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The map label for this gene is wbiH [H]

Identifier: 53720283

GI number: 53720283

Start: 3198565

End: 3199575

Strand: Reverse

Name: wbiH [H]

Synonym: BPSL2673

Alternate gene names: 53720283

Gene position: 3199575-3198565 (Counterclockwise)

Preceding gene: 53720284

Following gene: 53720282

Centisome position: 78.53

GC content: 59.94

Gene sequence:

>1011_bases
ATGTTCCAACTGAATTTGACCATCTTGTCCGCGATGGCGTTCGCATCGATCGCTGCGATCGTCACCGCGCTTATTCTCAA
ATGGCTTCTCGCGAGCGGATGGGCATGGCGGCTGGCGACTGATGTGCCGAACGCTCGCTCGATGCACACACGGCCGACGC
CGCGTATGGGCGGCTGGGGGATCGTGCCGGTTGGCGCGGTGGCCATTGGGATTGCCGCGCCGCATCTATGGGGAATTGTC
GCGGCGATGCTGTTTCTGGCGATCGTCTCTCATATCGACGACCGTCGGGGGCTACCCGCGCGGGTTCGATTCGCTGCCCA
CCTCATCGCGTCCGCGGCGATTGCCGCGTTGTATTCGGGGGGCTTGGCATGGTTCTGGATTCCCATCGTCGCCGTCGGGC
TCGCGTGGCTGATCAACCTGTATAACTTCATGGACGGCGCAGATGGCCTTGCCGGGGGAATGACCGTCTTCGGTTTCGGC
AGCTATGCGTTTGCAGCACTCGCAGGACCCCATCCATCTGTCGGATTGGGTTGGGCGTGTGCGGCGATTGCGGGTGCGGC
GGCGGGATTCCTGCTCCTCAACTTCCATCCGGCCAAGCTTTTCCTGGGCGATGCGGGTTCGATTTCGCTCGGTTTGCTCG
CCGGGGCGTTCGGCTATTGGGGATGGCGTCATGCGGTCTGGCCGCTGTGGTTTCCGCTCGTTGTCTTTGCACCGTTTATT
GCCGATGCATCTGTAACATTGTTGCGACGTTTGTTACGAAGGGAAAAGTTCTGGGAAGCACATCGAGAGCATTATTATCA
GCGCATGGTGCGCTTGGGCGTCGGGCACGCGCGGACAGCGCTCTGTTGGTACGCGACCATGCTGGTCGGCGCCGTCGTGT
CGCTTTCGGTATTGGCATGTTCTACCGCGGTCCAGTGGATGACTATCGCCGCTTGGGGTTCGATCCTGTTTCTCTTGGGC
GTAGCCATCGATGTGTGCTGGAGTCGCTTCCAAATACTTACATCAAAATAA

Upstream 100 bases:

>100_bases
TGCTCGACTGGCGTCCGCCGCGCTCGAGCGAAGAGGGGCTCGCCGAAACGGCGTGCTGGTTCAAGTCGCTGGGCCGACGC
TAGTCGCCGGAAGAGGCACG

Downstream 100 bases:

>100_bases
CGCAACATGACGCGAGCATTTTGCCCGAAGGCTTCGTGGCTTTCCCTGGGCGCCTTTCTGTTCGATCTGATGGCGGTCGT
ATGCGCGTGGCTGATCGCGT

Product: putative undecaprenyl phosphate N-acetylglucosaminyltransferase

Products: Undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine; UMP [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-Phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MFQLNLTILSAMAFASIAAIVTALILKWLLASGWAWRLATDVPNARSMHTRPTPRMGGWGIVPVGAVAIGIAAPHLWGIV
AAMLFLAIVSHIDDRRGLPARVRFAAHLIASAAIAALYSGGLAWFWIPIVAVGLAWLINLYNFMDGADGLAGGMTVFGFG
SYAFAALAGPHPSVGLGWACAAIAGAAAGFLLLNFHPAKLFLGDAGSISLGLLAGAFGYWGWRHAVWPLWFPLVVFAPFI
ADASVTLLRRLLRREKFWEAHREHYYQRMVRLGVGHARTALCWYATMLVGAVVSLSVLACSTAVQWMTIAAWGSILFLLG
VAIDVCWSRFQILTSK

Sequences:

>Translated_336_residues
MFQLNLTILSAMAFASIAAIVTALILKWLLASGWAWRLATDVPNARSMHTRPTPRMGGWGIVPVGAVAIGIAAPHLWGIV
AAMLFLAIVSHIDDRRGLPARVRFAAHLIASAAIAALYSGGLAWFWIPIVAVGLAWLINLYNFMDGADGLAGGMTVFGFG
SYAFAALAGPHPSVGLGWACAAIAGAAAGFLLLNFHPAKLFLGDAGSISLGLLAGAFGYWGWRHAVWPLWFPLVVFAPFI
ADASVTLLRRLLRREKFWEAHREHYYQRMVRLGVGHARTALCWYATMLVGAVVSLSVLACSTAVQWMTIAAWGSILFLLG
VAIDVCWSRFQILTSK
>Mature_336_residues
MFQLNLTILSAMAFASIAAIVTALILKWLLASGWAWRLATDVPNARSMHTRPTPRMGGWGIVPVGAVAIGIAAPHLWGIV
AAMLFLAIVSHIDDRRGLPARVRFAAHLIASAAIAALYSGGLAWFWIPIVAVGLAWLINLYNFMDGADGLAGGMTVFGFG
SYAFAALAGPHPSVGLGWACAAIAGAAAGFLLLNFHPAKLFLGDAGSISLGLLAGAFGYWGWRHAVWPLWFPLVVFAPFI
ADASVTLLRRLLRREKFWEAHREHYYQRMVRLGVGHARTALCWYATMLVGAVVSLSVLACSTAVQWMTIAAWGSILFLLG
VAIDVCWSRFQILTSK

Specific function: Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to t

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.13 [C]

Molecular weight: Translated: 36186; Mature: 36186

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQLNLTILSAMAFASIAAIVTALILKWLLASGWAWRLATDVPNARSMHTRPTPRMGGWG
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCC
IVPVGAVAIGIAAPHLWGIVAAMLFLAIVSHIDDRRGLPARVRFAAHLIASAAIAALYSG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHC
GLAWFWIPIVAVGLAWLINLYNFMDGADGLAGGMTVFGFGSYAFAALAGPHPSVGLGWAC
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHEECHHHHHHHHCCCCCCCCHHHHH
AAIAGAAAGFLLLNFHPAKLFLGDAGSISLGLLAGAFGYWGWRHAVWPLWFPLVVFAPFI
HHHHHHHHHHHHEEECHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADASVTLLRRLLRREKFWEAHREHYYQRMVRLGVGHARTALCWYATMLVGAVVSLSVLAC
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
STAVQWMTIAAWGSILFLLGVAIDVCWSRFQILTSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFQLNLTILSAMAFASIAAIVTALILKWLLASGWAWRLATDVPNARSMHTRPTPRMGGWG
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCC
IVPVGAVAIGIAAPHLWGIVAAMLFLAIVSHIDDRRGLPARVRFAAHLIASAAIAALYSG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHC
GLAWFWIPIVAVGLAWLINLYNFMDGADGLAGGMTVFGFGSYAFAALAGPHPSVGLGWAC
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHEECHHHHHHHHCCCCCCCCHHHHH
AAIAGAAAGFLLLNFHPAKLFLGDAGSISLGLLAGAFGYWGWRHAVWPLWFPLVVFAPFI
HHHHHHHHHHHHEEECHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADASVTLLRRLLRREKFWEAHREHYYQRMVRLGVGHARTALCWYATMLVGAVVSLSVLAC
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
STAVQWMTIAAWGSILFLLGVAIDVCWSRFQILTSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Undecaprenyl phosphate; UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine [C]

Specific reaction: Undecaprenyl phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine --> Undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UMP [C]

General reaction: Substituted phospho group transfer [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12101296; 9384377 [H]