Click here to switch to the map view.

The map label for this gene is psaA [H]

Identifier: 53718462

GI number: 53718462

Start: 958008

End: 958883

Strand: Reverse

Name: psaA [H]

Synonym: BPSL0824

Alternate gene names: 53718462

Gene position: 958883-958008 (Counterclockwise)

Preceding gene: 53718463

Following gene: 53718461

Centisome position: 23.53

GC content: 69.98

Gene sequence:

>876_bases
TTGCGCGCGGCGCGCGCGCTCGCCGCCGGCGTCGCGGCGCTCGCGCTCGCGAGCGCCGCGTTCGCGCAGAACGCGACACT
CAAAATCGTCGCCGCCGAGAATTTCTACGGCGACGTCGCCAAGCAGATCGGCGGGGCGCGCGTCGCCGTGTCGAGCGTCC
TCAGCAATCCCGATCAGGATCCGCATCTGTTCGAGGCGAGCCCGAAGGTCGCGCGCGAACTGCAGCACGCGGATCTCGTG
ATCTACAACGGCGCCGATTACGATCCGTGGATGGCGAAGCTCCTCGCCGCGTCGAAGAACGCGAAGCGCGCGACCGTGGT
CGTCGCCGAGCTCGTCGGCAAGAAGGCGGGCGACAATCCGCACCTGTGGTACGACCCGGCGACGATGCCCGCCGCGGCGC
GCGCGCTCGCCGCGGCGCTCGGCTCGGCCGACCCCGCGCACAAGGCCGAGTACGACGCGAACCTCGCGAAGTTCGTCGCG
TCGATGAAGCCGATCGACGCGAAGGTGGCCGGGCTGCGCGCGCGCTACAAGGGCGTGCCCGTGACCGCGACGGAGCCCGT
GTTCGGCTACATGGCCGACGCGATCGGGCTCGATATGCGCAACCCGCGCTTCCAGCTCGCGACGATGAACAACACCGAGG
CGAGCCCCGCCGACATCGCCGCGTTCGAGAACGACCTGAAACGGCGCCAGGTGCGCGTGCTGATCTACAACAGCCAGGCC
GTCGAGCCGATGACCAAGCGCATGCTCAAGCTCGCGCAGGACGCGCGCGTGCCGACCGTGAGCGTCACGGAAACGCAGCC
CGCCGGCAAGACCTTCCAGCAATGGATGCTCGCGCAGCTCGACGCGCTCGGCGCCGCGCTCGGCAAGCGCCCGTAA

Upstream 100 bases:

>100_bases
CACGCCGTCAACCCAATCGAGGATCGATCGCATGTCCCTTGCCGCTGCGCCACGCATGTTTGCCTCTTGTTCGTCGCGCT
CGCCGAGCGCGTCGCCGCTG

Downstream 100 bases:

>100_bases
CGACGTTCGCGACGGCCACGACATGACCCACCCCATGCATGCGCTCGAGCTCGATCACGTGACGCTCGCGCTCGGCGGCC
GCACGATCCTGCGCGACGTG

Product: putative periplasmic solute-binding protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: Pneumococcal surface adhesin A [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MRAARALAAGVAALALASAAFAQNATLKIVAAENFYGDVAKQIGGARVAVSSVLSNPDQDPHLFEASPKVARELQHADLV
IYNGADYDPWMAKLLAASKNAKRATVVVAELVGKKAGDNPHLWYDPATMPAAARALAAALGSADPAHKAEYDANLAKFVA
SMKPIDAKVAGLRARYKGVPVTATEPVFGYMADAIGLDMRNPRFQLATMNNTEASPADIAAFENDLKRRQVRVLIYNSQA
VEPMTKRMLKLAQDARVPTVSVTETQPAGKTFQQWMLAQLDALGAALGKRP

Sequences:

>Translated_291_residues
MRAARALAAGVAALALASAAFAQNATLKIVAAENFYGDVAKQIGGARVAVSSVLSNPDQDPHLFEASPKVARELQHADLV
IYNGADYDPWMAKLLAASKNAKRATVVVAELVGKKAGDNPHLWYDPATMPAAARALAAALGSADPAHKAEYDANLAKFVA
SMKPIDAKVAGLRARYKGVPVTATEPVFGYMADAIGLDMRNPRFQLATMNNTEASPADIAAFENDLKRRQVRVLIYNSQA
VEPMTKRMLKLAQDARVPTVSVTETQPAGKTFQQWMLAQLDALGAALGKRP
>Mature_291_residues
MRAARALAAGVAALALASAAFAQNATLKIVAAENFYGDVAKQIGGARVAVSSVLSNPDQDPHLFEASPKVARELQHADLV
IYNGADYDPWMAKLLAASKNAKRATVVVAELVGKKAGDNPHLWYDPATMPAAARALAAALGSADPAHKAEYDANLAKFVA
SMKPIDAKVAGLRARYKGVPVTATEPVFGYMADAIGLDMRNPRFQLATMNNTEASPADIAAFENDLKRRQVRVLIYNSQA
VEPMTKRMLKLAQDARVPTVSVTETQPAGKTFQQWMLAQLDALGAALGKRP

Specific function: Part of an ATP-driven transport system for manganese. Also act as an adhesin which is involved on adherence to extracellular matrix. It is an important factor in pathogenesis and infection [H]

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Cell membrane; Lipid-anchor [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family. Lipoprotein receptor antigen (Lrai) subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR006128 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 30980; Mature: 30980

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAARALAAGVAALALASAAFAQNATLKIVAAENFYGDVAKQIGGARVAVSSVLSNPDQD
CCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHCCHHHHHHHHHCCCCCC
PHLFEASPKVARELQHADLVIYNGADYDPWMAKLLAASKNAKRATVVVAELVGKKAGDNP
CCEECCCHHHHHHHHHCCEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCC
HLWYDPATMPAAARALAAALGSADPAHKAEYDANLAKFVASMKPIDAKVAGLRARYKGVP
CEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
VTATEPVFGYMADAIGLDMRNPRFQLATMNNTEASPADIAAFENDLKRRQVRVLIYNSQA
CCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCEEEEEEECCCC
VEPMTKRMLKLAQDARVPTVSVTETQPAGKTFQQWMLAQLDALGAALGKRP
CCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRAARALAAGVAALALASAAFAQNATLKIVAAENFYGDVAKQIGGARVAVSSVLSNPDQD
CCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHCCHHHHHHHHHCCCCCC
PHLFEASPKVARELQHADLVIYNGADYDPWMAKLLAASKNAKRATVVVAELVGKKAGDNP
CCEECCCHHHHHHHHHCCEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCC
HLWYDPATMPAAARALAAALGSADPAHKAEYDANLAKFVASMKPIDAKVAGLRARYKGVP
CEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
VTATEPVFGYMADAIGLDMRNPRFQLATMNNTEASPADIAAFENDLKRRQVRVLIYNSQA
CCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCEEEEEEECCCC
VEPMTKRMLKLAQDARVPTVSVTETQPAGKTFQQWMLAQLDALGAALGKRP
CCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8945574; 9767595; 11463916; 9379902 [H]