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The map label for this gene is wzb [C]

Identifier: 53719901

GI number: 53719901

Start: 2758113

End: 2758592

Strand: Reverse

Name: wzb [C]

Synonym: BPSL2291

Alternate gene names: 53719901

Gene position: 2758592-2758113 (Counterclockwise)

Preceding gene: 53719902

Following gene: 53719900

Centisome position: 67.7

GC content: 69.38

Gene sequence:

>480_bases
ATGAAAAGCGTCGCGATCTGTTTCGTCTGCCTCGGCAATATCTGCCGCTCGCCCACCGCGGAAGGGGTGATGCGCCATCA
GGTGGCTGCAGCGGGGCTCGACGGGGCGATCGAGATCGATTCGGCCGGCACGGGCGACTGGCATGTCGGCGAAGCGCCCG
ACGCGCGCGCGCAGCAAGCGGCGCGTGCGCGGGGCTACGATCTGTCGGCGCTGCGGGCGCGGCAGATCGGCGACGCCGAT
TTCGAACGCTTCGATCTCGTGCTCGCGATGGACGGCGCCAATCTCGCGGCGTTGCGCAAGCGCTGCCCGCCGCAATATCG
GGGCAAGGTCCGGCTCCTGATGGAATTCGCGGGCGACGGCTCGGCCGGCGACATCGCCGATCCATATTTCGGCGGCGCGC
GCGGCTTCGAGCAGGTGCTCGATCAGTGCGAGGCCGCGTGCCGCGGCCTTCTCGACAGCCTGCGTGAAACGGCGCGCTGA

Upstream 100 bases:

>100_bases
GCGCTGTGACGCGGCACCCGGCGCAAGCGGGAATTGGCGCGCCTTTGTATAATGGCGCGTTATCCATTCGAGCGGTTCGC
CGCGCGTGTCCGGCTGCACG

Downstream 100 bases:

>100_bases
GGCGCCGCATACAACCCCTTTTAGCGGCAGGGATACTTGACTAAATTGGTCAAATATTTATACTTGACCAAAATCGTCAA
GATTGCTGCCCATTCAATAC

Product: low molecular weight phosphotyrosine protein phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MKSVAICFVCLGNICRSPTAEGVMRHQVAAAGLDGAIEIDSAGTGDWHVGEAPDARAQQAARARGYDLSALRARQIGDAD
FERFDLVLAMDGANLAALRKRCPPQYRGKVRLLMEFAGDGSAGDIADPYFGGARGFEQVLDQCEAACRGLLDSLRETAR

Sequences:

>Translated_159_residues
MKSVAICFVCLGNICRSPTAEGVMRHQVAAAGLDGAIEIDSAGTGDWHVGEAPDARAQQAARARGYDLSALRARQIGDAD
FERFDLVLAMDGANLAALRKRCPPQYRGKVRLLMEFAGDGSAGDIADPYFGGARGFEQVLDQCEAACRGLLDSLRETAR
>Mature_159_residues
MKSVAICFVCLGNICRSPTAEGVMRHQVAAAGLDGAIEIDSAGTGDWHVGEAPDARAQQAARARGYDLSALRARQIGDAD
FERFDLVLAMDGANLAALRKRCPPQYRGKVRLLMEFAGDGSAGDIADPYFGGARGFEQVLDQCEAACRGLLDSLRETAR

Specific function: Dephosphorylates Wzc. Required For The Extracellular Polysaccharide Colanic Acid Synthesis. Probably Involved In The Export Of Colanic Acid From The Cell To Medium. [C]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI6005988, Length=150, Percent_Identity=40, Blast_Score=109, Evalue=8e-25,
Organism=Homo sapiens, GI4757714, Length=150, Percent_Identity=38, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6325330, Length=155, Percent_Identity=33.5483870967742, Blast_Score=107, Evalue=6e-25,
Organism=Drosophila melanogaster, GI78706770, Length=152, Percent_Identity=41.4473684210526, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI78706772, Length=152, Percent_Identity=41.4473684210526, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI78706766, Length=147, Percent_Identity=37.4149659863946, Blast_Score=103, Evalue=5e-23,
Organism=Drosophila melanogaster, GI78706768, Length=147, Percent_Identity=37.4149659863946, Blast_Score=103, Evalue=5e-23,
Organism=Drosophila melanogaster, GI78711846, Length=149, Percent_Identity=38.255033557047, Blast_Score=97, Evalue=6e-21,
Organism=Drosophila melanogaster, GI78706764, Length=125, Percent_Identity=36.8, Blast_Score=91, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 16961; Mature: 16961

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSVAICFVCLGNICRSPTAEGVMRHQVAAAGLDGAIEIDSAGTGDWHVGEAPDARAQQA
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHH
ARARGYDLSALRARQIGDADFERFDLVLAMDGANLAALRKRCPPQYRGKVRLLMEFAGDG
HHHCCCCHHHHHHHHCCCCCHHHEEEEEEECCCCHHHHHHHCCCCCCCHHHHEEEECCCC
SAGDIADPYFGGARGFEQVLDQCEAACRGLLDSLRETAR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKSVAICFVCLGNICRSPTAEGVMRHQVAAAGLDGAIEIDSAGTGDWHVGEAPDARAQQA
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHH
ARARGYDLSALRARQIGDADFERFDLVLAMDGANLAALRKRCPPQYRGKVRLLMEFAGDG
HHHCCCCHHHHHHHHCCCCCHHHEEEEEEECCCCHHHHHHHCCCCCCCHHHHEEEECCCC
SAGDIADPYFGGARGFEQVLDQCEAACRGLLDSLRETAR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]