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The map label for this gene is scoA [H]

Identifier: 53719567

GI number: 53719567

Start: 2326613

End: 2327317

Strand: Reverse

Name: scoA [H]

Synonym: BPSL1955

Alternate gene names: 53719567

Gene position: 2327317-2326613 (Counterclockwise)

Preceding gene: 53719571

Following gene: 53719566

Centisome position: 57.12

GC content: 64.96

Gene sequence:

>705_bases
ATGAACAAAGTCTACCCAAGCGCGGCTGCCGCGCTCGAGGGCGTCGTCCATGACGGGCAGACCTTCGCGGTCGGCGGCTT
CGGCCTGTGCGGCATTCCGGAAGCGCTCATCGCCGCGCTGCGCGATTCGGCGGTGAAGGGCATCACCTGCATCAGCAACA
ACGCGGGCGTTGACGGCTTCGGCCTTGGCCTGCTGCTCGAAACCCGGCAAATCAAGAAGATGATCTCGTCGTACGTCGGC
GAGAACAAGGAGTTCGAACGCCAGTATCTGTCGGGCGAACTCGAGCTCGAGTTCACGCCGCAGGGCACGCTCGCGGAGAA
GCTGCGCGCGGGCGGCGCGGGCATCCCGGCGTTCTTCACGCAGACGGGCTACGGCACCGTGATCGCCGAAGGCAAGGAGA
CGCGCGAGTTCGACGGCAAGCATTACGTGCTCGAGCCGTCGCTCACGGCGGACGTCGCGCTCGTGAAGGCTTGGAAAGCC
GACAAGTCGGGCAACCTGGTTTACCGGCGCACCGCGCGCAACTTCAATCCGATGTGCGCGATGGCGGGCCGGATCACGAT
CGCCGAGGTCGAGGAGATCGTCGAGAACGGCGAGCTCGATCCGGATGCGATCCACACGCCCGGCATTTTCGTGCAGCGGC
TCGTGCTCAACGCGACGCCGGAAAAACGCATCGAACAACGCGTCGTGCGCGCGAAAGGAGACTGA

Upstream 100 bases:

>100_bases
GGCAGTATTCGCCGCGCGTGCTTAGAATGACGCGACAGGTCCGTCGCGCGCGAGCCGCGCGGGCCGTCGAGCTGGTTTCC
ATAGAGGAAGGGACATACAG

Downstream 100 bases:

>100_bases
GATGGCTTGGAATCGTGACCAGATGGCCGCGCGCGCGGCGAAGGAATTGCAGGACGGCTTCTACGTGAACCTCGGCATCG
GGCTGCCGACGCTCGTGGCG

Product: succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MNKVYPSAAAALEGVVHDGQTFAVGGFGLCGIPEALIAALRDSAVKGITCISNNAGVDGFGLGLLLETRQIKKMISSYVG
ENKEFERQYLSGELELEFTPQGTLAEKLRAGGAGIPAFFTQTGYGTVIAEGKETREFDGKHYVLEPSLTADVALVKAWKA
DKSGNLVYRRTARNFNPMCAMAGRITIAEVEEIVENGELDPDAIHTPGIFVQRLVLNATPEKRIEQRVVRAKGD

Sequences:

>Translated_234_residues
MNKVYPSAAAALEGVVHDGQTFAVGGFGLCGIPEALIAALRDSAVKGITCISNNAGVDGFGLGLLLETRQIKKMISSYVG
ENKEFERQYLSGELELEFTPQGTLAEKLRAGGAGIPAFFTQTGYGTVIAEGKETREFDGKHYVLEPSLTADVALVKAWKA
DKSGNLVYRRTARNFNPMCAMAGRITIAEVEEIVENGELDPDAIHTPGIFVQRLVLNATPEKRIEQRVVRAKGD
>Mature_234_residues
MNKVYPSAAAALEGVVHDGQTFAVGGFGLCGIPEALIAALRDSAVKGITCISNNAGVDGFGLGLLLETRQIKKMISSYVG
ENKEFERQYLSGELELEFTPQGTLAEKLRAGGAGIPAFFTQTGYGTVIAEGKETREFDGKHYVLEPSLTADVALVKAWKA
DKSGNLVYRRTARNFNPMCAMAGRITIAEVEEIVENGELDPDAIHTPGIFVQRLVLNATPEKRIEQRVVRAKGD

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=238, Percent_Identity=58.8235294117647, Blast_Score=287, Evalue=5e-78,
Organism=Homo sapiens, GI11545841, Length=238, Percent_Identity=53.781512605042, Blast_Score=241, Evalue=3e-64,
Organism=Escherichia coli, GI1788551, Length=204, Percent_Identity=45.0980392156863, Blast_Score=190, Evalue=8e-50,
Organism=Caenorhabditis elegans, GI17531517, Length=252, Percent_Identity=55.952380952381, Blast_Score=268, Evalue=1e-72,
Organism=Drosophila melanogaster, GI21358325, Length=250, Percent_Identity=53.2, Blast_Score=250, Evalue=5e-67,
Organism=Drosophila melanogaster, GI24655794, Length=250, Percent_Identity=53.2, Blast_Score=250, Evalue=5e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 25218; Mature: 25218

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKVYPSAAAALEGVVHDGQTFAVGGFGLCGIPEALIAALRDSAVKGITCISNNAGVDGF
CCCCCCHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCCCC
GLGLLLETRQIKKMISSYVGENKEFERQYLSGELELEFTPQGTLAEKLRAGGAGIPAFFT
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCCCCHHHC
QTGYGTVIAEGKETREFDGKHYVLEPSLTADVALVKAWKADKSGNLVYRRTARNFNPMCA
CCCCEEEEECCCCCHHCCCCEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHH
MAGRITIAEVEEIVENGELDPDAIHTPGIFVQRLVLNATPEKRIEQRVVRAKGD
HCCCEEHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MNKVYPSAAAALEGVVHDGQTFAVGGFGLCGIPEALIAALRDSAVKGITCISNNAGVDGF
CCCCCCHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCCCC
GLGLLLETRQIKKMISSYVGENKEFERQYLSGELELEFTPQGTLAEKLRAGGAGIPAFFT
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCCCCHHHC
QTGYGTVIAEGKETREFDGKHYVLEPSLTADVALVKAWKADKSGNLVYRRTARNFNPMCA
CCCCEEEEECCCCCHHCCCCEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHH
MAGRITIAEVEEIVENGELDPDAIHTPGIFVQRLVLNATPEKRIEQRVVRAKGD
HCCCEEHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9385134; 11589581 [H]