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The map label for this gene is czcC

Identifier: 53722064

GI number: 53722064

Start: 1421864

End: 1423222

Strand: Reverse

Name: czcC

Synonym: BPSS1043

Alternate gene names: 53722064

Gene position: 1423222-1421864 (Counterclockwise)

Preceding gene: 53722065

Following gene: 53722063

Centisome position: 44.85

GC content: 74.61

Gene sequence:

>1359_bases
GTGTCGGCCGCGATCGCGGCGTCGGCGGTGCAGGCGCAAGCGCAGCCCGCGCCGGCCCCGTCCGCGCCCGACGGCCCGGC
CGCCACACCGCCGGACGCCCGCGCGGCCTCCGTCTCCGTCACGCCCGCCGTCTCTCCCGCACCGATTTCGACTTCGACTG
TGTCCGTCGCGCCGCCCGCGCTGTCGCTCGACGACGCACTGGCCCTAGCCGCAGCGAACAACCCGCTGCTGAAAAGCGCG
CGATCGAGCGCCGACGCATCCGTCGGCGCGCTCGTCCAGGCGGGCGCGCGTCCGAATCCGACCGTGTCGTTCCTGCAGGA
AGGGTTCGGGCGGCAGGAGCGCACGACGACCGCCGTCGTCAGCCAGCCGATCGAGCTCGGCGGCAAGCGGCGCTCGCGCG
TCGACGCCGCATCGTACGGCCGCGAATCCGCGCTCGCGTCGCTCGACGGCCGCGCGGCCGCGCTGCGCGCCGACGTGACG
GGCGCGTTCTACGGCGTGCTCGCCGCGCAGCGCCAGTTGCAGGTCGCCGACGAATCGGCCGCGATCGCCGCGCGCTCGGC
CGACATGGCCGACAAGCGCGCCCGCGCGGGCAAGGTGTCGCCCGTCGAGGCGACGAAGGCGCGCGTCGCGCAGACGGCCG
CGCAGATCGAGCTGTCGAACGCGCAAACGCGGGTGGCGGCGGCGCTCGCGCGGCTCGCGAACGCGACAGGCAGCGCCGAC
GTGCGCGGGCGCGCCGCGTCGGGCGACCTCGACGCGTTGCCCGCCGCCGAGCCGCTGCCGCAACTGCTCGGCCGGCTCGA
CGACGCGCCGCTCGCGCGCGCGGCGAAAGCCGACATGCTGCGCACGAACGCGCAGATCGCGATCGAGCGCGCGAAGCGCG
TGCCGGACATCACGGTGAGCGCGGGCGTCAAGCATGTCGTCACGGGCGGCGCGCCGGACAACCAGGCGGTCGTCGGCATC
TCGATTCCGCTGCCGCTCTTCGACACGAACAGGGGCGCGCTGCTCGAAGCCGTCCACAACGCGGCGAAGGCAAGCGCCGA
TTTCGACGCCGAGCGCGCGCGGCTGCGGCTCGATCTCACCCAGGCCTATGCGAACTACGAGCGCGCGACGGGCGAGGCGC
GGCGGCTGAAGGCCGACGTGCTGCCCGCCGCGCGGCAGTCGCTCGACGCGATGTCGCGCGGCTACCAGCTCGGCAAGTTC
GGCTTTCTCGACGTGCTCGACGCGCAGCGCACGCTGTTCGATGCGCAATCGCGCTACGTGCAGGCGCTCGCCGACGCGCA
TCAGTCGTATGCGGACATCGAGCGCGTCGTCGGCGCGCCGGCGCGCGACGCTTCCCGCCCCCTCGCCCAACTTCGCTGA

Upstream 100 bases:

>100_bases
GTCATGTTCGCCTCATGTTTGCATTGCGGCACGTCCGTAGCATCGATCGCGTTTCACCGGAACTCGATCACTCATGCCCA
AGCGTATCTTCGCCGCACTC

Downstream 100 bases:

>100_bases
AGAACTCGCCATGCAACGCAAGCCCCTGATTCTCGCCGGCGCGGCCGCGGCCGGCGCTCTCGCCATCGTGCTGGCGCTCG
CGCGCGCGCCGTCCACGTCG

Product: cobalt-zinc-cadmium resistance protein

Products: NA

Alternate protein names: Cation efflux system protein CzcC [H]

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MSAAIAASAVQAQAQPAPAPSAPDGPAATPPDARAASVSVTPAVSPAPISTSTVSVAPPALSLDDALALAAANNPLLKSA
RSSADASVGALVQAGARPNPTVSFLQEGFGRQERTTTAVVSQPIELGGKRRSRVDAASYGRESALASLDGRAAALRADVT
GAFYGVLAAQRQLQVADESAAIAARSADMADKRARAGKVSPVEATKARVAQTAAQIELSNAQTRVAAALARLANATGSAD
VRGRAASGDLDALPAAEPLPQLLGRLDDAPLARAAKADMLRTNAQIAIERAKRVPDITVSAGVKHVVTGGAPDNQAVVGI
SIPLPLFDTNRGALLEAVHNAAKASADFDAERARLRLDLTQAYANYERATGEARRLKADVLPAARQSLDAMSRGYQLGKF
GFLDVLDAQRTLFDAQSRYVQALADAHQSYADIERVVGAPARDASRPLAQLR

