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The map label for this gene is hmpA [H]

Identifier: 53720448

GI number: 53720448

Start: 3400797

End: 3402005

Strand: Reverse

Name: hmpA [H]

Synonym: BPSL2840

Alternate gene names: 53720448

Gene position: 3402005-3400797 (Counterclockwise)

Preceding gene: 53720449

Following gene: 53720443

Centisome position: 83.49

GC content: 67.82

Gene sequence:

>1209_bases
ATGACGCAGATGACCGCCGAGCAAATGGCCCGAGTGAAAGCGACCGCCCCGGTTCTCGCGGAGCACGGCGCGACGATCAC
GAAGCACTTTTATCAGCGGATGTTCGGGCGCCACCCCGAGCTGAAGAACGTTTTCAACCAGACGCACCAGAAGACGGGCA
GCCAGCCGGAGACGCTCGCGAAGGCGGTCTATGCATACGCGGCGAACATCGACAATCTCGGCGCGCTCGGCGGCGCCGTG
TCGCGGATCGCGCACAAGCACGCGAGCCTGAACATCCGGCCGGAGCACTACCCGATCGTCGGCGAGAACCTGCTCGCCTC
GATCGTCGAGGTGCTCGGCGACGCGGTGGACGCGGACACGCTCGAAGCGTGGCGCATCGCGTACGGCCAGCTCGCCGCGA
TCCTGATCGGCGCGGAGGCGAACCTGTACGAGAACGCCGCATGGAGCGGCTTCCGCCCGTTCAAGGTCGCGAAGAAGGTG
CGCGAGAGCGACGAGATCACGTCGTTCTACCTGACGCCCGCCGACGGCGGCGCGGCGCCCGGGTTCGAGCCGGGCCAGTA
CATCTCGGTGAAGCGTTTCGTCGGCGACATGGGCGTCGATCAGCCGCGTCAGTACAGCCTGTCCGACGCGCCGCACGGCA
AGTGGCTGCGCATCTCGGTCAAGCGCGAGGCGGGGCACAGCGAGGCGGTGCCGGCGGGCAAGGTGTCGACGCTGATGCAC
GACGGCGTCGACGTCGATTCGGTCGTCGAAGTCACCGCGCCGATGGGCGATTTCACGCTGAACCGCCATGCGACGACGCC
CGTCGTGCTGATTTCGGGCGGCGTCGGGATCACGCCGATGATGTCGATGGCGTCGACGCTCGTCGCAGCGGGCAGCGAGC
GCGAAGTGCGTTTCCTGCACGCGTGCCGCGCGGCGAACGTGCATGCGTTCCGCGACTGGCTGAACGACACGACGGACGCG
CATCCGAACGTGAAGCGCGCGGTGTTCTACGAGGTGGTCGGCCCGAACGACCGCGTGGGCGTCGATCACGACCACGAAGG
CCGGATCACGCCGGCTGCGCTCGAGCGCCACGCGCTCGTGCCGGACGCCGATTACTACATCTGCGGGCCGATCGCGTTCA
TGAAGCAGCAGCGCGACGCGCTCGTTGCGCTCGGCGTCGCGCCGGAGCGCGTGCAGACGGAAATCTTCGGTTCGGGCGCG
CTCGAATGA

Upstream 100 bases:

>100_bases
GCAATCGCGGGCCCGTTATGGCGAGGTGCGACAATTTGACCGCCGGAGGTGCGCTCATAAAGATGTATCGTTTGCGAATG
TTTAACGGAGGAATACTTTC

Downstream 100 bases:

>100_bases
CGAAGCGCCGGCGAACGACACGGGTTCGCTGAAGCGAAACGGCAAAGCCCGGCGCCATGCGCCGGGCTTTTTCTTGGGCG
AGGGCCGCGCGGGAGCCGGA

Product: flavohemoprotein

Products: NA

Alternate protein names: Flavohemoglobin; Hemoglobin-like protein; Nitric oxide dioxygenase; NO oxygenase; NOD [H]

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MTQMTAEQMARVKATAPVLAEHGATITKHFYQRMFGRHPELKNVFNQTHQKTGSQPETLAKAVYAYAANIDNLGALGGAV
SRIAHKHASLNIRPEHYPIVGENLLASIVEVLGDAVDADTLEAWRIAYGQLAAILIGAEANLYENAAWSGFRPFKVAKKV
RESDEITSFYLTPADGGAAPGFEPGQYISVKRFVGDMGVDQPRQYSLSDAPHGKWLRISVKREAGHSEAVPAGKVSTLMH
DGVDVDSVVEVTAPMGDFTLNRHATTPVVLISGGVGITPMMSMASTLVAAGSEREVRFLHACRAANVHAFRDWLNDTTDA
HPNVKRAVFYEVVGPNDRVGVDHDHEGRITPAALERHALVPDADYYICGPIAFMKQQRDALVALGVAPERVQTEIFGSGA
LE

Sequences:

>Translated_402_residues
MTQMTAEQMARVKATAPVLAEHGATITKHFYQRMFGRHPELKNVFNQTHQKTGSQPETLAKAVYAYAANIDNLGALGGAV
SRIAHKHASLNIRPEHYPIVGENLLASIVEVLGDAVDADTLEAWRIAYGQLAAILIGAEANLYENAAWSGFRPFKVAKKV
RESDEITSFYLTPADGGAAPGFEPGQYISVKRFVGDMGVDQPRQYSLSDAPHGKWLRISVKREAGHSEAVPAGKVSTLMH
DGVDVDSVVEVTAPMGDFTLNRHATTPVVLISGGVGITPMMSMASTLVAAGSEREVRFLHACRAANVHAFRDWLNDTTDA
HPNVKRAVFYEVVGPNDRVGVDHDHEGRITPAALERHALVPDADYYICGPIAFMKQQRDALVALGVAPERVQTEIFGSGA
LE
>Mature_401_residues
TQMTAEQMARVKATAPVLAEHGATITKHFYQRMFGRHPELKNVFNQTHQKTGSQPETLAKAVYAYAANIDNLGALGGAVS
RIAHKHASLNIRPEHYPIVGENLLASIVEVLGDAVDADTLEAWRIAYGQLAAILIGAEANLYENAAWSGFRPFKVAKKVR
ESDEITSFYLTPADGGAAPGFEPGQYISVKRFVGDMGVDQPRQYSLSDAPHGKWLRISVKREAGHSEAVPAGKVSTLMHD
GVDVDSVVEVTAPMGDFTLNRHATTPVVLISGGVGITPMMSMASTLVAAGSEREVRFLHACRAANVHAFRDWLNDTTDAH
PNVKRAVFYEVVGPNDRVGVDHDHEGRITPAALERHALVPDADYYICGPIAFMKQQRDALVALGVAPERVQTEIFGSGAL
E

Specific function: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a centra

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1788903, Length=399, Percent_Identity=42.6065162907268, Blast_Score=298, Evalue=3e-82,
Organism=Escherichia coli, GI1787658, Length=260, Percent_Identity=25.7692307692308, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321673, Length=405, Percent_Identity=37.037037037037, Blast_Score=237, Evalue=2e-63,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR012292
- InterPro:   IPR009050
- InterPro:   IPR000971
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00042 Globin; PF00175 NAD_binding_1 [H]

EC number: =1.14.12.17 [H]

Molecular weight: Translated: 43556; Mature: 43425

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS01033 GLOBIN ; PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQMTAEQMARVKATAPVLAEHGATITKHFYQRMFGRHPELKNVFNQTHQKTGSQPETLA
CCCCCHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHH
KAVYAYAANIDNLGALGGAVSRIAHKHASLNIRPEHYPIVGENLLASIVEVLGDAVDADT
HHHHHHHCCCCCHHHHHHHHHHHHHHHCCEEECCCCCCCCCHHHHHHHHHHHHCCCCCHH
LEAWRIAYGQLAAILIGAEANLYENAAWSGFRPFKVAKKVRESDEITSFYLTPADGGAAP
HHHHHHHHHHEEEEEECCCCCHHCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCC
GFEPGQYISVKRFVGDMGVDQPRQYSLSDAPHGKWLRISVKREAGHSEAVPAGKVSTLMH
CCCCCCEEHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHH
DGVDVDSVVEVTAPMGDFTLNRHATTPVVLISGGVGITPMMSMASTLVAAGSEREVRFLH
CCCCHHHHHHHHCCCCCCEECCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHH
ACRAANVHAFRDWLNDTTDAHPNVKRAVFYEVVGPNDRVGVDHDHEGRITPAALERHALV
HHHHCCHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHCCCC
PDADYYICGPIAFMKQQRDALVALGVAPERVQTEIFGSGALE
CCCCEEEECHHHHHHHHCCEEEEECCCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TQMTAEQMARVKATAPVLAEHGATITKHFYQRMFGRHPELKNVFNQTHQKTGSQPETLA
CCCCHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHH
KAVYAYAANIDNLGALGGAVSRIAHKHASLNIRPEHYPIVGENLLASIVEVLGDAVDADT
HHHHHHHCCCCCHHHHHHHHHHHHHHHCCEEECCCCCCCCCHHHHHHHHHHHHCCCCCHH
LEAWRIAYGQLAAILIGAEANLYENAAWSGFRPFKVAKKVRESDEITSFYLTPADGGAAP
HHHHHHHHHHEEEEEECCCCCHHCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCC
GFEPGQYISVKRFVGDMGVDQPRQYSLSDAPHGKWLRISVKREAGHSEAVPAGKVSTLMH
CCCCCCEEHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHH
DGVDVDSVVEVTAPMGDFTLNRHATTPVVLISGGVGITPMMSMASTLVAAGSEREVRFLH
CCCCHHHHHHHHCCCCCCEECCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHH
ACRAANVHAFRDWLNDTTDAHPNVKRAVFYEVVGPNDRVGVDHDHEGRITPAALERHALV
HHHHCCHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHCCCC
PDADYYICGPIAFMKQQRDALVALGVAPERVQTEIFGSGALE
CCCCEEEECHHHHHHHHCCEEEEECCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]