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The map label for this gene is cof [C]

Identifier: 53720925

GI number: 53720925

Start: 3933930

End: 3934772

Strand: Reverse

Name: cof [C]

Synonym: BPSL3315

Alternate gene names: 53720925

Gene position: 3934772-3933930 (Counterclockwise)

Preceding gene: 53720926

Following gene: 53720923

Centisome position: 96.57

GC content: 64.89

Gene sequence:

>843_bases
TTGCATCCTCCGATGTCCGCCATGTATAAAGCCATCGCTACCGATCTCGACGGAACCCTGCTCAATAGCGACCACCAGCT
CGATCCTTATACGATCGACACCGTGCGGCGGCTCGCGGGCAGCGGCGTGCCCTTCGTGATCGCGACGGGGCGCCACTATG
CGGATGTCGCGGGTATTCGCGACGTGCTCGGCATCCGTCCTTACCTGATCACGTCGAACGGCGCGCGCGTGCACGGGCCG
GACGACACGCGGATCCACGCGCAGGACGTGCCCGCCGACGCGGTGCGGCAACTGGTGCGGCCCGAGCTCGTCGGCACGCA
TGGCCGGGTGATCGTCAATCTGTTCACGAACGACGGCTGGCTGATCGATCGCGATGCGCCGCAACTGCTCGCATTCCATC
AGGATTCCGGATTTCGCTACGAAATCGTCGATATGCTGGCGCACGACGGCGCGGACATTGCGAAAGTGCTGTACATCGGC
GAGCCCGAGGATCTGGCCGTCGTCTCGGGCAATCTCGCGCGCCGGTTCGGCGACGCGCTGTACGTCACGTATTCGCTGCC
CGATTGCCTCGAGGTGATGACGGCGAATGTATCGAAGGGGCGCGCGCTGCGCGTCGTGCTCGAGCGGCTCGGCGTCGATC
CCGCCCACTGCGTGGCGTTCGGCGACAACATGAACGATATCGACCTGCTCGAGACGGCCGGGTATCCGTTCATGATGAAC
AACGCGAATCCCGACCTCGCCTTGCGCCTGCCGAAGGTGCCGCGGATCGGCAACAACTTCGAAGCGGGCGTCGCGCGCCA
TCTGCGCGCGCTGTTCGCGCTCGAGGATTCCATCGCGCACTGA

Upstream 100 bases:

>100_bases
CTGAACCCGATCGGAGCGGCGCGGCCCGCCGCGCGGGAATCGACGCCAGTGAGCGGCACGCGTCGTCCGACGATAAAATG
TCCGCTCTCTCCCGTGTCAG

Downstream 100 bases:

>100_bases
GCGTCGCCGGCCGCTCCGCCGATGGGTGCGGCCCGGCCGCATCCGCCACGAAAACGGGCGCCGCGGCGCCCGTTTTCGCT
TGTGTCCCGCTGCCGTCGGC

Product: Cof family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MHPPMSAMYKAIATDLDGTLLNSDHQLDPYTIDTVRRLAGSGVPFVIATGRHYADVAGIRDVLGIRPYLITSNGARVHGP
DDTRIHAQDVPADAVRQLVRPELVGTHGRVIVNLFTNDGWLIDRDAPQLLAFHQDSGFRYEIVDMLAHDGADIAKVLYIG
EPEDLAVVSGNLARRFGDALYVTYSLPDCLEVMTANVSKGRALRVVLERLGVDPAHCVAFGDNMNDIDLLETAGYPFMMN
NANPDLALRLPKVPRIGNNFEAGVARHLRALFALEDSIAH

Sequences:

>Translated_280_residues
MHPPMSAMYKAIATDLDGTLLNSDHQLDPYTIDTVRRLAGSGVPFVIATGRHYADVAGIRDVLGIRPYLITSNGARVHGP
DDTRIHAQDVPADAVRQLVRPELVGTHGRVIVNLFTNDGWLIDRDAPQLLAFHQDSGFRYEIVDMLAHDGADIAKVLYIG
EPEDLAVVSGNLARRFGDALYVTYSLPDCLEVMTANVSKGRALRVVLERLGVDPAHCVAFGDNMNDIDLLETAGYPFMMN
NANPDLALRLPKVPRIGNNFEAGVARHLRALFALEDSIAH
>Mature_280_residues
MHPPMSAMYKAIATDLDGTLLNSDHQLDPYTIDTVRRLAGSGVPFVIATGRHYADVAGIRDVLGIRPYLITSNGARVHGP
DDTRIHAQDVPADAVRQLVRPELVGTHGRVIVNLFTNDGWLIDRDAPQLLAFHQDSGFRYEIVDMLAHDGADIAKVLYIG
EPEDLAVVSGNLARRFGDALYVTYSLPDCLEVMTANVSKGRALRVVLERLGVDPAHCVAFGDNMNDIDLLETAGYPFMMN
NANPDLALRLPKVPRIGNNFEAGVARHLRALFALEDSIAH

Specific function: Unknown

COG id: COG0561

COG function: function code R; Predicted hydrolases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. Cof family [H]

Homologues:

Organism=Escherichia coli, GI48994981, Length=266, Percent_Identity=38.3458646616541, Blast_Score=186, Evalue=1e-48,
Organism=Escherichia coli, GI87081741, Length=261, Percent_Identity=37.1647509578544, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI2367265, Length=284, Percent_Identity=29.9295774647887, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006379
- InterPro:   IPR000150 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: NA

Molecular weight: Translated: 30641; Mature: 30641

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS01228 COF_1 ; PS01229 COF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPPMSAMYKAIATDLDGTLLNSDHQLDPYTIDTVRRLAGSGVPFVIATGRHYADVAGIR
CCCCHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHH
DVLGIRPYLITSNGARVHGPDDTRIHAQDVPADAVRQLVRPELVGTHGRVIVNLFTNDGW
HHHCCCCEEEECCCCEEECCCCCEEEECCCCHHHHHHHHCHHHCCCCCEEEEEEECCCCE
LIDRDAPQLLAFHQDSGFRYEIVDMLAHDGADIAKVLYIGEPEDLAVVSGNLARRFGDAL
EEECCCCCEEEEECCCCCEEHHHHHHHCCCCCEEEEEEECCCCCEEEECCHHHHHCCCEE
YVTYSLPDCLEVMTANVSKGRALRVVLERLGVDPAHCVAFGDNMNDIDLLETAGYPFMMN
EEEECCHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHEEEECCCCCCCHHHHHCCCCEEEC
NANPDLALRLPKVPRIGNNFEAGVARHLRALFALEDSIAH
CCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHPPMSAMYKAIATDLDGTLLNSDHQLDPYTIDTVRRLAGSGVPFVIATGRHYADVAGIR
CCCCHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHH
DVLGIRPYLITSNGARVHGPDDTRIHAQDVPADAVRQLVRPELVGTHGRVIVNLFTNDGW
HHHCCCCEEEECCCCEEECCCCCEEEECCCCHHHHHHHHCHHHCCCCCEEEEEEECCCCE
LIDRDAPQLLAFHQDSGFRYEIVDMLAHDGADIAKVLYIGEPEDLAVVSGNLARRFGDAL
EEECCCCCEEEEECCCCCEEHHHHHHHCCCCCEEEEEEECCCCCEEEECCHHHHHCCCEE
YVTYSLPDCLEVMTANVSKGRALRVVLERLGVDPAHCVAFGDNMNDIDLLETAGYPFMMN
EEEECCHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHEEEECCCCCCCHHHHHCCCCEEEC
NANPDLALRLPKVPRIGNNFEAGVARHLRALFALEDSIAH
CCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]