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The map label for this gene is thiO [H]

Identifier: 53720761

GI number: 53720761

Start: 3752027

End: 3753154

Strand: Reverse

Name: thiO [H]

Synonym: BPSL3154

Alternate gene names: 53720761

Gene position: 3753154-3752027 (Counterclockwise)

Preceding gene: 53720763

Following gene: 53720760

Centisome position: 92.11

GC content: 73.85

Gene sequence:

>1128_bases
ATGCGTGCGTCTGAATCCGATTTCGCGGTGCTGGGCGGCGGCCTCGTCGGCCGCCTGATCGCGTGGCGCCTCGCGGGCGC
GGGATACCGCGTGTCGCTCTACGAGCGCGGCGACGCGGCGGGCTCGGGCTCGGCCGCATGGGTCGCGGCCGCGATGCTCG
CGCCGCTCGCCGAAGCCGCGAGCGCCGAGCGCCTCATCACCGATCTCGGCGTCGCGTCGTTCGATCTGTGGCCGAGCTGG
CTTGCCGAGCTGCCGGAGCCCGTCTACTTCCAGCGCAACGGCACGCTTGTCGTCTGGCATCACGCGGACCGCGCGGAAGC
GCCGCTCTTCGAGCGCCGCGTGCGCGCGAACGCGAGCGCCGAGCTGCTCGACGGCGGCCTCGTCGCGCTCGCGGGCGCGC
AGCTCGACGCGGCCGAGCCGGCGCTCGCCGGCCGCTTCGCGCGCGGCCTGCTGCTGCCGCGCGAAGGCCAGCTCGACAAT
CGCCAGGCGCTGCGCGCGCTCGCCGCGGGCTTGGCCGAGCGCGGTGTCGACGTGCACTGGAATGCTGCCGTCGCGCCCGA
CGCCGCGCCCGCCGCGCGCATCACGATCGACTGCCGCGGGCTCGGCGCGAAGGCGCAGATGCCGGCGCTGCGCGGGATTC
GCGGCGAAGTCGCGCGCGTGCACGCGCCCGGCATCGGCCTCACGCGCCCCGTGCGACTCTTGCATCCGCGCTATCCGCTG
TACGTCGCGCCGAAGGAGAACGATCTCTACGTGATCGGCGCGACCGAGATCGAGGGCGAGGACATGTCGCCCGTCAGCGT
GCGCTCCGCGCTCGAATTGCTGAGCGCCGCGTTCTCCGTGCACCCGGCGTTCGGCGAGGCGCGTATTCTTGAACTGAACA
CGCAATGCCGGCCGACGCTGCCCGACCATCGTCCGGCGCTCGTGTGGGACGGCGGCGCGACGCTCGCGGTCAACGGCCTG
TACCGGCACGGCTTCATGATCGCGCCGGAAATCGCCGATGCCGCGGCCCGTTTCGCGCAGGCGCTCGTCGAGCGTACCGT
GAAGGATGCCGATACGTTCGCCGCGTGGCGGCGCGACGCGCGCTGGCCGGCGCTGCTGCAGCAGCGCGCGGCGCACGCGT
CCGCGTGA

Upstream 100 bases:

>100_bases
GTTCTTTTGCGTCGCTGCGAGCCGTCGGCCGCCGCGGCCTCCCCGGCTCCCGCAGCGAGCCGCTTCCCGATGACGGACAT
GACGGACGGATGCGATGAAC

Downstream 100 bases:

>100_bases
GCGCCGGACGAGCCGGCCAATTCCGATCAATCGACATCGACAGCCATCATGGACATCCAGGTCAACCAACAGACGTTCTC
GCTGCCCGACGGCGCGACGG

Product: putative thiamine biosynthesis oxidoreductase ThiO

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MRASESDFAVLGGGLVGRLIAWRLAGAGYRVSLYERGDAAGSGSAAWVAAAMLAPLAEAASAERLITDLGVASFDLWPSW
LAELPEPVYFQRNGTLVVWHHADRAEAPLFERRVRANASAELLDGGLVALAGAQLDAAEPALAGRFARGLLLPREGQLDN
RQALRALAAGLAERGVDVHWNAAVAPDAAPAARITIDCRGLGAKAQMPALRGIRGEVARVHAPGIGLTRPVRLLHPRYPL
YVAPKENDLYVIGATEIEGEDMSPVSVRSALELLSAAFSVHPAFGEARILELNTQCRPTLPDHRPALVWDGGATLAVNGL
YRHGFMIAPEIADAAARFAQALVERTVKDADTFAAWRRDARWPALLQQRAAHASA

Sequences:

>Translated_375_residues
MRASESDFAVLGGGLVGRLIAWRLAGAGYRVSLYERGDAAGSGSAAWVAAAMLAPLAEAASAERLITDLGVASFDLWPSW
LAELPEPVYFQRNGTLVVWHHADRAEAPLFERRVRANASAELLDGGLVALAGAQLDAAEPALAGRFARGLLLPREGQLDN
RQALRALAAGLAERGVDVHWNAAVAPDAAPAARITIDCRGLGAKAQMPALRGIRGEVARVHAPGIGLTRPVRLLHPRYPL
YVAPKENDLYVIGATEIEGEDMSPVSVRSALELLSAAFSVHPAFGEARILELNTQCRPTLPDHRPALVWDGGATLAVNGL
YRHGFMIAPEIADAAARFAQALVERTVKDADTFAAWRRDARWPALLQQRAAHASA
>Mature_375_residues
MRASESDFAVLGGGLVGRLIAWRLAGAGYRVSLYERGDAAGSGSAAWVAAAMLAPLAEAASAERLITDLGVASFDLWPSW
LAELPEPVYFQRNGTLVVWHHADRAEAPLFERRVRANASAELLDGGLVALAGAQLDAAEPALAGRFARGLLLPREGQLDN
RQALRALAAGLAERGVDVHWNAAVAPDAAPAARITIDCRGLGAKAQMPALRGIRGEVARVHAPGIGLTRPVRLLHPRYPL
YVAPKENDLYVIGATEIEGEDMSPVSVRSALELLSAAFSVHPAFGEARILELNTQCRPTLPDHRPALVWDGGATLAVNGL
YRHGFMIAPEIADAAARFAQALVERTVKDADTFAAWRRDARWPALLQQRAAHASA

Specific function: May have amino acid oxidase activity in the biosynthesis of thiazole when cysteine gives its thiol group to be inserted into the thiazole molecule and the rest of the molecule is deaminated to give pyruvic acid and ammonia [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR012727 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: NA

Molecular weight: Translated: 40001; Mature: 40001

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRASESDFAVLGGGLVGRLIAWRLAGAGYRVSLYERGDAAGSGSAAWVAAAMLAPLAEAA
CCCCCCCCEEECCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
SAERLITDLGVASFDLWPSWLAELPEPVYFQRNGTLVVWHHADRAEAPLFERRVRANASA
HHHHHHHHCCCHHHHCCHHHHHHCCCCEEEECCCCEEEEECCCCCCCCHHHHHHHCCCCH
ELLDGGLVALAGAQLDAAEPALAGRFARGLLLPREGQLDNRQALRALAAGLAERGVDVHW
HHHCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEE
NAAVAPDAAPAARITIDCRGLGAKAQMPALRGIRGEVARVHAPGIGLTRPVRLLHPRYPL
CCEECCCCCCCEEEEEEECCCCCCCCCCHHHCCCCCEEEEECCCCCCCCCHHHHCCCCCE
YVAPKENDLYVIGATEIEGEDMSPVSVRSALELLSAAFSVHPAFGEARILELNTQCRPTL
EECCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCC
PDHRPALVWDGGATLAVNGLYRHGFMIAPEIADAAARFAQALVERTVKDADTFAAWRRDA
CCCCCEEEECCCCEEEEECHHHCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RWPALLQQRAAHASA
CCHHHHHHHHHHCCC
>Mature Secondary Structure
MRASESDFAVLGGGLVGRLIAWRLAGAGYRVSLYERGDAAGSGSAAWVAAAMLAPLAEAA
CCCCCCCCEEECCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
SAERLITDLGVASFDLWPSWLAELPEPVYFQRNGTLVVWHHADRAEAPLFERRVRANASA
HHHHHHHHCCCHHHHCCHHHHHHCCCCEEEECCCCEEEEECCCCCCCCHHHHHHHCCCCH
ELLDGGLVALAGAQLDAAEPALAGRFARGLLLPREGQLDNRQALRALAAGLAERGVDVHW
HHHCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEE
NAAVAPDAAPAARITIDCRGLGAKAQMPALRGIRGEVARVHAPGIGLTRPVRLLHPRYPL
CCEECCCCCCCEEEEEEECCCCCCCCCCHHHCCCCCEEEEECCCCCCCCCHHHHCCCCCE
YVAPKENDLYVIGATEIEGEDMSPVSVRSALELLSAAFSVHPAFGEARILELNTQCRPTL
EECCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCC
PDHRPALVWDGGATLAVNGLYRHGFMIAPEIADAAARFAQALVERTVKDADTFAAWRRDA
CCCCCEEEECCCCEEEEECHHHCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RWPALLQQRAAHASA
CCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371431 [H]