDLDFKFLPLSDTPQPPLFYADVIGVNT
CCCCCCEEEECCCCCEEEECHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEEEEECCC
TTHARGTRALAVQLANVIAASSTMVQSVGPDGSGVPQYLFSARRSVLHTLAQRYPLYRKM
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHH
VALLDAREPVMFKIDAQSRNWLASMSGPIAQRARADYPCGCDIDTALPIADYRGAQAVCP
HHHHCCCCCEEEEEECCCCCHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHH
TVCAAQGGWNGQWTNQSPAAPAGQSACGCNACPTSAAAKLPRALATRAAPGDRAKP
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRRLLCCFTIVLGFLFAAPSHAGDAAAVGQLTVALYPWVPRVDQFKRAIETEWKKAQPGV
CCHHHHHHHHHHHHHHCCCCCCCCHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHCCCCE
ALRFVSADAWDGGYRNDPPASADVYVYDAIFLDYFRSQNWLEPLAADEIQHIDDFLPYAI
EEEEEECCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
QGVKAGDRYYSIPQLGCANVLFYRKDDAALAAATTLTQVRGALEQCTFTSEIPPDRRGLM
HCCCCCCCEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEE
VDMSGRTTNAALYLDAAHSRTGAYPLPLPWNANDLNGEALGSLRALMAMSSWPNATAELP
EEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
GQYDRSVWFSDGEGRAVIGYSESMSAMSEAARRDLDFKFLPLSDTPQPPLFYADVIGVNT
CCCCCCEEEECCCCCEEEECHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEEEEECCC
TTHARGTRALAVQLANVIAASSTMVQSVGPDGSGVPQYLFSARRSVLHTLAQRYPLYRKM
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHH
VALLDAREPVMFKIDAQSRNWLASMSGPIAQRARADYPCGCDIDTALPIADYRGAQAVCP
HHHHCCCCCEEEEEECCCCCHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHH
TVCAAQGGWNGQWTNQSPAAPAGQSACGCNACPTSAAAKLPRALATRAAPGDRAKP
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8631946; 9843405 [H]