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The map label for this gene is lpxK [H]

Identifier: 53718517

GI number: 53718517

Start: 1017431

End: 1018459

Strand: Reverse

Name: lpxK [H]

Synonym: BPSL0878

Alternate gene names: 53718517

Gene position: 1018459-1017431 (Counterclockwise)

Preceding gene: 53718521

Following gene: 53718516

Centisome position: 25.0

GC content: 73.76

Gene sequence:

>1029_bases
ATGAGCGCTCGGCCGGGATTGCTCGCACGCGCCGAAGCGCGCCTCACCCGCGAGTGGCAGCGCCGCGGCGCGCTCGCATG
GGCGCTCGCGCCGTTCGCCTGCGCGTTCGGCGCGATCGCCGCGCTGCGCCGCGCCGCCTATGCGCGCGGCTGGAAGGCGC
GCGTCGATTGCGGCGTGCCCGTCGTCGTCGTCGGCAATGTGACGGTCGGCGGCACCGGCAAGACGCCCACCGTGATCGCG
CTCGTCGACGCGCTGCGCGCCGCGGGCTTCACGCCCGGCGTCGTATCGCGCGGCTACGGCGCGAAGATCGCCGCGCCGAC
CGCGGTCACGGCCGCGTCGCCGCCGCAGCAGGCGGGCGACGAGCCGCTCCTGATCGCGCGCCGCACGCTCGCGCCCGTGT
GGGTGTGCCCGGACCGCGTCGCGGCCGTGCGCGCGCTGAAGGCCGCGCACCCCGAAGTGGACGTCGTCGTCAGCGACGAC
GGCCTGCAGCACTACCGGCTCGCGCGCGCGGTCGAGATCGTCGTGTTCGACCATCGCCTCGGCGGCAACGGCTTTCTGCT
GCCGGCCGGGCCGCTGCGCGAGCCGTTGTCGCGCCGGCGCGACGCGACGCTCGTCAACGATCCGTACAGCCGCGCGCTGC
CGCCGTGGCCCGATACGTTCGCGCTGTCGCTCGCGCCCGGCGACGCCTGGCATCTCGATCGACCGTCGCGGCGCAAGCCG
CTCGCGCAATTCGCGGGCGAGCGCGTGCTCGCGGCCGCAGGCATCGGCGCGCCCGAGCGCTTTTTCGCGACGCTGCGCGC
GGCGGGCGTCGCGCCCGCGACGCGCGCGCTGCCCGATCACTACGCGTTCGCGACGAACCCGTTCGTCGACGATCATTTCG
ACGCGATCCTGATCACCGAGAAGGATGCAGTAAAATTGGGGACTTCGTGGCGCGACGCCCGCATCTGGGTCGTCCCGGTC
GAAGCCGCGCTCGATCCCCGCCTCATCGCTCTCGTTGTGGAGAAACTCCGTGGACGCACGTCTGCTTGA

Upstream 100 bases:

>100_bases
GCCGCCTTTCGAAGACCGCGCGGCCGCCCGCCGCCATCCGGAGAACCGTGTTGACGAATCCGTCCTCAATCGCGCCGCGC
GGCGTCCCGCGCATCGCGTC

Downstream 100 bases:

>100_bases
AATCCTCGTCTGCCCGATTTGCAAGGGTCCGCTCCACTATGATCGCGGCGCGCAGGAGCTCGTCTGCCATGCCGACAAGC
TCGCGTATCCGATTCGCGAC

Product: tetraacyldisaccharide 4'-kinase

Products: NA

Alternate protein names: Lipid A 4'-kinase [H]

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MSARPGLLARAEARLTREWQRRGALAWALAPFACAFGAIAALRRAAYARGWKARVDCGVPVVVVGNVTVGGTGKTPTVIA
LVDALRAAGFTPGVVSRGYGAKIAAPTAVTAASPPQQAGDEPLLIARRTLAPVWVCPDRVAAVRALKAAHPEVDVVVSDD
GLQHYRLARAVEIVVFDHRLGGNGFLLPAGPLREPLSRRRDATLVNDPYSRALPPWPDTFALSLAPGDAWHLDRPSRRKP
LAQFAGERVLAAAGIGAPERFFATLRAAGVAPATRALPDHYAFATNPFVDDHFDAILITEKDAVKLGTSWRDARIWVVPV
EAALDPRLIALVVEKLRGRTSA

Sequences:

>Translated_342_residues
MSARPGLLARAEARLTREWQRRGALAWALAPFACAFGAIAALRRAAYARGWKARVDCGVPVVVVGNVTVGGTGKTPTVIA
LVDALRAAGFTPGVVSRGYGAKIAAPTAVTAASPPQQAGDEPLLIARRTLAPVWVCPDRVAAVRALKAAHPEVDVVVSDD
GLQHYRLARAVEIVVFDHRLGGNGFLLPAGPLREPLSRRRDATLVNDPYSRALPPWPDTFALSLAPGDAWHLDRPSRRKP
LAQFAGERVLAAAGIGAPERFFATLRAAGVAPATRALPDHYAFATNPFVDDHFDAILITEKDAVKLGTSWRDARIWVVPV
EAALDPRLIALVVEKLRGRTSA
>Mature_341_residues
SARPGLLARAEARLTREWQRRGALAWALAPFACAFGAIAALRRAAYARGWKARVDCGVPVVVVGNVTVGGTGKTPTVIAL
VDALRAAGFTPGVVSRGYGAKIAAPTAVTAASPPQQAGDEPLLIARRTLAPVWVCPDRVAAVRALKAAHPEVDVVVSDDG
LQHYRLARAVEIVVFDHRLGGNGFLLPAGPLREPLSRRRDATLVNDPYSRALPPWPDTFALSLAPGDAWHLDRPSRRKPL
AQFAGERVLAAAGIGAPERFFATLRAAGVAPATRALPDHYAFATNPFVDDHFDAILITEKDAVKLGTSWRDARIWVVPVE
AALDPRLIALVVEKLRGRTSA

Specific function: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) [H]

COG id: COG1663

COG function: function code M; Tetraacyldisaccharide-1-P 4'-kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxK family [H]

Homologues:

Organism=Escherichia coli, GI1787144, Length=323, Percent_Identity=44.2724458204334, Blast_Score=203, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003758 [H]

Pfam domain/function: PF02606 LpxK [H]

EC number: =2.7.1.130 [H]

Molecular weight: Translated: 36511; Mature: 36380

Theoretical pI: Translated: 10.82; Mature: 10.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARPGLLARAEARLTREWQRRGALAWALAPFACAFGAIAALRRAAYARGWKARVDCGVP
CCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCC
VVVVGNVTVGGTGKTPTVIALVDALRAAGFTPGVVSRGYGAKIAAPTAVTAASPPQQAGD
EEEEECEEECCCCCCCHHHHHHHHHHHCCCCCHHHCCCCCCEECCCCEEECCCCHHHCCC
EPLLIARRTLAPVWVCPDRVAAVRALKAAHPEVDVVVSDDGLQHYRLARAVEIVVFDHRL
CCEEEEHHHCCCEEECCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHEEEEEEEEEEE
GGNGFLLPAGPLREPLSRRRDATLVNDPYSRALPPWPDTFALSLAPGDAWHLDRPSRRKP
CCCEEEECCCHHHHHHHHHCCCCEECCCHHHCCCCCCCCEEEEECCCCCCCCCCCHHCCH
LAQFAGERVLAAAGIGAPERFFATLRAAGVAPATRALPDHYAFATNPFVDDHFDAILITE
HHHHCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHCCCCCCEECCCCCCCCCCCEEEEEC
KDAVKLGTSWRDARIWVVPVEAALDPRLIALVVEKLRGRTSA
CCCEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SARPGLLARAEARLTREWQRRGALAWALAPFACAFGAIAALRRAAYARGWKARVDCGVP
CCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCC
VVVVGNVTVGGTGKTPTVIALVDALRAAGFTPGVVSRGYGAKIAAPTAVTAASPPQQAGD
EEEEECEEECCCCCCCHHHHHHHHHHHCCCCCHHHCCCCCCEECCCCEEECCCCHHHCCC
EPLLIARRTLAPVWVCPDRVAAVRALKAAHPEVDVVVSDDGLQHYRLARAVEIVVFDHRL
CCEEEEHHHCCCEEECCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHEEEEEEEEEEE
GGNGFLLPAGPLREPLSRRRDATLVNDPYSRALPPWPDTFALSLAPGDAWHLDRPSRRKP
CCCEEEECCCHHHHHHHHHCCCCEECCCHHHCCCCCCCCEEEEECCCCCCCCCCCHHCCH
LAQFAGERVLAAAGIGAPERFFATLRAAGVAPATRALPDHYAFATNPFVDDHFDAILITE
HHHHCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHCCCCCCEECCCCCCCCCCCEEEEEC
KDAVKLGTSWRDARIWVVPVEAALDPRLIALVVEKLRGRTSA
CCCEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA