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The map label for this gene is pbpG [H]

Identifier: 53718694

GI number: 53718694

Start: 1222714

End: 1223850

Strand: Reverse

Name: pbpG [H]

Synonym: BPSL1055

Alternate gene names: 53718694

Gene position: 1223850-1222714 (Counterclockwise)

Preceding gene: 53718701

Following gene: 53718692

Centisome position: 30.04

GC content: 69.92

Gene sequence:

>1137_bases
ATGCCATCCACGCCGCATCACCCAAGCCGCCTCCCCGTCCGTCTGCTGTTCGCCGTCTGCATCGTCTGGATCGCGTCCGT
TCTGGGCGTCGGATTCGCGTCGCCCGCTCACGCGGCGGGCAAGGCCTGCGCACGCACATCGGCTGCGCACGGCCACGCGT
GTCGCAGCGCGCGCGCCGCGCATGCGAAACACGCCCAGCGCGCCGCTCGCGCGCGGCATCATGCGCCGCACGCGAAACCC
AAACGCGCGGCCATACCGGGAAAGGCCGGACATCGCGCGCGCACGGCCGCGCATCGGCATCATCCGAAGCGCAAGCGGCC
GCGCGCGGCGCGCGATACCGTCGTCGCGGCCGCGAAGCCGCAACTGCTCGCGCGCTGCGGCTACACCGCCGCGTCGCGCC
ACCTGCTGCGCTCACGCGCGATCTACGTCGTCGATGAGCGCACGGGTACGGTGTTGATCGAAAGAAACGCAAATCGCGTC
ATGCCGATCGCGTCGGTCACCAAGCTGATGACGTCGATGGTCGCGCTCGATACGCGCGCGCCGATGTCGCGCCCGCTGCG
CGTAAGCGCGCAGGACCGCGACTACGAAAAATTCACGGGATCGCGCCTGAAGGTCGGCTCGGTGCTGTCGCGCCGCGACA
TGCTGCACATCGCGCTGATGTCGTCGGAAAACCGCGCGGCGGCGGCGCTCTCGCGCGACTATCCGGGCGGCCGGCCCGCG
TTCGTCGCCGCGATGAACCGCAAGGCGCGCACGCTCGGCATGAAGCGCACGCACTTCGTCAACGCGACCGGGCTGTCGCC
GCGCAACGTATCGACAGCGCGCGACCTGTCGCGGCTCGTCGCCGCGGCAAGCCGCTATCCGCGCATCAAGACGTTCTCGA
CCGCGACGTCGAAGACGGTCTTCCCCGGCCGCGGCCAGTTGCGCTATGTGAATTCGGACGCGCTCGTGCGCGCCGGCGAT
TCGAGCATCGTGTTGCAGAAAACGGGCTTCATCAACGAAGCGGGCCACTGCGTGGTGCTGCGCTACGCGGTGCGCGGGCG
GCCGGTCGACATCGTGCTGCTCGGCGCGCCGGGGCCGCACGACCATGTTGCCGATGCGGCGAAGATCCGCCGCTGGCTCA
CGTGCTCGATGCAGTGA

Upstream 100 bases:

>100_bases
ACACCATCAATATCGCCGTCGCCGAGAATTTCCCGACCGCTCCGCGGTCCTATCGCGCGACACGCTCGTTCGACTCTCTC
CCGCTTCCTGTCCGATCGCC

Downstream 100 bases:

>100_bases
CGCCGCAGCAGCGCAACCGCCGTCGGGGCGCCGGCGCGATCCGCGCGCGGCACGTCGCGCCGCGACCGCCGCGGATCGCA
GCGAGCCGCCGCGCCGCTTA

Product: murein-DD-endopeptidase

Products: NA

Alternate protein names: DD-endopeptidase; Penicillin-binding protein 5; PBP-5 [H]

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MPSTPHHPSRLPVRLLFAVCIVWIASVLGVGFASPAHAAGKACARTSAAHGHACRSARAAHAKHAQRAARARHHAPHAKP
KRAAIPGKAGHRARTAAHRHHPKRKRPRAARDTVVAAAKPQLLARCGYTAASRHLLRSRAIYVVDERTGTVLIERNANRV
MPIASVTKLMTSMVALDTRAPMSRPLRVSAQDRDYEKFTGSRLKVGSVLSRRDMLHIALMSSENRAAAALSRDYPGGRPA
FVAAMNRKARTLGMKRTHFVNATGLSPRNVSTARDLSRLVAAASRYPRIKTFSTATSKTVFPGRGQLRYVNSDALVRAGD
SSIVLQKTGFINEAGHCVVLRYAVRGRPVDIVLLGAPGPHDHVADAAKIRRWLTCSMQ

Sequences:

