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The map label for this gene is gluQ

Identifier: 53718750

GI number: 53718750

Start: 1293310

End: 1294203

Strand: Reverse

Name: gluQ

Synonym: BPSL1115

Alternate gene names: 53718750

Gene position: 1294203-1293310 (Counterclockwise)

Preceding gene: 53718751

Following gene: 53718745

Centisome position: 31.76

GC content: 74.16

Gene sequence:

>894_bases
ATGACACGCTATCGCGGGCGCTTCGCGCCGTCGCCCACCGGCCCCCTGCACTTCGGCTCGCTCGTCGGCGCGCTCGCGAG
CTGGCTCGACGCGCGCGCGTGGGGCGGCGCGTGGCTCGTGCGAATCGAGGATATCGACGGCCCGCGCACGGTGCCAGGCG
CGGCCGAAGACATGCTCGCGACGCTGCGCGGCTTCGGCTTCATCGCCGACGAGCCGCCCGTCTGGCAAAGCGCGCGCGTC
GCGCACTACGAAGCGGCGCTCGCGCGGCTCACCGCCGCGGGGCTCGTCTATCCGTGCGGCTGCTCGCGCAAGGAGATCGC
CGATTCGCTGCGCGCCGCGCACGAGCGGCACACGACGCTCGCGTATCCCGGCACGTGCCGCACGGGCCTGCACGGCAAGC
CCGCGCGCGCATGGCGCTTGCGCGTGCCGGACGGCGCCGCGGCCGTCGTCGCGTTCGACGACCGCTGGCAGCGCGCGCAA
ACGCAGAATCTCGCGACCGAAGTCGGCGATTTCGTGCTGAAGCGCGCGGACGGACAATGGGCGTATCAACTCGCCGTCGT
CGTCGACGACGGCGATGCGAACATCACGCACGTCGTGCGCGGCGCCGATCTGCTCGACTCGACCGCTCGCCAGATCTACC
TGCAGCGCTGCCTCGGGCTGCCGACGCCGCGCTATCTGCACGTGCCTGTCGTCCTCGACGCGAACGGCGAGAAGCTCAGC
AAGCAAACGGGCGCGGCGGCGCTCGATCCCGCCGCGCCGCTGCCGGCGCTCGCCGCCGCCGCGCGGCACCTGGGGCTCGC
GCTCGACGGCGCGGCGTGCGCGTCGCTCGACGCGTTCCAGGCGGCCGCGATCGCCGCGTGGGACGCGCGCTTCGGGCCGA
ACGCGCGCGGCTGA

Upstream 100 bases:

>100_bases
TCCGGCACGCCGGGCCGGCGCGCGGAGCCGGGCGCCGAACCGGCGCGCGCCGTGTGAGCCCGCGCAGCCCATTGCTCCGC
GTCGCCGCGCGCCGCATCGA

Downstream 100 bases:

>100_bases
AGACACCGGCCGGATGATGCGGCCTGGTCGCTTCGACCGTCGTTGCGGCCGTCGCGCCGCTACGCCGGCGCACCGTCGGC
GATCGCCGAGCCGGCGATTC

Product: glutamyl-Q tRNA(Asp) synthetase

Products: NA

Alternate protein names: Glu-Q-RSs

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MTRYRGRFAPSPTGPLHFGSLVGALASWLDARAWGGAWLVRIEDIDGPRTVPGAAEDMLATLRGFGFIADEPPVWQSARV
AHYEAALARLTAAGLVYPCGCSRKEIADSLRAAHERHTTLAYPGTCRTGLHGKPARAWRLRVPDGAAAVVAFDDRWQRAQ
TQNLATEVGDFVLKRADGQWAYQLAVVVDDGDANITHVVRGADLLDSTARQIYLQRCLGLPTPRYLHVPVVLDANGEKLS
KQTGAAALDPAAPLPALAAAARHLGLALDGAACASLDAFQAAAIAAWDARFGPNARG

Sequences:

