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The map label for this gene is cysW [H]

Identifier: 53719450

GI number: 53719450

Start: 2190976

End: 2191854

Strand: Reverse

Name: cysW [H]

Synonym: BPSL1837

Alternate gene names: 53719450

Gene position: 2191854-2190976 (Counterclockwise)

Preceding gene: 53719451

Following gene: 53719449

Centisome position: 53.79

GC content: 68.71

Gene sequence:

>879_bases
GTGAGCGAGCCGCGCGCGGTGCGCTGGCTGCTCACGGGCGCGGCGCTCGCGTTCCTCGCGCTCTTTCTCGTCGTGCCGCT
TGCCGCGGTGTTCTTCGAGGCGCTGCGCAAGGGCGTCGATTTCTATCTCGAATCACTCGCCGATCCGGACGCGTGGTCGG
CGATCAAGCTCACGCTCGTCGTCGCCGCGATCGCCGTGCCGCTCAATCTCGTATTCGGCGTGTGCGCGTCGTGGGCGATC
GCGAAGTTCGAGTTCAAGGGCAAGGCGGTGCTGACGACGCTCATCGATCTGCCGTTCTCGGTGTCGCCCGTGATCTCGGG
CCTCGTCTACGTGCTGCTGTTCGGCGCGCAGGGCTGGCTCGGCCCGTGGCTGCAGGCGCATGACGTGCAGATCATCTTCG
CCGTGCCGGGCATCGTGCTCGCGACGATCTTCGTCACGTTCCCGTTCGTCGCGCGCGAGCTGATTCCGCTGATGCAGGCG
CAGGGCGCCGACGAGGAGGAGGCCGCGCGCGTGCTCGGCGCATCCGGCTGGCAGATCTTCCGGCGCGTCACGCTGCCGAA
CGTGAAGTGGGGCCTGCTGTACGGCGTGATTCTCTGCAACGCGCGCGCGATGGGCGAGTTCGGCGCGGTGTCGGTGGTGT
CGGGCCATATCCGCGGGCAGACCGACACGATGCCGCTGCACGTCGAGATTCTCTACAACGAGTACAACTTCGCGGCCGCG
TTCGCGGTGGCGTCGGTACTCGCGCTGCTCGCGCTCGTCACGCTCGCGCTCAAGCTGTTCGCCGAGCGGCGGCTGTCCGC
CGAACTCGCGCACGGGCGCGACGACGCGAGCGCCGCCGCCGCGCACCCGGGCGCCGCCGTCACTTCGTCGATTTCGTAA

Upstream 100 bases:

>100_bases
GGAATTCGGCGCTCGATTCGGCCTTGAATCCGGCCTTGAATCCGGCGATGACGCGCGCCGCGCCGCGCGCGCCCCGGCGC
GAGCGCGCCGGCTCGACCCC

Downstream 100 bases:

>100_bases
AGAGGCAAACCAGATGGGCATCACCGTTCGTAATCTGCACAAACGCTTCGGCGAGTTCGCCGCGCTCGACGACGTCTCGC
TCGATTTCCCCGCGGGTGAG

Product: sulfate transport system permease

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MSEPRAVRWLLTGAALAFLALFLVVPLAAVFFEALRKGVDFYLESLADPDAWSAIKLTLVVAAIAVPLNLVFGVCASWAI
AKFEFKGKAVLTTLIDLPFSVSPVISGLVYVLLFGAQGWLGPWLQAHDVQIIFAVPGIVLATIFVTFPFVARELIPLMQA
QGADEEEAARVLGASGWQIFRRVTLPNVKWGLLYGVILCNARAMGEFGAVSVVSGHIRGQTDTMPLHVEILYNEYNFAAA
FAVASVLALLALVTLALKLFAERRLSAELAHGRDDASAAAAHPGAAVTSSIS

Sequences:

>Translated_292_residues
MSEPRAVRWLLTGAALAFLALFLVVPLAAVFFEALRKGVDFYLESLADPDAWSAIKLTLVVAAIAVPLNLVFGVCASWAI
AKFEFKGKAVLTTLIDLPFSVSPVISGLVYVLLFGAQGWLGPWLQAHDVQIIFAVPGIVLATIFVTFPFVARELIPLMQA
QGADEEEAARVLGASGWQIFRRVTLPNVKWGLLYGVILCNARAMGEFGAVSVVSGHIRGQTDTMPLHVEILYNEYNFAAA
FAVASVLALLALVTLALKLFAERRLSAELAHGRDDASAAAAHPGAAVTSSIS
>Mature_291_residues
SEPRAVRWLLTGAALAFLALFLVVPLAAVFFEALRKGVDFYLESLADPDAWSAIKLTLVVAAIAVPLNLVFGVCASWAIA
KFEFKGKAVLTTLIDLPFSVSPVISGLVYVLLFGAQGWLGPWLQAHDVQIIFAVPGIVLATIFVTFPFVARELIPLMQAQ
GADEEEAARVLGASGWQIFRRVTLPNVKWGLLYGVILCNARAMGEFGAVSVVSGHIRGQTDTMPLHVEILYNEYNFAAAF
AVASVLALLALVTLALKLFAERRLSAELAHGRDDASAAAAHPGAAVTSSIS

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4208

COG function: function code P; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082099, Length=268, Percent_Identity=52.6119402985075, Blast_Score=298, Evalue=3e-82,
Organism=Escherichia coli, GI1788764, Length=206, Percent_Identity=36.8932038834951, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1786980, Length=181, Percent_Identity=34.8066298342541, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787369, Length=175, Percent_Identity=28, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011866
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31205; Mature: 31074

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPRAVRWLLTGAALAFLALFLVVPLAAVFFEALRKGVDFYLESLADPDAWSAIKLTLV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
VAAIAVPLNLVFGVCASWAIAKFEFKGKAVLTTLIDLPFSVSPVISGLVYVLLFGAQGWL
HHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCC
GPWLQAHDVQIIFAVPGIVLATIFVTFPFVARELIPLMQAQGADEEEAARVLGASGWQIF
CCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHH
RRVTLPNVKWGLLYGVILCNARAMGEFGAVSVVSGHIRGQTDTMPLHVEILYNEYNFAAA
HHHCCCCCHHHHHHHHHHHCCHHCCCCCCHHHHCCCCCCCCCCCEEEEEEEECCCHHHHH
FAVASVLALLALVTLALKLFAERRLSAELAHGRDDASAAAAHPGAAVTSSIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCHHCCCCC
>Mature Secondary Structure 
SEPRAVRWLLTGAALAFLALFLVVPLAAVFFEALRKGVDFYLESLADPDAWSAIKLTLV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
VAAIAVPLNLVFGVCASWAIAKFEFKGKAVLTTLIDLPFSVSPVISGLVYVLLFGAQGWL
HHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCC
GPWLQAHDVQIIFAVPGIVLATIFVTFPFVARELIPLMQAQGADEEEAARVLGASGWQIF
CCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHH
RRVTLPNVKWGLLYGVILCNARAMGEFGAVSVVSGHIRGQTDTMPLHVEILYNEYNFAAA
HHHCCCCCHHHHHHHHHHHCCHHCCCCCCHHHHCCCCCCCCCCCEEEEEEEECCCHHHHH
FAVASVLALLALVTLALKLFAERRLSAELAHGRDDASAAAAHPGAAVTSSIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]