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The map label for this gene is argD [H]

Identifier: 53718568

GI number: 53718568

Start: 1078621

End: 1079805

Strand: Reverse

Name: argD [H]

Synonym: BPSL0926

Alternate gene names: 53718568

Gene position: 1079805-1078621 (Counterclockwise)

Preceding gene: 53718569

Following gene: 53718567

Centisome position: 26.5

GC content: 66.75

Gene sequence:

>1185_bases
ATGCCGCTGAACGACTACCCGATCGACTCGCTGATGTACATCACGAACCGCCCCGACATCGTGTTCACGCACGGCAAGGG
CTCGTGGCTCTACGACCACACCGGCAAGCGCTACCTGGATTTCATCCAGGGCTGGGCGGTCAACTGCCTCGGCCACTGCA
ACGAAGGCCTCGTCCAGGCGCTGCAGGCGCAGGCCGAGAAGCTGCTGAACCCGTCGCCCGCGTTCTACAACGAGCCGATG
GCGAAGCTCGCCGGCCTCCTCACGCAGCACAGCGTGTTCGACAAGGTGTTCTTCGCGAACAGCGGCGCGGAAGCGAATGA
AGGCGCGATCAAGCTCGCGCGCAAATGGGGGCGCAAGTTCAGGAACGGCGCGTACGAGATCATCACGTTCGACCACAGCT
TCCACGGCCGCACGCTCGCGACGATGTCGGCGAGCGGCAAGGCCGGCTGGGACACGATCTACGCGCCGCAGGTGCCGGGC
TTCCCGAAGGCCGAGATCAACGATATCAATTCGGTCGAGCGGCTGATCAACGACAAGACCGTTGCCGTGATGCTCGAGCC
GATCCAGGGCGAAGGCGGCGTGATCCCGGCGACGCGCGAATTCATGCAGCAGTTGCGCGCACTGACGAAGCAGCACGACC
TGCTGCTCATCGTCGACGAAGTGCAAAGCGGCTGCGGTCGCGCCGGCACGCTGTTCGCGTACGAGCTCGCCGGCGTCGAG
CCGGACATCATGACGCTCGGCAAGGGCATCGGCGGCGGCGTGCCGCTCGCGGCGCTGCTGTCGAAGGCCGACGTCGCGGT
GTTCGAGGCGGGCGACCAGGGCGGCACCTACAACGGCAACCCGCTGATGAGCGCGGCGGGGCACGCGGTGATCTCGCAAC
TCGTCGCGCCGGGCTTCCTGGAGGGCGTGCGCGCGCGCGGCGAGTACCTGAAGCACAAGCTGCTCGAACTGTCGGAGGAG
CGCGGCTTCGAGGGCGAGCGCGGCGAAGGCCTGTTGCGCGCGCTCCTGCTCGGCAAGGACATCGGCCCGCAGATCGTCGA
GAAGGCGCGCGACATGCAGCCGGACGGCCTGCTGCTGAACGCCGCGCGCCCGAACCTGCTGCGCTTCATGCCGGCGCTGA
ACGTGACGAACGACGAGATCGACCAGATGATGGCGATGCTGCGTTCGGTGCTCGATTCGCTCTGA

Upstream 100 bases:

>100_bases
CGCTTCCCCGTTACGCAAAAGCTGTTCGAACCATCAAGCCACGGCGCCCCGTGGCTTTTTTTATTGTCCTTTCGCCGACC
GCCCGCTGGAGCCTGCCGCT

Downstream 100 bases:

>100_bases
TCGCATGTCCGCCGGCATGTCGACGGCGATCGTCTCGGACGACATCGCGATCCGCCCGTTCGCGCGCGCCGACACCGACG
CCGCACTCGCCGTGTGGCGC

Product: acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MPLNDYPIDSLMYITNRPDIVFTHGKGSWLYDHTGKRYLDFIQGWAVNCLGHCNEGLVQALQAQAEKLLNPSPAFYNEPM
AKLAGLLTQHSVFDKVFFANSGAEANEGAIKLARKWGRKFRNGAYEIITFDHSFHGRTLATMSASGKAGWDTIYAPQVPG
FPKAEINDINSVERLINDKTVAVMLEPIQGEGGVIPATREFMQQLRALTKQHDLLLIVDEVQSGCGRAGTLFAYELAGVE
PDIMTLGKGIGGGVPLAALLSKADVAVFEAGDQGGTYNGNPLMSAAGHAVISQLVAPGFLEGVRARGEYLKHKLLELSEE
RGFEGERGEGLLRALLLGKDIGPQIVEKARDMQPDGLLLNAARPNLLRFMPALNVTNDEIDQMMAMLRSVLDSL

Sequences:

>Translated_394_residues
MPLNDYPIDSLMYITNRPDIVFTHGKGSWLYDHTGKRYLDFIQGWAVNCLGHCNEGLVQALQAQAEKLLNPSPAFYNEPM
AKLAGLLTQHSVFDKVFFANSGAEANEGAIKLARKWGRKFRNGAYEIITFDHSFHGRTLATMSASGKAGWDTIYAPQVPG
FPKAEINDINSVERLINDKTVAVMLEPIQGEGGVIPATREFMQQLRALTKQHDLLLIVDEVQSGCGRAGTLFAYELAGVE
PDIMTLGKGIGGGVPLAALLSKADVAVFEAGDQGGTYNGNPLMSAAGHAVISQLVAPGFLEGVRARGEYLKHKLLELSEE
RGFEGERGEGLLRALLLGKDIGPQIVEKARDMQPDGLLLNAARPNLLRFMPALNVTNDEIDQMMAMLRSVLDSL
>Mature_393_residues
PLNDYPIDSLMYITNRPDIVFTHGKGSWLYDHTGKRYLDFIQGWAVNCLGHCNEGLVQALQAQAEKLLNPSPAFYNEPMA
KLAGLLTQHSVFDKVFFANSGAEANEGAIKLARKWGRKFRNGAYEIITFDHSFHGRTLATMSASGKAGWDTIYAPQVPGF
PKAEINDINSVERLINDKTVAVMLEPIQGEGGVIPATREFMQQLRALTKQHDLLLIVDEVQSGCGRAGTLFAYELAGVEP
DIMTLGKGIGGGVPLAALLSKADVAVFEAGDQGGTYNGNPLMSAAGHAVISQLVAPGFLEGVRARGEYLKHKLLELSEER
GFEGERGEGLLRALLLGKDIGPQIVEKARDMQPDGLLLNAARPNLLRFMPALNVTNDEIDQMMAMLRSVLDSL

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=381, Percent_Identity=32.2834645669291, Blast_Score=206, Evalue=3e-53,
Organism=Homo sapiens, GI284507298, Length=301, Percent_Identity=32.2259136212625, Blast_Score=155, Evalue=9e-38,
Organism=Homo sapiens, GI13994255, Length=427, Percent_Identity=28.1030444964871, Blast_Score=145, Evalue=7e-35,
Organism=Homo sapiens, GI24119277, Length=416, Percent_Identity=27.8846153846154, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI37574042, Length=416, Percent_Identity=28.125, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI226442705, Length=416, Percent_Identity=27.1634615384615, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI226442709, Length=386, Percent_Identity=28.2383419689119, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI188536080, Length=429, Percent_Identity=23.5431235431235, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI38679950, Length=429, Percent_Identity=23.5431235431235, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI38679946, Length=429, Percent_Identity=23.5431235431235, Blast_Score=83, Evalue=4e-16,
Organism=Escherichia coli, GI1788044, Length=384, Percent_Identity=42.4479166666667, Blast_Score=287, Evalue=8e-79,
Organism=Escherichia coli, GI1789759, Length=369, Percent_Identity=41.7344173441734, Blast_Score=270, Evalue=1e-73,
Organism=Escherichia coli, GI1789016, Length=396, Percent_Identity=34.0909090909091, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI145693181, Length=391, Percent_Identity=30.9462915601023, Blast_Score=161, Evalue=6e-41,
Organism=Escherichia coli, GI1787560, Length=398, Percent_Identity=31.9095477386935, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1786349, Length=332, Percent_Identity=32.8313253012048, Blast_Score=141, Evalue=9e-35,
Organism=Escherichia coli, GI1786991, Length=315, Percent_Identity=29.5238095238095, Blast_Score=100, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI25144271, Length=380, Percent_Identity=33.1578947368421, Blast_Score=212, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI32564660, Length=417, Percent_Identity=28.0575539568345, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI25144274, Length=270, Percent_Identity=33.3333333333333, Blast_Score=144, Evalue=9e-35,
Organism=Caenorhabditis elegans, GI71992977, Length=416, Percent_Identity=27.8846153846154, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71981843, Length=159, Percent_Identity=31.4465408805031, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17541228, Length=426, Percent_Identity=24.8826291079812, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6324432, Length=401, Percent_Identity=32.9177057356608, Blast_Score=206, Evalue=4e-54,
Organism=Saccharomyces cerevisiae, GI6323470, Length=397, Percent_Identity=31.7380352644836, Blast_Score=186, Evalue=6e-48,
Organism=Saccharomyces cerevisiae, GI6321456, Length=424, Percent_Identity=25.2358490566038, Blast_Score=97, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6324386, Length=462, Percent_Identity=25.5411255411255, Blast_Score=83, Evalue=8e-17,
Organism=Drosophila melanogaster, GI21357415, Length=381, Percent_Identity=33.3333333333333, Blast_Score=212, Evalue=4e-55,
Organism=Drosophila melanogaster, GI28574759, Length=410, Percent_Identity=28.0487804878049, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI161085790, Length=415, Percent_Identity=27.4698795180723, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI21356575, Length=426, Percent_Identity=26.5258215962441, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI281366494, Length=426, Percent_Identity=24.4131455399061, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24667139, Length=426, Percent_Identity=24.4131455399061, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24667143, Length=426, Percent_Identity=24.4131455399061, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 42893; Mature: 42762

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLNDYPIDSLMYITNRPDIVFTHGKGSWLYDHTGKRYLDFIQGWAVNCLGHCNEGLVQA
CCCCCCCCCCEEEEECCCCEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHH
LQAQAEKLLNPSPAFYNEPMAKLAGLLTQHSVFDKVFFANSGAEANEGAIKLARKWGRKF
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
RNGAYEIITFDHSFHGRTLATMSASGKAGWDTIYAPQVPGFPKAEINDINSVERLINDKT
CCCCEEEEEECCCCCCCEEEEECCCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHCCCE
VAVMLEPIQGEGGVIPATREFMQQLRALTKQHDLLLIVDEVQSGCGRAGTLFAYELAGVE
EEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEEHHHHCCCCCCCCEEEEEECCCC
PDIMTLGKGIGGGVPLAALLSKADVAVFEAGDQGGTYNGNPLMSAAGHAVISQLVAPGFL
HHHHHHCCCCCCCHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCHHH
EGVRARGEYLKHKLLELSEERGFEGERGEGLLRALLLGKDIGPQIVEKARDMQPDGLLLN
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEE
AARPNLLRFMPALNVTNDEIDQMMAMLRSVLDSL
CCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PLNDYPIDSLMYITNRPDIVFTHGKGSWLYDHTGKRYLDFIQGWAVNCLGHCNEGLVQA
CCCCCCCCCEEEEECCCCEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHH
LQAQAEKLLNPSPAFYNEPMAKLAGLLTQHSVFDKVFFANSGAEANEGAIKLARKWGRKF
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
RNGAYEIITFDHSFHGRTLATMSASGKAGWDTIYAPQVPGFPKAEINDINSVERLINDKT
CCCCEEEEEECCCCCCCEEEEECCCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHCCCE
VAVMLEPIQGEGGVIPATREFMQQLRALTKQHDLLLIVDEVQSGCGRAGTLFAYELAGVE
EEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEEHHHHCCCCCCCCEEEEEECCCC
PDIMTLGKGIGGGVPLAALLSKADVAVFEAGDQGGTYNGNPLMSAAGHAVISQLVAPGFL
HHHHHHCCCCCCCHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCHHH
EGVRARGEYLKHKLLELSEERGFEGERGEGLLRALLLGKDIGPQIVEKARDMQPDGLLLN
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEE
AARPNLLRFMPALNVTNDEIDQMMAMLRSVLDSL
CCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]