>Translated_297_residues
MTRYRGRFAPSPTGPLHFGSLVGALASWLDARAWGGAWLVRIEDIDGPRTVPGAAEDMLATLRGFGFIADEPPVWQSARV
AHYEAALARLTAAGLVYPCGCSRKEIADSLRAAHERHTTLAYPGTCRTGLHGKPARAWRLRVPDGAAAVVAFDDRWQRAQ
TQNLATEVGDFVLKRADGQWAYQLAVVVDDGDANITHVVRGADLLDSTARQIYLQRCLGLPTPRYLHVPVVLDANGEKLS
KQTGAAALDPAAPLPALAAAARHLGLALDGAACASLDAFQAAAIAAWDARFGPNARG
>Mature_296_residues
TRYRGRFAPSPTGPLHFGSLVGALASWLDARAWGGAWLVRIEDIDGPRTVPGAAEDMLATLRGFGFIADEPPVWQSARVA
HYEAALARLTAAGLVYPCGCSRKEIADSLRAAHERHTTLAYPGTCRTGLHGKPARAWRLRVPDGAAAVVAFDDRWQRAQT
QNLATEVGDFVLKRADGQWAYQLAVVVDDGDANITHVVRGADLLDSTARQIYLQRCLGLPTPRYLHVPVVLDANGEKLSK
QTGAAALDPAAPLPALAAAARHLGLALDGAACASLDAFQAAAIAAWDARFGPNARG

Specific function: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble positi

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily

Homologues:

Organism=Homo sapiens, GI134288884, Length=264, Percent_Identity=37.1212121212121, Blast_Score=150, Evalue=1e-36,
Organism=Escherichia coli, GI226510925, Length=264, Percent_Identity=45.8333333333333, Blast_Score=202, Evalue=1e-53,
Organism=Escherichia coli, GI1788743, Length=247, Percent_Identity=35.6275303643725, Blast_Score=158, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI71993394, Length=290, Percent_Identity=31.0344827586207, Blast_Score=129, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6324540, Length=259, Percent_Identity=33.2046332046332, Blast_Score=134, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24665321, Length=260, Percent_Identity=34.6153846153846, Blast_Score=129, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLUQ_BURMA (Q62IG0)

Other databases:

- EMBL:   CP000010
- RefSeq:   YP_103510.1
- ProteinModelPortal:   Q62IG0
- SMR:   Q62IG0
- GeneID:   3090853
- GenomeReviews:   CP000010_GR
- KEGG:   bma:BMA1915
- TIGR:   BMA1915
- HOGENOM:   HBG628189
- OMA:   IIKRSDG
- PhylomeDB:   Q62IG0
- ProtClustDB:   PRK05710
- BioCyc:   BMAL243160:BMA_1915-MONOMER
- GO:   GO:0005737
- GO:   GO:0006412
- HAMAP:   MF_01428
- InterPro:   IPR022380
- InterPro:   IPR000924
- InterPro:   IPR020058
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR10119
- PRINTS:   PR00987
- TIGRFAMs:   TIGR03838

Pfam domain/function: PF00749 tRNA-synt_1c

EC number: NA

Molecular weight: Translated: 31600; Mature: 31469

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 43-43 BINDING 182-182 BINDING 200-200 BINDING 241-241

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRYRGRFAPSPTGPLHFGSLVGALASWLDARAWGGAWLVRIEDIDGPRTVPGAAEDMLA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHHHHH
TLRGFGFIADEPPVWQSARVAHYEAALARLTAAGLVYPCGCSRKEIADSLRAAHERHTTL
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCEEECCCCCHHHHHHHHHHHHHHCCEE
AYPGTCRTGLHGKPARAWRLRVPDGAAAVVAFDDRWQRAQTQNLATEVGDFVLKRADGQW
ECCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCE
AYQLAVVVDDGDANITHVVRGADLLDSTARQIYLQRCLGLPTPRYLHVPVVLDANGEKLS
EEEEEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHH
KQTGAAALDPAAPLPALAAAARHLGLALDGAACASLDAFQAAAIAAWDARFGPNARG
HHCCCCCCCCCCCHHHHHHHHHHHCEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TRYRGRFAPSPTGPLHFGSLVGALASWLDARAWGGAWLVRIEDIDGPRTVPGAAEDMLA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHHHHH
TLRGFGFIADEPPVWQSARVAHYEAALARLTAAGLVYPCGCSRKEIADSLRAAHERHTTL
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCEEECCCCCHHHHHHHHHHHHHHCCEE
AYPGTCRTGLHGKPARAWRLRVPDGAAAVVAFDDRWQRAQTQNLATEVGDFVLKRADGQW
ECCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCE
AYQLAVVVDDGDANITHVVRGADLLDSTARQIYLQRCLGLPTPRYLHVPVVLDANGEKLS
EEEEEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHH
KQTGAAALDPAAPLPALAAAARHLGLALDGAACASLDAFQAAAIAAWDARFGPNARG
HHCCCCCCCCCCCHHHHHHHHHHHCEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA