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The map label for this gene is dinF [H]

Identifier: 53719017

GI number: 53719017

Start: 1606854

End: 1608245

Strand: Reverse

Name: dinF [H]

Synonym: BPSL1378

Alternate gene names: 53719017

Gene position: 1608245-1606854 (Counterclockwise)

Preceding gene: 53719018

Following gene: 53719015

Centisome position: 39.47

GC content: 69.9

Gene sequence:

>1392_bases
ATGTCCGCCTCCTCCCCTCCGACGCACGCAGACGAAGACCCCGAGCCGCGCGCTGCCGCGAACGGGCATCGGCGCGTGCT
CGGCCTCGCGTTGCCCATCATCGCGGCCAATCTCACGCAGCCGATTCTCGGCGCGGTCGACACCGCCGTCGCCGGTCACC
TGAACGGCCCGCAATATCTCGGCGGCGTCGCACTCGGCGGCCTCTTCTTCAATTTCGTGTACTGGGGCTTCGGCTTCCTG
CGAATGGGGACGACGGGGCTCGTCGCGCAAGCGTTCGGCGCGAACGACCTCGCCGGAATCCGCATCAACGTACTGCGCGC
GCTCCTGCTCGCGTTCACGCTCGGCGCGGCGGTGCTCGCGCTGCAAACGCCGCTGCTCGGCATCGCGTTCGCCGCGCTCG
GCGGCAGCGATTCGGTTCGCTCGACTGCGCTCGAATACGCGCACGCGCGGATCTGGGCCGCGCCGTTCGCGCTCGCGAAT
TACGTCGTGCTCGGCTATCTGCTCGGCATGCAACGCGTGCGTCTCGCACTCGTGATCCAGGTGCTCGTGAACGTCGTCAA
CATCGGCGCGGTGCTGCTCTACGTGTACCGCTTCGATTGGGGCGTCGCAGGCATCGGCGCCGCGACCGCGACGGCCGACA
TTGCCGGCTTCGCGGCGAGCGCGCTGCTGCTGCGCTGGCTGAACCCGCGCGGCCTCGCGAAGATCAGGCGCGTCGAGCTC
TTCGATCGCGCGGCGCTCGCACGTCTCGTCGCGCTCAATCGCGACATCTTCATCCGCACGCTGTGTCTGCTGTCGGCGTT
CGGCTGGTTCGCGCATCTCGGTGCGCGACAAGGCGACGCGACGCTCGCCGCCAACGCGCTGCTGCTCAATTTCCAGACCT
TCATGGCGTACGCGCTCGACGGCTTCGCGCATGCGGCGGAAGCGCTTGTCGGCGCGGCGGCCGGCGCGCGCAATCGCGAT
GCATTCCGCCAAGCGCTGCGCACGACGTTCTTCTGGGCGGGGATCGGCGCGCTCGCGTTCGCGCTCGCCTATTGGTGCGC
GGGCGGCTGGATCGTCGCGCAACTCACCGATCAGCCGTCCGTGCGGGGCGTCGCCGAACGTTATCTCCCGTGGGCCGCGC
TCTCACCGGTGATTTCCGTCTGGGGTTTCATGCTCGACGGCGTGTTCATCGGCGCGACGCACACGCGCGCGCTGATGCGG
GCCATGGCGACATCGTTCGCGCTGTTCGTCGCCGCAACGCTCGCGCTGGTCGGCCCGCTCGGCAATCACGGGCTCTGGAT
CGCATTGCTCGTGTTCATGGCCGCGCGCGGCGCGACGCTCGCGCGCCGTCTGCCGGGGCTCGAGCGAGCCGTCGCACCGG
ATGCGGCGCGAGCGCCGAGCGCGGCCGGCTGA

Upstream 100 bases:

>100_bases
CAGGCCGGCACCGCGCAGGATTACGCGACGCGCAATCCCGAGCTGTGGGCGGTCGTCGTATCGCCGTGGGTGTGCGTGCA
GGCACGCTCGTAACACCGCG

Downstream 100 bases:

>100_bases
CCCGCATGTCGGCCGCGTAGCCCTACAGCGGAAACACGGCGAAAGCACGGCCGAAGCGCGGCGGCAATCCGCATCGCCCA
TCGCCTATCGCCCATTTGCC

Product: putative membrane protein (DNA-damage-inducible protein)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MSASSPPTHADEDPEPRAAANGHRRVLGLALPIIAANLTQPILGAVDTAVAGHLNGPQYLGGVALGGLFFNFVYWGFGFL
RMGTTGLVAQAFGANDLAGIRINVLRALLLAFTLGAAVLALQTPLLGIAFAALGGSDSVRSTALEYAHARIWAAPFALAN
YVVLGYLLGMQRVRLALVIQVLVNVVNIGAVLLYVYRFDWGVAGIGAATATADIAGFAASALLLRWLNPRGLAKIRRVEL
FDRAALARLVALNRDIFIRTLCLLSAFGWFAHLGARQGDATLAANALLLNFQTFMAYALDGFAHAAEALVGAAAGARNRD
AFRQALRTTFFWAGIGALAFALAYWCAGGWIVAQLTDQPSVRGVAERYLPWAALSPVISVWGFMLDGVFIGATHTRALMR
AMATSFALFVAATLALVGPLGNHGLWIALLVFMAARGATLARRLPGLERAVAPDAARAPSAAG

Sequences:

>Translated_463_residues
MSASSPPTHADEDPEPRAAANGHRRVLGLALPIIAANLTQPILGAVDTAVAGHLNGPQYLGGVALGGLFFNFVYWGFGFL
RMGTTGLVAQAFGANDLAGIRINVLRALLLAFTLGAAVLALQTPLLGIAFAALGGSDSVRSTALEYAHARIWAAPFALAN
YVVLGYLLGMQRVRLALVIQVLVNVVNIGAVLLYVYRFDWGVAGIGAATATADIAGFAASALLLRWLNPRGLAKIRRVEL
FDRAALARLVALNRDIFIRTLCLLSAFGWFAHLGARQGDATLAANALLLNFQTFMAYALDGFAHAAEALVGAAAGARNRD
AFRQALRTTFFWAGIGALAFALAYWCAGGWIVAQLTDQPSVRGVAERYLPWAALSPVISVWGFMLDGVFIGATHTRALMR
AMATSFALFVAATLALVGPLGNHGLWIALLVFMAARGATLARRLPGLERAVAPDAARAPSAAG
>Mature_462_residues
SASSPPTHADEDPEPRAAANGHRRVLGLALPIIAANLTQPILGAVDTAVAGHLNGPQYLGGVALGGLFFNFVYWGFGFLR
MGTTGLVAQAFGANDLAGIRINVLRALLLAFTLGAAVLALQTPLLGIAFAALGGSDSVRSTALEYAHARIWAAPFALANY
VVLGYLLGMQRVRLALVIQVLVNVVNIGAVLLYVYRFDWGVAGIGAATATADIAGFAASALLLRWLNPRGLAKIRRVELF
DRAALARLVALNRDIFIRTLCLLSAFGWFAHLGARQGDATLAANALLLNFQTFMAYALDGFAHAAEALVGAAAGARNRDA
FRQALRTTFFWAGIGALAFALAYWCAGGWIVAQLTDQPSVRGVAERYLPWAALSPVISVWGFMLDGVFIGATHTRALMRA
MATSFALFVAATLALVGPLGNHGLWIALLVFMAARGATLARRLPGLERAVAPDAARAPSAAG

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790477, Length=418, Percent_Identity=43.0622009569378, Blast_Score=242, Evalue=3e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 48699; Mature: 48568

Theoretical pI: Translated: 10.71; Mature: 10.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASSPPTHADEDPEPRAAANGHRRVLGLALPIIAANLTQPILGAVDTAVAGHLNGPQYL
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
GGVALGGLFFNFVYWGFGFLRMGTTGLVAQAFGANDLAGIRINVLRALLLAFTLGAAVLA
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LQTPLLGIAFAALGGSDSVRSTALEYAHARIWAAPFALANYVVLGYLLGMQRVRLALVIQ
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLVNVVNIGAVLLYVYRFDWGVAGIGAATATADIAGFAASALLLRWLNPRGLAKIRRVEL
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
FDRAALARLVALNRDIFIRTLCLLSAFGWFAHLGARQGDATLAANALLLNFQTFMAYALD
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
GFAHAAEALVGAAAGARNRDAFRQALRTTFFWAGIGALAFALAYWCAGGWIVAQLTDQPS
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
VRGVAERYLPWAALSPVISVWGFMLDGVFIGATHTRALMRAMATSFALFVAATLALVGPL
HHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GNHGLWIALLVFMAARGATLARRLPGLERAVAPDAARAPSAAG
CCCHHHHHHHHHHHHCCHHHHHHCCCCHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SASSPPTHADEDPEPRAAANGHRRVLGLALPIIAANLTQPILGAVDTAVAGHLNGPQYL
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
GGVALGGLFFNFVYWGFGFLRMGTTGLVAQAFGANDLAGIRINVLRALLLAFTLGAAVLA
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LQTPLLGIAFAALGGSDSVRSTALEYAHARIWAAPFALANYVVLGYLLGMQRVRLALVIQ
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLVNVVNIGAVLLYVYRFDWGVAGIGAATATADIAGFAASALLLRWLNPRGLAKIRRVEL
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
FDRAALARLVALNRDIFIRTLCLLSAFGWFAHLGARQGDATLAANALLLNFQTFMAYALD
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
GFAHAAEALVGAAAGARNRDAFRQALRTTFFWAGIGALAFALAYWCAGGWIVAQLTDQPS
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
VRGVAERYLPWAALSPVISVWGFMLDGVFIGATHTRALMRAMATSFALFVAATLALVGPL
HHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GNHGLWIALLVFMAARGATLARRLPGLERAVAPDAARAPSAAG
CCCHHHHHHHHHHHHCCHHHHHHCCCCHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]