Click here to switch to the map view.

The map label for this gene is fdhA [H]

Identifier: 53719816

GI number: 53719816

Start: 2649224

End: 2651545

Strand: Reverse

Name: fdhA [H]

Synonym: BPSL2207

Alternate gene names: 53719816

Gene position: 2651545-2649224 (Counterclockwise)

Preceding gene: 53719817

Following gene: 53719814

Centisome position: 65.08

GC content: 68.22

Gene sequence:

>2322_bases
ATGGAGCATGCGATGGCAGTCGAGAAAACCGCCTGTATTCTGTGTTCGCGCAATTGCGGCCTTGTCGTCGACGTCACGGA
CGGCAAGTTCGCGAAGATCCGAGGCGACGACGATCATCCGGTTTCGAAAGGCTATCTGTGCCAGAAGGCCGCGCGTCTCA
CGTACTACCAGCATCACGACGATCGCCTCACGCACCCGCTGCGCCGCGAGCCCGACGGCAGCTTCGTGCGCGTCACATGG
GACGAGGCGCTCGACGACATCGCGCAGCGCCTCGTCGCGCTGCGCGAGCGGCATGGCGGCGACGCGTTCGCGTTCGTCGG
CGGGGGCGGGCAGGGCAACCACGTCGGCGGCGCGTACAGCCGGCAGTTGCTCGCCGCGATGCGCAGCCGCTACGCGTACA
ACGCGCTCGGCCAGGAGAAGACGGGCGACTTCTGGCTCAACGGGCGGCTGTTCGGCCGTCAGGACTGCCACACGACCGAG
GACATCGAGCATGCGGATTACGTGCTCGTCATCGGCGCGAATCCGTATCAGGCGCACGGGATTCCGAATGCGCGCGACAC
GCTGCGCGATCTGAAGAAGGATCCGGCGCGCACGCTCGTCGTCGTCGATCCGCGCCGCTCGGAGACGGCGAAGTTCGCCG
ATCTGCATCTGCAGGTGCGGCCGGGCGCGGACGCGTATCTGATGAGCGCGATGCTCGCGATCATGCTGCGCGACGGGCTG
TTCGACCGCGCGTTCATCGCGCAGCGCTGCACGGGCTTCGAGTTCGTCGAGCGCGTGCTGCGCGACGTGCCGATCGCCGA
ATACGCGCGCCGCGCGGACGTGCCGCTCGAGGACATCGAGCGCGTCGCGCACGGCTTCGCGACCGCGCGCGCGGCTTGCC
TGCGCATCGATCTCGGCATCCAGCACACGCTGCACACGACGCTCAACGGCTACCTCGAGAAGCTGCTGTTCCTGCTGACG
GGCCACTTCGGCAAGCGCGGCGGCAACAACCTGCATTCGTTCCTGCTGCCCGTCATCGGCCATACCGACGAGCGCGCGAT
CCGTCACGGCAAGCCGCTCAAGCGGACCGCGCATCACCGGATGTTTCCGATCGCGGGCATCTATCCGCCGAACATCCTGC
CCGACGAGATCGAGCGCGCGGGCGAGAAGCGCGTGCGCGCGGCGTTCGTCGACAGCGCGAATCCGGTCGTCACGTATGCC
GATACGAACGCATATGAACGCGCGTTCGGCAAGCTGGAGCTGCTCGTCGTGATCGACGTCGCGATGACCGAAACCGCGCG
CCTCGCGCATTACGTGCTGCCCGCCGCGTCGCAGTTCGAGAAGTGGGAGGCGACGGGCTTCAACCTCGAGTTCCCGGCGA
ACGCGTTTCATCTGCGCCATCCGCTGCTGCCGCCGCTCGGCGAGTCGCTGCCGGAGCCGGAGATCTATACGCGGCTGCTC
GAGAAGATGGGCGAGCTGCCGCGCCGCTTTCCGCTTCTGGAGCGCATCGCGCGGTTCGAGCCGCGCGCGTCGAAGCATCT
GGCCTACCTGGGCGCGCTCGGGATCGTGCTCGCGGCGAACAAGAAGTGGCAGCGTCACGCGGCGTCGATCGTCTATCGCA
CGCTCGGCCGCGCGTTGCCGGGCGACGCGGCGGCGAGCGCGCCGCTGCTGCCGCTCGCGATGCTGTACGCGCAGCGGCAT
TACGCGGCCGTGCGCCGCGCCGGATTTCGCGGCAATCGCGCGACGCTCGGCACGGCGCTCTTTCGCGCGATTCTCGAGCG
CCGCTCGGGGACGCTCATCAGCGTGCACGAATTCGACGAGATGTGGCGCTTCATCCGCCATCCGGACGCTCGCGTGCACC
TGCACATCCCGGAGATGATCGACGAGCTGCGCGCGCTCGCGACCGAGACGCCGCCCGGCGCCGACTATCCGTTCGTGCTG
ATGGCGGGCGAGCGGCGCGCGTACAACGCGAACCAGATTTATCGCGATCCGACGTGGCGCAAGGTCGATCCGCACGGCTC
GCTGCGGATTCATCCGGACGACGCGGCGGCGCTGGGTGTCGCGGACGGCGGCAAGCTCGTGTGCGCGTCGGCGACGGGCA
GCATCGAAGTCGTCGCCGAGCTCGACGATAGCGTGCGGCGCGGGATGGTCACGTTGCCGCACGGCTACGGCATGCGCTAC
AAGGGCGGGCCGCCCGTCGGTCCCGAGCTCAATCGCCTGACCTCGGGCGCGCATTGCGATCCGCTGTCGCGCACGCCTTA
TCACAAATATGTGCCCGTGCATTTGCGCGTCGTCGATACGCCGGTTGCCGCGCCCGCGACGCTCGAAGCCGAATCGGCTT
GA

Upstream 100 bases:

>100_bases
TGTTCGATTGACTCCGATCAATACATCGCATAACGTTCGTTACCGTAACGATCGTTATTTCATATTCATTCTTCCCCGAT
TCCGGCGGATGCGCCGGCAG

Downstream 100 bases:

>100_bases
TGGCGCGCGCGCTCGTGCGCCTTCGTGCAAGCGGCGGTGCAGGCTGACGTGCCGCCGCGTGCACGGCGGGATAGCGCATG
GTCGTTCGCGCGCCGGAACG

Product: putative molybdopterin oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 773; Mature: 773

Protein sequence:

>773_residues
MEHAMAVEKTACILCSRNCGLVVDVTDGKFAKIRGDDDHPVSKGYLCQKAARLTYYQHHDDRLTHPLRREPDGSFVRVTW
DEALDDIAQRLVALRERHGGDAFAFVGGGGQGNHVGGAYSRQLLAAMRSRYAYNALGQEKTGDFWLNGRLFGRQDCHTTE
DIEHADYVLVIGANPYQAHGIPNARDTLRDLKKDPARTLVVVDPRRSETAKFADLHLQVRPGADAYLMSAMLAIMLRDGL
FDRAFIAQRCTGFEFVERVLRDVPIAEYARRADVPLEDIERVAHGFATARAACLRIDLGIQHTLHTTLNGYLEKLLFLLT
GHFGKRGGNNLHSFLLPVIGHTDERAIRHGKPLKRTAHHRMFPIAGIYPPNILPDEIERAGEKRVRAAFVDSANPVVTYA
DTNAYERAFGKLELLVVIDVAMTETARLAHYVLPAASQFEKWEATGFNLEFPANAFHLRHPLLPPLGESLPEPEIYTRLL
EKMGELPRRFPLLERIARFEPRASKHLAYLGALGIVLAANKKWQRHAASIVYRTLGRALPGDAAASAPLLPLAMLYAQRH
YAAVRRAGFRGNRATLGTALFRAILERRSGTLISVHEFDEMWRFIRHPDARVHLHIPEMIDELRALATETPPGADYPFVL
MAGERRAYNANQIYRDPTWRKVDPHGSLRIHPDDAAALGVADGGKLVCASATGSIEVVAELDDSVRRGMVTLPHGYGMRY
KGGPPVGPELNRLTSGAHCDPLSRTPYHKYVPVHLRVVDTPVAAPATLEAESA

Sequences:

>Translated_773_residues
MEHAMAVEKTACILCSRNCGLVVDVTDGKFAKIRGDDDHPVSKGYLCQKAARLTYYQHHDDRLTHPLRREPDGSFVRVTW
DEALDDIAQRLVALRERHGGDAFAFVGGGGQGNHVGGAYSRQLLAAMRSRYAYNALGQEKTGDFWLNGRLFGRQDCHTTE
DIEHADYVLVIGANPYQAHGIPNARDTLRDLKKDPARTLVVVDPRRSETAKFADLHLQVRPGADAYLMSAMLAIMLRDGL
FDRAFIAQRCTGFEFVERVLRDVPIAEYARRADVPLEDIERVAHGFATARAACLRIDLGIQHTLHTTLNGYLEKLLFLLT
GHFGKRGGNNLHSFLLPVIGHTDERAIRHGKPLKRTAHHRMFPIAGIYPPNILPDEIERAGEKRVRAAFVDSANPVVTYA
DTNAYERAFGKLELLVVIDVAMTETARLAHYVLPAASQFEKWEATGFNLEFPANAFHLRHPLLPPLGESLPEPEIYTRLL
EKMGELPRRFPLLERIARFEPRASKHLAYLGALGIVLAANKKWQRHAASIVYRTLGRALPGDAAASAPLLPLAMLYAQRH
YAAVRRAGFRGNRATLGTALFRAILERRSGTLISVHEFDEMWRFIRHPDARVHLHIPEMIDELRALATETPPGADYPFVL
MAGERRAYNANQIYRDPTWRKVDPHGSLRIHPDDAAALGVADGGKLVCASATGSIEVVAELDDSVRRGMVTLPHGYGMRY
KGGPPVGPELNRLTSGAHCDPLSRTPYHKYVPVHLRVVDTPVAAPATLEAESA
>Mature_773_residues
MEHAMAVEKTACILCSRNCGLVVDVTDGKFAKIRGDDDHPVSKGYLCQKAARLTYYQHHDDRLTHPLRREPDGSFVRVTW
DEALDDIAQRLVALRERHGGDAFAFVGGGGQGNHVGGAYSRQLLAAMRSRYAYNALGQEKTGDFWLNGRLFGRQDCHTTE
DIEHADYVLVIGANPYQAHGIPNARDTLRDLKKDPARTLVVVDPRRSETAKFADLHLQVRPGADAYLMSAMLAIMLRDGL
FDRAFIAQRCTGFEFVERVLRDVPIAEYARRADVPLEDIERVAHGFATARAACLRIDLGIQHTLHTTLNGYLEKLLFLLT
GHFGKRGGNNLHSFLLPVIGHTDERAIRHGKPLKRTAHHRMFPIAGIYPPNILPDEIERAGEKRVRAAFVDSANPVVTYA
DTNAYERAFGKLELLVVIDVAMTETARLAHYVLPAASQFEKWEATGFNLEFPANAFHLRHPLLPPLGESLPEPEIYTRLL
EKMGELPRRFPLLERIARFEPRASKHLAYLGALGIVLAANKKWQRHAASIVYRTLGRALPGDAAASAPLLPLAMLYAQRH
YAAVRRAGFRGNRATLGTALFRAILERRSGTLISVHEFDEMWRFIRHPDARVHLHIPEMIDELRALATETPPGADYPFVL
MAGERRAYNANQIYRDPTWRKVDPHGSLRIHPDDAAALGVADGGKLVCASATGSIEVVAELDDSVRRGMVTLPHGYGMRY
KGGPPVGPELNRLTSGAHCDPLSRTPYHKYVPVHLRVVDTPVAAPATLEAESA

Specific function: Catalyzes the oxidation of formate [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI3868721, Length=471, Percent_Identity=28.0254777070064, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1787870, Length=486, Percent_Identity=25.5144032921811, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI171474008, Length=361, Percent_Identity=24.9307479224377, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI87081797, Length=508, Percent_Identity=23.4251968503937, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1788534, Length=260, Percent_Identity=25.7692307692308, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI145693196, Length=470, Percent_Identity=26.3829787234043, Blast_Score=84, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006478
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.2.1.2 [H]

Molecular weight: Translated: 85984; Mature: 85984

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHAMAVEKTACILCSRNCGLVVDVTDGKFAKIRGDDDHPVSKGYLCQKAARLTYYQHHD
CCCCHHHHHHEEEEEECCCCEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHEECCC
DRLTHPLRREPDGSFVRVTWDEALDDIAQRLVALRERHGGDAFAFVGGGGQGNHVGGAYS
CHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHH
RQLLAAMRSRYAYNALGQEKTGDFWLNGRLFGRQDCHTTEDIEHADYVLVIGANPYQAHG
HHHHHHHHHHHHHHHCCCCCCCCEEECCEEECCCCCCCCCCCCCCCEEEEECCCCCCCCC
IPNARDTLRDLKKDPARTLVVVDPRRSETAKFADLHLQVRPGADAYLMSAMLAIMLRDGL
CCCHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHCCC
FDRAFIAQRCTGFEFVERVLRDVPIAEYARRADVPLEDIERVAHGFATARAACLRIDLGI
HHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEEECCC
QHTLHTTLNGYLEKLLFLLTGHFGKRGGNNLHSFLLPVIGHTDERAIRHGKPLKRTAHHR
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHCCCCHHHHHHCC
MFPIAGIYPPNILPDEIERAGEKRVRAAFVDSANPVVTYADTNAYERAFGKLELLVVIDV
CCEECCCCCCCCCHHHHHHHHHHHHHHHEECCCCCEEEEECCCHHHHHHCCEEEEEEEEE
AMTETARLAHYVLPAASQFEKWEATGFNLEFPANAFHLRHPLLPPLGESLPEPEIYTRLL
HHHHHHHHHHHHCCCHHHHHHHHCCCCCEECCCCHHHHCCCCCCCCCCCCCCHHHHHHHH
EKMGELPRRFPLLERIARFEPRASKHLAYLGALGIVLAANKKWQRHAASIVYRTLGRALP
HHHHCCHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHCCCC
GDAAASAPLLPLAMLYAQRHYAAVRRAGFRGNRATLGTALFRAILERRSGTLISVHEFDE
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHH
MWRFIRHPDARVHLHIPEMIDELRALATETPPGADYPFVLMAGERRAYNANQIYRDPTWR
HHHHHHCCCCEEEEECHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCC
KVDPHGSLRIHPDDAAALGVADGGKLVCASATGSIEVVAELDDSVRRGMVTLPHGYGMRY
EECCCCCEEECCCCCCEEEECCCCCEEEEECCCCEEEEEECHHHHHCCEEECCCCCCCCC
KGGPPVGPELNRLTSGAHCDPLSRTPYHKYVPVHLRVVDTPVAAPATLEAESA
CCCCCCCCCHHHHCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MEHAMAVEKTACILCSRNCGLVVDVTDGKFAKIRGDDDHPVSKGYLCQKAARLTYYQHHD
CCCCHHHHHHEEEEEECCCCEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHEECCC
DRLTHPLRREPDGSFVRVTWDEALDDIAQRLVALRERHGGDAFAFVGGGGQGNHVGGAYS
CHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHH
RQLLAAMRSRYAYNALGQEKTGDFWLNGRLFGRQDCHTTEDIEHADYVLVIGANPYQAHG
HHHHHHHHHHHHHHHCCCCCCCCEEECCEEECCCCCCCCCCCCCCCEEEEECCCCCCCCC
IPNARDTLRDLKKDPARTLVVVDPRRSETAKFADLHLQVRPGADAYLMSAMLAIMLRDGL
CCCHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHCCC
FDRAFIAQRCTGFEFVERVLRDVPIAEYARRADVPLEDIERVAHGFATARAACLRIDLGI
HHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEEECCC
QHTLHTTLNGYLEKLLFLLTGHFGKRGGNNLHSFLLPVIGHTDERAIRHGKPLKRTAHHR
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHCCCCHHHHHHCC
MFPIAGIYPPNILPDEIERAGEKRVRAAFVDSANPVVTYADTNAYERAFGKLELLVVIDV
CCEECCCCCCCCCHHHHHHHHHHHHHHHEECCCCCEEEEECCCHHHHHHCCEEEEEEEEE
AMTETARLAHYVLPAASQFEKWEATGFNLEFPANAFHLRHPLLPPLGESLPEPEIYTRLL
HHHHHHHHHHHHCCCHHHHHHHHCCCCCEECCCCHHHHCCCCCCCCCCCCCCHHHHHHHH
EKMGELPRRFPLLERIARFEPRASKHLAYLGALGIVLAANKKWQRHAASIVYRTLGRALP
HHHHCCHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHCCCC
GDAAASAPLLPLAMLYAQRHYAAVRRAGFRGNRATLGTALFRAILERRSGTLISVHEFDE
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHH
MWRFIRHPDARVHLHIPEMIDELRALATETPPGADYPFVLMAGERRAYNANQIYRDPTWR
HHHHHHCCCCEEEEECHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCC
KVDPHGSLRIHPDDAAALGVADGGKLVCASATGSIEVVAELDDSVRRGMVTLPHGYGMRY
EECCCCCEEECCCCCCEEEECCCCCEEEEECCCCEEEEEECHHHHHCCEEECCCCCCCCC
KGGPPVGPELNRLTSGAHCDPLSRTPYHKYVPVHLRVVDTPVAAPATLEAESA
CCCCCCCCCHHHHCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]