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The map label for this gene is gpmA [H]

Identifier: 53718082

GI number: 53718082

Start: 483930

End: 484679

Strand: Reverse

Name: gpmA [H]

Synonym: BPSL0443

Alternate gene names: 53718082

Gene position: 484679-483930 (Counterclockwise)

Preceding gene: 53718088

Following gene: 53718081

Centisome position: 11.9

GC content: 67.07

Gene sequence:

>750_bases
ATGTACAAGCTCGTTCTCATCCGCCACGGCGAATCGACGTGGAACAAGGAAAACCGCTTCACCGGCTGGGTCGATGTCGA
CCTGACCGAACAAGGCAACCGCGAAGCCCGGCAGGCGGGCCAGCTCCTGAAGGAAGCCGGCTACACGTTCGATATCGCAT
ACACGTCGGTGCTCAAGCGCGCGATCCGCACGCTCTGGCACGTGCAGGACCAGATGGATCTGATGTACGTGCCCGTCGTG
CATTCGTGGCGCCTGAACGAGCGCCATTACGGCGCGCTGTCGGGCCTGAACAAGGCGGAGACGGCCGCGAAGTACGGCGA
CGAGCAGGTGCTCGTCTGGCGCCGCAGCTACGACACGCCGCCGCCCGCGCTCGAGCCGGGCGACGAGCGCGCGCCGTACG
CCGATCCGCGCTACGCGAAGGTGCCGCGTGAGCAGTTGCCGCTCACCGAGTGCCTGAAGGACACGGTCGCGCGCGTGCTG
CCGCTCTGGAACGAATCGATCGCGCCCGCGGTGAAGGCCGGCAAGCAGGTGCTGATCGCCGCGCACGGCAACTCGCTGCG
CGCGCTGATCAAGTATCTCGACGGCATCTCCGACGCGGACATCGTCGGCCTGAACATCCCGAACGGCGTGCCGCTCGTCT
ACGAGCTCGACGAGAGCCTCACGCCCATCCGGCACTACTACCTCGGCGATCAGGAGGCGATCGCGAAGGCGCAGGCCGCC
GTCGCGCAGCAGGGCAAGTCCGCGGCGTAA

Upstream 100 bases:

>100_bases
GCAATCCCGCCATTATAAAATAACCGTCTGACGCGATGTCGCCCCGGAGCCGGGTCCGCATCCGTGCTTACCGCTTCCTC
ACTACCGACCGCAAGCATCT

Downstream 100 bases:

>100_bases
GCCGCCGTTTCGCCGCGCGGGCGACGGCAGGTTCCGCGCCGTCCCCGTCGCCGGCGCGCGCCGCGCGAACCTGTTTCGCG
CGGCGCTGTCACAATCACGC

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MYKLVLIRHGESTWNKENRFTGWVDVDLTEQGNREARQAGQLLKEAGYTFDIAYTSVLKRAIRTLWHVQDQMDLMYVPVV
HSWRLNERHYGALSGLNKAETAAKYGDEQVLVWRRSYDTPPPALEPGDERAPYADPRYAKVPREQLPLTECLKDTVARVL
PLWNESIAPAVKAGKQVLIAAHGNSLRALIKYLDGISDADIVGLNIPNGVPLVYELDESLTPIRHYYLGDQEAIAKAQAA
VAQQGKSAA

Sequences:

>Translated_249_residues
MYKLVLIRHGESTWNKENRFTGWVDVDLTEQGNREARQAGQLLKEAGYTFDIAYTSVLKRAIRTLWHVQDQMDLMYVPVV
HSWRLNERHYGALSGLNKAETAAKYGDEQVLVWRRSYDTPPPALEPGDERAPYADPRYAKVPREQLPLTECLKDTVARVL
PLWNESIAPAVKAGKQVLIAAHGNSLRALIKYLDGISDADIVGLNIPNGVPLVYELDESLTPIRHYYLGDQEAIAKAQAA
VAQQGKSAA
>Mature_249_residues
MYKLVLIRHGESTWNKENRFTGWVDVDLTEQGNREARQAGQLLKEAGYTFDIAYTSVLKRAIRTLWHVQDQMDLMYVPVV
HSWRLNERHYGALSGLNKAETAAKYGDEQVLVWRRSYDTPPPALEPGDERAPYADPRYAKVPREQLPLTECLKDTVARVL
PLWNESIAPAVKAGKQVLIAAHGNSLRALIKYLDGISDADIVGLNIPNGVPLVYELDESLTPIRHYYLGDQEAIAKAQAA
VAQQGKSAA

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=252, Percent_Identity=57.9365079365079, Blast_Score=312, Evalue=1e-85,
Organism=Homo sapiens, GI4505753, Length=249, Percent_Identity=60.6425702811245, Blast_Score=303, Evalue=1e-82,
Organism=Homo sapiens, GI71274132, Length=249, Percent_Identity=59.0361445783133, Blast_Score=289, Evalue=2e-78,
Organism=Homo sapiens, GI4502445, Length=250, Percent_Identity=52.4, Blast_Score=267, Evalue=6e-72,
Organism=Homo sapiens, GI40353764, Length=250, Percent_Identity=52.4, Blast_Score=267, Evalue=6e-72,
Organism=Homo sapiens, GI310129614, Length=162, Percent_Identity=62.962962962963, Blast_Score=199, Evalue=2e-51,
Organism=Escherichia coli, GI1786970, Length=245, Percent_Identity=64.8979591836735, Blast_Score=329, Evalue=1e-91,
Organism=Saccharomyces cerevisiae, GI6322697, Length=246, Percent_Identity=52.8455284552846, Blast_Score=246, Evalue=3e-66,
Organism=Saccharomyces cerevisiae, GI6324516, Length=286, Percent_Identity=33.2167832167832, Blast_Score=155, Evalue=7e-39,
Organism=Saccharomyces cerevisiae, GI6320183, Length=291, Percent_Identity=31.9587628865979, Blast_Score=144, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24646216, Length=250, Percent_Identity=53.2, Blast_Score=276, Evalue=8e-75,
Organism=Drosophila melanogaster, GI85725270, Length=250, Percent_Identity=53.6, Blast_Score=262, Evalue=2e-70,
Organism=Drosophila melanogaster, GI85725272, Length=250, Percent_Identity=53.6, Blast_Score=262, Evalue=2e-70,
Organism=Drosophila melanogaster, GI24650981, Length=250, Percent_Identity=53.6, Blast_Score=262, Evalue=2e-70,
Organism=Drosophila melanogaster, GI28571815, Length=251, Percent_Identity=42.6294820717131, Blast_Score=187, Evalue=5e-48,
Organism=Drosophila melanogaster, GI28571817, Length=251, Percent_Identity=42.6294820717131, Blast_Score=187, Evalue=7e-48,
Organism=Drosophila melanogaster, GI24648979, Length=251, Percent_Identity=42.6294820717131, Blast_Score=186, Evalue=9e-48,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 27893; Mature: 27893

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKLVLIRHGESTWNKENRFTGWVDVDLTEQGNREARQAGQLLKEAGYTFDIAYTSVLKR
CEEEEEEECCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCEEEHHHHHHHHH
AIRTLWHVQDQMDLMYVPVVHSWRLNERHYGALSGLNKAETAAKYGDEQVLVWRRSYDTP
HHHHHHHHHHCCCEEEECEEEEEECCCCHHHHHHCCCHHHHHHHCCCCEEEEEECCCCCC
PPALEPGDERAPYADPRYAKVPREQLPLTECLKDTVARVLPLWNESIAPAVKAGKQVLIA
CCCCCCCCCCCCCCCCCHHCCCHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEEE
AHGNSLRALIKYLDGISDADIVGLNIPNGVPLVYELDESLTPIRHYYLGDQEAIAKAQAA
ECCCHHHHHHHHHCCCCCCCEEEEECCCCCCEEEECCCCCCHHHHHHCCCHHHHHHHHHH
VAQQGKSAA
HHHCCCCCC
>Mature Secondary Structure
MYKLVLIRHGESTWNKENRFTGWVDVDLTEQGNREARQAGQLLKEAGYTFDIAYTSVLKR
CEEEEEEECCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCEEEHHHHHHHHH
AIRTLWHVQDQMDLMYVPVVHSWRLNERHYGALSGLNKAETAAKYGDEQVLVWRRSYDTP
HHHHHHHHHHCCCEEEECEEEEEECCCCHHHHHHCCCHHHHHHHCCCCEEEEEECCCCCC
PPALEPGDERAPYADPRYAKVPREQLPLTECLKDTVARVLPLWNESIAPAVKAGKQVLIA
CCCCCCCCCCCCCCCCCHHCCCHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEEE
AHGNSLRALIKYLDGISDADIVGLNIPNGVPLVYELDESLTPIRHYYLGDQEAIAKAQAA
ECCCHHHHHHHHHCCCCCCCEEEEECCCCCCEEEECCCCCCHHHHHHCCCHHHHHHHHHH
VAQQGKSAA
HHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA