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The map label for this gene is rbsK [H]

Identifier: 53719443

GI number: 53719443

Start: 2182764

End: 2183738

Strand: Reverse

Name: rbsK [H]

Synonym: BPSL1830

Alternate gene names: 53719443

Gene position: 2183738-2182764 (Counterclockwise)

Preceding gene: 53719444

Following gene: 53719442

Centisome position: 53.59

GC content: 77.74

Gene sequence:

>975_bases
ATGACGGCCGCCGTCGAACGCGCGGCCGGCGGGGCCTCGCCCGCGCGCGCCGGCAGGGTGATGGTGGTCGGCAGCCTGAA
CATGGACCTCGTCGTGCGCTCGGCGCGGCTGCCGCGGCCGGGCGAGACGCTCGCCGGCCGCTCGTTCGCGCAGGCGGCGG
GCGGCAAGGGCGGCAACCAGGCGGTCGCGGCCGCGCGGCTCGGCGCGCAGGTGGCGATGCTCGGCCGCGTCGGCGCGGAC
GCGCACGGCGCCGCGCTGCGCGCGGGGCTCGTCGCCGAGGGGATCGATTGCGTCGCGCTGTCGGTCAGCGCGACGGCGAC
GACGGGCGTCGCGCTCATCGTCGTCGACGATGCGAGCCAGAACGCGATCGTGATCGTCGCGGGCAGCAACGGCGAGGTGA
CCCCCGAATCGATCGCCGGGCACGAGGCGGCGATCGCCGCGGCCGACGTGCTGATCTGCCAGCTCGAGACGCCCGCCGCC
GCGGTTCGCGCGGCGCTGGCCGCCGGCCGCCGGCTCGGCAAGACCGTCGTGCTGAATCCGGCGCCCGCTGCCGGCCCGCT
GCCCGCCGACTGGCTGCCGCTCGTCGATTACCTGATCCCGAACGAAATCGAGGCCGCCGCGCTGACCGGCTTGCCGGTGC
GCGACCCGGCGAGCGCCGAGACCGCCGCGCGCGCGCTTGCGGCGGCTGGCGCGCGCAACGTGATCGTCACGCTGGGCGGC
CAGGGCGTTCTCGCGCTGACGGCGGACGGCGACGCGCGCCACTACCCGGCGCCGCGCGTCGCGCCCGTCGACACGACGGC
CGCGGGGGACACGTTCATCGGAGGTTTCGCCGCGCGGCTCGCCGCGCGCGACGCGCCGCACGACGCGATCCGGTTCGCGC
AGCGCGCGGCTGCGTTGTCGGTCACGCGCGCGGGCGCGCAGCCGTCGATTCCGACGCTCGCCGAGCTCGACGCGTTCGCG
CCGGGGCCGGCGTGA

Upstream 100 bases:

>100_bases
CGTCGGGCGCGCCGCAGCGCCGCCGCGTCGTGTCGCCGCGCCTCGTGCTGCGCGAATCGACGACTGTCTACGTGGAGCCG
GCCGACGCCGGGTATCGCGG

Downstream 100 bases:

>100_bases
CACAACGCCGCGGTCGCGCCGGGCATGTAAGCCAAGAGAAAGAAAATATCGAGCCGGCGGCCGCGCCAAATAAGTTTTTC
TTCGCACGGGCGGCTGCCCA

Product: putative ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MTAAVERAAGGASPARAGRVMVVGSLNMDLVVRSARLPRPGETLAGRSFAQAAGGKGGNQAVAAARLGAQVAMLGRVGAD
AHGAALRAGLVAEGIDCVALSVSATATTGVALIVVDDASQNAIVIVAGSNGEVTPESIAGHEAAIAAADVLICQLETPAA
AVRAALAAGRRLGKTVVLNPAPAAGPLPADWLPLVDYLIPNEIEAAALTGLPVRDPASAETAARALAAAGARNVIVTLGG
QGVLALTADGDARHYPAPRVAPVDTTAAGDTFIGGFAARLAARDAPHDAIRFAQRAAALSVTRAGAQPSIPTLAELDAFA
PGPA

Sequences:

>Translated_324_residues
MTAAVERAAGGASPARAGRVMVVGSLNMDLVVRSARLPRPGETLAGRSFAQAAGGKGGNQAVAAARLGAQVAMLGRVGAD
AHGAALRAGLVAEGIDCVALSVSATATTGVALIVVDDASQNAIVIVAGSNGEVTPESIAGHEAAIAAADVLICQLETPAA
AVRAALAAGRRLGKTVVLNPAPAAGPLPADWLPLVDYLIPNEIEAAALTGLPVRDPASAETAARALAAAGARNVIVTLGG
QGVLALTADGDARHYPAPRVAPVDTTAAGDTFIGGFAARLAARDAPHDAIRFAQRAAALSVTRAGAQPSIPTLAELDAFA
PGPA
>Mature_323_residues
TAAVERAAGGASPARAGRVMVVGSLNMDLVVRSARLPRPGETLAGRSFAQAAGGKGGNQAVAAARLGAQVAMLGRVGADA
HGAALRAGLVAEGIDCVALSVSATATTGVALIVVDDASQNAIVIVAGSNGEVTPESIAGHEAAIAAADVLICQLETPAAA
VRAALAAGRRLGKTVVLNPAPAAGPLPADWLPLVDYLIPNEIEAAALTGLPVRDPASAETAARALAAAGARNVIVTLGGQ
GVLALTADGDARHYPAPRVAPVDTTAAGDTFIGGFAARLAARDAPHDAIRFAQRAAALSVTRAGAQPSIPTLAELDAFAP
GPA

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=297, Percent_Identity=40.4040404040404, Blast_Score=186, Evalue=2e-47,
Organism=Escherichia coli, GI1790193, Length=304, Percent_Identity=43.75, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI87082343, Length=304, Percent_Identity=32.2368421052632, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1788484, Length=315, Percent_Identity=27.6190476190476, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788491, Length=298, Percent_Identity=24.8322147651007, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17532905, Length=305, Percent_Identity=40.655737704918, Blast_Score=199, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6319884, Length=335, Percent_Identity=31.3432835820896, Blast_Score=137, Evalue=2e-33,
Organism=Drosophila melanogaster, GI20128807, Length=301, Percent_Identity=40.1993355481728, Blast_Score=174, Evalue=8e-44,
Organism=Drosophila melanogaster, GI24583886, Length=299, Percent_Identity=33.1103678929766, Blast_Score=139, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 31850; Mature: 31718

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAAVERAAGGASPARAGRVMVVGSLNMDLVVRSARLPRPGETLAGRSFAQAAGGKGGNQ
CCCCHHHHCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCHHCCCHHHHHHCCCCCCH
AVAAARLGAQVAMLGRVGADAHGAALRAGLVAEGIDCVALSVSATATTGVALIVVDDASQ
HHHHHHHCHHEEEHHHCCCCCCCHHHHHHHHHCCCEEEEEEEECCCCCCEEEEEEECCCC
NAIVIVAGSNGEVTPESIAGHEAAIAAADVLICQLETPAAAVRAALAAGRRLGKTVVLNP
CEEEEEECCCCCCCHHHHCCCHHHHHEEEEEEEEECCCHHHHHHHHHHHHHCCCEEEECC
APAAGPLPADWLPLVDYLIPNEIEAAALTGLPVRDPASAETAARALAAAGARNVIVTLGG
CCCCCCCCCCHHHHHHHHCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECC
QGVLALTADGDARHYPAPRVAPVDTTAAGDTFIGGFAARLAARDAPHDAIRFAQRAAALS
CEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VTRAGAQPSIPTLAELDAFAPGPA
HEECCCCCCCCCHHHHHCCCCCCC
>Mature Secondary Structure 
TAAVERAAGGASPARAGRVMVVGSLNMDLVVRSARLPRPGETLAGRSFAQAAGGKGGNQ
CCCHHHHCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCHHCCCHHHHHHCCCCCCH
AVAAARLGAQVAMLGRVGADAHGAALRAGLVAEGIDCVALSVSATATTGVALIVVDDASQ
HHHHHHHCHHEEEHHHCCCCCCCHHHHHHHHHCCCEEEEEEEECCCCCCEEEEEEECCCC
NAIVIVAGSNGEVTPESIAGHEAAIAAADVLICQLETPAAAVRAALAAGRRLGKTVVLNP
CEEEEEECCCCCCCHHHHCCCHHHHHEEEEEEEEECCCHHHHHHHHHHHHHCCCEEEECC
APAAGPLPADWLPLVDYLIPNEIEAAALTGLPVRDPASAETAARALAAAGARNVIVTLGG
CCCCCCCCCCHHHHHHHHCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECC
QGVLALTADGDARHYPAPRVAPVDTTAAGDTFIGGFAARLAARDAPHDAIRFAQRAAALS
CEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VTRAGAQPSIPTLAELDAFAPGPA
HEECCCCCCCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]