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The map label for this gene is trxA [H]

Identifier: 53719131

GI number: 53719131

Start: 1734652

End: 1734978

Strand: Reverse

Name: trxA [H]

Synonym: BPSL1497

Alternate gene names: 53719131

Gene position: 1734978-1734652 (Counterclockwise)

Preceding gene: 53719141

Following gene: 53719130

Centisome position: 42.58

GC content: 61.77

Gene sequence:

>327_bases
ATGAGCGAACAGATCAAACACATCAGCGACGCATCGTTCGAGCAGGACGTCGTCAAGTCCGACAAGCCGGTCCTGCTGGA
CTTCTGGGCCGAGTGGTGCGGTCCGTGCAAGATGATCGCGCCGATCCTCGACGAAGTCGCGAAGGACTACGGCGACAAGC
TGCAGATCGCGAAGATCAACGTCGACGAAAATCAGGCGACGCCCGCGAAGTTCGGCGTGCGCGGCATCCCGACGCTGATC
CTCTTCAAGAACGGCGCGGTCGCCGCGCAGAAGGTCGGCGCGCTGTCGAAGTCGCAGCTCACCGCGTTCCTGGACAGCCA
TCTCTAA

Upstream 100 bases:

>100_bases
CCCTTCTTTTCGCAAGAGCGGAGCTTCCTGCCCCGGCGACCGGCATGGCCCACGGGCGGCCGGCGCAGGCAGTCCCCGAA
CCGAAAGAGGTATTGACCCA

Downstream 100 bases:

>100_bases
AACCGGATGCGCCCCGCGCACGTGTTGTCAACCGGCAACACGTGCGCCGCGAAATCCGCCGATCGGTCGCTCAAGCCCGA
ATCGGCCTATGCTAGAATCA

Product: thioredoxin 1

Products: NA

Alternate protein names: Trx [H]

Number of amino acids: Translated: 108; Mature: 107

Protein sequence:

>108_residues
MSEQIKHISDASFEQDVVKSDKPVLLDFWAEWCGPCKMIAPILDEVAKDYGDKLQIAKINVDENQATPAKFGVRGIPTLI
LFKNGAVAAQKVGALSKSQLTAFLDSHL

Sequences:

>Translated_108_residues
MSEQIKHISDASFEQDVVKSDKPVLLDFWAEWCGPCKMIAPILDEVAKDYGDKLQIAKINVDENQATPAKFGVRGIPTLI
LFKNGAVAAQKVGALSKSQLTAFLDSHL
>Mature_107_residues
SEQIKHISDASFEQDVVKSDKPVLLDFWAEWCGPCKMIAPILDEVAKDYGDKLQIAKINVDENQATPAKFGVRGIPTLIL
FKNGAVAAQKVGALSKSQLTAFLDSHL

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI21361403, Length=93, Percent_Identity=41.9354838709677, Blast_Score=79, Evalue=1e-15,
Organism=Homo sapiens, GI5031973, Length=100, Percent_Identity=28, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI87082331, Length=108, Percent_Identity=64.8148148148148, Blast_Score=157, Evalue=2e-40,
Organism=Escherichia coli, GI1788936, Length=92, Percent_Identity=40.2173913043478, Blast_Score=92, Evalue=8e-21,
Organism=Escherichia coli, GI87081747, Length=84, Percent_Identity=38.0952380952381, Blast_Score=69, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI212646193, Length=112, Percent_Identity=33.9285714285714, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17554386, Length=87, Percent_Identity=40.2298850574713, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17509965, Length=76, Percent_Identity=40.7894736842105, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71998175, Length=87, Percent_Identity=40.2298850574713, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71980565, Length=85, Percent_Identity=41.1764705882353, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71980562, Length=83, Percent_Identity=39.7590361445783, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17556044, Length=103, Percent_Identity=26.2135922330097, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321648, Length=94, Percent_Identity=40.4255319148936, Blast_Score=74, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6323072, Length=90, Percent_Identity=41.1111111111111, Blast_Score=72, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319925, Length=90, Percent_Identity=31.1111111111111, Blast_Score=62, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24639826, Length=94, Percent_Identity=41.4893617021277, Blast_Score=89, Evalue=6e-19,
Organism=Drosophila melanogaster, GI28573567, Length=92, Percent_Identity=35.8695652173913, Blast_Score=80, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24664269, Length=75, Percent_Identity=41.3333333333333, Blast_Score=75, Evalue=6e-15,
Organism=Drosophila melanogaster, GI17648013, Length=78, Percent_Identity=39.7435897435897, Blast_Score=73, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24583090, Length=78, Percent_Identity=39.7435897435897, Blast_Score=73, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24639068, Length=93, Percent_Identity=32.258064516129, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: NA

Molecular weight: Translated: 11815; Mature: 11684

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQIKHISDASFEQDVVKSDKPVLLDFWAEWCGPCKMIAPILDEVAKDYGDKLQIAKIN
CCCCHHHCCCCCHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEE
VDENQATPAKFGVRGIPTLILFKNGAVAAQKVGALSKSQLTAFLDSHL
CCCCCCCCHHCCCCCCCEEEEEECCCHHHHHHCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
SEQIKHISDASFEQDVVKSDKPVLLDFWAEWCGPCKMIAPILDEVAKDYGDKLQIAKIN
CCCHHHCCCCCHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEE
VDENQATPAKFGVRGIPTLILFKNGAVAAQKVGALSKSQLTAFLDSHL
CCCCCCCCHHCCCCCCCEEEEEECCCHHHHHHCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10224002; 10984043 [H]