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The map label for this gene is tktA [H]

Identifier: 53720561

GI number: 53720561

Start: 3524452

End: 3526479

Strand: Reverse

Name: tktA [H]

Synonym: BPSL2953

Alternate gene names: 53720561

Gene position: 3526479-3524452 (Counterclockwise)

Preceding gene: 53720565

Following gene: 53720560

Centisome position: 86.55

GC content: 68.29

Gene sequence:

>2028_bases
ATGACGACTTCGTCTCCCGCCTCCACCACTCTGATGGCCAACGCGATCCGCGCGCTCGCGATGGACGCCGTCCAGCAAGC
GAACTCCGGCCACCCCGGCATGCCGATGGGCATGGCCGAGATCGGCGTCGCGCTGTGGTCGCGCCACCTGAAGCACAACC
CGACGAACCCGCATTGGGCCGACCGCGACCGCTTCGTGCTGTCGAACGGCCACGGCTCGATGCTGCTGTACTCGCTGCTG
CACCTGACGGGCTACGATCTGCCGATCGAAGAGCTGAAGAATTTCCGGCAATTGCATTCGAAGACGCCGGGCCACCCGGA
ATACGGGATCACGCCGGGCGTCGAGACGACGACGGGCCCGCTCGGCCAGGGCCTCGCGAACGCGGTCGGCATGGCGCTCG
GCGAGGCGCTGCTCGCCGCCGAGTTCAACCGCGACGACGCGAAGATCGTCGATCATCACACGTACGTGTTCGTCGGCGAC
GGCTGCCTGATGGAGGGCATCTCGCACGAAGCGTGCTCGCTCGCGGGCACGCTCAAGCTCAACAAGCTGATCGCGTTCTA
CGACGACAACGGGATCTCGATCGACGGCGACGTCGTCAACTGGTTCCACGACGACACGCCGAAGCGCTTCGAGGCGTACG
GCTGGAACGTGATTCCGAACGTGAACGGCCACGACGTCGACGCGGTCGATGCCGCGATCGCGAAGGCGAAGAGCGCGGAC
AAGCCGACGCTCATCTGCTGCAAGACGGTGATCGGCAAGGGCGCGGCGACGAAGGCGGGCGGCCACGACGTGCACGGCGC
GGCGCTCGGCGCGGAGGAAATCGCGAAGACGCGCGACGCGCTCGGCTGGAAGTGGGCGCCGTTCGTGATTCCGCAGGAAG
TCTACGCGGCGTGGGACGCGAAGGAAGCGGGCAAGCGCCGCGAAGGCGACTGGAACGCGGCGTTCGCGCAGTACCGCGCG
AAGTACCCGGCCGAGGCCGCCGAATTCGAGCGCCGCATGGCGGGCAAGCTGCCGGCCGACTGGGCCGAGAAGGCCGCGGC
GATCGTCGCCGGCGCGAACGAGCGCGGCGAGACGGTCGCGACGCGTAAGGCGTCGCAGCAGACGATCGAGGGCCTTGCCG
CCGTGCTGCCCGAGCTGCTCGGCGGCTCGGCCGACCTGACGGGCTCGAACCTCACGAACTGGAAGGCGTCGAAGGCGGTG
CGCGCGAATGCGCACGGTGCGGGCATCCAGTGGGGCAACCACATCAACTACGGCGTGCGCGAATTCGGCATGAGCGCCGC
GATCAACGGCCTCGTGCTGCACGGCGGCTACAAGCCGTTCGGCGGCACGTTCCTCACGTTCTCCGACTACAGCCGCAACG
CGCTGCGCGTCGCCGCGCTGATGAAGGTGCCGTCGATCTTCGTGTTCACGCACGATTCGATCGGCCTCGGCGAAGACGGG
CCGACGCACCAGTCGGTCGAGCACGTCGCGAGCCTGCGGCTGATTCCGAACCTCGACGTCTGGCGCCCGGCCGACACGGT
CGAGACGGCGGTCGCGTGGACCCACGCGGTCTCGCACCAGCACCCGTCGTGCCTGGTCTTCAGCCGCCAGAACCTCGCGT
TCAACGCGCGCACCGACGCGCAGCTCGCGAACATCGAGAAGGGCGGCTACGTGCTGCGCGACTGGGACGAAGAGATCGTC
GCGCGCAAGATCATCCTGATCGCGACGGGCTCGGAAGTGGAGCTCGCGATGAAGGCGGTCGAGCCGCTCGCGCAGCAGGG
GATCGCCGCGCGCGTCGTGTCGATGCCGTCGACCGACGTGTTCGACCGGCAGGACGCCGAGTACCGCGAGCGCGTGCTGC
CGCACGGCGTGCGCCGCGTCGCGATCGAAGCGGGCGTCACCGATTTCTGGCGCAAGTACGTGGGCCTCGAAGGCGGCGTG
GTCGGCATCGACACGTTCGGCGAGTCGGCTCCGGCTGGCGTGTTGTTCAAGCATTTCGGCTTCACGATCGAGCACGTGGT
CGAAACGGCGAAGGCGGTGCTCGCGTAA

Upstream 100 bases:

>100_bases
CGCCTCCCGCCGGCGCCGCACCGCGCGCCGGAAACGGTTGGCCCGCGAGCCTCGGATGCCGCCCGTGCCCCGTTTTCTCG
ACTCGTTCTCCGGACTCGAC

Downstream 100 bases:

>100_bases
CCCATTCGACGCCCGGGCGGCCGTGCCCCGCGCCGGCCGGGCGCGCGTGAAGCTGCACGAAGTATTTTTTCAGCCATCAG
GAGATACATCATGACGATTC

Product: transketolase

Products: NA

Alternate protein names: TK 1 [H]

Number of amino acids: Translated: 675; Mature: 674

Protein sequence:

>675_residues
MTTSSPASTTLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVALWSRHLKHNPTNPHWADRDRFVLSNGHGSMLLYSLL
HLTGYDLPIEELKNFRQLHSKTPGHPEYGITPGVETTTGPLGQGLANAVGMALGEALLAAEFNRDDAKIVDHHTYVFVGD
GCLMEGISHEACSLAGTLKLNKLIAFYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIPNVNGHDVDAVDAAIAKAKSAD
KPTLICCKTVIGKGAATKAGGHDVHGAALGAEEIAKTRDALGWKWAPFVIPQEVYAAWDAKEAGKRREGDWNAAFAQYRA
KYPAEAAEFERRMAGKLPADWAEKAAAIVAGANERGETVATRKASQQTIEGLAAVLPELLGGSADLTGSNLTNWKASKAV
RANAHGAGIQWGNHINYGVREFGMSAAINGLVLHGGYKPFGGTFLTFSDYSRNALRVAALMKVPSIFVFTHDSIGLGEDG
PTHQSVEHVASLRLIPNLDVWRPADTVETAVAWTHAVSHQHPSCLVFSRQNLAFNARTDAQLANIEKGGYVLRDWDEEIV
ARKIILIATGSEVELAMKAVEPLAQQGIAARVVSMPSTDVFDRQDAEYRERVLPHGVRRVAIEAGVTDFWRKYVGLEGGV
VGIDTFGESAPAGVLFKHFGFTIEHVVETAKAVLA

Sequences:

>Translated_675_residues
MTTSSPASTTLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVALWSRHLKHNPTNPHWADRDRFVLSNGHGSMLLYSLL
HLTGYDLPIEELKNFRQLHSKTPGHPEYGITPGVETTTGPLGQGLANAVGMALGEALLAAEFNRDDAKIVDHHTYVFVGD
GCLMEGISHEACSLAGTLKLNKLIAFYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIPNVNGHDVDAVDAAIAKAKSAD
KPTLICCKTVIGKGAATKAGGHDVHGAALGAEEIAKTRDALGWKWAPFVIPQEVYAAWDAKEAGKRREGDWNAAFAQYRA
KYPAEAAEFERRMAGKLPADWAEKAAAIVAGANERGETVATRKASQQTIEGLAAVLPELLGGSADLTGSNLTNWKASKAV
RANAHGAGIQWGNHINYGVREFGMSAAINGLVLHGGYKPFGGTFLTFSDYSRNALRVAALMKVPSIFVFTHDSIGLGEDG
PTHQSVEHVASLRLIPNLDVWRPADTVETAVAWTHAVSHQHPSCLVFSRQNLAFNARTDAQLANIEKGGYVLRDWDEEIV
ARKIILIATGSEVELAMKAVEPLAQQGIAARVVSMPSTDVFDRQDAEYRERVLPHGVRRVAIEAGVTDFWRKYVGLEGGV
VGIDTFGESAPAGVLFKHFGFTIEHVVETAKAVLA
>Mature_674_residues
TTSSPASTTLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVALWSRHLKHNPTNPHWADRDRFVLSNGHGSMLLYSLLH
LTGYDLPIEELKNFRQLHSKTPGHPEYGITPGVETTTGPLGQGLANAVGMALGEALLAAEFNRDDAKIVDHHTYVFVGDG
CLMEGISHEACSLAGTLKLNKLIAFYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIPNVNGHDVDAVDAAIAKAKSADK
PTLICCKTVIGKGAATKAGGHDVHGAALGAEEIAKTRDALGWKWAPFVIPQEVYAAWDAKEAGKRREGDWNAAFAQYRAK
YPAEAAEFERRMAGKLPADWAEKAAAIVAGANERGETVATRKASQQTIEGLAAVLPELLGGSADLTGSNLTNWKASKAVR
ANAHGAGIQWGNHINYGVREFGMSAAINGLVLHGGYKPFGGTFLTFSDYSRNALRVAALMKVPSIFVFTHDSIGLGEDGP
THQSVEHVASLRLIPNLDVWRPADTVETAVAWTHAVSHQHPSCLVFSRQNLAFNARTDAQLANIEKGGYVLRDWDEEIVA
RKIILIATGSEVELAMKAVEPLAQQGIAARVVSMPSTDVFDRQDAEYRERVLPHGVRRVAIEAGVTDFWRKYVGLEGGVV
GIDTFGESAPAGVLFKHFGFTIEHVVETAKAVLA

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=607, Percent_Identity=27.1828665568369, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI4507521, Length=607, Percent_Identity=27.1828665568369, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI133778974, Length=263, Percent_Identity=33.0798479087452, Blast_Score=109, Evalue=9e-24,
Organism=Escherichia coli, GI48994911, Length=671, Percent_Identity=63.6363636363636, Blast_Score=878, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=666, Percent_Identity=61.4114114114114, Blast_Score=824, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17539652, Length=680, Percent_Identity=26.0294117647059, Blast_Score=153, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6325331, Length=672, Percent_Identity=49.702380952381, Blast_Score=614, Evalue=1e-176,
Organism=Saccharomyces cerevisiae, GI6319593, Length=674, Percent_Identity=45.6973293768546, Blast_Score=557, Evalue=1e-159,
Organism=Drosophila melanogaster, GI24666278, Length=263, Percent_Identity=34.2205323193916, Blast_Score=125, Evalue=1e-28,
Organism=Drosophila melanogaster, GI45551847, Length=309, Percent_Identity=32.3624595469256, Blast_Score=122, Evalue=8e-28,
Organism=Drosophila melanogaster, GI45550715, Length=309, Percent_Identity=32.3624595469256, Blast_Score=122, Evalue=8e-28,
Organism=Drosophila melanogaster, GI24645119, Length=260, Percent_Identity=33.0769230769231, Blast_Score=102, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 72695; Mature: 72564

Theoretical pI: Translated: 6.48; Mature: 6.48

Prosite motif: PS00801 TRANSKETOLASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSSPASTTLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVALWSRHLKHNPTNPHWA
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
DRDRFVLSNGHGSMLLYSLLHLTGYDLPIEELKNFRQLHSKTPGHPEYGITPGVETTTGP
CCCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
LGQGLANAVGMALGEALLAAEFNRDDAKIVDHHTYVFVGDGCLMEGISHEACSLAGTLKL
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECEEEEEECCCHHHHCCCHHHHHHHHHEEE
NKLIAFYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIPNVNGHDVDAVDAAIAKAKSAD
EEEEEEECCCCCEECCCEEECCCCCCCCHHHHCCCEECCCCCCCCCHHHHHHHHHHCCCC
KPTLICCKTVIGKGAATKAGGHDVHGAALGAEEIAKTRDALGWKWAPFVIPQEVYAAWDA
CCEEEEEHHHHCCCCCCCCCCCCCCHHHCCHHHHHHHHHHCCCCCCCCCCCHHHHHHCCH
KEAGKRREGDWNAAFAQYRAKYPAEAAEFERRMAGKLPADWAEKAAAIVAGANERGETVA
HHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHEEEEECCCCCCCCHH
TRKASQQTIEGLAAVLPELLGGSADLTGSNLTNWKASKAVRANAHGAGIQWGNHINYGVR
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCHH
EFGMSAAINGLVLHGGYKPFGGTFLTFSDYSRNALRVAALMKVPSIFVFTHDSIGLGEDG
HHCHHHHCCCEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHCCEEEEEECCCCCCCCCC
PTHQSVEHVASLRLIPNLDVWRPADTVETAVAWTHAVSHQHPSCLVFSRQNLAFNARTDA
CCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCEEECCCCC
QLANIEKGGYVLRDWDEEIVARKIILIATGSEVELAMKAVEPLAQQGIAARVVSMPSTDV
HHHCCCCCCEEEECCHHHHHHCEEEEEEECCHHHHHHHHHHHHHHCCHHEEEEECCCCCC
FDRQDAEYRERVLPHGVRRVAIEAGVTDFWRKYVGLEGGVVGIDTFGESAPAGVLFKHFG
CCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHC
FTIEHVVETAKAVLA
CHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTSSPASTTLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVALWSRHLKHNPTNPHWA
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
DRDRFVLSNGHGSMLLYSLLHLTGYDLPIEELKNFRQLHSKTPGHPEYGITPGVETTTGP
CCCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
LGQGLANAVGMALGEALLAAEFNRDDAKIVDHHTYVFVGDGCLMEGISHEACSLAGTLKL
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECEEEEEECCCHHHHCCCHHHHHHHHHEEE
NKLIAFYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIPNVNGHDVDAVDAAIAKAKSAD
EEEEEEECCCCCEECCCEEECCCCCCCCHHHHCCCEECCCCCCCCCHHHHHHHHHHCCCC
KPTLICCKTVIGKGAATKAGGHDVHGAALGAEEIAKTRDALGWKWAPFVIPQEVYAAWDA
CCEEEEEHHHHCCCCCCCCCCCCCCHHHCCHHHHHHHHHHCCCCCCCCCCCHHHHHHCCH
KEAGKRREGDWNAAFAQYRAKYPAEAAEFERRMAGKLPADWAEKAAAIVAGANERGETVA
HHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHEEEEECCCCCCCCHH
TRKASQQTIEGLAAVLPELLGGSADLTGSNLTNWKASKAVRANAHGAGIQWGNHINYGVR
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCHH
EFGMSAAINGLVLHGGYKPFGGTFLTFSDYSRNALRVAALMKVPSIFVFTHDSIGLGEDG
HHCHHHHCCCEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHCCEEEEEECCCCCCCCCC
PTHQSVEHVASLRLIPNLDVWRPADTVETAVAWTHAVSHQHPSCLVFSRQNLAFNARTDA
CCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCEEECCCCC
QLANIEKGGYVLRDWDEEIVARKIILIATGSEVELAMKAVEPLAQQGIAARVVSMPSTDV
HHHCCCCCCEEEECCHHHHHHCEEEEEEECCHHHHHHHHHHHHHHCCHHEEEEECCCCCC
FDRQDAEYRERVLPHGVRRVAIEAGVTDFWRKYVGLEGGVVGIDTFGESAPAGVLFKHFG
CCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHC
FTIEHVVETAKAVLA
CHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA