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The map label for this gene is pyrH [H]

Identifier: 53719766

GI number: 53719766

Start: 2587511

End: 2588224

Strand: Reverse

Name: pyrH [H]

Synonym: BPSL2157

Alternate gene names: 53719766

Gene position: 2588224-2587511 (Counterclockwise)

Preceding gene: 53719767

Following gene: 53719765

Centisome position: 63.52

GC content: 66.95

Gene sequence:

>714_bases
ATGCCCAATGCCTATAAACGCGTCCTCCTCAAACTTTCCGGCGAAGCTCTGATGGGCGACGATGCCTTCGGCATCAATCG
CGCGACGATCGAGCGGATGGTTGCCGACATCGCGGAAGTCGTGCGTCTCGGCACGCAGCTTGCGGTCGTGATCGGCGGGG
GCAACATCTTTCGCGGCGTCGCGGGCGGCGCGGCCGGCATGGACCGCGCGACGGCCGACTACATGGGGATGCTCGCGACG
ATGATGAACGCGCTCGCGCTGCAGGACGCGATGCGCCACGCGGGCATCGAGGCGCGCGTGCAGTCGGCGCTGCGCATGGA
CCAGGTGGTCGAGCCGTACATCCGCCCGCGCGCGATCCGCCAGCTCGAGGAGGGCAAGGTGGTGATCTTCGCGGCGGGCA
CGGGCAACCCGTTCTTCACGACGGACACGGCGGCCGCGCTGCGCGGCTCGGAAGTCGGCGCCGAGGTGGTGCTGAAGGCG
ACGAAGGTCGACGGCGTCTACTCGGCCGATCCGAAGAAGGACCCGTCGGCGACGCGCTATTCGTCGATCAGCTTCGACGA
GGCGATCGGCCGCAACCTGCAGGTGATGGACGCGACGGCGTTCGCGCTCTGCCGCGACCAGAAGCTGCCGATCCGCGTGT
TTTCGATCAACAAGCCGGGTGCGCTCAAACGTATCGTTCAAGGAGAGGACGAGGGCACGCTCGTCCACGTGTAA

Upstream 100 bases:

>100_bases
GACGGGGCTCTCAGCCAGCCCGGCCCGGCGGCGCTTGCCCGAACCAGCATTTCGCCCCTACAGTTCGTGCTTGTCATCCT
CTCGTCGCTCGGAAGTCCCT

Downstream 100 bases:

>100_bases
ACTCTCGCCGATGCGGGAGGCCGCGGCGCCGCGCGCCGCCTTTGGCCATTGCCCGCATCGTTTTGAAGTTCGGAAGGTTC
GGAGGTTGAAATGAGTGTCG

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MPNAYKRVLLKLSGEALMGDDAFGINRATIERMVADIAEVVRLGTQLAVVIGGGNIFRGVAGGAAGMDRATADYMGMLAT
MMNALALQDAMRHAGIEARVQSALRMDQVVEPYIRPRAIRQLEEGKVVIFAAGTGNPFFTTDTAAALRGSEVGAEVVLKA
TKVDGVYSADPKKDPSATRYSSISFDEAIGRNLQVMDATAFALCRDQKLPIRVFSINKPGALKRIVQGEDEGTLVHV

Sequences:

>Translated_237_residues
MPNAYKRVLLKLSGEALMGDDAFGINRATIERMVADIAEVVRLGTQLAVVIGGGNIFRGVAGGAAGMDRATADYMGMLAT
MMNALALQDAMRHAGIEARVQSALRMDQVVEPYIRPRAIRQLEEGKVVIFAAGTGNPFFTTDTAAALRGSEVGAEVVLKA
TKVDGVYSADPKKDPSATRYSSISFDEAIGRNLQVMDATAFALCRDQKLPIRVFSINKPGALKRIVQGEDEGTLVHV
>Mature_236_residues
PNAYKRVLLKLSGEALMGDDAFGINRATIERMVADIAEVVRLGTQLAVVIGGGNIFRGVAGGAAGMDRATADYMGMLATM
MNALALQDAMRHAGIEARVQSALRMDQVVEPYIRPRAIRQLEEGKVVIFAAGTGNPFFTTDTAAALRGSEVGAEVVLKAT
KVDGVYSADPKKDPSATRYSSISFDEAIGRNLQVMDATAFALCRDQKLPIRVFSINKPGALKRIVQGEDEGTLVHV

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=231, Percent_Identity=57.5757575757576, Blast_Score=280, Evalue=6e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 25330; Mature: 25198

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNAYKRVLLKLSGEALMGDDAFGINRATIERMVADIAEVVRLGTQLAVVIGGGNIFRGV
CCCHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEHHC
AGGAAGMDRATADYMGMLATMMNALALQDAMRHAGIEARVQSALRMDQVVEPYIRPRAIR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHH
QLEEGKVVIFAAGTGNPFFTTDTAAALRGSEVGAEVVLKATKVDGVYSADPKKDPSATRY
HHCCCCEEEEEECCCCCCEECCHHHHHCCCCCCHHHEEEEECCCCEECCCCCCCCCCCCC
SSISFDEAIGRNLQVMDATAFALCRDQKLPIRVFSINKPGALKRIVQGEDEGTLVHV
CCCCHHHHHCCCEEEEHHHHHHHHCCCCCCEEEEEECCCHHHHHHHCCCCCCCEEEC
>Mature Secondary Structure 
PNAYKRVLLKLSGEALMGDDAFGINRATIERMVADIAEVVRLGTQLAVVIGGGNIFRGV
CCHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEHHC
AGGAAGMDRATADYMGMLATMMNALALQDAMRHAGIEARVQSALRMDQVVEPYIRPRAIR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHH
QLEEGKVVIFAAGTGNPFFTTDTAAALRGSEVGAEVVLKATKVDGVYSADPKKDPSATRY
HHCCCCEEEEEECCCCCCEECCHHHHHCCCCCCHHHEEEEECCCCEECCCCCCCCCCCCC
SSISFDEAIGRNLQVMDATAFALCRDQKLPIRVFSINKPGALKRIVQGEDEGTLVHV
CCCCHHHHHCCCEEEEHHHHHHHHCCCCCCEEEEEECCCHHHHHHHCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA