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The map label for this gene is argG

Identifier: 53719335

GI number: 53719335

Start: 2027369

End: 2028583

Strand: Reverse

Name: argG

Synonym: BPSL1721

Alternate gene names: 53719335

Gene position: 2028583-2027369 (Counterclockwise)

Preceding gene: 53719336

Following gene: 53719334

Centisome position: 49.79

GC content: 66.17

Gene sequence:

>1215_bases
ATGAAACCCAAACACATTCTCCTCGCTTATTCCGGCGGCCTCGACACGTCCACCGCGCTGCACTTCCTGAAGCGGCATTT
CGATTGCCGCGTCACCGCCTATTGCGCGAACCTCGGGCAGAAGGAGGATTGGGAGCGGATGAAACGCCGCGCGGCGATCG
CCGGCGCGGACGAGCTGGTCATCGAGGATCTGCGCGAGACGTTCATCGGCGATTTCGTGTTTCCCGCACTGAAGGCGAAC
GCGTCGTACGAGCGGGACTATCTGCTCGGCACGCCGCTCGCCCGCCCGGCGATCGTCAAGGGGCTCATCGAGTACGCGCG
CAAGCACGACGTCGATTGCCTGTCGCACGGCTGCACGCAGAAGGGCAACGATCAGGTGCGCTTCGAGATGGCCGCGAAGA
TCCTCGCGCCCGATCTGCCGACGGTCGCGCCGTGGCGCATCTGGTCGCTGCAGTCGCGCGAGGATCTGTTCGCGTATTGT
CAGCAGCACGGCATTCCGGTCGAAAGCCGTCCGGACAATCTGTTGAGCCACGACGAGAATCTCGTGCACATCACGACGGA
GGGCGACTATCTGGAGAGCGTCGCGAACGCGTTCGACTGGCGCGACGCGAACTGGATCACGCCGCCCACGCAAGCGCCGG
ATGCGATCGAGACGATCACGCTCGGGTTCCGCCGGGGCGTGCCCGTCAGCGTCGACGGCGCGGCGCTCGGGCCGGTCGAG
CTGGTCGAGCGGCTCAACGAAGCGGGCGCCCGCAACGGCGTCGGCTTCCAGGACATCATCGAGAACCGCATCAACGGCCT
GAAGGTGCGCGGCGTGTTCGAGAACCCCGCGCTGACGATCCTGCACGCCGCGCATCGCAAGCTCGAGAAGATCACGCTCG
GCCGCGACGTCGAGCGCCTGCGCAACCTCGTGTCGGACGACTACGGCGACATCGTCTACCGCGGCCTGTGGTTCAGCGAC
GAGCGGCTCTGCCTGCAGGCGCTCATCGACGAATCGCAGAAGTACGTGAGCGGCGACGTGAAGGTTCAGCTCTACAAGGG
TTCGTGCACGCCGTGCGCCGTCGAATCGGAGCAGTCGCTTTATTCGCGCGAGCTCGTGACGCTGCACGCGGGCCGCGCGA
TCAGCGGCGAGGACGCGACGGGTTTCCTGAACACGCTCGGCCTGCGTATCGGCATCGAAGCCGCGCGCGCCGGCAACACG
GGAGCCGGCGCATGA

Upstream 100 bases:

>100_bases
GAACTGGCCGACAACGTCAACCAGATTCGCGGCAAGCGCGACAACTACCTCGTCGGCTAGTCGGCGAGGCGGCGAACCCA
TCCATCACGGAAGATCGGAC

Downstream 100 bases:

>100_bases
GCAATCCGATGGCGAATCCGTGGGCCGGACGCTTCAGCCAGACGATGACCGACAGCCTGGTGGCGTTCAACACGAGCCTG
CCGCTCGAGACGCGGCTCTT

Product: putative argininosuccinate synthase

Products: NA

Alternate protein names: Citrulline--aspartate ligase

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MKPKHILLAYSGGLDTSTALHFLKRHFDCRVTAYCANLGQKEDWERMKRRAAIAGADELVIEDLRETFIGDFVFPALKAN
ASYERDYLLGTPLARPAIVKGLIEYARKHDVDCLSHGCTQKGNDQVRFEMAAKILAPDLPTVAPWRIWSLQSREDLFAYC
QQHGIPVESRPDNLLSHDENLVHITTEGDYLESVANAFDWRDANWITPPTQAPDAIETITLGFRRGVPVSVDGAALGPVE
LVERLNEAGARNGVGFQDIIENRINGLKVRGVFENPALTILHAAHRKLEKITLGRDVERLRNLVSDDYGDIVYRGLWFSD
ERLCLQALIDESQKYVSGDVKVQLYKGSCTPCAVESEQSLYSRELVTLHAGRAISGEDATGFLNTLGLRIGIEAARAGNT
GAGA

Sequences:

>Translated_404_residues
MKPKHILLAYSGGLDTSTALHFLKRHFDCRVTAYCANLGQKEDWERMKRRAAIAGADELVIEDLRETFIGDFVFPALKAN
ASYERDYLLGTPLARPAIVKGLIEYARKHDVDCLSHGCTQKGNDQVRFEMAAKILAPDLPTVAPWRIWSLQSREDLFAYC
QQHGIPVESRPDNLLSHDENLVHITTEGDYLESVANAFDWRDANWITPPTQAPDAIETITLGFRRGVPVSVDGAALGPVE
LVERLNEAGARNGVGFQDIIENRINGLKVRGVFENPALTILHAAHRKLEKITLGRDVERLRNLVSDDYGDIVYRGLWFSD
ERLCLQALIDESQKYVSGDVKVQLYKGSCTPCAVESEQSLYSRELVTLHAGRAISGEDATGFLNTLGLRIGIEAARAGNT
GAGA
>Mature_404_residues
MKPKHILLAYSGGLDTSTALHFLKRHFDCRVTAYCANLGQKEDWERMKRRAAIAGADELVIEDLRETFIGDFVFPALKAN
ASYERDYLLGTPLARPAIVKGLIEYARKHDVDCLSHGCTQKGNDQVRFEMAAKILAPDLPTVAPWRIWSLQSREDLFAYC
QQHGIPVESRPDNLLSHDENLVHITTEGDYLESVANAFDWRDANWITPPTQAPDAIETITLGFRRGVPVSVDGAALGPVE
LVERLNEAGARNGVGFQDIIENRINGLKVRGVFENPALTILHAAHRKLEKITLGRDVERLRNLVSDDYGDIVYRGLWFSD
ERLCLQALIDESQKYVSGDVKVQLYKGSCTPCAVESEQSLYSRELVTLHAGRAISGEDATGFLNTLGLRIGIEAARAGNT
GAGA

Specific function: Arginine biosynthesis; seventh step. [C]

COG id: COG0137

COG function: function code E; Argininosuccinate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the argininosuccinate synthase family. Type 1 subfamily

Homologues:

Organism=Homo sapiens, GI53759107, Length=395, Percent_Identity=41.0126582278481, Blast_Score=288, Evalue=6e-78,
Organism=Homo sapiens, GI16950633, Length=395, Percent_Identity=41.0126582278481, Blast_Score=288, Evalue=6e-78,
Organism=Escherichia coli, GI1789563, Length=408, Percent_Identity=28.6764705882353, Blast_Score=132, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6324514, Length=405, Percent_Identity=37.037037037037, Blast_Score=247, Evalue=3e-66,
Organism=Drosophila melanogaster, GI21358151, Length=409, Percent_Identity=39.8533007334963, Blast_Score=281, Evalue=5e-76,

Paralogues:

None

Copy number: 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): ASSY_BURPS (Q63U95)

Other databases:

- EMBL:   BX571965
- RefSeq:   YP_108321.1
- ProteinModelPortal:   Q63U95
- SMR:   Q63U95
- GeneID:   3093741
- GenomeReviews:   BX571965_GR
- KEGG:   bps:BPSL1721
- HOGENOM:   HBG335267
- OMA:   PLIAKRQ
- PhylomeDB:   Q63U95
- ProtClustDB:   CLSK710080
- BioCyc:   BPSE272560:BPSL1721-MONOMER
- BRENDA:   6.3.4.5
- GO:   GO:0005737
- HAMAP:   MF_00005
- InterPro:   IPR001518
- InterPro:   IPR018223
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11587
- TIGRFAMs:   TIGR00032

Pfam domain/function: PF00764 Arginosuc_synth

EC number: =6.3.4.5

Molecular weight: Translated: 44744; Mature: 44744

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS00564 ARGININOSUCCIN_SYN_1; PS00565 ARGININOSUCCIN_SYN_2

Important sites: BINDING 36-36 BINDING 87-87 BINDING 117-117 BINDING 119-119 BINDING 123-123 BINDING 123-123 BINDING 124-124 BINDING 127-127 BINDING 176-176 BINDING 261-261

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPKHILLAYSGGLDTSTALHFLKRHFDCRVTAYCANLGQKEDWERMKRRAAIAGADELV
CCCCEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHCCHHHHH
IEDLRETFIGDFVFPALKANASYERDYLLGTPLARPAIVKGLIEYARKHDVDCLSHGCTQ
HHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHHCCHHHHHHCCCC
KGNDQVRFEMAAKILAPDLPTVAPWRIWSLQSREDLFAYCQQHGIPVESRPDNLLSHDEN
CCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCHHHCCCCC
LVHITTEGDYLESVANAFDWRDANWITPPTQAPDAIETITLGFRRGVPVSVDGAALGPVE
EEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCCHHH
LVERLNEAGARNGVGFQDIIENRINGLKVRGVFENPALTILHAAHRKLEKITLGRDVERL
HHHHHHHHCCCCCCCHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHH
RNLVSDDYGDIVYRGLWFSDERLCLQALIDESQKYVSGDVKVQLYKGSCTPCAVESEQSL
HHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHH
YSRELVTLHAGRAISGEDATGFLNTLGLRIGIEAARAGNTGAGA
HHHHHEEEECCCEECCCCCHHHHHHHHHHEEEHHHCCCCCCCCC
>Mature Secondary Structure
MKPKHILLAYSGGLDTSTALHFLKRHFDCRVTAYCANLGQKEDWERMKRRAAIAGADELV
CCCCEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHCCHHHHH
IEDLRETFIGDFVFPALKANASYERDYLLGTPLARPAIVKGLIEYARKHDVDCLSHGCTQ
HHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHHCCHHHHHHCCCC
KGNDQVRFEMAAKILAPDLPTVAPWRIWSLQSREDLFAYCQQHGIPVESRPDNLLSHDEN
CCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCHHHCCCCC
LVHITTEGDYLESVANAFDWRDANWITPPTQAPDAIETITLGFRRGVPVSVDGAALGPVE
EEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCCHHH
LVERLNEAGARNGVGFQDIIENRINGLKVRGVFENPALTILHAAHRKLEKITLGRDVERL
HHHHHHHHCCCCCCCHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHH
RNLVSDDYGDIVYRGLWFSDERLCLQALIDESQKYVSGDVKVQLYKGSCTPCAVESEQSL
HHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHH
YSRELVTLHAGRAISGEDATGFLNTLGLRIGIEAARAGNTGAGA
HHHHHEEEECCCEECCCCCHHHHHHHHHHEEEHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA