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The map label for this gene is aroA

Identifier: 53718326

GI number: 53718326

Start: 777987

End: 779342

Strand: Reverse

Name: aroA

Synonym: BPSL0683

Alternate gene names: 53718326

Gene position: 779342-777987 (Counterclockwise)

Preceding gene: 53718327

Following gene: 53718325

Centisome position: 19.13

GC content: 66.96

Gene sequence:

>1356_bases
ATGACCACCAGCGATCGCCTCCAGCCGTCGTTCGTCGAAGTGAAGAACACCTCGACGCTCAGCGGCACCATCGATCTTCC
CGCGTCGAAGAGCTCGTCGACGCGCGCGCTCCTCACCGCGGCGCTCACGCCCGGCATCAGCACGATCCGCAACGTCGCGA
CGGGCTTCAACTCGAACGCGATGAAGCACAACTGCGAGCGGCTCGGCGCGTCGTTCTCGAGCGAGGGCGACACGACGGTC
GTCAAGGGCGTCGACGTGATGCACGTCGATCGCGAGATCGTCTTCGACCCGGGCAACTCCGGCGTCGTGCTGCGCCTGCT
GATGGGCGTCGCCGGCTACCTGCCGGACACCCGGTTCGTCACGCAATACCGCTATTCGCTCGGCGTGCGCTCGCAGGCGG
AGATGGTCGCCGCGCTGCGCCGGCTGAACGTCGAATGCGAAGCGGTCGGCCCCGAGGCGCGGCTGCCGATCAGCATGCGC
TCGACGCGCGCGCTCGGCAAGCACACCGAAGTGTCGTGCAAGAAGAGCTCGCAGTTCCTGAGCGGCCTGCTCTATCTCGG
CGCGATCGGCGAGCGCGATCTCGAGATCGACGTGGTCGATCACATCACCGCGCCGTCGATGGTGCATACGACGATCAACA
ATCTCGCGCACGCGGGCGTCGCCGTCGAATACGACGCGGCCTTTCGCCGCTTCTTCGTGCCGGGGCGCGATCGCTTCAAG
CCGTCCGAGTTCACGGTCGGCGCCGATCCGGCGAGCACGGCCGCGATCCTCGCGCTGTGCGGCTCGCTCGCGTCGGACGT
CACGCTCAACGGCTTCTTCGAGGAAGAGCTCGGCAGCGGCGCGGTGATCCGCTATCTGACCGATACCGGCACGCTGATCG
ACGAGTTGCCCGGCAACCGCATCCGCATCCGGGGCGGCGCATCGATCCGCGCGCAGGATTTCGACGGCTCGCTCGCGCCG
GACGCGGTGCCCGCGCTCGCCGGCCGCGCGGCGTTCGCCGAAGGCACGAGCACGTTCTACAACATCGAGCATATCCGCTA
CAAGGAATCGGACCGCATCTCGGATTTCCGCCGCGAACTCGACAAGCTCGGCGTGCGCTCCGAAGAAAAGCTCGATCAGT
TGATCATCCACGGCAATCCGCGCAGCTACCGCGGCGGCGCGGTCGTCGACGGCCACTACGATCACGGGCTCATCATGGCG
CTCACGACGATCGGCCTGCACTGCGAGCATCCGGTGCTGATCAAGGAGCCGCATCACGTCGGGCAGACGTATCCCGATTA
CTTCGCCGACATCGGCTCGATCGGCGCGAACGTCGACGGGCTGATCTACCCGAACGTCGCCGCGGCGCGCGCATGA

Upstream 100 bases:

>100_bases
TCGACGACGGATTTCCGAAATTCATCGACACCCTGAGGGCGCTGGGCGCCGAAATCGCCTAGCCGGCCGGCCCCACGCCC
ATTCACGATACGGAGTAGCC

Downstream 100 bases:

