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The map label for this gene is rmlC [H]

Identifier: 53720294

GI number: 53720294

Start: 3211503

End: 3212054

Strand: Reverse

Name: rmlC [H]

Synonym: BPSL2684

Alternate gene names: 53720294

Gene position: 3212054-3211503 (Counterclockwise)

Preceding gene: 53720295

Following gene: 53720293

Centisome position: 78.83

GC content: 55.8

Gene sequence:

>552_bases
ATGGCCATCCAAGTAACTGCTACCGCTTTGCCGGAAGTCAAGATTATCGAACCGAAGGTATTCGGCGATGCTCGCGGATT
CTTCTTCGAGAGCTTCAATGCTCGAGAATTTACAGAACTCGTTGAGCCGGGCATCGAATTCGTTCAGGACAATCACTCCC
GATCCGCCCGTGGCGTGCTTCGCGGCCTGCACTATCAAATTCAGCACGCGCAAGGGAAACTCGTGCGTGTAGTCGACGGC
GAAGTGTTCGACGTCGCGGTCGATGTCCGGAGGAGTTCGCCCAATTTCGGTAAGTGGGTTGGCGTACGGCTGTCTGCGGA
GAACAAGCGGCAGCTTTGGGTGCCGGCGGGCTTCGCGCATGGCTTCGTTGTACTGAGCGAATCAGCGGATTTTCTGTACA
AGACGACCGACTATTGGTATCCGGAGTTTGAGCGGAGCATCCTTTGGAGCGACAAGCAAATCGGTATCGAATGGCCGATT
GATCGGGAGCCGCTTGTTGCTGCAAAGGATGCCGCGGGCAAGGCGATTAGCGAAGCCGAGGTCTATGCATGA

Upstream 100 bases:

>100_bases
GGCAGTGGATCGACGCGGAACAACTGCTCAAGCTCGCACAGCCTTTGTCGAAAAATGGCTATGGCCAGTACCTGAAAAAC
ATTCTTACGGATCAAGTCGC

Downstream 100 bases:

>100_bases
AGATTTTGGTGACGGGGGCAAACGGCCAAGTGGGCTGGGAACTCGCTCGGAGTCTGGCGGTATTGGGGCAAGTTGTCCCG
CTCACGCGTGAGCAGGCCGA

Product: dTDP-6-deoxy-D-glucose-3,5 epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MAIQVTATALPEVKIIEPKVFGDARGFFFESFNAREFTELVEPGIEFVQDNHSRSARGVLRGLHYQIQHAQGKLVRVVDG
EVFDVAVDVRRSSPNFGKWVGVRLSAENKRQLWVPAGFAHGFVVLSESADFLYKTTDYWYPEFERSILWSDKQIGIEWPI
DREPLVAAKDAAGKAISEAEVYA

Sequences:

>Translated_183_residues
MAIQVTATALPEVKIIEPKVFGDARGFFFESFNAREFTELVEPGIEFVQDNHSRSARGVLRGLHYQIQHAQGKLVRVVDG
EVFDVAVDVRRSSPNFGKWVGVRLSAENKRQLWVPAGFAHGFVVLSESADFLYKTTDYWYPEFERSILWSDKQIGIEWPI
DREPLVAAKDAAGKAISEAEVYA
>Mature_182_residues
AIQVTATALPEVKIIEPKVFGDARGFFFESFNAREFTELVEPGIEFVQDNHSRSARGVLRGLHYQIQHAQGKLVRVVDGE
VFDVAVDVRRSSPNFGKWVGVRLSAENKRQLWVPAGFAHGFVVLSESADFLYKTTDYWYPEFERSILWSDKQIGIEWPID
REPLVAAKDAAGKAISEAEVYA

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=169, Percent_Identity=55.6213017751479, Blast_Score=199, Evalue=7e-53,
Organism=Caenorhabditis elegans, GI17550412, Length=159, Percent_Identity=50.314465408805, Blast_Score=152, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 20648; Mature: 20516

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIQVTATALPEVKIIEPKVFGDARGFFFESFNAREFTELVEPGIEFVQDNHSRSARGVL
CEEEEEECCCCCEEEECCEECCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHH
RGLHYQIQHAQGKLVRVVDGEVFDVAVDVRRSSPNFGKWVGVRLSAENKRQLWVPAGFAH
HHHHHEEECCCCCEEEEECCCEEEEEEEEECCCCCCCEEEEEEECCCCCEEEEEECCCCC
GFVVLSESADFLYKTTDYWYPEFERSILWSDKQIGIEWPIDREPLVAAKDAAGKAISEAE
EEEEEECCCCEEEEECCCCCCCCCCEEEECCCCCCEECCCCCCCCEEECCCCCCCCCCCC
VYA
CCC
>Mature Secondary Structure 
AIQVTATALPEVKIIEPKVFGDARGFFFESFNAREFTELVEPGIEFVQDNHSRSARGVL
EEEEEECCCCCEEEECCEECCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHH
RGLHYQIQHAQGKLVRVVDGEVFDVAVDVRRSSPNFGKWVGVRLSAENKRQLWVPAGFAH
HHHHHEEECCCCCEEEEECCCEEEEEEEEECCCCCCCEEEEEEECCCCCEEEEEECCCCC
GFVVLSESADFLYKTTDYWYPEFERSILWSDKQIGIEWPIDREPLVAAKDAAGKAISEAE
EEEEEECCCCEEEEECCCCCCCCCCEEEECCCCCCEECCCCCCCCEEECCCCCCCCCCCC
VYA
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]