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The map label for this gene is ephD [H]

Identifier: 53718701

GI number: 53718701

Start: 1229071

End: 1229997

Strand: Reverse

Name: ephD [H]

Synonym: BPSL1064

Alternate gene names: 53718701

Gene position: 1229997-1229071 (Counterclockwise)

Preceding gene: 53718702

Following gene: 53718694

Centisome position: 30.19

GC content: 65.05

Gene sequence:

>927_bases
ATGCACACGCCCGACCTCTTCGTTCAATCGAGCAACGTCCGCCTGGCGGTCTATACGTGGGGCGACAAGCCCAGTGCGGA
CAAGCCTCGCGACATCGTCGTGCTGGCGCATGGCTTTCCCGATCGCGCACTGTTCTGGGAGCAGGTCGCCGCCGCGTTGC
AACGCGATTTCTACGTCGTCGCCTACGACATGCGAGGCTGCGCCAATTCCACGCATATCAAGGGGGCCCGGCATTATCGG
TTCGCCTTGCTTCTCGCCGATCTCTACGCCGTCATCGACGCGGTTTCGGCAGGCCGGCCCGTGCACCTCGTCGGGCATGA
TTGGGGAGGCGTCTACGGCTGGGACGCGATCGCCGATCCGGAAGGCGCGCGCCGCATCGCGTCGCTCACCACGCTTTCGC
CGAGCCTGGATCAGATCGGCTTCTATCTGCGCCGCCGGTTGCTGCGCCCGACGCCGCGCCACCTCGCGCAGTTGGTCGGC
CAACTGATGCGCAACAGCCTAATGACCTTCTTCACGGCGCCATTGCTGCCGGAGCTGCTGTTCGCCAGCGGACTCGCCAT
GGCGATGTTCCGTCGAATCATCGCGCACTACGAGCCGCGCATCACGTTCCGGAAAAACGACGGCATGGAAGGCGACGCGA
TACGCTACCTCGGCATTTATCGGGCGAACCTGCTGCAACGCGTACTGCGCCCGAGGAAGCGCGTCAGTACGACGCCGGTA
CATGCGCTGATGGCGATTCACGATCCTTTCCTGCCTCCGGCGCTCTTCGAAGGCTGCCGCGAATTCACGACGCGATACAG
CGAATCGACCGTCGACGCCGCGCACTGGGCGCCCTTGAGCCGGCCGCAGGAAATCGCGGAAACGGTTGGCGCGTTCGTGC
GGCAAGCCAGCCGGCGCCCCGACGTCGCGCTGCAATCGGCAAGCTGA

Upstream 100 bases:

>100_bases
CGGTCGGCTTCAGCAGCAGCCTGCTTTTTCTGGCCGCTTTCCATGTGATCTTCGGCCAGGCAACCCGAGAGCACAACTAA
CCACTTCGGAGCGACCCGAC

Downstream 100 bases:

>100_bases
GAAGGAAGCGCCCGCGCGGCGACGCGTGGCGTGCTGCGCGAGCAGACGCAGGCACGCGACGCGACGCGCGTCGCTCGTTC
GATTCGCCTCGCGTAGCCGT

Product: putative dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MHTPDLFVQSSNVRLAVYTWGDKPSADKPRDIVVLAHGFPDRALFWEQVAAALQRDFYVVAYDMRGCANSTHIKGARHYR
FALLLADLYAVIDAVSAGRPVHLVGHDWGGVYGWDAIADPEGARRIASLTTLSPSLDQIGFYLRRRLLRPTPRHLAQLVG
QLMRNSLMTFFTAPLLPELLFASGLAMAMFRRIIAHYEPRITFRKNDGMEGDAIRYLGIYRANLLQRVLRPRKRVSTTPV
HALMAIHDPFLPPALFEGCREFTTRYSESTVDAAHWAPLSRPQEIAETVGAFVRQASRRPDVALQSAS

Sequences:

>Translated_308_residues
MHTPDLFVQSSNVRLAVYTWGDKPSADKPRDIVVLAHGFPDRALFWEQVAAALQRDFYVVAYDMRGCANSTHIKGARHYR
FALLLADLYAVIDAVSAGRPVHLVGHDWGGVYGWDAIADPEGARRIASLTTLSPSLDQIGFYLRRRLLRPTPRHLAQLVG
QLMRNSLMTFFTAPLLPELLFASGLAMAMFRRIIAHYEPRITFRKNDGMEGDAIRYLGIYRANLLQRVLRPRKRVSTTPV
HALMAIHDPFLPPALFEGCREFTTRYSESTVDAAHWAPLSRPQEIAETVGAFVRQASRRPDVALQSAS
>Mature_308_residues
MHTPDLFVQSSNVRLAVYTWGDKPSADKPRDIVVLAHGFPDRALFWEQVAAALQRDFYVVAYDMRGCANSTHIKGARHYR
FALLLADLYAVIDAVSAGRPVHLVGHDWGGVYGWDAIADPEGARRIASLTTLSPSLDQIGFYLRRRLLRPTPRHLAQLVG
QLMRNSLMTFFTAPLLPELLFASGLAMAMFRRIIAHYEPRITFRKNDGMEGDAIRYLGIYRANLLQRVLRPRKRVSTTPV
HALMAIHDPFLPPALFEGCREFTTRYSESTVDAAHWAPLSRPQEIAETVGAFVRQASRRPDVALQSAS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI218777837, Length=296, Percent_Identity=22.2972972972973, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI218777840, Length=302, Percent_Identity=26.158940397351, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI13376164, Length=302, Percent_Identity=26.158940397351, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF00106 adh_short [H]

EC number: NA

Molecular weight: Translated: 34637; Mature: 34637

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTPDLFVQSSNVRLAVYTWGDKPSADKPRDIVVLAHGFPDRALFWEQVAAALQRDFYVV
CCCCCCEEECCCCEEEEEECCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCEEE
AYDMRGCANSTHIKGARHYRFALLLADLYAVIDAVSAGRPVHLVGHDWGGVYGWDAIADP
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCC
EGARRIASLTTLSPSLDQIGFYLRRRLLRPTPRHLAQLVGQLMRNSLMTFFTAPLLPELL
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FASGLAMAMFRRIIAHYEPRITFRKNDGMEGDAIRYLGIYRANLLQRVLRPRKRVSTTPV
HHCCHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHH
HALMAIHDPFLPPALFEGCREFTTRYSESTVDAAHWAPLSRPQEIAETVGAFVRQASRRP
HHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCC
DVALQSAS
CCEECCCC
>Mature Secondary Structure
MHTPDLFVQSSNVRLAVYTWGDKPSADKPRDIVVLAHGFPDRALFWEQVAAALQRDFYVV
CCCCCCEEECCCCEEEEEECCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCEEE
AYDMRGCANSTHIKGARHYRFALLLADLYAVIDAVSAGRPVHLVGHDWGGVYGWDAIADP
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCC
EGARRIASLTTLSPSLDQIGFYLRRRLLRPTPRHLAQLVGQLMRNSLMTFFTAPLLPELL
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FASGLAMAMFRRIIAHYEPRITFRKNDGMEGDAIRYLGIYRANLLQRVLRPRKRVSTTPV
HHCCHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHH
HALMAIHDPFLPPALFEGCREFTTRYSESTVDAAHWAPLSRPQEIAETVGAFVRQASRRP
HHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCC
DVALQSAS
CCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]