>100_bases
ACGCGGCCCGCGCCATCGAATCCACTCACGAGAGAGAAATGACATGTGCGGAATTGGGGCCATTTTCAGCACGCAGCGCG
CGTCGGTCGACGGCATCGAG

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MTTSDRLQPSFVEVKNTSTLSGTIDLPASKSSSTRALLTAALTPGISTIRNVATGFNSNAMKHNCERLGASFSSEGDTTV
VKGVDVMHVDREIVFDPGNSGVVLRLLMGVAGYLPDTRFVTQYRYSLGVRSQAEMVAALRRLNVECEAVGPEARLPISMR
STRALGKHTEVSCKKSSQFLSGLLYLGAIGERDLEIDVVDHITAPSMVHTTINNLAHAGVAVEYDAAFRRFFVPGRDRFK
PSEFTVGADPASTAAILALCGSLASDVTLNGFFEEELGSGAVIRYLTDTGTLIDELPGNRIRIRGGASIRAQDFDGSLAP
DAVPALAGRAAFAEGTSTFYNIEHIRYKESDRISDFRRELDKLGVRSEEKLDQLIIHGNPRSYRGGAVVDGHYDHGLIMA
LTTIGLHCEHPVLIKEPHHVGQTYPDYFADIGSIGANVDGLIYPNVAAARA

Sequences:

>Translated_451_residues
MTTSDRLQPSFVEVKNTSTLSGTIDLPASKSSSTRALLTAALTPGISTIRNVATGFNSNAMKHNCERLGASFSSEGDTTV
VKGVDVMHVDREIVFDPGNSGVVLRLLMGVAGYLPDTRFVTQYRYSLGVRSQAEMVAALRRLNVECEAVGPEARLPISMR
STRALGKHTEVSCKKSSQFLSGLLYLGAIGERDLEIDVVDHITAPSMVHTTINNLAHAGVAVEYDAAFRRFFVPGRDRFK
PSEFTVGADPASTAAILALCGSLASDVTLNGFFEEELGSGAVIRYLTDTGTLIDELPGNRIRIRGGASIRAQDFDGSLAP
DAVPALAGRAAFAEGTSTFYNIEHIRYKESDRISDFRRELDKLGVRSEEKLDQLIIHGNPRSYRGGAVVDGHYDHGLIMA
LTTIGLHCEHPVLIKEPHHVGQTYPDYFADIGSIGANVDGLIYPNVAAARA
>Mature_450_residues
TTSDRLQPSFVEVKNTSTLSGTIDLPASKSSSTRALLTAALTPGISTIRNVATGFNSNAMKHNCERLGASFSSEGDTTVV
KGVDVMHVDREIVFDPGNSGVVLRLLMGVAGYLPDTRFVTQYRYSLGVRSQAEMVAALRRLNVECEAVGPEARLPISMRS
TRALGKHTEVSCKKSSQFLSGLLYLGAIGERDLEIDVVDHITAPSMVHTTINNLAHAGVAVEYDAAFRRFFVPGRDRFKP
SEFTVGADPASTAAILALCGSLASDVTLNGFFEEELGSGAVIRYLTDTGTLIDELPGNRIRIRGGASIRAQDFDGSLAPD
AVPALAGRAAFAEGTSTFYNIEHIRYKESDRISDFRRELDKLGVRSEEKLDQLIIHGNPRSYRGGAVVDGHYDHGLIMAL
TTIGLHCEHPVLIKEPHHVGQTYPDYFADIGSIGANVDGLIYPNVAAARA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family

Homologues:

Organism=Escherichia coli, GI1787137, Length=426, Percent_Identity=27.6995305164319, Blast_Score=112, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6320332, Length=462, Percent_Identity=26.6233766233766, Blast_Score=90, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROA1_BURPS (Q63X54)

Other databases:

- EMBL:   BX571965
- RefSeq:   YP_107312.1
- ProteinModelPortal:   Q63X54
- SMR:   Q63X54
- GeneID:   3094478
- GenomeReviews:   BX571965_GR
- KEGG:   bps:BPSL0683
- NMPDR:   fig|272560.3.peg.2516
- HOGENOM:   HBG646626
- OMA:   DVEIRAD
- ProtClustDB:   PRK02427
- BioCyc:   BPSE272560:BPSL0683-MONOMER
- BRENDA:   2.5.1.19
- GO:   GO:0005737
- HAMAP:   MF_00210
- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792
- Gene3D:   G3DSA:3.65.10.10
- PIRSF:   PIRSF000505

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.19

Molecular weight: Translated: 48628; Mature: 48496

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS00104 EPSP_SYNTHASE_1; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSDRLQPSFVEVKNTSTLSGTIDLPASKSSSTRALLTAALTPGISTIRNVATGFNSNA
CCCCCCCCCCEEEEECCCEEEEEEECCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCH
MKHNCERLGASFSSEGDTTVVKGVDVMHVDREIVFDPGNSGVVLRLLMGVAGYLPDTRFV
HHHHHHHHCCCCCCCCCEEEEECCEEEEECCEEEECCCCCHHHHHHHHHHHHCCCCCHHH
TQYRYSLGVRSQAEMVAALRRLNVECEAVGPEARLPISMRSTRALGKHTEVSCKKSSQFL
HHHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCCCCEEHHHHHHCCCCCCCCHHHHHHHH
SGLLYLGAIGERDLEIDVVDHITAPSMVHTTINNLAHAGVAVEYDAAFRRFFVPGRDRFK
HHHHHHHCCCCCCCEEEEHHCCCCCHHHHHHHHHHHHCCEEEEEHHHHHHEECCCCCCCC
PSEFTVGADPASTAAILALCGSLASDVTLNGFFEEELGSGAVIRYLTDTGTLIDELPGNR
CCCEEECCCCHHHHHHHHHHHHHHCCCEECCEEHHHCCCCEEEEEECCCCHHHHHCCCCE
IRIRGGASIRAQDFDGSLAPDAVPALAGRAAFAEGTSTFYNIEHIRYKESDRISDFRREL
EEEECCCEEEEECCCCCCCCCHHHHHHCCHHHCCCCCEEEEEEEEEECCCHHHHHHHHHH
DKLGVRSEEKLDQLIIHGNPRSYRGGAVVDGHYDHGLIMALTTIGLHCEHPVLIKEPHHV
HHHCCCCHHHHCEEEEECCCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEEECCCCC
GQTYPDYFADIGSIGANVDGLIYPNVAAARA
CCCCHHHHHHHHHCCCCCCCEECCCHHHCCC
>Mature Secondary Structure 
TTSDRLQPSFVEVKNTSTLSGTIDLPASKSSSTRALLTAALTPGISTIRNVATGFNSNA
CCCCCCCCCEEEEECCCEEEEEEECCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCH
MKHNCERLGASFSSEGDTTVVKGVDVMHVDREIVFDPGNSGVVLRLLMGVAGYLPDTRFV
HHHHHHHHCCCCCCCCCEEEEECCEEEEECCEEEECCCCCHHHHHHHHHHHHCCCCCHHH
TQYRYSLGVRSQAEMVAALRRLNVECEAVGPEARLPISMRSTRALGKHTEVSCKKSSQFL
HHHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCCCCEEHHHHHHCCCCCCCCHHHHHHHH
SGLLYLGAIGERDLEIDVVDHITAPSMVHTTINNLAHAGVAVEYDAAFRRFFVPGRDRFK
HHHHHHHCCCCCCCEEEEHHCCCCCHHHHHHHHHHHHCCEEEEEHHHHHHEECCCCCCCC
PSEFTVGADPASTAAILALCGSLASDVTLNGFFEEELGSGAVIRYLTDTGTLIDELPGNR
CCCEEECCCCHHHHHHHHHHHHHHCCCEECCEEHHHCCCCEEEEEECCCCHHHHHCCCCE
IRIRGGASIRAQDFDGSLAPDAVPALAGRAAFAEGTSTFYNIEHIRYKESDRISDFRREL
EEEECCCEEEEECCCCCCCCCHHHHHHCCHHHCCCCCEEEEEEEEEECCCHHHHHHHHHH
DKLGVRSEEKLDQLIIHGNPRSYRGGAVVDGHYDHGLIMALTTIGLHCEHPVLIKEPHHV
HHHCCCCHHHHCEEEEECCCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEEECCCCC
GQTYPDYFADIGSIGANVDGLIYPNVAAARA
CCCCHHHHHHHHHCCCCCCCEECCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA