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The map label for this gene is pgm [H]

Identifier: 53720276

GI number: 53720276

Start: 3189170

End: 3190564

Strand: Reverse

Name: pgm [H]

Synonym: BPSL2666

Alternate gene names: 53720276

Gene position: 3190564-3189170 (Counterclockwise)

Preceding gene: 53720282

Following gene: 53720275

Centisome position: 78.3

GC content: 68.32

Gene sequence:

>1395_bases
ATGATCTCCCAATCCATCTTCAAGGCATACGATATTCGGGGCGTGATCGGCAAGACGCTCGACGCCGACGTCGCGCGCTC
GATCGGCCGCGCATTCGGCAGCGAAGTGCGCGCGCAGGGCGGCGACGCGGTCGTCGTCGCGCGCGACGGCCGGCTCTCGG
GGCCCGAGCTCGTCGGCGCGCTCGCGGACGGGCTGCGCGCGGCGGGCGTCGATGTCGTCGACGTCGGCATGGTGCCGACG
CCCGTCGGCTACTTCGCGGCGAGCGTGCCGCTCGCGCTGTCGGGCGGCGAGCGCCGCGTCGATTCGTGCATCGTCGTCAC
GGGCAGCCACAATCCGCCCGACTACAACGGTTTCAAGATGGTCCTGCGCGGCGCCGCGATTTACGGCGACCAGATCCAGG
GCCTGTACAAGCGCATCGTCGACGCGCGTTTCGAGACCGGCAACGGTTCGTATGAGCGATACGATGTCGCCGATCAATAC
GTTGAGCGCATCGTCGGCGACATCAGGCTCGCGCGGCCGCTGAAGCTCGTCGTCGATGCGGGCAACGGCGTCGCGGGCCC
GCTCGCGACGCGCCTGTTCAAGGCGCTCGGCTGCGAACTCGTCGAGCTCTTCACCGACATCGACGGCAACTTCCCGAACC
ACCACCCGGACCCGGCGCACCCGGAGAACCTGCAGGACGTGATCGCGAAGCTGAAGACGACCGATGCCGAGATCGGCTTC
GCGTTCGACGGCGACGGCGACCGCCTCGGCGTCGTCACGAAGGACGGCCAGATCATCTATCCGGACCGCCAGCTGATGCT
GTTCGCCGAGGAAGTGCTGTCGCGCAACCCGGGCGCGCAGATCATCTACGACGTGAAGTGCACGCGCAATCTCGCGCAGT
GGGTGCGCGAGAAGGGCGGCGAGCCGCTGATGTGGAAGACGGGCCACTCGCTCGTGAAGGCGAAGCTGCGCGAGACGGGC
GCGCCGCTCGCGGGCGAGATGAGCGGCCACGTGTTCTTCAAGGATCGCTGGTACGGCTTCGACGACGGCCTCTACACGGG
CGCGCGCCTGCTCGAGATCCTCGCGCGCGCGGCCGATCCGAGCGCGCTGCTCAACGGCTTGCCGAACGCGGTGTCGACGC
CCGAGCTGCAATTGAAGCTCGACGAAGGCGAGAACGTGAAGCTGATCGACAAGCTGCGCGCCGACGCGAAGTTCGACGGC
GCGGACGAGGTCGTGACGATCGACGGTCTGCGCGTCGAGTATCCGGACGGCTTCGGTCTCGCGCGTTCGTCGAACACGAC
GCCCGTGGTCGTGCTGCGCTTCGAGGCGAGCTCCGACGCGGCGCTCGCGCGGATCCAGGACGATTTCCGGCGCGCGCTGA
AGGCGGCGAAGCCGGACGCGAACCTGCCGTTCTGA

Upstream 100 bases:

>100_bases
GCGTTGCGTTGCCCCCTCGCCGGTCGGTTCGGGCGAGGATTTTTTACGCATTCGCGTTGAGGCGGCCAAATTTTTTATGG
ACGACACAGAGAGTGAATCG

Downstream 100 bases:

>100_bases
GCTTGACGGCGGCGCGGCGCGCGCCGGGCGCGGCGTGCCCGAGCTTGCGCTGACGCAAGCCTTGTCCAAAAAGCGGCGAC
GCATGCGTGCGTTCGCCGCT

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MISQSIFKAYDIRGVIGKTLDADVARSIGRAFGSEVRAQGGDAVVVARDGRLSGPELVGALADGLRAAGVDVVDVGMVPT
PVGYFAASVPLALSGGERRVDSCIVVTGSHNPPDYNGFKMVLRGAAIYGDQIQGLYKRIVDARFETGNGSYERYDVADQY
VERIVGDIRLARPLKLVVDAGNGVAGPLATRLFKALGCELVELFTDIDGNFPNHHPDPAHPENLQDVIAKLKTTDAEIGF
AFDGDGDRLGVVTKDGQIIYPDRQLMLFAEEVLSRNPGAQIIYDVKCTRNLAQWVREKGGEPLMWKTGHSLVKAKLRETG
APLAGEMSGHVFFKDRWYGFDDGLYTGARLLEILARAADPSALLNGLPNAVSTPELQLKLDEGENVKLIDKLRADAKFDG
ADEVVTIDGLRVEYPDGFGLARSSNTTPVVVLRFEASSDAALARIQDDFRRALKAAKPDANLPF

Sequences:

>Translated_464_residues
MISQSIFKAYDIRGVIGKTLDADVARSIGRAFGSEVRAQGGDAVVVARDGRLSGPELVGALADGLRAAGVDVVDVGMVPT
PVGYFAASVPLALSGGERRVDSCIVVTGSHNPPDYNGFKMVLRGAAIYGDQIQGLYKRIVDARFETGNGSYERYDVADQY
VERIVGDIRLARPLKLVVDAGNGVAGPLATRLFKALGCELVELFTDIDGNFPNHHPDPAHPENLQDVIAKLKTTDAEIGF
AFDGDGDRLGVVTKDGQIIYPDRQLMLFAEEVLSRNPGAQIIYDVKCTRNLAQWVREKGGEPLMWKTGHSLVKAKLRETG
APLAGEMSGHVFFKDRWYGFDDGLYTGARLLEILARAADPSALLNGLPNAVSTPELQLKLDEGENVKLIDKLRADAKFDG
ADEVVTIDGLRVEYPDGFGLARSSNTTPVVVLRFEASSDAALARIQDDFRRALKAAKPDANLPF
>Mature_464_residues
MISQSIFKAYDIRGVIGKTLDADVARSIGRAFGSEVRAQGGDAVVVARDGRLSGPELVGALADGLRAAGVDVVDVGMVPT
PVGYFAASVPLALSGGERRVDSCIVVTGSHNPPDYNGFKMVLRGAAIYGDQIQGLYKRIVDARFETGNGSYERYDVADQY
VERIVGDIRLARPLKLVVDAGNGVAGPLATRLFKALGCELVELFTDIDGNFPNHHPDPAHPENLQDVIAKLKTTDAEIGF
AFDGDGDRLGVVTKDGQIIYPDRQLMLFAEEVLSRNPGAQIIYDVKCTRNLAQWVREKGGEPLMWKTGHSLVKAKLRETG
APLAGEMSGHVFFKDRWYGFDDGLYTGARLLEILARAADPSALLNGLPNAVSTPELQLKLDEGENVKLIDKLRADAKFDG
ADEVVTIDGLRVEYPDGFGLARSSNTTPVVVLRFEASSDAALARIQDDFRRALKAAKPDANLPF

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1788361, Length=457, Percent_Identity=37.199124726477, Blast_Score=234, Evalue=7e-63,
Organism=Escherichia coli, GI1789566, Length=482, Percent_Identity=24.4813278008299, Blast_Score=85, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 50084; Mature: 50084

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISQSIFKAYDIRGVIGKTLDADVARSIGRAFGSEVRAQGGDAVVVARDGRLSGPELVGA
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHH
LADGLRAAGVDVVDVGMVPTPVGYFAASVPLALSGGERRVDSCIVVTGSHNPPDYNGFKM
HHHHHHHCCCCEEECCCCCCCHHHHHHCCCEEECCCCCCCCEEEEEECCCCCCCCCHHHH
VLRGAAIYGDQIQGLYKRIVDARFETGNGSYERYDVADQYVERIVGDIRLARPLKLVVDA
HHHHHHHCCHHHHHHHHHHHHCEEECCCCCCEEHHHHHHHHHHHHHHHHHCCCEEEEEEC
GNGVAGPLATRLFKALGCELVELFTDIDGNFPNHHPDPAHPENLQDVIAKLKTTDAEIGF
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEE
AFDGDGDRLGVVTKDGQIIYPDRQLMLFAEEVLSRNPGAQIIYDVKCTRNLAQWVREKGG
EECCCCCEEEEEECCCEEECCCHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHCCC
EPLMWKTGHSLVKAKLRETGAPLAGEMSGHVFFKDRWYGFDDGLYTGARLLEILARAADP
CCEEECCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCH
SALLNGLPNAVSTPELQLKLDEGENVKLIDKLRADAKFDGADEVVTIDGLRVEYPDGFGL
HHHHHCCCCCCCCCCEEEEECCCCCEEHHHHHHCCCCCCCCCCEEEECCEEEECCCCCCC
ARSSNTTPVVVLRFEASSDAALARIQDDFRRALKAAKPDANLPF
CCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MISQSIFKAYDIRGVIGKTLDADVARSIGRAFGSEVRAQGGDAVVVARDGRLSGPELVGA
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHH
LADGLRAAGVDVVDVGMVPTPVGYFAASVPLALSGGERRVDSCIVVTGSHNPPDYNGFKM
HHHHHHHCCCCEEECCCCCCCHHHHHHCCCEEECCCCCCCCEEEEEECCCCCCCCCHHHH
VLRGAAIYGDQIQGLYKRIVDARFETGNGSYERYDVADQYVERIVGDIRLARPLKLVVDA
HHHHHHHCCHHHHHHHHHHHHCEEECCCCCCEEHHHHHHHHHHHHHHHHHCCCEEEEEEC
GNGVAGPLATRLFKALGCELVELFTDIDGNFPNHHPDPAHPENLQDVIAKLKTTDAEIGF
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEE
AFDGDGDRLGVVTKDGQIIYPDRQLMLFAEEVLSRNPGAQIIYDVKCTRNLAQWVREKGG
EECCCCCEEEEEECCCEEECCCHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHCCC
EPLMWKTGHSLVKAKLRETGAPLAGEMSGHVFFKDRWYGFDDGLYTGARLLEILARAADP
CCEEECCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCH
SALLNGLPNAVSTPELQLKLDEGENVKLIDKLRADAKFDGADEVVTIDGLRVEYPDGFGL
HHHHHCCCCCCCCCCEEEEECCCCCEEHHHHHHCCCCCCCCCCEEEECCEEEECCCCCCC
ARSSNTTPVVVLRFEASSDAALARIQDDFRRALKAAKPDANLPF
CCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157643; 8188595 [H]