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The map label for this gene is mltA [H]

Identifier: 53720655

GI number: 53720655

Start: 3636374

End: 3637492

Strand: Reverse

Name: mltA [H]

Synonym: BPSL3046

Alternate gene names: 53720655

Gene position: 3637492-3636374 (Counterclockwise)

Preceding gene: 53720656

Following gene: 53720649

Centisome position: 89.27

GC content: 70.33

Gene sequence:

>1119_bases
ATGGGTTTTAGCCGGCGGCTTGCCGGGTGGGCGGCGGCTGTCGCGGCCGCGGCGCTTCTCGCCGCATGTGTCGGCTCGCC
GGTGCGGCAGGGGGCACGGCCCGCGGGTGCCGCGATCGTACCAGGACAGATCGCGGCGGCGCGACTCACGCCCGTCGCGT
GGCAGCAGGTGCCCGGCTGGCAGGACGACAGCCTGATCGGCGCGACGATCGCGCTGCGCCAGAACTGCGCGCGCCTCGCG
CGGCAGGCGAACTGGCAGCGCGCGTGCGCGGCCGCCATGCGGCTCGACGATCTCGATGTCGGCAGCGCCCGCACCTTCTT
CGAAACGTACTTCACGCCGTTCCAGTTCGCGAACAACGACGGCACGCTCGACGGCCTCGTGACGGGTTATTACGAGCCGC
TGCTGCACGGCTCGCGCGTGCGTCGCGGCCCGTATCAGTACGCGCTCTACCGCTGGCCGGCCGGCTACCGCGCGGGCGCG
TCGATGCCGGCGCGCGCGCAGCTCATGCGCTCGGGCGCGCTGAGCGGCAACGAGCTCGTTTGGGTCGACGATCCGATCGA
AGCGTTCTTTCTGCAGGTGCAGGGTTCCGGCCGCGTCGTTCTCGACGACGGCACGGTGATGCGCGTCGGCTACGGCGGCA
CGAACAACCAGCCGTACCGCTCGATCGGCAAGTGGCTGCTCGATCATGGCGAACTCGGCGCCGGGCAGGCGACGATGCAG
GGAATCAAGGCGTGGGCGCGCGCGAATCCGTCGCGGGTCGACGCGCTGCTCGACACGAATCCGCGTTTCGTGTTCTTCCG
TGAGATGCCTTCACAGGAGGACGTGCCGCACGGCGGCGCGGACGGGCCGGTCGGCGCGCTCGGCGTGCCGCTCACGCCGG
AGCGCTCGATTGCGGTCGACCCTTCGTCGATCCCGCTCGGCACGCCGGTGTTCCTGCAGACGACGCGCCCGATGACGAAT
GCGCCGCTCAATCGCCTCGTGTTCGCGCAGGATGTCGGAACGGCGATCAAGGGCGGCGTGCGGGCCGACTATTTCTGGGG
GCTCGGCGACGACGCGGGCGATCAGGCGGGGCGGATGAAGCAGAACGGACGGATGTGGCTGCTGTTTCCGAATTCGTGA

Upstream 100 bases:

>100_bases
GAGCAGGGCGAGCGCCAGCAACGATTCCAGCGCGAAGATGAGCATCGGGTATTGGTCGAGCAGATCGGACATGGCGGTTT
CCATCAACAACGGACATTGT

Downstream 100 bases:

>100_bases
TCCTGTGATCTCGTGATCGCGGCCGTGTGCGCGCGCGGCGAGCGTCAGGAGCCCTGCCCGCGGGCGTGATTGCATGAGCG
TTGTGTTTGAGTGGCAGACT

Product: putative outer membrane-bound lytic murein transglycosylase

Products: Muramic Acid Residue [C]

Alternate protein names: Mlt38; Murein hydrolase A [H]

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MGFSRRLAGWAAAVAAAALLAACVGSPVRQGARPAGAAIVPGQIAAARLTPVAWQQVPGWQDDSLIGATIALRQNCARLA
RQANWQRACAAAMRLDDLDVGSARTFFETYFTPFQFANNDGTLDGLVTGYYEPLLHGSRVRRGPYQYALYRWPAGYRAGA
SMPARAQLMRSGALSGNELVWVDDPIEAFFLQVQGSGRVVLDDGTVMRVGYGGTNNQPYRSIGKWLLDHGELGAGQATMQ
GIKAWARANPSRVDALLDTNPRFVFFREMPSQEDVPHGGADGPVGALGVPLTPERSIAVDPSSIPLGTPVFLQTTRPMTN
APLNRLVFAQDVGTAIKGGVRADYFWGLGDDAGDQAGRMKQNGRMWLLFPNS

Sequences:

>Translated_372_residues
MGFSRRLAGWAAAVAAAALLAACVGSPVRQGARPAGAAIVPGQIAAARLTPVAWQQVPGWQDDSLIGATIALRQNCARLA
RQANWQRACAAAMRLDDLDVGSARTFFETYFTPFQFANNDGTLDGLVTGYYEPLLHGSRVRRGPYQYALYRWPAGYRAGA
SMPARAQLMRSGALSGNELVWVDDPIEAFFLQVQGSGRVVLDDGTVMRVGYGGTNNQPYRSIGKWLLDHGELGAGQATMQ
GIKAWARANPSRVDALLDTNPRFVFFREMPSQEDVPHGGADGPVGALGVPLTPERSIAVDPSSIPLGTPVFLQTTRPMTN
APLNRLVFAQDVGTAIKGGVRADYFWGLGDDAGDQAGRMKQNGRMWLLFPNS
>Mature_371_residues
GFSRRLAGWAAAVAAAALLAACVGSPVRQGARPAGAAIVPGQIAAARLTPVAWQQVPGWQDDSLIGATIALRQNCARLAR
QANWQRACAAAMRLDDLDVGSARTFFETYFTPFQFANNDGTLDGLVTGYYEPLLHGSRVRRGPYQYALYRWPAGYRAGAS
MPARAQLMRSGALSGNELVWVDDPIEAFFLQVQGSGRVVLDDGTVMRVGYGGTNNQPYRSIGKWLLDHGELGAGQATMQG
IKAWARANPSRVDALLDTNPRFVFFREMPSQEDVPHGGADGPVGALGVPLTPERSIAVDPSSIPLGTPVFLQTTRPMTNA
PLNRLVFAQDVGTAIKGGVRADYFWGLGDDAGDQAGRMKQNGRMWLLFPNS

Specific function: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. Degrades murein glycan strands and insoluble, high-molecular weight murein sacculi [H]

COG id: COG2821

COG function: function code M; Membrane-bound lytic murein transglycosylase

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789179, Length=372, Percent_Identity=31.7204301075269, Blast_Score=136, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010611
- InterPro:   IPR014733
- InterPro:   IPR005300 [H]

Pfam domain/function: PF06725 3D; PF03562 MltA [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 39979; Mature: 39848

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFSRRLAGWAAAVAAAALLAACVGSPVRQGARPAGAAIVPGQIAAARLTPVAWQQVPGW
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCEECCCCHHHHHCCHHHHHHCCCC
QDDSLIGATIALRQNCARLARQANWQRACAAAMRLDDLDVGSARTFFETYFTPFQFANND
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCEEEECCC
GTLDGLVTGYYEPLLHGSRVRRGPYQYALYRWPAGYRAGASMPARAQLMRSGALSGNELV
CCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCEEE
WVDDPIEAFFLQVQGSGRVVLDDGTVMRVGYGGTNNQPYRSIGKWLLDHGELGAGQATMQ
EEECCCEEEEEEECCCCEEEEECCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCHHHHH
GIKAWARANPSRVDALLDTNPRFVFFREMPSQEDVPHGGADGPVGALGVPLTPERSIAVD
HHHHHHHCCHHHHHHEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEC
PSSIPLGTPVFLQTTRPMTNAPLNRLVFAQDVGTAIKGGVRADYFWGLGDDAGDQAGRMK
CCCCCCCCCEEEEECCCCCCCCHHHEEEHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHH
QNGRMWLLFPNS
HCCCEEEEECCC
>Mature Secondary Structure 
GFSRRLAGWAAAVAAAALLAACVGSPVRQGARPAGAAIVPGQIAAARLTPVAWQQVPGW
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCEECCCCHHHHHCCHHHHHHCCCC
QDDSLIGATIALRQNCARLARQANWQRACAAAMRLDDLDVGSARTFFETYFTPFQFANND
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCEEEECCC
GTLDGLVTGYYEPLLHGSRVRRGPYQYALYRWPAGYRAGASMPARAQLMRSGALSGNELV
CCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCEEE
WVDDPIEAFFLQVQGSGRVVLDDGTVMRVGYGGTNNQPYRSIGKWLLDHGELGAGQATMQ
EEECCCEEEEEEECCCCEEEEECCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCHHHHH
GIKAWARANPSRVDALLDTNPRFVFFREMPSQEDVPHGGADGPVGALGVPLTPERSIAVD
HHHHHHHCCHHHHHHEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEC
PSSIPLGTPVFLQTTRPMTNAPLNRLVFAQDVGTAIKGGVRADYFWGLGDDAGDQAGRMK
CCCCCCCCCEEEEECCCCCCCCHHHEEEHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHH
QNGRMWLLFPNS
HCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic [C]

General reaction: Cleavage Bond [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]