>Translated_378_residues
MPSTPHHPSRLPVRLLFAVCIVWIASVLGVGFASPAHAAGKACARTSAAHGHACRSARAAHAKHAQRAARARHHAPHAKP
KRAAIPGKAGHRARTAAHRHHPKRKRPRAARDTVVAAAKPQLLARCGYTAASRHLLRSRAIYVVDERTGTVLIERNANRV
MPIASVTKLMTSMVALDTRAPMSRPLRVSAQDRDYEKFTGSRLKVGSVLSRRDMLHIALMSSENRAAAALSRDYPGGRPA
FVAAMNRKARTLGMKRTHFVNATGLSPRNVSTARDLSRLVAAASRYPRIKTFSTATSKTVFPGRGQLRYVNSDALVRAGD
SSIVLQKTGFINEAGHCVVLRYAVRGRPVDIVLLGAPGPHDHVADAAKIRRWLTCSMQ
>Mature_377_residues
PSTPHHPSRLPVRLLFAVCIVWIASVLGVGFASPAHAAGKACARTSAAHGHACRSARAAHAKHAQRAARARHHAPHAKPK
RAAIPGKAGHRARTAAHRHHPKRKRPRAARDTVVAAAKPQLLARCGYTAASRHLLRSRAIYVVDERTGTVLIERNANRVM
PIASVTKLMTSMVALDTRAPMSRPLRVSAQDRDYEKFTGSRLKVGSVLSRRDMLHIALMSSENRAAAALSRDYPGGRPAF
VAAMNRKARTLGMKRTHFVNATGLSPRNVSTARDLSRLVAAASRYPRIKTFSTATSKTVFPGRGQLRYVNSDALVRAGDS
SIVLQKTGFINEAGHCVVLRYAVRGRPVDIVLLGAPGPHDHVADAAKIRRWLTCSMQ

Specific function: Cell wall formation [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI87082054, Length=233, Percent_Identity=45.9227467811159, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI87082022, Length=241, Percent_Identity=29.8755186721992, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR018044
- InterPro:   IPR001967 [H]

Pfam domain/function: PF00768 Peptidase_S11 [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 41042; Mature: 40911

Theoretical pI: Translated: 12.25; Mature: 12.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSTPHHPSRLPVRLLFAVCIVWIASVLGVGFASPAHAAGKACARTSAAHGHACRSARAA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHH
HAKHAQRAARARHHAPHAKPKRAAIPGKAGHRARTAAHRHHPKRKRPRAARDTVVAAAKP
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHEEECCCH
QLLARCGYTAASRHLLRSRAIYVVDERTGTVLIERNANRVMPIASVTKLMTSMVALDTRA
HHHHHCCCHHHHHHHHHCCEEEEEECCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHCCC
PMSRPLRVSAQDRDYEKFTGSRLKVGSVLSRRDMLHIALMSSENRAAAALSRDYPGGRPA
CCCCCEEECCCCCCHHHHCCCCEEHHHHHHHCCEEEEEEECCCCHHHHHHHCCCCCCCCC
FVAAMNRKARTLGMKRTHFVNATGLSPRNVSTARDLSRLVAAASRYPRIKTFSTATSKTV
EEEECCCHHHHHCCCHHEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCEE
FPGRGQLRYVNSDALVRAGDSSIVLQKTGFINEAGHCVVLRYAVRGRPVDIVLLGAPGPH
CCCCCCEEEECCCCEEEECCCEEEEEECCCCCCCCCEEEEEEECCCCCEEEEEECCCCCC
DHVADAAKIRRWLTCSMQ
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PSTPHHPSRLPVRLLFAVCIVWIASVLGVGFASPAHAAGKACARTSAAHGHACRSARAA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHH
HAKHAQRAARARHHAPHAKPKRAAIPGKAGHRARTAAHRHHPKRKRPRAARDTVVAAAKP
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHEEECCCH
QLLARCGYTAASRHLLRSRAIYVVDERTGTVLIERNANRVMPIASVTKLMTSMVALDTRA
HHHHHCCCHHHHHHHHHCCEEEEEECCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHCCC
PMSRPLRVSAQDRDYEKFTGSRLKVGSVLSRRDMLHIALMSSENRAAAALSRDYPGGRPA
CCCCCEEECCCCCCHHHHCCCCEEHHHHHHHCCEEEEEEECCCCHHHHHHHCCCCCCCCC
FVAAMNRKARTLGMKRTHFVNATGLSPRNVSTARDLSRLVAAASRYPRIKTFSTATSKTV
EEEECCCHHHHHCCCHHEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCEE
FPGRGQLRYVNSDALVRAGDSSIVLQKTGFINEAGHCVVLRYAVRGRPVDIVLLGAPGPH
CCCCCCEEEECCCCEEEECCCEEEEEECCCCCCCCCEEEEEEECCCCCEEEEEECCCCCC
DHVADAAKIRRWLTCSMQ
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]