Sequences:

>Translated_452_residues
MSAAIAASAVQAQAQPAPAPSAPDGPAATPPDARAASVSVTPAVSPAPISTSTVSVAPPALSLDDALALAAANNPLLKSA
RSSADASVGALVQAGARPNPTVSFLQEGFGRQERTTTAVVSQPIELGGKRRSRVDAASYGRESALASLDGRAAALRADVT
GAFYGVLAAQRQLQVADESAAIAARSADMADKRARAGKVSPVEATKARVAQTAAQIELSNAQTRVAAALARLANATGSAD
VRGRAASGDLDALPAAEPLPQLLGRLDDAPLARAAKADMLRTNAQIAIERAKRVPDITVSAGVKHVVTGGAPDNQAVVGI
SIPLPLFDTNRGALLEAVHNAAKASADFDAERARLRLDLTQAYANYERATGEARRLKADVLPAARQSLDAMSRGYQLGKF
GFLDVLDAQRTLFDAQSRYVQALADAHQSYADIERVVGAPARDASRPLAQLR
>Mature_451_residues
SAAIAASAVQAQAQPAPAPSAPDGPAATPPDARAASVSVTPAVSPAPISTSTVSVAPPALSLDDALALAAANNPLLKSAR
SSADASVGALVQAGARPNPTVSFLQEGFGRQERTTTAVVSQPIELGGKRRSRVDAASYGRESALASLDGRAAALRADVTG
AFYGVLAAQRQLQVADESAAIAARSADMADKRARAGKVSPVEATKARVAQTAAQIELSNAQTRVAAALARLANATGSADV
RGRAASGDLDALPAAEPLPQLLGRLDDAPLARAAKADMLRTNAQIAIERAKRVPDITVSAGVKHVVTGGAPDNQAVVGIS
IPLPLFDTNRGALLEAVHNAAKASADFDAERARLRLDLTQAYANYERATGEARRLKADVLPAARQSLDAMSRGYQLGKFG
FLDVLDAQRTLFDAQSRYVQALADAHQSYADIERVVGAPARDASRPLAQLR

Specific function: CzcC protein appears to modify the specificity of the system, perhaps by acting on the CzcB protein. When the CzcC protein is added to CzcA and CzcB, the efflux system gains specificity for cadmium and cobalt [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 46512; Mature: 46380

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAAIAASAVQAQAQPAPAPSAPDGPAATPPDARAASVSVTPAVSPAPISTSTVSVAPPA
CCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCEEEECCCC
LSLDDALALAAANNPLLKSARSSADASVGALVQAGARPNPTVSFLQEGFGRQERTTTAVV
CCHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHH
SQPIELGGKRRSRVDAASYGRESALASLDGRAAALRADVTGAFYGVLAAQRQLQVADESA
HCHHHHCCCHHHHCCHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
AIAARSADMADKRARAGKVSPVEATKARVAQTAAQIELSNAQTRVAAALARLANATGSAD
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHCCCCCCC
VRGRAASGDLDALPAAEPLPQLLGRLDDAPLARAAKADMLRTNAQIAIERAKRVPDITVS
CCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCEEHH
AGVKHVVTGGAPDNQAVVGISIPLPLFDTNRGALLEAVHNAAKASADFDAERARLRLDLT
CCCCEEEECCCCCCCEEEEEEECCCEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
QAYANYERATGEARRLKADVLPAARQSLDAMSRGYQLGKFGFLDVLDAQRTLFDAQSRYV
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
QALADAHQSYADIERVVGAPARDASRPLAQLR
HHHHHHHHHHHHHHHHHCCCCCHHCCCHHHCC
>Mature Secondary Structure 
SAAIAASAVQAQAQPAPAPSAPDGPAATPPDARAASVSVTPAVSPAPISTSTVSVAPPA
CCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCEEEECCCC
LSLDDALALAAANNPLLKSARSSADASVGALVQAGARPNPTVSFLQEGFGRQERTTTAVV
CCHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHH
SQPIELGGKRRSRVDAASYGRESALASLDGRAAALRADVTGAFYGVLAAQRQLQVADESA
HCHHHHCCCHHHHCCHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
AIAARSADMADKRARAGKVSPVEATKARVAQTAAQIELSNAQTRVAAALARLANATGSAD
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHCCCCCCC
VRGRAASGDLDALPAAEPLPQLLGRLDDAPLARAAKADMLRTNAQIAIERAKRVPDITVS
CCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCEEHH
AGVKHVVTGGAPDNQAVVGISIPLPLFDTNRGALLEAVHNAAKASADFDAERARLRLDLT
CCCCEEEECCCCCCCEEEEEEECCCEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
QAYANYERATGEARRLKADVLPAARQSLDAMSRGYQLGKFGFLDVLDAQRTLFDAQSRYV
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
QALADAHQSYADIERVVGAPARDASRPLAQLR
HHHHHHHHHHHHHHHHHCCCCCHHCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2678100; 7766206 [H]