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The map label for this gene is pcaR [H]

Identifier: 53720356

GI number: 53720356

Start: 3288720

End: 3289544

Strand: Reverse

Name: pcaR [H]

Synonym: BPSL2746

Alternate gene names: 53720356

Gene position: 3289544-3288720 (Counterclockwise)

Preceding gene: 53720358

Following gene: 53720355

Centisome position: 80.73

GC content: 70.42

Gene sequence:

>825_bases
ATGTTTTGCAAATTGAGCCCAGTGTATCACCGCATGAATTTTTCGACCATCGATGCCGACACGCTCGACGAACGCAAGTT
CGTCGTCGCCCTCGCCCGGGGGCTGGATCTGCTGCGCGCGTTCCGGCCCGGCGAGACGATGCTCGGCAACCGCGATTTCG
CCGAGCGCACCGGGCTGCCGAAGGCGACCGTCAACCGGCTCGCATATACGCTGACGGTGCTCGGCTATCTGCGCTACGAC
GACGCGCTCGGCAAGTACGCGCTCGACGCGGGCGTGCTGTCGCTCGGCTACGCGTTGCTCGCGGGCTCGGACACGCTCGC
GCTCGCGCGGCCGCACATGCAGGCGCTCGCGCGCGAGATCGGCGCGGCGGTGTCGCTCGGCTGCCGCGACGGTCTCGACA
TGATCTACCTGGAGACGATTCGCAGCGAGACGGCGCTGACGCTCGGGCTGGCGTCCGGCTCGCGGCTGTCGATGCTGACG
AGCTCGATGGGGCGCGCGTATCTCGCCGTGCAGCCCCCCGACGCGCGCGCGGCGCTCTTCGCCGAGCTGCGCAAGACGGT
GGGGAAGGGGCGGGCGGGGGCGGCGCTCGTCGACGCGGCGCGGCGCGCGGCCGATGCGTTCGCGGCCGACGGCTGCTGCT
ATTCGTTTGGCGACTGGCACGGCGACGTGAACGCGGCCGCCGTGCCGTTTCGCGAGCCGCGCGAAGGGCGCTGGCTGATT
CTCAGTTGCAGCGGGCCGGCGTCGTCGATGGGCGAGGACGTGTTCCGCAACCGGATTGGCCCGAAGCTGAAGGTGCTCGC
GCGGCGGCTCGGAGAACCGGGCTGA

Upstream 100 bases:

>100_bases
GGTGAGCTGCTGGTCGAGCAGCAGCGGATCGTCCCAGTGGAAGGTTGCGGCAGCCATCTCGTCATCTCCTCGCTTGACTA
TAGTTCCGCTGTGCGGAACA

Downstream 100 bases:

>100_bases
GCCCGCGAGCGGCGGCCGGCGAGCCGCTCGAAGGCGGTCGAAGCGTCGAAGCGTCGAAGCGTCGAAGCGTCGAAGCGTCG
AAGCGTCGAAGCGTCGAAGC

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MFCKLSPVYHRMNFSTIDADTLDERKFVVALARGLDLLRAFRPGETMLGNRDFAERTGLPKATVNRLAYTLTVLGYLRYD
DALGKYALDAGVLSLGYALLAGSDTLALARPHMQALAREIGAAVSLGCRDGLDMIYLETIRSETALTLGLASGSRLSMLT
SSMGRAYLAVQPPDARAALFAELRKTVGKGRAGAALVDAARRAADAFAADGCCYSFGDWHGDVNAAAVPFREPREGRWLI
LSCSGPASSMGEDVFRNRIGPKLKVLARRLGEPG

Sequences:

>Translated_274_residues
MFCKLSPVYHRMNFSTIDADTLDERKFVVALARGLDLLRAFRPGETMLGNRDFAERTGLPKATVNRLAYTLTVLGYLRYD
DALGKYALDAGVLSLGYALLAGSDTLALARPHMQALAREIGAAVSLGCRDGLDMIYLETIRSETALTLGLASGSRLSMLT
SSMGRAYLAVQPPDARAALFAELRKTVGKGRAGAALVDAARRAADAFAADGCCYSFGDWHGDVNAAAVPFREPREGRWLI
LSCSGPASSMGEDVFRNRIGPKLKVLARRLGEPG
>Mature_274_residues
MFCKLSPVYHRMNFSTIDADTLDERKFVVALARGLDLLRAFRPGETMLGNRDFAERTGLPKATVNRLAYTLTVLGYLRYD
DALGKYALDAGVLSLGYALLAGSDTLALARPHMQALAREIGAAVSLGCRDGLDMIYLETIRSETALTLGLASGSRLSMLT
SSMGRAYLAVQPPDARAALFAELRKTVGKGRAGAALVDAARRAADAFAADGCCYSFGDWHGDVNAAAVPFREPREGRWLI
LSCSGPASSMGEDVFRNRIGPKLKVLARRLGEPG

Specific function: Positive regulator of all genes within the pca regulon, pcaBDC, pcaIJ and pcaF. Also required for the chemotactic response to aromatic compounds [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI87082359, Length=231, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012794
- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29466; Mature: 29466

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED ; PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFCKLSPVYHRMNFSTIDADTLDERKFVVALARGLDLLRAFRPGETMLGNRDFAERTGLP
CCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHCCCCCHHHHCCCC
KATVNRLAYTLTVLGYLRYDDALGKYALDAGVLSLGYALLAGSDTLALARPHMQALAREI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
GAAVSLGCRDGLDMIYLETIRSETALTLGLASGSRLSMLTSSMGRAYLAVQPPDARAALF
HHHHCCCCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCEEEEECCCCHHHHHH
AELRKTVGKGRAGAALVDAARRAADAFAADGCCYSFGDWHGDVNAAAVPFREPREGRWLI
HHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCEECCCCCCCCCCEEE
LSCSGPASSMGEDVFRNRIGPKLKVLARRLGEPG
EECCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MFCKLSPVYHRMNFSTIDADTLDERKFVVALARGLDLLRAFRPGETMLGNRDFAERTGLP
CCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHCCCCCHHHHCCCC
KATVNRLAYTLTVLGYLRYDDALGKYALDAGVLSLGYALLAGSDTLALARPHMQALAREI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
GAAVSLGCRDGLDMIYLETIRSETALTLGLASGSRLSMLTSSMGRAYLAVQPPDARAALF
HHHHCCCCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCEEEEECCCCHHHHHH
AELRKTVGKGRAGAALVDAARRAADAFAADGCCYSFGDWHGDVNAAAVPFREPREGRWLI
HHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCEECCCCCCCCCCEEE
LSCSGPASSMGEDVFRNRIGPKLKVLARRLGEPG
EECCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083169 [H]