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The map label for this gene is cobM [H]

Identifier: 53719369

GI number: 53719369

Start: 2068491

End: 2069216

Strand: Reverse

Name: cobM [H]

Synonym: BPSL1755

Alternate gene names: 53719369

Gene position: 2069216-2068491 (Counterclockwise)

Preceding gene: 53719370

Following gene: 53719366

Centisome position: 50.78

GC content: 71.21

Gene sequence:

>726_bases
ATGACGGTGTACTTCATCGGCGCGGGTCCGGGCGACCCCGAGCTGATCACGGTGAAGGGCCAGCGCCTCGTGCGCCGTTG
CCCGGTGATCCTGTACGCGGGCTCGCTCGTGCCGGCCGCGGTGCTCGACGGCCATCGCGCCGAGCTCGTCGTGAACACGG
CGGAGCTCGATCTCGACGAAATCGTCGCGCTGCTCGCGCGCGCGCACGGCAAGGGGCAGGACGTCGCGCGCGTGCATTCC
GGCGATCCGTCGCTCTACGGCGCGATCGGCGAGCAGATCCGCCGGCTCGCCGCGCTCGGGATTCCTTACGAGATCGTGCC
CGGCGTGACCGCGACGGCCGCGTGCGCAGCGGCGCTCGGCGTCGAGCTGACGCTGCCGGGCGTCGCGCAGACCGTGATCC
TCACGCGCTACGCGGGCAAGACGACGATGCCCGCCGGCGAATCGCTCGCGAGCCTCGCCGCGCACCGCGCGACGCTCGCG
ATCCATCTCGGCGTGCGGCATCTCGCGCGGATCGTCGCCGACGTGCTGCCGCACTACGGCGCGGATTGCCCGATCGCCGT
GATCTATCGCGCGAGCTGGCCCGACGAGGCGCGCGTGACGGGCACCCTCGCCGACATCGTCGACAAGGTTTCAGGCAGGT
CGATCGAGCGCACCGCGCTGATCCTGATCGGGCGGGTGCTCAGTGCCGAAGGCTTCGACGAGTCGACGCTCTATGCGAAG
GCGTGA

Upstream 100 bases:

>100_bases
GCGGCTTGCGACGCAGGCGTGAGCCGAGGCTCGCGGCTCGCAGCGCTCGGCGCGCGACGCATCGTCCTCGAATCATCGAA
TGAATGACGGAGTGTGTTGA

Downstream 100 bases:

>100_bases
CGGCATCAAGATGCGAACGCGCGAAGGCGTGCGCAAGCGAGGACTTGACGAGCCGCTCGCGCATGCGCGAGCGGCGTGTC
AGCGCGGCTTCGCCGCCGGC

Product: precorrin-4 C11-methyltransferase

Products: NA

Alternate protein names: Precorrin-3 methylase [H]

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MTVYFIGAGPGDPELITVKGQRLVRRCPVILYAGSLVPAAVLDGHRAELVVNTAELDLDEIVALLARAHGKGQDVARVHS
GDPSLYGAIGEQIRRLAALGIPYEIVPGVTATAACAAALGVELTLPGVAQTVILTRYAGKTTMPAGESLASLAAHRATLA
IHLGVRHLARIVADVLPHYGADCPIAVIYRASWPDEARVTGTLADIVDKVSGRSIERTALILIGRVLSAEGFDESTLYAK
A

Sequences:

>Translated_241_residues
MTVYFIGAGPGDPELITVKGQRLVRRCPVILYAGSLVPAAVLDGHRAELVVNTAELDLDEIVALLARAHGKGQDVARVHS
GDPSLYGAIGEQIRRLAALGIPYEIVPGVTATAACAAALGVELTLPGVAQTVILTRYAGKTTMPAGESLASLAAHRATLA
IHLGVRHLARIVADVLPHYGADCPIAVIYRASWPDEARVTGTLADIVDKVSGRSIERTALILIGRVLSAEGFDESTLYAK
A
>Mature_240_residues
TVYFIGAGPGDPELITVKGQRLVRRCPVILYAGSLVPAAVLDGHRAELVVNTAELDLDEIVALLARAHGKGQDVARVHSG
DPSLYGAIGEQIRRLAALGIPYEIVPGVTATAACAAALGVELTLPGVAQTVILTRYAGKTTMPAGESLASLAAHRATLAI
HLGVRHLARIVADVLPHYGADCPIAVIYRASWPDEARVTGTLADIVDKVSGRSIERTALILIGRVLSAEGFDESTLYAKA

Specific function: Catalyzes the methylation of C-11 in precorrin-4 to form precorrin-5 [H]

COG id: COG2875

COG function: function code H; Precorrin-4 methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789768, Length=238, Percent_Identity=31.5126050420168, Blast_Score=100, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6322922, Length=256, Percent_Identity=26.171875, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR006362
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.133 [H]

Molecular weight: Translated: 25227; Mature: 25095

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS00839 SUMT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVYFIGAGPGDPELITVKGQRLVRRCPVILYAGSLVPAAVLDGHRAELVVNTAELDLDE
CEEEEEECCCCCCCEEEECHHHHHHHCCEEEEECCCHHHHHHCCCCEEEEEEHHHCCHHH
IVALLARAHGKGQDVARVHSGDPSLYGAIGEQIRRLAALGIPYEIVPGVTATAACAAALG
HHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHC
VELTLPGVAQTVILTRYAGKTTMPAGESLASLAAHRATLAIHLGVRHLARIVADVLPHYG
CEEECCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHCC
ADCPIAVIYRASWPDEARVTGTLADIVDKVSGRSIERTALILIGRVLSAEGFDESTLYAK
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEEEC
A
C
>Mature Secondary Structure 
TVYFIGAGPGDPELITVKGQRLVRRCPVILYAGSLVPAAVLDGHRAELVVNTAELDLDE
EEEEEECCCCCCCEEEECHHHHHHHCCEEEEECCCHHHHHHCCCCEEEEEEHHHCCHHH
IVALLARAHGKGQDVARVHSGDPSLYGAIGEQIRRLAALGIPYEIVPGVTATAACAAALG
HHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHC
VELTLPGVAQTVILTRYAGKTTMPAGESLASLAAHRATLAIHLGVRHLARIVADVLPHYG
CEEECCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHCC
ADCPIAVIYRASWPDEARVTGTLADIVDKVSGRSIERTALILIGRVLSAEGFDESTLYAK
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEEEC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]