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The map label for this gene is ccrM [H]

Identifier: 53722104

GI number: 53722104

Start: 1448290

End: 1449165

Strand: Reverse

Name: ccrM [H]

Synonym: BPSS1077

Alternate gene names: 53722104

Gene position: 1449165-1448290 (Counterclockwise)

Preceding gene: 53722118

Following gene: 53722089

Centisome position: 45.67

GC content: 66.55

Gene sequence:

>876_bases
GTGATCCGCGCAATGAAACGTGCGTCGACAATGGCCGCTCGACACACGCAACAGTGCGGGCGGCTCGTGCCGCGCGCGCA
TTTCCACTCTCGCAACACGATGACGATTCACGCTACCGACGCCGCGCCCGCGGCCGATCTTTCCCCGCTACTCGACCGAC
TTCACGCAATGGATGCGCTCACGCTCGCGCGCATGCTGCCCGACGCGTCAATCGACATGGTGTTCACCGATCCGCCGTAT
TCGTCGGGCGGACTGCACACGTCGGCGCGCTCGCGGCCGCCGAGCGAGAAGTACATCAACAGCGACACGAAGACTGTCTA
TACCGACTTCGAGAGCGACAACATGGACCAGCGCGCGTGGGCGTTCTGGTGTCACGCCTGGCTGAGCGAATGCCGCCGCG
CGTTGAAGCCGGGCGGGCTGCTCGTGAGCTTCATCGACTGGCGCCAGCTCCCGACGCTGACCGATGTCGTGCAGGCGGCC
GGTTTGATCCTGCGCGGCGTCGCGGTATGGGACAAGACGCCCGGCCGCACGCGGCCGCGGCGCGGCGGCTTCGCGCAGCA
GGCGGAATTCGTCGTATGGGCGAGCCGCGGCGCGATGCGCGACTGCGAGGTGTATCTGCCGGGCGTGTTCCCGTGCCGCT
TGCCGTTGCCGAAGCAACACGTGACCGAGAAGCCGCTCGACATAGCGCGCGAGGTCGTGCGGCTCGTGCCGGCCGGCGGC
GTCGTGTGCGATCTGTTTGCCGGTTCCGGCACGTTTCTCGTCGCGGCGCGCGAGGCCGGCCTACATTGGATCGGGTGTGA
GACGAATGCGGCGTATCACGCGATCGCATTGCATCGCTTGGGTATGTCGAGCGACTCAGCGCTTCAGGTCACTTAA

Upstream 100 bases:

>100_bases
TGTCGTTGAATTTCGTTCGCATCCATACCGGCAATGGTGCCGGTCGCCCGCGCGTGGCGCGAGCACTCGCCTTTGTCGTG
CCGCCGGGTACAGCGCACTC

Downstream 100 bases:

>100_bases
CGACCCATGTCGCTTGCGCTCGATCGCCGCGCGCATGCTTCAACTCGGAGACAGGCGGGCCGACAACCATGTCCGAGCGT
GAGTGTCTTCGACAGCCAGT

Product: site-specific DNA methyltransferase

Products: NA

Alternate protein names: M.BabI; Adenine-specific methyltransferase BabI; DNA methyltransferase CcrM; M.CcrMI ortholog [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MIRAMKRASTMAARHTQQCGRLVPRAHFHSRNTMTIHATDAAPAADLSPLLDRLHAMDALTLARMLPDASIDMVFTDPPY
SSGGLHTSARSRPPSEKYINSDTKTVYTDFESDNMDQRAWAFWCHAWLSECRRALKPGGLLVSFIDWRQLPTLTDVVQAA
GLILRGVAVWDKTPGRTRPRRGGFAQQAEFVVWASRGAMRDCEVYLPGVFPCRLPLPKQHVTEKPLDIAREVVRLVPAGG
VVCDLFAGSGTFLVAAREAGLHWIGCETNAAYHAIALHRLGMSSDSALQVT

Sequences:

>Translated_291_residues
MIRAMKRASTMAARHTQQCGRLVPRAHFHSRNTMTIHATDAAPAADLSPLLDRLHAMDALTLARMLPDASIDMVFTDPPY
SSGGLHTSARSRPPSEKYINSDTKTVYTDFESDNMDQRAWAFWCHAWLSECRRALKPGGLLVSFIDWRQLPTLTDVVQAA
GLILRGVAVWDKTPGRTRPRRGGFAQQAEFVVWASRGAMRDCEVYLPGVFPCRLPLPKQHVTEKPLDIAREVVRLVPAGG
VVCDLFAGSGTFLVAAREAGLHWIGCETNAAYHAIALHRLGMSSDSALQVT
>Mature_291_residues
MIRAMKRASTMAARHTQQCGRLVPRAHFHSRNTMTIHATDAAPAADLSPLLDRLHAMDALTLARMLPDASIDMVFTDPPY
SSGGLHTSARSRPPSEKYINSDTKTVYTDFESDNMDQRAWAFWCHAWLSECRRALKPGGLLVSFIDWRQLPTLTDVVQAA
GLILRGVAVWDKTPGRTRPRRGGFAQQAEFVVWASRGAMRDCEVYLPGVFPCRLPLPKQHVTEKPLDIAREVVRLVPAGG
VVCDLFAGSGTFLVAAREAGLHWIGCETNAAYHAIALHRLGMSSDSALQVT

Specific function: This methylase recognizes the double-stranded sequence GANTC and causes specific methylation on A-2 on both strands. CcrM-mediated methylation has important cellular functions. Appears to contribute to the accurate cell-cycle control of DNA replication an

COG id: COG0863

COG function: function code L; DNA modification methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002941
- InterPro:   IPR002052
- InterPro:   IPR001091 [H]

Pfam domain/function: PF01555 N6_N4_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 32073; Mature: 32073

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRAMKRASTMAARHTQQCGRLVPRAHFHSRNTMTIHATDAAPAADLSPLLDRLHAMDAL
CCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHH
TLARMLPDASIDMVFTDPPYSSGGLHTSARSRPPSEKYINSDTKTVYTDFESDNMDQRAW
HHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHCCCCCCEEEEECCCCCCCHHHH
AFWCHAWLSECRRALKPGGLLVSFIDWRQLPTLTDVVQAAGLILRGVAVWDKTPGRTRPR
HHHHHHHHHHHHHHHCCCCEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
RGGFAQQAEFVVWASRGAMRDCEVYLPGVFPCRLPLPKQHVTEKPLDIAREVVRLVPAGG
CCCCCHHCCEEEEECCCCCCCCEEECCCCCEECCCCCHHHHCCCCHHHHHHHHHHCCCCC
VVCDLFAGSGTFLVAAREAGLHWIGCETNAAYHAIALHRLGMSSDSALQVT
EEEEEECCCCEEEEEEECCCEEEEECCCCCHHHHHHHHHHCCCCCCCEEEC
>Mature Secondary Structure
MIRAMKRASTMAARHTQQCGRLVPRAHFHSRNTMTIHATDAAPAADLSPLLDRLHAMDAL
CCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHH
TLARMLPDASIDMVFTDPPYSSGGLHTSARSRPPSEKYINSDTKTVYTDFESDNMDQRAW
HHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHCCCCCCEEEEECCCCCCCHHHH
AFWCHAWLSECRRALKPGGLLVSFIDWRQLPTLTDVVQAAGLILRGVAVWDKTPGRTRPR
HHHHHHHHHHHHHHHCCCCEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
RGGFAQQAEFVVWASRGAMRDCEVYLPGVFPCRLPLPKQHVTEKPLDIAREVVRLVPAGG
CCCCCHHCCEEEEECCCCCCCCEEECCCCCEECCCCCHHHHCCCCHHHHHHHHHHCCCCC
VVCDLFAGSGTFLVAAREAGLHWIGCETNAAYHAIALHRLGMSSDSALQVT
EEEEEECCCCEEEEEEECCCEEEEECCCCCHHHHHHHHHHCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]