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The map label for this gene is can [H]

Identifier: 53718839

GI number: 53718839

Start: 1387935

End: 1388570

Strand: Reverse

Name: can [H]

Synonym: BPSL1203

Alternate gene names: 53718839

Gene position: 1388570-1387935 (Counterclockwise)

Preceding gene: 53718840

Following gene: 53718838

Centisome position: 34.08

GC content: 71.7

Gene sequence:

>636_bases
ATGAATCGCCCGAAAAGCATGCTCGTCGCCAATATCGCCTGGGCCCGCGAGACGTCCGAGCGCTCGCCCGACTTCTTCGA
CGCGCTGTCGCGCGGCCAGAACCCGCGCGTGCTGTGGATCGGCTGCGCCGACAGCCGCGTGCCGGCCGAAGCCATCACAC
AGAGTGCGCCAGGCGAACTATTCGTTCACCGAAACATCGCGAACATCTTCCAGCCCGACGACGACAACTGCGCGAGCGTG
CTCGAGTACGCGGTCAAGGTGCTGAAGGTCGATCACGTGATCGTCTGCGGGCACTACGGCTGCGGCGGCGTGCGCGCGTC
GCTCCTGCCGCCGTCGCCCGAGCTGCCGCACGTGAACCGCCGGATCGCGCCGCTGTGCGCGCTCGCCGGCCGCCATCGCG
CGGAGCTCGACGGCGTGCCGCCCGACGCGGCCGCCGACCGGCTCGCCGAGCTCAACGTGCTCGAGCAGGTGCGGCTGCTG
CGCAGCTCGCCGATCATCCGCGACGCCGCCCCCGCCCCGCTCGTGCACGGCTGGATCTTCTCGCTCGCCGACGGCCGCCT
CAAGGAACTCGCGTCCGGCTACCCGGCGGCGCAACGGCCGCCGCAAGCCGAACGCGCGCAAGCCGCGGCCGCCTGA

Upstream 100 bases:

>100_bases
CTAATATCACTCACAACAACCTTTCAATTTAGAAAGAAATTGGTTCCGCGCCGATGCATCTTTGCGTCGTCGCCATCGCA
CGCATAAGAAGGAATCCTCA

Downstream 100 bases:

>100_bases
GCCGCGGCCGCCGCGACATCGCACCCCAAGTCTCAACCCGTTTTTTTCTCGCTCACTATGAAGAATCTACGCGCTTCCTT
TTCCACGTTTCCGCGCGACT

Product: putative carbonic anhydrase

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MNRPKSMLVANIAWARETSERSPDFFDALSRGQNPRVLWIGCADSRVPAEAITQSAPGELFVHRNIANIFQPDDDNCASV
LEYAVKVLKVDHVIVCGHYGCGGVRASLLPPSPELPHVNRRIAPLCALAGRHRAELDGVPPDAAADRLAELNVLEQVRLL
RSSPIIRDAAPAPLVHGWIFSLADGRLKELASGYPAAQRPPQAERAQAAAA

Sequences:

>Translated_211_residues
MNRPKSMLVANIAWARETSERSPDFFDALSRGQNPRVLWIGCADSRVPAEAITQSAPGELFVHRNIANIFQPDDDNCASV
LEYAVKVLKVDHVIVCGHYGCGGVRASLLPPSPELPHVNRRIAPLCALAGRHRAELDGVPPDAAADRLAELNVLEQVRLL
RSSPIIRDAAPAPLVHGWIFSLADGRLKELASGYPAAQRPPQAERAQAAAA
>Mature_211_residues
MNRPKSMLVANIAWARETSERSPDFFDALSRGQNPRVLWIGCADSRVPAEAITQSAPGELFVHRNIANIFQPDDDNCASV
LEYAVKVLKVDHVIVCGHYGCGGVRASLLPPSPELPHVNRRIAPLCALAGRHRAELDGVPPDAAADRLAELNVLEQVRLL
RSSPIIRDAAPAPLVHGWIFSLADGRLKELASGYPAAQRPPQAERAQAAAA

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=193, Percent_Identity=44.0414507772021, Blast_Score=176, Evalue=1e-45,
Organism=Escherichia coli, GI1786534, Length=192, Percent_Identity=31.25, Blast_Score=92, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6324292, Length=203, Percent_Identity=29.5566502463054, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 22798; Mature: 22798

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRPKSMLVANIAWARETSERSPDFFDALSRGQNPRVLWIGCADSRVPAEAITQSAPGEL
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCHHHHHCCCCCCE
FVHRNIANIFQPDDDNCASVLEYAVKVLKVDHVIVCGHYGCGGVRASLLPPSPELPHVNR
EEECCHHHHCCCCCCCHHHHHHHHHHHHHHCEEEEECCCCCCCCEECCCCCCCCCCCCCH
RIAPLCALAGRHRAELDGVPPDAAADRLAELNVLEQVRLLRSSPIIRDAAPAPLVHGWIF
HHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
SLADGRLKELASGYPAAQRPPQAERAQAAAA
HHCCHHHHHHHCCCCCCCCCCHHHHHHHCCC
>Mature Secondary Structure
MNRPKSMLVANIAWARETSERSPDFFDALSRGQNPRVLWIGCADSRVPAEAITQSAPGEL
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCHHHHHCCCCCCE
FVHRNIANIFQPDDDNCASVLEYAVKVLKVDHVIVCGHYGCGGVRASLLPPSPELPHVNR
EEECCHHHHCCCCCCCHHHHHHHHHHHHHHCEEEEECCCCCCCCEECCCCCCCCCCCCCH
RIAPLCALAGRHRAELDGVPPDAAADRLAELNVLEQVRLLRSSPIIRDAAPAPLVHGWIF
HHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
SLADGRLKELASGYPAAQRPPQAERAQAAAA
HHCCHHHHHHHCCCCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10493123 [H]