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The map label for this gene is napA [H]

Identifier: 53719246

GI number: 53719246

Start: 1872876

End: 1874255

Strand: Reverse

Name: napA [H]

Synonym: BPSL1616

Alternate gene names: 53719246

Gene position: 1874255-1872876 (Counterclockwise)

Preceding gene: 53719247

Following gene: 53719244

Centisome position: 46.0

GC content: 71.96

Gene sequence:

>1380_bases
ATGCCCCCGGCGCGCCCGCGCACCGAACGCGAGGAGCCAACGAAGATGGCTGACTGGATACTGCAACTGTGCGTCGTGGT
GGTCGTCGCATTCACGCTCGGCGCGCTCGCGCAACGGCTCGGGCAAGGCCGGGTCGTCGGCGAGCTGCTCGCCGGGCTGC
TGCTCGGCCCGTCGGCGTTCGGCGCGCTCACCGTGGCGGGGCACGGCGCGCTGATCGGCCCGCAGACGGCCGCGCTCCTC
TCGCGGCTCGGCGAACTCGGTCTCGTGTTCCTGATGTTCCAGACGGGCATGCACATCACCTGGACGACGGCGCACGGGCG
CTCGTCCGGGCTCGTCGCGACCGTCGTCGCGGGGTTCGGCATGGCGCTGCCGTTCGCGACGGGCTGCGCGATCGCCGTCG
CGGCGTCCGGATCGTTCCAGCCGCAGGCGTCGCATCTCGCCTATGTGCTGTTCTGCGGGATCGCGCTGTCCGTGTCGGCG
CTGCCCGTCATGATGCGCATCATCGCGGACGCGCGCATCGCCGGGCGCGCGTGCGCGACGCTATCGATACTCGCGGCGAC
GTTGACCGATTCGCTCGGCTGGCTGATGCTCGCGGCCGTCGGCACGCTCGCGACCTCGGGCCTGTCGCCCGCCTCGACGG
TGCACGCGATGGGCATGCTCGTCGCGTTCGTCGTCGTGTCGATCTCGCTCGTGCGCCCCATCGTGCTCGGCGTGCTCGAT
CGAACGCGCCGGGCCGGCAGCGGCTCCGCCATGTTGATCTGCGCGCTCTGCTACGTGCTGCTGTCGTCGTGGGCCGCGGC
GCGGCTCGGCTTTCACGGCGCGTTCGGCGCGCTCGTCGCGGCCGCCAACCTCGCGGGGCGCCACGACCTGCGCCAGCTGT
GGGACGCGCGCTTCGCCGGCCTCGCCGATCTCGTGCTGATTCCGCTCTTCTTCGTCAGCATGGGCTTTCAGGCATCGTTC
TCCGCGCTCGACACGGGCGCGGCCTGGGGCTGGCTCGCCGCGTTTCTCGTCGGCGGCGTGGCGACGAAATTCGCCGGCTG
CTACGCGGGCGCGCGACTGTGCGGCATCGACCGCGCGGAGGCGACGCTCGTGGGCGTGCTGATGAACTGCCGCGGCACGG
TCGAGCTGATGGTGCTCGCGATCGGCCTGCAGTTGCGGATCATTCCCGCTTCGCTGTACACGGTCCTGCTGATCGCGACG
CTGACGATGACGTGGTTGAGCGCGATGTCGACCCATCGGCTCGCGAAGCGGCGCCCGCTGCGCTCGCCGCCGGCGGGCGC
GAGCGACGCGCCGGCGGGATTTCGCGCGACGCAGGCTCAGGCGGCAGGCGGCGACGCCCGTCTGCCAGGATTGCCGGAGG
CATCGCGCCCGTCGCGATGA

Upstream 100 bases:

>100_bases
GACGGGCTCTACGTATCGACCCGGCCTCGGCTCGGCCTGCAGCGCGTCGCCGCGATGTAACCCGCGGCGGGCGCGCCGAC
GCGCGGGCGCGCGGGCGCGC

Downstream 100 bases:

>100_bases
ATACCCATGGATACCATCGTTCCGTTTCTTTCCGATTCCACCGCACGCTGGCTGCCGCTCGCGCTGTCCGAACAGGTGAG
CGGCAAGGCCCCGCTCGCCG

Product: putative transport related membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 458

Protein sequence:

>459_residues
MPPARPRTEREEPTKMADWILQLCVVVVVAFTLGALAQRLGQGRVVGELLAGLLLGPSAFGALTVAGHGALIGPQTAALL
SRLGELGLVFLMFQTGMHITWTTAHGRSSGLVATVVAGFGMALPFATGCAIAVAASGSFQPQASHLAYVLFCGIALSVSA
LPVMMRIIADARIAGRACATLSILAATLTDSLGWLMLAAVGTLATSGLSPASTVHAMGMLVAFVVVSISLVRPIVLGVLD
RTRRAGSGSAMLICALCYVLLSSWAAARLGFHGAFGALVAAANLAGRHDLRQLWDARFAGLADLVLIPLFFVSMGFQASF
SALDTGAAWGWLAAFLVGGVATKFAGCYAGARLCGIDRAEATLVGVLMNCRGTVELMVLAIGLQLRIIPASLYTVLLIAT
LTMTWLSAMSTHRLAKRRPLRSPPAGASDAPAGFRATQAQAAGGDARLPGLPEASRPSR

Sequences:

>Translated_459_residues
MPPARPRTEREEPTKMADWILQLCVVVVVAFTLGALAQRLGQGRVVGELLAGLLLGPSAFGALTVAGHGALIGPQTAALL
SRLGELGLVFLMFQTGMHITWTTAHGRSSGLVATVVAGFGMALPFATGCAIAVAASGSFQPQASHLAYVLFCGIALSVSA
LPVMMRIIADARIAGRACATLSILAATLTDSLGWLMLAAVGTLATSGLSPASTVHAMGMLVAFVVVSISLVRPIVLGVLD
RTRRAGSGSAMLICALCYVLLSSWAAARLGFHGAFGALVAAANLAGRHDLRQLWDARFAGLADLVLIPLFFVSMGFQASF
SALDTGAAWGWLAAFLVGGVATKFAGCYAGARLCGIDRAEATLVGVLMNCRGTVELMVLAIGLQLRIIPASLYTVLLIAT
LTMTWLSAMSTHRLAKRRPLRSPPAGASDAPAGFRATQAQAAGGDARLPGLPEASRPSR
>Mature_458_residues
PPARPRTEREEPTKMADWILQLCVVVVVAFTLGALAQRLGQGRVVGELLAGLLLGPSAFGALTVAGHGALIGPQTAALLS
RLGELGLVFLMFQTGMHITWTTAHGRSSGLVATVVAGFGMALPFATGCAIAVAASGSFQPQASHLAYVLFCGIALSVSAL
PVMMRIIADARIAGRACATLSILAATLTDSLGWLMLAAVGTLATSGLSPASTVHAMGMLVAFVVVSISLVRPIVLGVLDR
TRRAGSGSAMLICALCYVLLSSWAAARLGFHGAFGALVAAANLAGRHDLRQLWDARFAGLADLVLIPLFFVSMGFQASFS
ALDTGAAWGWLAAFLVGGVATKFAGCYAGARLCGIDRAEATLVGVLMNCRGTVELMVLAIGLQLRIIPASLYTVLLIATL
TMTWLSAMSTHRLAKRRPLRSPPAGASDAPAGFRATQAQAAGGDARLPGLPEASRPSR

Specific function: This is a Na(+)/H(+) antiporter. It can mediate sodium uptake when a transmembrane pH gradient is applied [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322367, Length=458, Percent_Identity=25.1091703056769, Blast_Score=154, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 47385; Mature: 47253

Theoretical pI: Translated: 10.49; Mature: 10.49

Prosite motif: PS00436 PEROXIDASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPARPRTEREEPTKMADWILQLCVVVVVAFTLGALAQRLGQGRVVGELLAGLLLGPSAF
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHH
GALTVAGHGALIGPQTAALLSRLGELGLVFLMFQTGMHITWTTAHGRSSGLVATVVAGFG
CCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHH
MALPFATGCAIAVAASGSFQPQASHLAYVLFCGIALSVSALPVMMRIIADARIAGRACAT
HHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSILAATLTDSLGWLMLAAVGTLATSGLSPASTVHAMGMLVAFVVVSISLVRPIVLGVLD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTRRAGSGSAMLICALCYVLLSSWAAARLGFHGAFGALVAAANLAGRHDLRQLWDARFAG
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LADLVLIPLFFVSMGFQASFSALDTGAAWGWLAAFLVGGVATKFAGCYAGARLCGIDRAE
HHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHH
ATLVGVLMNCRGTVELMVLAIGLQLRIIPASLYTVLLIATLTMTWLSAMSTHRLAKRRPL
HHHHHHHHHCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RSPPAGASDAPAGFRATQAQAAGGDARLPGLPEASRPSR
CCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PPARPRTEREEPTKMADWILQLCVVVVVAFTLGALAQRLGQGRVVGELLAGLLLGPSAF
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHH
GALTVAGHGALIGPQTAALLSRLGELGLVFLMFQTGMHITWTTAHGRSSGLVATVVAGFG
CCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHH
MALPFATGCAIAVAASGSFQPQASHLAYVLFCGIALSVSALPVMMRIIADARIAGRACAT
HHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSILAATLTDSLGWLMLAAVGTLATSGLSPASTVHAMGMLVAFVVVSISLVRPIVLGVLD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTRRAGSGSAMLICALCYVLLSSWAAARLGFHGAFGALVAAANLAGRHDLRQLWDARFAG
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LADLVLIPLFFVSMGFQASFSALDTGAAWGWLAAFLVGGVATKFAGCYAGARLCGIDRAE
HHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHH
ATLVGVLMNCRGTVELMVLAIGLQLRIIPASLYTVLLIATLTMTWLSAMSTHRLAKRRPL
HHHHHHHHHCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RSPPAGASDAPAGFRATQAQAAGGDARLPGLPEASRPSR
CCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1312090; 1325937 [H]