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The map label for this gene is dtd [H]

Identifier: 53720511

GI number: 53720511

Start: 3472953

End: 3473432

Strand: Reverse

Name: dtd [H]

Synonym: BPSL2903

Alternate gene names: 53720511

Gene position: 3473432-3472953 (Counterclockwise)

Preceding gene: 53720512

Following gene: 53720510

Centisome position: 85.25

GC content: 72.5

Gene sequence:

>480_bases
GTGCGTGACGCGGACGCGCGCATGATCGCCTTGATCCAGCGCGTGAAGCGCGCCGACGTGCGCGTGGGCGAGCGCGTGAC
GGGCGAGATCGGCCCCGGCCTGCTCGCGCTCGTGTGCGCGGAGCGCGGCGACACCGAGGCGGCCGCCGACAAGCTGCTCG
CGAAGGTGCTCGGCTACCGCGTGTTCAGTGACGCGGCGGGCAAGATGAACCTGCCCGTGTCGAACCTCGACGGCGCGGGA
CGCGCGGGCGGGCTGTTGCTTGTGTCGCAGTTCACGCTCGCCGCCGACACGAACAGCGGCCTGCGCCCGAGCTTCACGCC
CGCCGCGCCGCCCGACGAGGGCGAGCGCCTGTTCGACTACTTCGTGCGTCGGGCCCGCGAGCGCCATCCGATCGTCGCGA
CGGGAGAGTTCGGCGCCGACATGCAGGTGTCGCTCGTCAACGACGGCCCCGTGACGTTCTGGCTGCAGACGCGCGCCTGA

Upstream 100 bases:

>100_bases
CGCTTCGCGCGCGTGACGCTTACCGCATGAGCGCGCGCATCGCCGCTTGGCCGGGCATGCCGCGCGCGGTGCGCGGCGCC
GCGCGTGGCCGCCGCGCCGC

Downstream 100 bases:

>100_bases
TGCGCCCTTGACGCTCCGATTCGAGACCGCACCGATGCCCACGACGCAGATTCTCTTCATTCGCCATGGCGAGACGGCCT
GGAACCGCATCAAGCGGATT

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MRDADARMIALIQRVKRADVRVGERVTGEIGPGLLALVCAERGDTEAAADKLLAKVLGYRVFSDAAGKMNLPVSNLDGAG
RAGGLLLVSQFTLAADTNSGLRPSFTPAAPPDEGERLFDYFVRRARERHPIVATGEFGADMQVSLVNDGPVTFWLQTRA

Sequences:

>Translated_159_residues
MRDADARMIALIQRVKRADVRVGERVTGEIGPGLLALVCAERGDTEAAADKLLAKVLGYRVFSDAAGKMNLPVSNLDGAG
RAGGLLLVSQFTLAADTNSGLRPSFTPAAPPDEGERLFDYFVRRARERHPIVATGEFGADMQVSLVNDGPVTFWLQTRA
>Mature_159_residues
MRDADARMIALIQRVKRADVRVGERVTGEIGPGLLALVCAERGDTEAAADKLLAKVLGYRVFSDAAGKMNLPVSNLDGAG
RAGGLLLVSQFTLAADTNSGLRPSFTPAAPPDEGERLFDYFVRRARERHPIVATGEFGADMQVSLVNDGPVTFWLQTRA

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine [H]

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family [H]

Homologues:

Organism=Homo sapiens, GI30795227, Length=154, Percent_Identity=37.012987012987, Blast_Score=90, Evalue=7e-19,
Organism=Escherichia coli, GI1790320, Length=149, Percent_Identity=62.4161073825503, Blast_Score=179, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI115533292, Length=154, Percent_Identity=35.7142857142857, Blast_Score=79, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6319982, Length=152, Percent_Identity=38.1578947368421, Blast_Score=89, Evalue=4e-19,
Organism=Drosophila melanogaster, GI281361569, Length=152, Percent_Identity=36.8421052631579, Blast_Score=87, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003732 [H]

Pfam domain/function: PF02580 Tyr_Deacylase [H]

EC number: NA

Molecular weight: Translated: 17070; Mature: 17070

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDADARMIALIQRVKRADVRVGERVTGEIGPGLLALVCAERGDTEAAADKLLAKVLGYR
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHEEHHHHCCCCCHHHHHHHHHHHHHHH
VFSDAAGKMNLPVSNLDGAGRAGGLLLVSQFTLAADTNSGLRPSFTPAAPPDEGERLFDY
HHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHH
FVRRARERHPIVATGEFGADMQVSLVNDGPVTFWLQTRA
HHHHHHHCCCEEEECCCCCCEEEEEECCCCEEEEEEECC
>Mature Secondary Structure
MRDADARMIALIQRVKRADVRVGERVTGEIGPGLLALVCAERGDTEAAADKLLAKVLGYR
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHEEHHHHCCCCCHHHHHHHHHHHHHHH
VFSDAAGKMNLPVSNLDGAGRAGGLLLVSQFTLAADTNSGLRPSFTPAAPPDEGERLFDY
HHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHH
FVRRARERHPIVATGEFGADMQVSLVNDGPVTFWLQTRA
HHHHHHHCCCEEEECCCCCCEEEEEECCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA