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The map label for this gene is rlmH

Identifier: 53718796

GI number: 53718796

Start: 1339795

End: 1340265

Strand: Reverse

Name: rlmH

Synonym: BPSL1160

Alternate gene names: 53718796

Gene position: 1340265-1339795 (Counterclockwise)

Preceding gene: 53718797

Following gene: 53718795

Centisome position: 32.89

GC content: 71.13

Gene sequence:

>471_bases
ATGAAACTGCACATCGTCGCGGTCGGCCACAAGATGCCCGGCTGGATCGCGTCCGGCTTCGACGAGTACGCGAAGCGGAT
GCCGCCCGAGCTGCGCATCGAGCTGCGCGAAGTGAAGCCCGAACTGCGCTCGGGCTCGCGCACGGCCGACAGCGTGATGG
CCGCCGAGCAGCAGCGGATCGAAGCCGCGCTGCCGAAGAACGCGCGCGTCGTCGCACTCGACGAGCGCGGCCGCGACTGG
ACCACGATGCAGCTCGCGCAGGCGCTGCCCGCGTGGCAGCAGGACGGCCGCGACGTCGCGTTCGTGATCGGCGGCGCCGA
CGGGCTCGCCCCGGCGCTCAAGTCGCGCGCCGAGCTGCTGCTGCGCGTGTCGAGCCTCACGCTGCCGCACGGCATGGTGC
GCGTGCTGCTCGCCGAGCAGCTTTACCGCGCGTGGAGCATCACGCAGAATCACCCCTACCATCGCGCGTAG

Upstream 100 bases:

>100_bases
CCGCGCGCCCCGCCCGCAAGGCGACGGCCGCGCGCCGCCGCTGAGCGCGCGCCGCCGTTTCGTCGCCTTCATTGTTGTCG
CTTTCGTCGCGTTCGCCGTC

Downstream 100 bases:

>100_bases
CGGTGCGTCGCCCCGACGCGCCGCGCACGCGCCCATCGAGACTACCGATCAGATGCCCGAGCACGCCGCCCCGTCCTACC
CGTTCGTCTACCTCGCCTCG

Product: rRNA large subunit methyltransferase

Products: NA

Alternate protein names: 23S rRNA m3Psi1915 methyltransferase; rRNA (pseudouridine-N3-)-methyltransferase rlmH

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MKLHIVAVGHKMPGWIASGFDEYAKRMPPELRIELREVKPELRSGSRTADSVMAAEQQRIEAALPKNARVVALDERGRDW
TTMQLAQALPAWQQDGRDVAFVIGGADGLAPALKSRAELLLRVSSLTLPHGMVRVLLAEQLYRAWSITQNHPYHRA

Sequences:

>Translated_156_residues
MKLHIVAVGHKMPGWIASGFDEYAKRMPPELRIELREVKPELRSGSRTADSVMAAEQQRIEAALPKNARVVALDERGRDW
TTMQLAQALPAWQQDGRDVAFVIGGADGLAPALKSRAELLLRVSSLTLPHGMVRVLLAEQLYRAWSITQNHPYHRA
>Mature_156_residues
MKLHIVAVGHKMPGWIASGFDEYAKRMPPELRIELREVKPELRSGSRTADSVMAAEQQRIEAALPKNARVVALDERGRDW
TTMQLAQALPAWQQDGRDVAFVIGGADGLAPALKSRAELLLRVSSLTLPHGMVRVLLAEQLYRAWSITQNHPYHRA

Specific function: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA

COG id: COG1576

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase rlmH family

Homologues:

Organism=Escherichia coli, GI1786855, Length=155, Percent_Identity=50.9677419354839, Blast_Score=155, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RLMH_BURM7 (A3MI42)

Other databases:

- EMBL:   CP000548
- RefSeq:   YP_001079928.1
- ProteinModelPortal:   A3MI42
- SMR:   A3MI42
- GeneID:   4893958
- GenomeReviews:   CP000548_GR
- KEGG:   bmn:BMA10247_0353
- TIGR:   BMA10247_0353
- HOGENOM:   HBG622807
- OMA:   TANHPYH
- ProtClustDB:   PRK00103
- BioCyc:   BMAL320389:BMA10247_0353-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00658
- InterPro:   IPR016051
- InterPro:   IPR003742
- PIRSF:   PIRSF004505
- TIGRFAMs:   TIGR00246

Pfam domain/function: PF02590 SPOUT_MTase

EC number: NA

Molecular weight: Translated: 17427; Mature: 17427

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLHIVAVGHKMPGWIASGFDEYAKRMPPELRIELREVKPELRSGSRTADSVMAAEQQRI
CEEEEEEECCCCCCHHHHCHHHHHHHCCHHHHHHHHHHCHHHHCCCCCHHHHHHHHHHHH
EAALPKNARVVALDERGRDWTTMQLAQALPAWQQDGRDVAFVIGGADGLAPALKSRAELL
HHHCCCCCEEEEECCCCCCHHHHHHHHHCCHHHHCCCEEEEEEECCCHHHHHHHHHHHHH
LRVSSLTLPHGMVRVLLAEQLYRAWSITQNHPYHRA
HHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKLHIVAVGHKMPGWIASGFDEYAKRMPPELRIELREVKPELRSGSRTADSVMAAEQQRI
CEEEEEEECCCCCCHHHHCHHHHHHHCCHHHHHHHHHHCHHHHCCCCCHHHHHHHHHHHH
EAALPKNARVVALDERGRDWTTMQLAQALPAWQQDGRDVAFVIGGADGLAPALKSRAELL
HHHCCCCCEEEEECCCCCCHHHHHHHHHCCHHHHCCCEEEEEEECCCHHHHHHHHHHHHH
LRVSSLTLPHGMVRVLLAEQLYRAWSITQNHPYHRA
HHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA